AU2011343995A1 - Compositions and methods for spine fusion procedures - Google Patents

Compositions and methods for spine fusion procedures Download PDF

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Publication number
AU2011343995A1
AU2011343995A1 AU2011343995A AU2011343995A AU2011343995A1 AU 2011343995 A1 AU2011343995 A1 AU 2011343995A1 AU 2011343995 A AU2011343995 A AU 2011343995A AU 2011343995 A AU2011343995 A AU 2011343995A AU 2011343995 A1 AU2011343995 A1 AU 2011343995A1
Authority
AU
Australia
Prior art keywords
bone scaffolding
pdgf
scaffolding material
microns
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2011343995A
Other languages
English (en)
Inventor
Christopher K. Hee
Samuel E. Lynch
Leo B. Snel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomimetic Therapeutics LLC
Original Assignee
Biomimetic Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomimetic Therapeutics LLC filed Critical Biomimetic Therapeutics LLC
Publication of AU2011343995A1 publication Critical patent/AU2011343995A1/en
Assigned to BIOMIMETIC THERAPEUTICS, LLC reassignment BIOMIMETIC THERAPEUTICS, LLC Amend patent request/document other than specification (104) Assignors: BIOMIMETIC THERAPEUTICS, INC.
Priority to AU2015249136A priority Critical patent/AU2015249136A1/en
Priority to AU2017213462A priority patent/AU2017213462A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Composite Materials (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2011343995A 2010-12-13 2011-12-13 Compositions and methods for spine fusion procedures Abandoned AU2011343995A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2015249136A AU2015249136A1 (en) 2010-12-13 2015-10-29 Compositions and methods for spine fusion procedures
AU2017213462A AU2017213462A1 (en) 2010-12-13 2017-08-08 Compositions and methods for spine fusion procedures

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42264910P 2010-12-13 2010-12-13
US61/422,649 2010-12-13
PCT/US2011/064698 WO2012082773A1 (en) 2010-12-13 2011-12-13 Compositions and methods for spine fusion procedures

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2015249136A Division AU2015249136A1 (en) 2010-12-13 2015-10-29 Compositions and methods for spine fusion procedures

Publications (1)

Publication Number Publication Date
AU2011343995A1 true AU2011343995A1 (en) 2013-06-20

Family

ID=46245079

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2011343995A Abandoned AU2011343995A1 (en) 2010-12-13 2011-12-13 Compositions and methods for spine fusion procedures

Country Status (10)

Country Link
US (2) US20140308332A1 (enExample)
EP (1) EP2651319A4 (enExample)
JP (3) JP6116484B2 (enExample)
KR (3) KR20140038348A (enExample)
CN (2) CN103491888A (enExample)
AU (1) AU2011343995A1 (enExample)
BR (1) BR112013014686A2 (enExample)
CA (1) CA2819258C (enExample)
MX (1) MX362405B (enExample)
WO (1) WO2012082773A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2013133813A (ru) 2010-12-21 2015-01-27 Конинклейке Филипс Электроникс Н.В. Средства для выведения биомолекул из кровотока
BR112017003428A2 (pt) * 2014-08-28 2017-11-28 Bioventus Llc substratos osteoindutivos aperfeiçoados e métodos para fazer os mesmos
MX2017004520A (es) * 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
WO2016109555A1 (en) 2014-12-29 2016-07-07 Bioventus, Llc Systems and methods for improved delivery of osteoinductive molecules in bone repair
WO2017019959A1 (en) * 2015-07-30 2017-02-02 Clarion Research Group Formulations and methods for recovery from spinal surgery
CN108601864A (zh) 2015-10-30 2018-09-28 佰欧维恩图斯有限责任公司 用于增强骨修复中骨诱导分子的递送的基质
US12318475B2 (en) 2016-03-14 2025-06-03 The University Of Chicago Injectable pastes based on oppositely charged polymer/calcium phosphate nanoparticles
KR20190018671A (ko) 2016-06-10 2019-02-25 바이오벤터스 엘엘씨 다공성 금속성 구조물에 의한 단백질 전달
US12042519B2 (en) * 2017-07-14 2024-07-23 The University Of Chicago Freeze-dried formulations including nanoparticles and methods of freeze-drying
EP3938000A4 (en) * 2019-03-14 2022-11-16 BioMimetic Therapeutics, LLC PLATELET DERIVED GROWTH FACTOR FORMULATIONS TO IMPROVE BONE FUSION
EP3795185A1 (en) * 2019-09-23 2021-03-24 Kuros Biosurgery AG Bone graft material for use in a spinal fusion method
CN111481741A (zh) * 2020-04-15 2020-08-04 花沐医疗科技(上海)有限公司 复合可吸收自锁定颈椎融合器及其制备方法
KR102667977B1 (ko) 2020-05-08 2024-05-22 주식회사 에이치엘클레무브 차량용 레이더 장치 및 제어방법
WO2025042830A1 (en) 2023-08-18 2025-02-27 Biomimetic Therapeutics, Llc Platelet-derived growth factor bone graft putty formulation

