JP2011006409A5 - - Google Patents
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- Publication number
- JP2011006409A5 JP2011006409A5 JP2010123614A JP2010123614A JP2011006409A5 JP 2011006409 A5 JP2011006409 A5 JP 2011006409A5 JP 2010123614 A JP2010123614 A JP 2010123614A JP 2010123614 A JP2010123614 A JP 2010123614A JP 2011006409 A5 JP2011006409 A5 JP 2011006409A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- optionally substituted
- substituted
- halogen atom
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 125000005843 halogen group Chemical group 0.000 claims 21
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 17
- 125000001424 substituent group Chemical group 0.000 claims 15
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 14
- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims 11
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 10
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 9
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 229910052757 nitrogen Inorganic materials 0.000 claims 5
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 4
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 4
- 125000003277 amino group Chemical group 0.000 claims 4
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 claims 4
- 125000004104 aryloxy group Chemical group 0.000 claims 4
- 125000004093 cyano group Chemical group *C#N 0.000 claims 4
- 229910052736 halogen Inorganic materials 0.000 claims 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 4
- 229910052760 oxygen Inorganic materials 0.000 claims 4
- 230000001225 therapeutic effect Effects 0.000 claims 4
- 125000005915 C6-C14 aryl group Chemical group 0.000 claims 3
- 108010025020 Nerve Growth Factor Proteins 0.000 claims 3
- 102000007072 Nerve Growth Factors Human genes 0.000 claims 3
- 125000004432 carbon atom Chemical group C* 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 239000003900 neurotrophic factor Substances 0.000 claims 3
- 238000000554 physical therapy Methods 0.000 claims 3
- 208000032131 Diabetic Neuropathies Diseases 0.000 claims 2
- 125000002015 acyclic group Chemical group 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 2
- 125000003368 amide group Chemical group 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 230000002490 cerebral effect Effects 0.000 claims 2
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 125000004185 ester group Chemical group 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 2
- 208000023589 ischemic disease Diseases 0.000 claims 2
- 125000004043 oxo group Chemical group O=* 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000003449 preventive effect Effects 0.000 claims 2
- 230000000069 prophylactic effect Effects 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000012453 solvate Substances 0.000 claims 2
- 125000005750 substituted cyclic group Chemical group 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 150000004945 aromatic hydrocarbons Chemical group 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010123614A JP2011006409A (ja) | 2009-05-29 | 2010-05-28 | 神経栄養因子の活性が関与する疾患の治療または予防剤 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009131333 | 2009-05-29 | ||
| JP2010123614A JP2011006409A (ja) | 2009-05-29 | 2010-05-28 | 神経栄養因子の活性が関与する疾患の治療または予防剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011006409A JP2011006409A (ja) | 2011-01-13 |
| JP2011006409A5 true JP2011006409A5 (enExample) | 2013-06-06 |
Family
ID=43222475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010123614A Ceased JP2011006409A (ja) | 2009-05-29 | 2010-05-28 | 神経栄養因子の活性が関与する疾患の治療または予防剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8829035B2 (enExample) |
| EP (1) | EP2436683B1 (enExample) |
| JP (1) | JP2011006409A (enExample) |
| KR (1) | KR20120093066A (enExample) |
| CN (1) | CN102428080A (enExample) |
| AU (1) | AU2010253336A1 (enExample) |
| BR (1) | BRPI1011961A2 (enExample) |
| CA (1) | CA2762620A1 (enExample) |
