KR20140038348A - 척추 유합 절차를 위한 조성물 및 방법 - Google Patents

척추 유합 절차를 위한 조성물 및 방법 Download PDF

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Publication number
KR20140038348A
KR20140038348A KR1020137015102A KR20137015102A KR20140038348A KR 20140038348 A KR20140038348 A KR 20140038348A KR 1020137015102 A KR1020137015102 A KR 1020137015102A KR 20137015102 A KR20137015102 A KR 20137015102A KR 20140038348 A KR20140038348 A KR 20140038348A
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South Korea
Prior art keywords
support material
bone support
composition
pdgf
micrometers
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Ceased
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KR1020137015102A
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English (en)
Korean (ko)
Inventor
사무엘 이. 린치
레오 비. 스넬
크리스토퍼 케이. 히
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바이오미메틱 세라퓨틱스, 엘엘씨
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Publication of KR20140038348A publication Critical patent/KR20140038348A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608Bone, e.g. demineralised bone matrix [DBM], bone powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/24Materials or treatment for tissue regeneration for joint reconstruction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/38Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Composite Materials (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020137015102A 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법 Ceased KR20140038348A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42264910P 2010-12-13 2010-12-13
US61/422,649 2010-12-13
PCT/US2011/064698 WO2012082773A1 (en) 2010-12-13 2011-12-13 Compositions and methods for spine fusion procedures

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187031242A Division KR20180121674A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법

Publications (1)

Publication Number Publication Date
KR20140038348A true KR20140038348A (ko) 2014-03-28

Family

ID=46245079

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020137015102A Ceased KR20140038348A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법
KR1020187031242A Ceased KR20180121674A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법
KR1020207013423A Ceased KR20200055149A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020187031242A Ceased KR20180121674A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법
KR1020207013423A Ceased KR20200055149A (ko) 2010-12-13 2011-12-13 척추 유합 절차를 위한 조성물 및 방법

Country Status (10)

Country Link
US (2) US20140308332A1 (enExample)
EP (1) EP2651319A4 (enExample)
JP (3) JP6116484B2 (enExample)
KR (3) KR20140038348A (enExample)
CN (2) CN103491888A (enExample)
AU (1) AU2011343995A1 (enExample)
BR (1) BR112013014686A2 (enExample)
CA (1) CA2819258C (enExample)
MX (1) MX362405B (enExample)
WO (1) WO2012082773A1 (enExample)

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RU2013133813A (ru) 2010-12-21 2015-01-27 Конинклейке Филипс Электроникс Н.В. Средства для выведения биомолекул из кровотока
BR112017003428A2 (pt) * 2014-08-28 2017-11-28 Bioventus Llc substratos osteoindutivos aperfeiçoados e métodos para fazer os mesmos
MX2017004520A (es) * 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
WO2016109555A1 (en) 2014-12-29 2016-07-07 Bioventus, Llc Systems and methods for improved delivery of osteoinductive molecules in bone repair
WO2017019959A1 (en) * 2015-07-30 2017-02-02 Clarion Research Group Formulations and methods for recovery from spinal surgery
CN108601864A (zh) 2015-10-30 2018-09-28 佰欧维恩图斯有限责任公司 用于增强骨修复中骨诱导分子的递送的基质
US12318475B2 (en) 2016-03-14 2025-06-03 The University Of Chicago Injectable pastes based on oppositely charged polymer/calcium phosphate nanoparticles
KR20190018671A (ko) 2016-06-10 2019-02-25 바이오벤터스 엘엘씨 다공성 금속성 구조물에 의한 단백질 전달
US12042519B2 (en) * 2017-07-14 2024-07-23 The University Of Chicago Freeze-dried formulations including nanoparticles and methods of freeze-drying
EP3938000A4 (en) * 2019-03-14 2022-11-16 BioMimetic Therapeutics, LLC PLATELET DERIVED GROWTH FACTOR FORMULATIONS TO IMPROVE BONE FUSION
EP3795185A1 (en) * 2019-09-23 2021-03-24 Kuros Biosurgery AG Bone graft material for use in a spinal fusion method
CN111481741A (zh) * 2020-04-15 2020-08-04 花沐医疗科技(上海)有限公司 复合可吸收自锁定颈椎融合器及其制备方法
KR102667977B1 (ko) 2020-05-08 2024-05-22 주식회사 에이치엘클레무브 차량용 레이더 장치 및 제어방법
WO2025042830A1 (en) 2023-08-18 2025-02-27 Biomimetic Therapeutics, Llc Platelet-derived growth factor bone graft putty formulation

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US20010037091A1 (en) * 1999-12-29 2001-11-01 Wironen John F. System for reconstituting pastes and methods of using same
EP1335686B1 (en) * 2000-10-24 2008-12-17 Warsaw Orthopedic, Inc. Spinal fusion devices
MXPA05008653A (es) * 2003-02-14 2006-04-27 Depuy Spine Inc Dispositivo de fusion intervertebral formado in situ.
US20040193270A1 (en) * 2003-03-31 2004-09-30 Depuyacromed, Inc. Implantable bone graft
CN1640368A (zh) * 2004-01-06 2005-07-20 宋跃明 椎间融合装置
US7901650B2 (en) * 2005-06-22 2011-03-08 Skeletal Kinectics, LLC Porous beta-tricalcium phosphate and methods for producing the same
WO2007061889A2 (en) * 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
KR101105890B1 (ko) * 2005-12-14 2012-01-16 에스씨아이엘 테크놀로지 게엠베하 골 재생을 위한 성형성 생체적응재료
US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
EP2462895B1 (en) * 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
US20090048675A1 (en) * 2007-04-25 2009-02-19 Bhatnagar Mohit K Spinal Fusion Implants with Selectively Applied Bone Growth Promoting Agent
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CA2689986C (en) * 2007-06-04 2020-04-07 Biomimetic Therapeutics, Inc. Compositions and methods for treating the vertebral column
CN101121753B (zh) * 2007-06-06 2011-11-16 天津林达生物科技有限公司 对多种皮肤细胞修复具持续作用的人血清白蛋白重组融合蛋白
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Also Published As

Publication number Publication date
JP6116484B2 (ja) 2017-04-19
AU2011343995A1 (en) 2013-06-20
BR112013014686A2 (pt) 2016-10-04
KR20180121674A (ko) 2018-11-07
CN108498873A (zh) 2018-09-07
JP2017018710A (ja) 2017-01-26
KR20200055149A (ko) 2020-05-20
WO2012082773A1 (en) 2012-06-21
EP2651319A1 (en) 2013-10-23
US20140308332A1 (en) 2014-10-16
JP2018161541A (ja) 2018-10-18
MX362405B (es) 2019-01-15
MX2013006697A (es) 2013-10-30
CA2819258C (en) 2020-03-10
CN103491888A (zh) 2014-01-01
EP2651319A4 (en) 2016-08-17
US20190365946A1 (en) 2019-12-05
JP2013545584A (ja) 2013-12-26
CA2819258A1 (en) 2012-06-21

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