JP2013543841A5 - - Google Patents
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- Publication number
- JP2013543841A5 JP2013543841A5 JP2013534441A JP2013534441A JP2013543841A5 JP 2013543841 A5 JP2013543841 A5 JP 2013543841A5 JP 2013534441 A JP2013534441 A JP 2013534441A JP 2013534441 A JP2013534441 A JP 2013534441A JP 2013543841 A5 JP2013543841 A5 JP 2013543841A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- achiral
- cyclohexen
- base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IBPCT/IB2010/054743 | 2010-10-20 | ||
| IB2010054743 | 2010-10-20 | ||
| PCT/IB2011/054666 WO2012052943A1 (en) | 2010-10-20 | 2011-10-19 | Diastereoselective preparation of bicyclo[2.2.2]octan-2-one compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013543841A JP2013543841A (ja) | 2013-12-09 |
| JP2013543841A5 true JP2013543841A5 (enExample) | 2014-12-04 |
| JP5909238B2 JP5909238B2 (ja) | 2016-04-26 |
Family
ID=44906287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013534441A Expired - Fee Related JP5909238B2 (ja) | 2010-10-20 | 2011-10-19 | ビシクロ［２．２．２］オクタン−２−オン化合物のジアステレオ選択的な製造 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8816118B2 (enExample) |
| EP (1) | EP2630120B1 (enExample) |
| JP (1) | JP5909238B2 (enExample) |
| KR (1) | KR101836552B1 (enExample) |
| CN (1) | CN103153947B (enExample) |
| CA (1) | CA2813160C (enExample) |
| DK (1) | DK2630120T3 (enExample) |
| ES (1) | ES2692656T3 (enExample) |
| IL (1) | IL225764A (enExample) |
| MX (1) | MX2013004425A (enExample) |
| WO (1) | WO2012052943A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012052939A2 (en) | 2010-10-20 | 2012-04-26 | Actelion Pharmaceuticals Ltd | Preparation of bicyclo[2.2.2]octan-2-one compounds |
| CN103570513A (zh) * | 2012-08-07 | 2014-02-12 | 中国科学院大连化学物理研究所 | 一种手性双环[n.3.1]化合物的催化不对称合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2008001205A1 (es) | 2007-04-27 | 2008-11-14 | Actelion Pharmaceuticals Ltd | Compuestos derivados de biciclo[2.2.2]octeno; composicion farmaceutica que los contiene; y uso en el tratamiento o prevencion de angina cronica estable, hipertension, isquemia renal y cardiaca, arritmias cardiacas, hipertrofia cardiaca y falla congestiva del corazon. |
| AU2009239620A1 (en) | 2008-04-25 | 2009-10-29 | Actelion Pharmaceuticals Ltd | Benzimidazole derivatives as calcium channel blockers |
| EP2344461B1 (en) * | 2008-10-22 | 2016-12-14 | Actelion Pharmaceuticals Ltd. | Salts of isobutyric acid (1r*,2r*,4r*)-2-(2-{[3-(4,7-dimethoxy-1 h-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-5-phenyl-bicyclo[2.2.2]oct-5-en-2-yl ester |
| WO2012052939A2 (en) | 2010-10-20 | 2012-04-26 | Actelion Pharmaceuticals Ltd | Preparation of bicyclo[2.2.2]octan-2-one compounds |
-
2011
- 2011-10-19 DK DK11778981.8T patent/DK2630120T3/en active
- 2011-10-19 JP JP2013534441A patent/JP5909238B2/ja not_active Expired - Fee Related
- 2011-10-19 WO PCT/IB2011/054666 patent/WO2012052943A1/en not_active Ceased
- 2011-10-19 MX MX2013004425A patent/MX2013004425A/es active IP Right Grant
- 2011-10-19 ES ES11778981.8T patent/ES2692656T3/es active Active
- 2011-10-19 EP EP11778981.8A patent/EP2630120B1/en active Active
- 2011-10-19 CN CN201180047343.8A patent/CN103153947B/zh not_active Expired - Fee Related
- 2011-10-19 KR KR1020137012607A patent/KR101836552B1/ko not_active Expired - Fee Related
- 2011-10-19 CA CA2813160A patent/CA2813160C/en active Active
- 2011-10-19 US US13/880,486 patent/US8816118B2/en active Active
-
2013
- 2013-04-15 IL IL225764A patent/IL225764A/en active IP Right Grant
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