| ES (1) | ES2484169T3 (enExample) |
| MX (1) | MX2011012537A (enExample) |
| WO (1) | WO2010137349A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016511237A (ja) * | 2013-02-01 | 2016-04-14 | アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 選択的ｈｄａｃ３阻害剤 |
| TWI637943B (zh) * | 2013-09-05 | 2018-10-11 | 田邊三菱製藥股份有限公司 | 新穎結晶性芳烷基胺化合物及其製造方法 |
| US10035777B2 (en) * | 2014-08-05 | 2018-07-31 | Bristol-Myers Squibb Company | Heterocyclic kinase inhibitors |
| US10556884B2 (en) | 2015-09-28 | 2020-02-11 | Syngenta Participations Ag | Pesticidally active heterocyclic derivatives with sulphur containing substituents |
| CN108299413A (zh) * | 2018-01-22 | 2018-07-20 | 复旦大学 | 一种无金属催化制备2-(胺基苯基)苯并噁唑及其衍生物的方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1063028B (de) * | 1957-09-10 | 1959-08-06 | Wolfen Filmfab Veb | Verfahren zur Sensibilisierung von Halogensilberemulsionen |
| DE4023369A1 (de) | 1990-07-23 | 1992-01-30 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| RU1836357C (ru) | 1990-07-23 | 1993-08-23 | Др.Карл Томэ ГмбХ | Производные бензимидазола, их изомеры, смеси изомеров, гидраты или их физиологически переносимые соли, обладающие антагонистическими в отношении ангиотензина свойствами |
| JPH04308580A (ja) | 1991-04-05 | 1992-10-30 | Sumitomo Chem Co Ltd | ベンズイミダゾール誘導体、その製造法およびそれを有効成分とする農園芸用殺菌剤 |
| GB9418326D0 (en) | 1994-09-12 | 1994-11-02 | Lilly Industries Ltd | Pharmaceutical compounds |
| ES2204932T3 (es) | 1994-09-12 | 2004-05-01 | Eli Lilly And Company Limited | Moduladores serotonergicos. |
| MXPA01011283A (es) | 1999-05-03 | 2002-11-04 | Battelle Memorial Institute | Composiciones par aerosolizacion e inhalacion. |
| DE19920936A1 (de) * | 1999-05-07 | 2000-11-09 | Basf Ag | Heterozyklisch substituierte Benzimidazole, deren Herstellung und Anwendung |
| EP1206265B1 (en) * | 1999-06-30 | 2003-11-12 | Merck & Co., Inc. | Src kinase inhibitor compounds |
| US6919331B2 (en) | 2001-12-10 | 2005-07-19 | Bristol-Myers Squibb Company | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents |
| CN1623992A (zh) * | 2003-12-03 | 2005-06-08 | 北京师范大学 | 新型非肽类血管紧张素ⅱ受体拮抗剂类药物、它们的制备及应用 |
| US20070249599A1 (en) | 2004-02-25 | 2007-10-25 | Duffy Kevin J | Novel Chemical Compounds |
| JP2007282501A (ja) | 2006-03-24 | 2007-11-01 | Sumitomo Chemical Co Ltd | アポトーシス制御能力の検定方法 |
| JP2007282502A (ja) | 2006-03-24 | 2007-11-01 | Sumitomo Chemical Co Ltd | 細胞変性制御能力の検定方法 |
| CA2652307A1 (en) | 2006-04-10 | 2007-10-18 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| WO2008073451A2 (en) * | 2006-12-11 | 2008-06-19 | Sirtris Pharmaceuticals, Inc. | Benzoimidazole derivatives as sirtuin (sir) modulating compounds |
| WO2008153701A1 (en) * | 2007-05-24 | 2008-12-18 | Schering Corporation | Compounds for inhibiting ksp kinesin activity |
| US8084466B2 (en) * | 2007-12-18 | 2011-12-27 | Janssen Pharmaceutica Nv | Bicyclic heteroaryl-substituted imidazoles as modulators of the histamine H4 receptor |
| JP2010047517A (ja) * | 2008-08-21 | 2010-03-04 | Sumitomo Chemical Co Ltd | 神経栄養因子の活性が関与する疾患の治療または予防剤、およびその製造方法 |
-
2010
- 2010-05-28 CA CA2762620A patent/CA2762620A1/en not_active Abandoned
- 2010-05-28 KR KR1020117031347A patent/KR20120093066A/ko not_active Withdrawn
- 2010-05-28 CN CN2010800218228A patent/CN102428080A/zh active Pending
- 2010-05-28 BR BRPI1011961A patent/BRPI1011961A2/pt not_active IP Right Cessation
- 2010-05-28 MX MX2011012537A patent/MX2011012537A/es not_active Application Discontinuation
- 2010-05-28 ES ES10780309.0T patent/ES2484169T3/es active Active
- 2010-05-28 JP JP2010123614A patent/JP2011006409A/ja not_active Ceased
- 2010-05-28 WO PCT/JP2010/003622 patent/WO2010137349A1/ja not_active Ceased
- 2010-05-28 EP EP10780309.0A patent/EP2436683B1/en active Active
- 2010-05-28 US US13/322,888 patent/US8829035B2/en not_active Expired - Fee Related
- 2010-05-28 AU AU2010253336A patent/AU2010253336A1/en not_active Abandoned
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