JP2013540714A5 - - Google Patents

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Publication number
JP2013540714A5
JP2013540714A5 JP2013526503A JP2013526503A JP2013540714A5 JP 2013540714 A5 JP2013540714 A5 JP 2013540714A5 JP 2013526503 A JP2013526503 A JP 2013526503A JP 2013526503 A JP2013526503 A JP 2013526503A JP 2013540714 A5 JP2013540714 A5 JP 2013540714A5
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JP
Japan
Prior art keywords
alkyl
group
heterocyclyl
carbocyclyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2013526503A
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English (en)
Japanese (ja)
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JP5928737B2 (ja
JP2013540714A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2011/065332 external-priority patent/WO2012032014A1/en
Publication of JP2013540714A publication Critical patent/JP2013540714A/ja
Publication of JP2013540714A5 publication Critical patent/JP2013540714A5/ja
Application granted granted Critical
Publication of JP5928737B2 publication Critical patent/JP5928737B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013526503A 2010-09-06 2011-09-05 エチン誘導体、医薬組成物及びその使用 Expired - Fee Related JP5928737B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10175456 2010-09-06
EP10175456.2 2010-09-06
PCT/EP2011/065332 WO2012032014A1 (en) 2010-09-06 2011-09-05 Ethyne derivatives, pharmaceutical compositions and uses thereof

Publications (3)

Publication Number Publication Date
JP2013540714A JP2013540714A (ja) 2013-11-07
JP2013540714A5 true JP2013540714A5 (enExample) 2014-10-23
JP5928737B2 JP5928737B2 (ja) 2016-06-01

Family

ID=44584179

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013526503A Expired - Fee Related JP5928737B2 (ja) 2010-09-06 2011-09-05 エチン誘導体、医薬組成物及びその使用

Country Status (4)

Country Link
US (1) US8877754B2 (enExample)
EP (1) EP2614054B1 (enExample)
JP (1) JP5928737B2 (enExample)
WO (1) WO2012032014A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2997024B1 (en) * 2013-05-17 2018-03-28 Boehringer Ingelheim International GmbH Pyrrolidine derivatives, pharmaceutical compositions and uses thereof
BR112016004118A2 (pt) 2013-09-12 2017-10-17 Pfizer uso de inibidores da acetil-coa carboxilase para tratamento de acne vulgar
EP2924027A1 (en) * 2014-03-28 2015-09-30 Basf Se Substituted [1,2,4]triazole and imidazole fungicidal compounds
HRP20192009T1 (hr) 2014-12-16 2020-02-07 Novartis Ag Spojevi izoksazol hidroksamske kiseline kao inhibitori lpxc-a
EP3400220B1 (en) * 2016-01-05 2021-03-24 Hua Medicine (Shanghai) Ltd. Pyrazole derivatives
SG11201810656WA (en) 2016-06-14 2018-12-28 Novartis Ag Crystalline form of (r)-4-(5-(cyclopropylethynyl)isoxazol-3-yl)-n-hydroxy-2-methyl-2-(methylsulfonyl)butanamide as an antibacterial agent
CN119930483A (zh) * 2018-08-24 2025-05-06 赛尼欧普罗有限责任公司 用于治疗病态状况的芳香型分子

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042584A (en) * 1974-08-19 1977-08-16 Merck & Co., Inc. Ethynylaryl phenyl cyclopropyl thiazines and morpholines
HUT73813A (en) * 1993-06-30 1996-09-30 Wellcome Found Anti-athero-sclerotic diaryl compounds, process to prepare them and pharmaceutical compositions contg. them
PT1282612E (pt) * 2000-05-03 2005-04-29 Hoffmann La Roche Actividades heteroaromaticas da glucoquinase a vase de alcinilo-fenilo
KR20030030029A (ko) * 2000-09-22 2003-04-16 니혼노야쿠가부시키가이샤 Ｎ-(4-피라졸릴)아미드 유도체 및 농원예용 약제 그리고그 사용방법
DE10219294A1 (de) * 2002-04-25 2003-11-13 Schering Ag Substituierte N-(1,4,5,6-Tetrahydro-cyclopentapyrazol-3-yl)-Derivate, deren Herstellung und Verwendung als Arzneimittel
US7524862B2 (en) 2004-04-14 2009-04-28 Boehringer Ingelheim International Gmbh Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
WO2008002671A2 (en) 2006-06-29 2008-01-03 Alantos Pharmaceuticals Holding, Inc. Metalloprotease inhibitors
CN101918079A (zh) 2008-01-22 2010-12-15 默克专利有限公司 蛋白激酶抑制剂及其用途
JP5535931B2 (ja) 2008-10-27 2014-07-02 武田薬品工業株式会社 二環性化合物

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