JP2013545584A5 - - Google Patents
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- JP2013545584A5 JP2013545584A5 JP2013544705A JP2013544705A JP2013545584A5 JP 2013545584 A5 JP2013545584 A5 JP 2013545584A5 JP 2013544705 A JP2013544705 A JP 2013544705A JP 2013544705 A JP2013544705 A JP 2013544705A JP 2013545584 A5 JP2013545584 A5 JP 2013545584A5
- Authority
- JP
- Japan
- Prior art keywords
- pdgf
- composition according
- scaffolding material
- bone scaffolding
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000203 mixture Substances 0.000 claims 22
- 210000000988 bone and bone Anatomy 0.000 claims 14
- 239000000463 material Substances 0.000 claims 14
- 108010081589 Becaplermin Proteins 0.000 claims 6
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 claims 6
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 claims 6
- 230000004927 fusion Effects 0.000 claims 5
- 239000011159 matrix material Substances 0.000 claims 5
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 3
- 102000008186 Collagen Human genes 0.000 claims 2
- 108010035532 Collagen Proteins 0.000 claims 2
- 239000011230 binding agent Substances 0.000 claims 2
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 2
- 239000001506 calcium phosphate Substances 0.000 claims 2
- 235000011010 calcium phosphates Nutrition 0.000 claims 2
- 229920001436 collagen Polymers 0.000 claims 2
- 210000002805 bone matrix Anatomy 0.000 claims 1
- 230000012292 cell migration Effects 0.000 claims 1
- 238000002513 implantation Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 108010017843 platelet-derived growth factor A Proteins 0.000 claims 1
- 108010000685 platelet-derived growth factor AB Proteins 0.000 claims 1
- 108010017992 platelet-derived growth factor C Proteins 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42264910P | 2010-12-13 | 2010-12-13 | |
| US61/422,649 | 2010-12-13 | ||
| PCT/US2011/064698 WO2012082773A1 (en) | 2010-12-13 | 2011-12-13 | Compositions and methods for spine fusion procedures |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016211737A Division JP2017018710A (ja) | 2010-12-13 | 2016-10-28 | 脊椎固定術用の組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013545584A JP2013545584A (ja) | 2013-12-26 |
| JP2013545584A5 true JP2013545584A5 (enExample) | 2015-02-05 |
| JP6116484B2 JP6116484B2 (ja) | 2017-04-19 |
Family
ID=46245079
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013544705A Expired - Fee Related JP6116484B2 (ja) | 2010-12-13 | 2011-12-13 | 脊椎固定術用の組成物および方法 |
| JP2016211737A Pending JP2017018710A (ja) | 2010-12-13 | 2016-10-28 | 脊椎固定術用の組成物および方法 |
| JP2018139921A Pending JP2018161541A (ja) | 2010-12-13 | 2018-07-26 | 脊椎固定術用の組成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016211737A Pending JP2017018710A (ja) | 2010-12-13 | 2016-10-28 | 脊椎固定術用の組成物および方法 |
| JP2018139921A Pending JP2018161541A (ja) | 2010-12-13 | 2018-07-26 | 脊椎固定術用の組成物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20140308332A1 (enExample) |
| EP (1) | EP2651319A4 (enExample) |
| JP (3) | JP6116484B2 (enExample) |
| KR (3) | KR20140038348A (enExample) |
| CN (2) | CN103491888A (enExample) |
| AU (1) | AU2011343995A1 (enExample) |
| BR (1) | BR112013014686A2 (enExample) |
| CA (1) | CA2819258C (enExample) |
| MX (1) | MX362405B (enExample) |
| WO (1) | WO2012082773A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2013133813A (ru) | 2010-12-21 | 2015-01-27 | Конинклейке Филипс Электроникс Н.В. | Средства для выведения биомолекул из кровотока |
| BR112017003428A2 (pt) * | 2014-08-28 | 2017-11-28 | Bioventus Llc | substratos osteoindutivos aperfeiçoados e métodos para fazer os mesmos |
| MX2017004520A (es) * | 2014-10-14 | 2018-03-15 | Lynch Samuel | Composiciones para tratar heridas. |
| WO2016109555A1 (en) | 2014-12-29 | 2016-07-07 | Bioventus, Llc | Systems and methods for improved delivery of osteoinductive molecules in bone repair |
| WO2017019959A1 (en) * | 2015-07-30 | 2017-02-02 | Clarion Research Group | Formulations and methods for recovery from spinal surgery |
| CN108601864A (zh) | 2015-10-30 | 2018-09-28 | 佰欧维恩图斯有限责任公司 | 用于增强骨修复中骨诱导分子的递送的基质 |
| US12318475B2 (en) | 2016-03-14 | 2025-06-03 | The University Of Chicago | Injectable pastes based on oppositely charged polymer/calcium phosphate nanoparticles |
