JP2013543499A5 - - Google Patents
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- Publication number
- JP2013543499A5 JP2013543499A5 JP2013531966A JP2013531966A JP2013543499A5 JP 2013543499 A5 JP2013543499 A5 JP 2013543499A5 JP 2013531966 A JP2013531966 A JP 2013531966A JP 2013531966 A JP2013531966 A JP 2013531966A JP 2013543499 A5 JP2013543499 A5 JP 2013543499A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- amino acid
- polypeptide
- residues
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 10
- 102000004196 processed proteins & peptides Human genes 0.000 claims 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 239000011230 binding agent Substances 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 240000008042 Zea mays Species 0.000 claims 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims 1
- 210000000621 bronchi Anatomy 0.000 claims 1
- 235000005822 corn Nutrition 0.000 claims 1
- 210000002919 epithelial cell Anatomy 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000000241 respiratory effect Effects 0.000 claims 1
- 210000003437 trachea Anatomy 0.000 claims 1
- 241000712461 unidentified influenza virus Species 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38963910P | 2010-10-04 | 2010-10-04 | |
| US61/389,639 | 2010-10-04 | ||
| PCT/US2011/054831 WO2012047941A2 (en) | 2010-10-04 | 2011-10-04 | Hemagglutinin polypeptides, and reagents and methods relating thereto |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016030091A Division JP6143902B2 (ja) | 2010-10-04 | 2016-02-19 | 血球凝集素ポリペプチド、ならびにそれに関連する試薬および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013543499A JP2013543499A (ja) | 2013-12-05 |
| JP2013543499A5 true JP2013543499A5 (enExample) | 2014-11-20 |
| JP6029586B2 JP6029586B2 (ja) | 2016-11-24 |
Family
ID=44860519
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013531966A Active JP6029586B2 (ja) | 2010-10-04 | 2011-10-04 | 血球凝集素ポリペプチド、ならびにそれに関連する試薬および方法 |
| JP2016030091A Active JP6143902B2 (ja) | 2010-10-04 | 2016-02-19 | 血球凝集素ポリペプチド、ならびにそれに関連する試薬および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016030091A Active JP6143902B2 (ja) | 2010-10-04 | 2016-02-19 | 血球凝集素ポリペプチド、ならびにそれに関連する試薬および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10226527B2 (enExample) |
| EP (1) | EP2624864B1 (enExample) |
| JP (2) | JP6029586B2 (enExample) |
| CN (1) | CN103328002B (enExample) |
| AU (1) | AU2011312178B2 (enExample) |
| BR (1) | BR112013007946B1 (enExample) |
| CA (1) | CA2813078A1 (enExample) |
| RU (1) | RU2663718C2 (enExample) |
| SG (2) | SG10201709806VA (enExample) |
| WO (1) | WO2012047941A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201709806VA (en) | 2010-10-04 | 2017-12-28 | Massachusetts Inst Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
| AR083533A1 (es) * | 2010-10-22 | 2013-03-06 | Boehringer Ingelheim Vetmed | Proteinas de hemaglutinina 5 (h5) para el tratamiento y prevencion de las infecciones de gripe |
| CN116218900A (zh) | 2011-09-30 | 2023-06-06 | 麦迪卡格公司 | 增加植物中病毒样颗粒的产率 |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| WO2013169377A1 (en) * | 2012-05-10 | 2013-11-14 | Massachusetts Institute Of Technology | Agents for influenza neutralization |
| US9969794B2 (en) | 2012-05-10 | 2018-05-15 | Visterra, Inc. | HA binding agents |
| EP2953967B1 (en) * | 2013-02-07 | 2019-05-01 | Massachusetts Institute of Technology | Human adaptation of h5 influenza |
| HK1216723A1 (zh) | 2013-03-15 | 2016-12-02 | The Trustees Of The University Of Pennsylvania | 流感核酸分子和由其製備的疫苗 |
| EP2978848B1 (en) * | 2013-03-28 | 2020-05-06 | Medicago Inc. | Influenza virus-like particle production in plants |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| US11441150B2 (en) | 2014-01-10 | 2022-09-13 | Medicago Inc. | CPMV enhancer elements |
| WO2016100926A1 (en) * | 2014-12-19 | 2016-06-23 | Oregon Health & Science University | Synergistic co-administration of computationally optimized broadly reactive antigens for human and avian h5n1 influenza |
| WO2017083627A1 (en) | 2015-11-13 | 2017-05-18 | Visterra, Inc. | Compositions and methods for treating and preventing influenza |
| EP3419663A1 (en) | 2016-02-24 | 2019-01-02 | Visterra, Inc. | Formulations of antibody molecules to influenza virus |
| WO2019086463A1 (en) | 2017-10-30 | 2019-05-09 | Baxalta GmbH | Environmentally compatible detergents for inactivation of lipid-enveloped viruses |
| CN113924147A (zh) | 2019-03-25 | 2022-01-11 | 威特拉公司 | 用于治疗和预防流感的组合物和方法 |
| CN110172452B (zh) * | 2019-05-21 | 2021-07-06 | 广州医科大学 | 一种高致病性h7n9禽流感病毒、疫苗、检测试剂以及病毒、疫苗的制备方法 |
| JP2022038604A (ja) | 2020-08-27 | 2022-03-10 | 株式会社Subaru | 車両の制御装置 |
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| BRPI0111830B8 (pt) | 2000-06-23 | 2021-05-25 | American Cyanamid Co | método de produção de partículas semelhantes ao vírus da influenza (vlps), vlps da influenza, vlps quiméricas, composições imunogênica e farmacêutica, e, usos de vlps da influenza e de vlps quiméricas |
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| CN102165062B (zh) | 2008-07-18 | 2017-09-08 | 麦迪卡格公司 | 新的流感病毒免疫表位 |
| WO2011003100A2 (en) | 2009-07-02 | 2011-01-06 | Massachusetts Institute Of Technology | Compositions and methods for diagnosing and/or treating influenza infection |
| SG10201709806VA (en) | 2010-10-04 | 2017-12-28 | Massachusetts Inst Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
| EP2953967B1 (en) | 2013-02-07 | 2019-05-01 | Massachusetts Institute of Technology | Human adaptation of h5 influenza |
-
2011
- 2011-10-04 SG SG10201709806VA patent/SG10201709806VA/en unknown
- 2011-10-04 CN CN201180057213.2A patent/CN103328002B/zh active Active
- 2011-10-04 SG SG2013024617A patent/SG189236A1/en unknown
- 2011-10-04 EP EP11774134.8A patent/EP2624864B1/en active Active
- 2011-10-04 WO PCT/US2011/054831 patent/WO2012047941A2/en not_active Ceased
- 2011-10-04 AU AU2011312178A patent/AU2011312178B2/en active Active
- 2011-10-04 RU RU2013114424A patent/RU2663718C2/ru active
- 2011-10-04 JP JP2013531966A patent/JP6029586B2/ja active Active
- 2011-10-04 CA CA2813078A patent/CA2813078A1/en active Pending
- 2011-10-04 BR BR112013007946-0A patent/BR112013007946B1/pt active IP Right Grant
- 2011-10-04 US US13/253,060 patent/US10226527B2/en active Active
-
2016
- 2016-02-19 JP JP2016030091A patent/JP6143902B2/ja active Active
-
2019
- 2019-01-17 US US16/250,920 patent/US20190142931A1/en not_active Abandoned
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