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010037091A1 (en) * 1999-12-29 2001-11-01 Wironen John F. System for reconstituting pastes and methods of using same
EP1335686B1 (en) * 2000-10-24 2008-12-17 Warsaw Orthopedic, Inc. Spinal fusion devices
MXPA05008653A (es) * 2003-02-14 2006-04-27 Depuy Spine Inc Dispositivo de fusion intervertebral formado in situ.
US20040193270A1 (en) * 2003-03-31 2004-09-30 Depuyacromed, Inc. Implantable bone graft
CN1640368A (zh) * 2004-01-06 2005-07-20 宋跃明 椎间融合装置
US7901650B2 (en) * 2005-06-22 2011-03-08 Skeletal Kinectics, LLC Porous beta-tricalcium phosphate and methods for producing the same
WO2007061889A2 (en) * 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
KR101105890B1 (ko) * 2005-12-14 2012-01-16 에스씨아이엘 테크놀로지 게엠베하 골 재생을 위한 성형성 생체적응재료
US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
EP2462895B1 (en) * 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
US20090048675A1 (en) * 2007-04-25 2009-02-19 Bhatnagar Mohit K Spinal Fusion Implants with Selectively Applied Bone Growth Promoting Agent
US8241357B2 (en) * 2007-04-25 2012-08-14 Jmea Corporation Prosthesis with a selectively applied bone growth promoting agent
CA2689986C (en) * 2007-06-04 2020-04-07 Biomimetic Therapeutics, Inc. Compositions and methods for treating the vertebral column
CN101121753B (zh) * 2007-06-06 2011-11-16 天津林达生物科技有限公司 对多种皮肤细胞修复具持续作用的人血清白蛋白重组融合蛋白
KR101634664B1 (ko) * 2007-08-29 2016-06-29 에텍스 코포레이션 골 시멘트 혼합 및 전달 시스템 및 그의 사용 방법
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JP2012519556A (ja) * 2009-03-05 2012-08-30 バイオミメティック セラピューティクス， インコーポレイテッド 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法

Also Published As

Publication number Publication date
JP6116484B2 (ja) 2017-04-19
BR112013014686A2 (pt) 2016-10-04
KR20180121674A (ko) 2018-11-07
CN108498873A (zh) 2018-09-07
JP2017018710A (ja) 2017-01-26
KR20200055149A (ko) 2020-05-20
WO2012082773A1 (en) 2012-06-21
EP2651319A1 (en) 2013-10-23
US20140308332A1 (en) 2014-10-16
JP2018161541A (ja) 2018-10-18
MX362405B (es) 2019-01-15
MX2013006697A (es) 2013-10-30
CA2819258C (en) 2020-03-10
CN103491888A (zh) 2014-01-01
KR20140038348A (ko) 2014-03-28
EP2651319A4 (en) 2016-08-17
US20190365946A1 (en) 2019-12-05
JP2013545584A (ja) 2013-12-26
CA2819258A1 (en) 2012-06-21

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MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted