CA2819258C - Compositions and methods for spine fusion procedures - Google Patents
Compositions and methods for spine fusion procedures Download PDFInfo
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- CA2819258C CA2819258C CA2819258A CA2819258A CA2819258C CA 2819258 C CA2819258 C CA 2819258C CA 2819258 A CA2819258 A CA 2819258A CA 2819258 A CA2819258 A CA 2819258A CA 2819258 C CA2819258 C CA 2819258C
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- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- YIGWVOWKHUSYER-UHFFFAOYSA-F tetracalcium;hydrogen phosphate;diphosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].OP([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O YIGWVOWKHUSYER-UHFFFAOYSA-F 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000003232 water-soluble binding agent Substances 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
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Classifications
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
- A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
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- Inorganic Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Materials Engineering (AREA)
- Urology & Nephrology (AREA)
- Botany (AREA)
- Composite Materials (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42264910P | 2010-12-13 | 2010-12-13 | |
| US61/422,649 | 2010-12-13 | ||
| PCT/US2011/064698 WO2012082773A1 (en) | 2010-12-13 | 2011-12-13 | Compositions and methods for spine fusion procedures |
Publications (2)
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| CA2819258A1 CA2819258A1 (en) | 2012-06-21 |
| CA2819258C true CA2819258C (en) | 2020-03-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2819258A Active CA2819258C (en) | 2010-12-13 | 2011-12-13 | Compositions and methods for spine fusion procedures |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20140308332A1 (enExample) |
| EP (1) | EP2651319A4 (enExample) |
| JP (3) | JP6116484B2 (enExample) |
| KR (3) | KR20140038348A (enExample) |
| CN (2) | CN103491888A (enExample) |
| AU (1) | AU2011343995A1 (enExample) |
| BR (1) | BR112013014686A2 (enExample) |
| CA (1) | CA2819258C (enExample) |
| MX (1) | MX362405B (enExample) |
| WO (1) | WO2012082773A1 (enExample) |
Families Citing this family (14)
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| RU2013133813A (ru) | 2010-12-21 | 2015-01-27 | Конинклейке Филипс Электроникс Н.В. | Средства для выведения биомолекул из кровотока |
| BR112017003428A2 (pt) * | 2014-08-28 | 2017-11-28 | Bioventus Llc | substratos osteoindutivos aperfeiçoados e métodos para fazer os mesmos |
| MX2017004520A (es) * | 2014-10-14 | 2018-03-15 | Lynch Samuel | Composiciones para tratar heridas. |
| WO2016109555A1 (en) | 2014-12-29 | 2016-07-07 | Bioventus, Llc | Systems and methods for improved delivery of osteoinductive molecules in bone repair |
| WO2017019959A1 (en) * | 2015-07-30 | 2017-02-02 | Clarion Research Group | Formulations and methods for recovery from spinal surgery |
| CN108601864A (zh) | 2015-10-30 | 2018-09-28 | 佰欧维恩图斯有限责任公司 | 用于增强骨修复中骨诱导分子的递送的基质 |
| US12318475B2 (en) | 2016-03-14 | 2025-06-03 | The University Of Chicago | Injectable pastes based on oppositely charged polymer/calcium phosphate nanoparticles |
| KR20190018671A (ko) | 2016-06-10 | 2019-02-25 | 바이오벤터스 엘엘씨 | 다공성 금속성 구조물에 의한 단백질 전달 |
| US12042519B2 (en) * | 2017-07-14 | 2024-07-23 | The University Of Chicago | Freeze-dried formulations including nanoparticles and methods of freeze-drying |
| EP3938000A4 (en) * | 2019-03-14 | 2022-11-16 | BioMimetic Therapeutics, LLC | PLATELET DERIVED GROWTH FACTOR FORMULATIONS TO IMPROVE BONE FUSION |
| EP3795185A1 (en) * | 2019-09-23 | 2021-03-24 | Kuros Biosurgery AG | Bone graft material for use in a spinal fusion method |
| CN111481741A (zh) * | 2020-04-15 | 2020-08-04 | 花沐医疗科技(上海)有限公司 | 复合可吸收自锁定颈椎融合器及其制备方法 |
| KR102667977B1 (ko) | 2020-05-08 | 2024-05-22 | 주식회사 에이치엘클레무브 | 차량용 레이더 장치 및 제어방법 |
| WO2025042830A1 (en) | 2023-08-18 | 2025-02-27 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor bone graft putty formulation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20010037091A1 (en) * | 1999-12-29 | 2001-11-01 | Wironen John F. | System for reconstituting pastes and methods of using same |
| EP1335686B1 (en) * | 2000-10-24 | 2008-12-17 | Warsaw Orthopedic, Inc. | Spinal fusion devices |
| MXPA05008653A (es) * | 2003-02-14 | 2006-04-27 | Depuy Spine Inc | Dispositivo de fusion intervertebral formado in situ. |
| US20040193270A1 (en) * | 2003-03-31 | 2004-09-30 | Depuyacromed, Inc. | Implantable bone graft |
| CN1640368A (zh) * | 2004-01-06 | 2005-07-20 | 宋跃明 | 椎间融合装置 |
| US7901650B2 (en) * | 2005-06-22 | 2011-03-08 | Skeletal Kinectics, LLC | Porous beta-tricalcium phosphate and methods for producing the same |
| WO2007061889A2 (en) * | 2005-11-17 | 2007-05-31 | Biomimetic Therapeutics, Inc. | Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix |
| KR101105890B1 (ko) * | 2005-12-14 | 2012-01-16 | 에스씨아이엘 테크놀로지 게엠베하 | 골 재생을 위한 성형성 생체적응재료 |
| US9161967B2 (en) * | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| EP2462895B1 (en) * | 2006-11-03 | 2016-11-02 | BioMimetic Therapeutics, LLC | Compositions and methods for arthrodetic procedures |
| US20090048675A1 (en) * | 2007-04-25 | 2009-02-19 | Bhatnagar Mohit K | Spinal Fusion Implants with Selectively Applied Bone Growth Promoting Agent |
| US8241357B2 (en) * | 2007-04-25 | 2012-08-14 | Jmea Corporation | Prosthesis with a selectively applied bone growth promoting agent |
| CA2689986C (en) * | 2007-06-04 | 2020-04-07 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating the vertebral column |
| CN101121753B (zh) * | 2007-06-06 | 2011-11-16 | 天津林达生物科技有限公司 | 对多种皮肤细胞修复具持续作用的人血清白蛋白重组融合蛋白 |
| KR101634664B1 (ko) * | 2007-08-29 | 2016-06-29 | 에텍스 코포레이션 | 골 시멘트 혼합 및 전달 시스템 및 그의 사용 방법 |
| CA2715254A1 (en) * | 2008-02-07 | 2009-08-13 | Biomimetic Therapeutics, Inc. | Compositions and methods for distraction osteogenesis |
| JP2012519556A (ja) * | 2009-03-05 | 2012-08-30 | バイオミメティック セラピューティクス， インコーポレイテッド | 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法 |
-
2011
- 2011-12-13 WO PCT/US2011/064698 patent/WO2012082773A1/en not_active Ceased
- 2011-12-13 MX MX2013006697A patent/MX362405B/es active IP Right Grant
- 2011-12-13 KR KR1020137015102A patent/KR20140038348A/ko not_active Ceased
- 2011-12-13 US US13/992,033 patent/US20140308332A1/en not_active Abandoned
- 2011-12-13 CN CN201180067451.1A patent/CN103491888A/zh active Pending
- 2011-12-13 CN CN201810399549.0A patent/CN108498873A/zh active Pending
- 2011-12-13 EP EP11848160.5A patent/EP2651319A4/en not_active Withdrawn
- 2011-12-13 CA CA2819258A patent/CA2819258C/en active Active
- 2011-12-13 KR KR1020187031242A patent/KR20180121674A/ko not_active Ceased
- 2011-12-13 BR BR112013014686A patent/BR112013014686A2/pt not_active IP Right Cessation
- 2011-12-13 AU AU2011343995A patent/AU2011343995A1/en not_active Abandoned
- 2011-12-13 KR KR1020207013423A patent/KR20200055149A/ko not_active Ceased
- 2011-12-13 JP JP2013544705A patent/JP6116484B2/ja not_active Expired - Fee Related
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2016
- 2016-10-28 JP JP2016211737A patent/JP2017018710A/ja active Pending
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2018
- 2018-05-08 US US15/973,903 patent/US20190365946A1/en not_active Abandoned
- 2018-07-26 JP JP2018139921A patent/JP2018161541A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP6116484B2 (ja) | 2017-04-19 |
| AU2011343995A1 (en) | 2013-06-20 |
| BR112013014686A2 (pt) | 2016-10-04 |
| KR20180121674A (ko) | 2018-11-07 |
| CN108498873A (zh) | 2018-09-07 |
| JP2017018710A (ja) | 2017-01-26 |
| KR20200055149A (ko) | 2020-05-20 |
| WO2012082773A1 (en) | 2012-06-21 |
| EP2651319A1 (en) | 2013-10-23 |
| US20140308332A1 (en) | 2014-10-16 |
| JP2018161541A (ja) | 2018-10-18 |
| MX362405B (es) | 2019-01-15 |
| MX2013006697A (es) | 2013-10-30 |
| CN103491888A (zh) | 2014-01-01 |
| KR20140038348A (ko) | 2014-03-28 |
| EP2651319A4 (en) | 2016-08-17 |
| US20190365946A1 (en) | 2019-12-05 |
| JP2013545584A (ja) | 2013-12-26 |
| CA2819258A1 (en) | 2012-06-21 |
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