| KR20190018671A (ko) | 2016-06-10 | 2019-02-25 | 바이오벤터스 엘엘씨 | 다공성 금속성 구조물에 의한 단백질 전달 |
| US12042519B2 (en) * | 2017-07-14 | 2024-07-23 | The University Of Chicago | Freeze-dried formulations including nanoparticles and methods of freeze-drying |
| EP3938000A4 (en) * | 2019-03-14 | 2022-11-16 | BioMimetic Therapeutics, LLC | PLATELET DERIVED GROWTH FACTOR FORMULATIONS TO IMPROVE BONE FUSION |
| EP3795185A1 (en) * | 2019-09-23 | 2021-03-24 | Kuros Biosurgery AG | Bone graft material for use in a spinal fusion method |
| CN111481741A (zh) * | 2020-04-15 | 2020-08-04 | 花沐医疗科技(上海)有限公司 | 复合可吸收自锁定颈椎融合器及其制备方法 |
| KR102667977B1 (ko) | 2020-05-08 | 2024-05-22 | 주식회사 에이치엘클레무브 | 차량용 레이더 장치 및 제어방법 |
| WO2025042830A1 (en) | 2023-08-18 | 2025-02-27 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor bone graft putty formulation |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010037091A1 (en) * | 1999-12-29 | 2001-11-01 | Wironen John F. | System for reconstituting pastes and methods of using same |
| EP1335686B1 (en) * | 2000-10-24 | 2008-12-17 | Warsaw Orthopedic, Inc. | Spinal fusion devices |
| MXPA05008653A (es) * | 2003-02-14 | 2006-04-27 | Depuy Spine Inc | Dispositivo de fusion intervertebral formado in situ. |
| US20040193270A1 (en) * | 2003-03-31 | 2004-09-30 | Depuyacromed, Inc. | Implantable bone graft |
| CN1640368A (zh) * | 2004-01-06 | 2005-07-20 | 宋跃明 | 椎间融合装置 |
| US7901650B2 (en) * | 2005-06-22 | 2011-03-08 | Skeletal Kinectics, LLC | Porous beta-tricalcium phosphate and methods for producing the same |
| WO2007061889A2 (en) * | 2005-11-17 | 2007-05-31 | Biomimetic Therapeutics, Inc. | Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix |
| KR101105890B1 (ko) * | 2005-12-14 | 2012-01-16 | 에스씨아이엘 테크놀로지 게엠베하 | 골 재생을 위한 성형성 생체적응재료 |
| US9161967B2 (en) * | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| EP2462895B1 (en) * | 2006-11-03 | 2016-11-02 | BioMimetic Therapeutics, LLC | Compositions and methods for arthrodetic procedures |
| US20090048675A1 (en) * | 2007-04-25 | 2009-02-19 | Bhatnagar Mohit K | Spinal Fusion Implants with Selectively Applied Bone Growth Promoting Agent |
| US8241357B2 (en) * | 2007-04-25 | 2012-08-14 | Jmea Corporation | Prosthesis with a selectively applied bone growth promoting agent |
| CA2689986C (en) * | 2007-06-04 | 2020-04-07 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating the vertebral column |
| CN101121753B (zh) * | 2007-06-06 | 2011-11-16 | 天津林达生物科技有限公司 | 对多种皮肤细胞修复具持续作用的人血清白蛋白重组融合蛋白 |
| KR101634664B1 (ko) * | 2007-08-29 | 2016-06-29 | 에텍스 코포레이션 | 골 시멘트 혼합 및 전달 시스템 및 그의 사용 방법 |
| CA2715254A1 (en) * | 2008-02-07 | 2009-08-13 | Biomimetic Therapeutics, Inc. | Compositions and methods for distraction osteogenesis |
| JP2012519556A (ja) * | 2009-03-05 | 2012-08-30 | バイオミメティック セラピューティクス， インコーポレイテッド | 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法 |
-
2011
- 2011-12-13 WO PCT/US2011/064698 patent/WO2012082773A1/en not_active Ceased
- 2011-12-13 MX MX2013006697A patent/MX362405B/es active IP Right Grant
- 2011-12-13 KR KR1020137015102A patent/KR20140038348A/ko not_active Ceased
- 2011-12-13 US US13/992,033 patent/US20140308332A1/en not_active Abandoned
- 2011-12-13 CN CN201180067451.1A patent/CN103491888A/zh active Pending
- 2011-12-13 CN CN201810399549.0A patent/CN108498873A/zh active Pending
- 2011-12-13 EP EP11848160.5A patent/EP2651319A4/en not_active Withdrawn
- 2011-12-13 CA CA2819258A patent/CA2819258C/en active Active
- 2011-12-13 KR KR1020187031242A patent/KR20180121674A/ko not_active Ceased
- 2011-12-13 BR BR112013014686A patent/BR112013014686A2/pt not_active IP Right Cessation
- 2011-12-13 AU AU2011343995A patent/AU2011343995A1/en not_active Abandoned
- 2011-12-13 KR KR1020207013423A patent/KR20200055149A/ko not_active Ceased
- 2011-12-13 JP JP2013544705A patent/JP6116484B2/ja not_active Expired - Fee Related
-
2016
- 2016-10-28 JP JP2016211737A patent/JP2017018710A/ja active Pending
-
2018
- 2018-05-08 US US15/973,903 patent/US20190365946A1/en not_active Abandoned
- 2018-07-26 JP JP2018139921A patent/JP2018161541A/ja active Pending
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