CN103328002B - 血球凝集素多肽以及与其相关的试剂和方法 - Google Patents

血球凝集素多肽以及与其相关的试剂和方法 Download PDF

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CN103328002B
CN103328002B CN201180057213.2A CN201180057213A CN103328002B CN 103328002 B CN103328002 B CN 103328002B CN 201180057213 A CN201180057213 A CN 201180057213A CN 103328002 B CN103328002 B CN 103328002B
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polypeptide
glycans
binding
polypeptides
glycan
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CN103328002A (zh
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卡纳安·塔拉卡拉曼
卡西克·维斯瓦那坦
拉胡尔·拉曼
拉姆·萨西谢卡尔安
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MIT
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
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  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201180057213.2A 2010-10-04 2011-10-04 血球凝集素多肽以及与其相关的试剂和方法 Active CN103328002B (zh)

Applications Claiming Priority (3)

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US38963910P 2010-10-04 2010-10-04
US61/389,639 2010-10-04
PCT/US2011/054831 WO2012047941A2 (en) 2010-10-04 2011-10-04 Hemagglutinin polypeptides, and reagents and methods relating thereto

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CN103328002A CN103328002A (zh) 2013-09-25
CN103328002B true CN103328002B (zh) 2020-01-14

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EP (1) EP2624864B1 (enExample)
JP (2) JP6029586B2 (enExample)
CN (1) CN103328002B (enExample)
AU (1) AU2011312178B2 (enExample)
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CA (1) CA2813078A1 (enExample)
RU (1) RU2663718C2 (enExample)
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US11390878B2 (en) 2011-09-30 2022-07-19 Medicago Inc. Increasing protein yield in plants
CN116218900A (zh) 2011-09-30 2023-06-06 麦迪卡格公司 增加植物中病毒样颗粒的产率
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US12467058B2 (en) * 2013-03-28 2025-11-11 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
EP3092309B1 (en) 2014-01-10 2021-02-24 Medicago Inc. Cpmv enhancer elements
CN107847579A (zh) * 2014-12-19 2018-03-27 俄勒冈健康与科学大学 人和禽h5n1流感的计算优化的广泛反应性抗原的协同共同给药
US10513553B2 (en) 2015-11-13 2019-12-24 Visterra, Inc. Compositions and methods for treating and preventing influenza
CA3015347A1 (en) 2016-02-24 2017-08-31 Visterra, Inc. Formulations of antibody molecules to influenza virus
ES2991988T3 (es) 2017-10-30 2024-12-05 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivación de virus con envoltura lipídica
JP2022521819A (ja) 2019-03-25 2022-04-12 ビステラ， インコーポレイテッド インフルエンザを処置および予防するための組成物および方法
CN110172452B (zh) * 2019-05-21 2021-07-06 广州医科大学 一种高致病性h7n9禽流感病毒、疫苗、检测试剂以及病毒、疫苗的制备方法
JP2022038604A (ja) 2020-08-27 2022-03-10 株式会社Subaru 車両の制御装置

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SG189236A1 (en) 2013-05-31
JP6029586B2 (ja) 2016-11-24
JP6143902B2 (ja) 2017-06-07
EP2624864A2 (en) 2013-08-14
US20190142931A1 (en) 2019-05-16
BR112013007946A2 (pt) 2018-04-17
EP2624864B1 (en) 2017-12-06
US10226527B2 (en) 2019-03-12
US20120213819A1 (en) 2012-08-23
AU2011312178A1 (en) 2013-05-02
JP2013543499A (ja) 2013-12-05
SG10201709806VA (en) 2017-12-28
WO2012047941A2 (en) 2012-04-12
RU2663718C2 (ru) 2018-08-08
CA2813078A1 (en) 2012-04-12
WO2012047941A3 (en) 2013-04-11
CN103328002A (zh) 2013-09-25
BR112013007946B1 (pt) 2022-07-12
JP2016094483A (ja) 2016-05-26
RU2013114424A (ru) 2014-11-20
AU2011312178B2 (en) 2016-05-12

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