MX362405B - Composiciones y metodos para procedimientos de fusion de espina. - Google Patents

Composiciones y metodos para procedimientos de fusion de espina.

Info

Publication number
MX362405B
MX362405B MX2013006697A MX2013006697A MX362405B MX 362405 B MX362405 B MX 362405B MX 2013006697 A MX2013006697 A MX 2013006697A MX 2013006697 A MX2013006697 A MX 2013006697A MX 362405 B MX362405 B MX 362405B
Authority
MX
Mexico
Prior art keywords
spine fusion
methods
compositions
fusion procedures
spine
Prior art date
Application number
MX2013006697A
Other languages
English (en)
Other versions
MX2013006697A (es
Inventor
E Lynch Samuel
B Snel Leo
K Hee Christopher
Original Assignee
Biomimetic Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomimetic Therapeutics Llc filed Critical Biomimetic Therapeutics Llc
Publication of MX2013006697A publication Critical patent/MX2013006697A/es
Publication of MX362405B publication Critical patent/MX362405B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Abstract

La presente invención proporciona una composición que comprende una matriz biocompatible y una solución de factor de crecimiento derivado de plaquetas (PDGF) a una concentración que varía de 0.1 a 1.0 mg/mL para usarse en un procedimiento de fusión vertebral intercuerpo, en donde la solución es incorporada en la matriz biocompatible, en donde la matriz biocompatible comprende un material de andamio de hueso y el material de andamio de hueso comprende partículas de un fosfato de calcio poroso teniendo un tamaño promedio variando de 50 a 5,000 micras, en donde la composición está adapatada para administrar la matriz biocompatible y la solución a un sitio de fusión de espina deseado de manera que la fusión ósea es acelerada.
MX2013006697A 2010-12-13 2011-12-13 Composiciones y metodos para procedimientos de fusion de espina. MX362405B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42264910P 2010-12-13 2010-12-13
PCT/US2011/064698 WO2012082773A1 (en) 2010-12-13 2011-12-13 Compositions and methods for spine fusion procedures

Publications (2)

Publication Number Publication Date
MX2013006697A MX2013006697A (es) 2013-10-30
MX362405B true MX362405B (es) 2019-01-15

Family

ID=46245079

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013006697A MX362405B (es) 2010-12-13 2011-12-13 Composiciones y metodos para procedimientos de fusion de espina.

Country Status (10)

Country Link
US (2) US20140308332A1 (es)
EP (1) EP2651319A4 (es)
JP (3) JP6116484B2 (es)
KR (3) KR20140038348A (es)
CN (2) CN103491888A (es)
AU (1) AU2011343995A1 (es)
BR (1) BR112013014686A2 (es)
CA (1) CA2819258C (es)
MX (1) MX362405B (es)
WO (1) WO2012082773A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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US9427482B2 (en) 2010-12-21 2016-08-30 Koninklijke Philips N.V. Agents for clearing biomolecules from circulation
WO2016043955A1 (en) * 2014-08-28 2016-03-24 Bioventus, Llc Improved osteoinductive substrates and methods of making the same
CA2962954A1 (en) 2014-10-14 2016-04-21 Samuel Lynch Compositions for treating wounds
AU2015374114B2 (en) 2014-12-29 2018-07-26 Bioventus, Llc Systems and methods for improved delivery of osteoinductive molecules in bone repair
WO2017019959A1 (en) * 2015-07-30 2017-02-02 Clarion Research Group Formulations and methods for recovery from spinal surgery
KR20180079368A (ko) 2015-10-30 2018-07-10 바이오벤터스 엘엘씨 골 복구에서 골유도 분자의 증진된 전달을 위한 매트릭스
CN109310801A (zh) 2016-06-10 2019-02-05 佰欧维恩图斯有限责任公司 使用多孔金属结构的蛋白递送
WO2020186267A2 (en) * 2019-03-14 2020-09-17 Biomimetic Therapeutics, Llc Platelet-derived growth factor formulations for enhancing bone fusion
CN111481741A (zh) * 2020-04-15 2020-08-04 花沐医疗科技(上海)有限公司 复合可吸收自锁定颈椎融合器及其制备方法
KR20210136629A (ko) 2020-05-08 2021-11-17 주식회사 만도모빌리티솔루션즈 차량용 레이더 장치 및 제어방법

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010037091A1 (en) * 1999-12-29 2001-11-01 Wironen John F. System for reconstituting pastes and methods of using same
AU2002225862B2 (en) * 2000-10-24 2005-05-12 Warsaw Orthopedic, Inc. Spinal fusion methods and devices
MXPA05008653A (es) * 2003-02-14 2006-04-27 Depuy Spine Inc Dispositivo de fusion intervertebral formado in situ.
US20040193270A1 (en) * 2003-03-31 2004-09-30 Depuyacromed, Inc. Implantable bone graft
CN1640368A (zh) * 2004-01-06 2005-07-20 宋跃明 椎间融合装置
US7901650B2 (en) * 2005-06-22 2011-03-08 Skeletal Kinectics, LLC Porous beta-tricalcium phosphate and methods for producing the same
NZ571113A (en) * 2005-11-17 2012-02-24 Biomimetic Therapeutics Inc Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
KR101105890B1 (ko) * 2005-12-14 2012-01-16 에스씨아이엘 테크놀로지 게엠베하 골 재생을 위한 성형성 생체적응재료
US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
AU2007333425B2 (en) * 2006-11-03 2014-03-27 Biomimetic Therapeutics, Llc Compositions and methods for arthrodetic procedures
US20090048675A1 (en) * 2007-04-25 2009-02-19 Bhatnagar Mohit K Spinal Fusion Implants with Selectively Applied Bone Growth Promoting Agent
US8241357B2 (en) * 2007-04-25 2012-08-14 Jmea Corporation Prosthesis with a selectively applied bone growth promoting agent
CN106110299A (zh) * 2007-06-04 2016-11-16 生物模拟治疗公司 用于治疗脊柱的组合物和方法
CN101121753B (zh) * 2007-06-06 2011-11-16 天津林达生物科技有限公司 对多种皮肤细胞修复具持续作用的人血清白蛋白重组融合蛋白
CN101835434A (zh) * 2007-08-29 2010-09-15 埃泰克斯公司 骨水泥混合和递送系统及其应用方法
CN102014977B (zh) * 2008-02-07 2015-09-02 生物模拟治疗有限责任公司 用于牵引成骨术的组合物和方法
CA2754501A1 (en) * 2009-03-05 2010-09-10 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects

Also Published As

Publication number Publication date
CN103491888A (zh) 2014-01-01
KR20200055149A (ko) 2020-05-20
AU2011343995A1 (en) 2013-06-20
CA2819258C (en) 2020-03-10
EP2651319A4 (en) 2016-08-17
WO2012082773A1 (en) 2012-06-21
EP2651319A1 (en) 2013-10-23
JP6116484B2 (ja) 2017-04-19
JP2013545584A (ja) 2013-12-26
US20190365946A1 (en) 2019-12-05
US20140308332A1 (en) 2014-10-16
KR20180121674A (ko) 2018-11-07
CA2819258A1 (en) 2012-06-21
KR20140038348A (ko) 2014-03-28
JP2018161541A (ja) 2018-10-18
JP2017018710A (ja) 2017-01-26
CN108498873A (zh) 2018-09-07
BR112013014686A2 (pt) 2016-10-04
MX2013006697A (es) 2013-10-30

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