JP2013539765A5 - - Google Patents
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- Publication number
- JP2013539765A5 JP2013539765A5 JP2013532985A JP2013532985A JP2013539765A5 JP 2013539765 A5 JP2013539765 A5 JP 2013539765A5 JP 2013532985 A JP2013532985 A JP 2013532985A JP 2013532985 A JP2013532985 A JP 2013532985A JP 2013539765 A5 JP2013539765 A5 JP 2013539765A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- heterocyclyl
- heteroaryl
- mmol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39142310P | 2010-10-08 | 2010-10-08 | |
| US61/391,423 | 2010-10-08 | ||
| PCT/US2011/055428 WO2012048259A2 (en) | 2010-10-08 | 2011-10-07 | Substituted pyridazine carboxamide compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016124463A Division JP6235078B2 (ja) | 2010-10-08 | 2016-06-23 | 置換ピリダジンカルボキサミド化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013539765A JP2013539765A (ja) | 2013-10-28 |
| JP2013539765A5 true JP2013539765A5 (https=) | 2016-09-01 |
| JP6023062B2 JP6023062B2 (ja) | 2016-11-09 |
Family
ID=45928473
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532985A Active JP6023062B2 (ja) | 2010-10-08 | 2011-10-07 | 置換ピリダジンカルボキサミド化合物 |
| JP2016124463A Active JP6235078B2 (ja) | 2010-10-08 | 2016-06-23 | 置換ピリダジンカルボキサミド化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016124463A Active JP6235078B2 (ja) | 2010-10-08 | 2016-06-23 | 置換ピリダジンカルボキサミド化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9126947B2 (https=) |
| EP (1) | EP2625176B1 (https=) |
| JP (2) | JP6023062B2 (https=) |
| KR (1) | KR101886812B1 (https=) |
| CN (1) | CN103298806B (https=) |
| AU (1) | AU2011311814B2 (https=) |
| BR (1) | BR112013008523B1 (https=) |
| CA (1) | CA2813607C (https=) |
| EA (1) | EA024809B1 (https=) |
| ES (1) | ES2610226T3 (https=) |
| PL (1) | PL2625176T3 (https=) |
| WO (1) | WO2012048259A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2550264B1 (en) * | 2010-03-23 | 2016-06-08 | Basf Se | Pyridazine compounds for controlling invertebrate pests |
| EA024809B1 (ru) * | 2010-10-08 | 2016-10-31 | Икскавери Холдинг Кампани, Ллс | Замещенные соединения пиридазинкарбоксамида |
| JP6013029B2 (ja) * | 2012-05-25 | 2016-10-25 | 千葉県 | 抗癌剤 |
| RU2550346C2 (ru) * | 2013-09-26 | 2015-05-10 | Общество с ограниченной ответственностью "Отечественные Фармацевтические Технологии" ООО"ФармТех" | Новые химические соединения (варианты) и их применение для лечения онкологических заболеваний |
| CN105085550B (zh) * | 2014-05-21 | 2017-05-24 | 海门慧聚药业有限公司 | 一类alk激酶抑制剂及其制备方法 |
| RU2015110071A (ru) * | 2015-03-23 | 2016-10-10 | Общество с ограниченной ответственностью "Отечественные Фармацевтические Технологии" ООО "ФармТех" | Применение новых химических соединений (варианты) в качестве ингибиторов nuak1 киназы для лечения онкологических заболеваний |
| TWI646094B (zh) | 2016-06-01 | 2019-01-01 | 大陸商貝達藥業股份有限公司 | Crystal form of inhibitory protein kinase active compound and application thereof |
| RU2631430C1 (ru) * | 2016-10-26 | 2017-09-22 | Общество С Ограниченной Ответственностью "Отечественные Фармацевтические Технологии" | НОВЫЙ СПОСОБ СИНТЕЗА ПРОИЗВОДНЫХ ТЕТРАГИДРОПИРАЗИНО[2,3-c]ПИРИДАЗИНА |
| CN110357889B (zh) * | 2018-04-09 | 2022-03-15 | 上海科技大学 | 蛋白降解靶向化合物、其抗肿瘤应用、其中间体及中间体应用 |
| EP3932922A4 (en) | 2019-02-25 | 2022-05-11 | ShanghaiTech University | SULPHUR-CONTAINING COMPOUND BASED ON A GLUTARIMIDE FRAMEWORK AND ITS USE |
| WO2021023233A1 (zh) | 2019-08-05 | 2021-02-11 | 上海科技大学 | Egfr蛋白降解剂及其抗肿瘤应用 |
| EP4188922A1 (en) | 2020-08-03 | 2023-06-07 | Teva Pharmaceuticals International GmbH | Solid state forms of ensartinib and ensartinib salts |
| EP4385510A4 (en) * | 2021-08-10 | 2025-08-20 | Betta Pharmaceuticals Co Ltd | USE OF ENSARTINIB OR A CORRESPONDING SALT IN THE TREATMENT OF A DISEASE CARRYING A MET EXON 14 SKIPPING MUTATION |
| CN116082110B (zh) * | 2023-01-09 | 2024-04-12 | 北京肿瘤医院(北京大学肿瘤医院) | 一种11c标记靶向间变性淋巴瘤激酶alk突变分子探针及应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4369172A (en) | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
| DE3583799D1 (de) | 1985-01-11 | 1991-09-19 | Abbott Lab Ltd | Feste zubereitung mit langsamer freisetzung. |
| JP2773959B2 (ja) | 1990-07-10 | 1998-07-09 | 信越化学工業株式会社 | 大腸内放出性固形製剤 |
| UA73092C2 (uk) | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
| DE69924735T2 (de) | 1998-07-28 | 2006-01-19 | Tanabe Seiyaku Co., Ltd. | Zur wirkstoffabgabe an zielorten im darm fähige zubereitung |
| US6461631B1 (en) | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US6800663B2 (en) | 2002-10-18 | 2004-10-05 | Alkermes Controlled Therapeutics Inc. Ii, | Crosslinked hydrogel copolymers |
| CA2517256C (en) | 2003-02-26 | 2013-04-30 | Sugen, Inc. | Aminoheteroaryl compounds as protein kinase inhibitors |
| BRPI0514687A (pt) * | 2004-08-26 | 2008-06-17 | Pfizer | compostos amino heteroarila como inibidores de proteìna tirosina cinase |
| ME01309B (me) | 2004-08-26 | 2013-12-20 | Pfizer | Pirazolom supstituirani heteroarilni spojevi kao inhibitori proteinskih kinaza |
| WO2008088881A1 (en) | 2007-01-19 | 2008-07-24 | Xcovery, Inc. | Kinase inhibitor compounds |
| ES2670665T3 (es) * | 2008-06-19 | 2018-05-31 | Xcovery Holding Company Llc | Compuestos de piridazina carboxamida sustituidos como compuestos inhibidores de quinasa |
| EA024809B1 (ru) * | 2010-10-08 | 2016-10-31 | Икскавери Холдинг Кампани, Ллс | Замещенные соединения пиридазинкарбоксамида |
| WO2012048258A2 (en) * | 2010-10-08 | 2012-04-12 | Xcovery Holding Company, Llc | Substituted pyridazine carboxamide compounds as kinase inhibitor compounds |
-
2011
- 2011-10-07 EA EA201390520A patent/EA024809B1/ru unknown
- 2011-10-07 PL PL11831702T patent/PL2625176T3/pl unknown
- 2011-10-07 KR KR1020137011872A patent/KR101886812B1/ko active Active
- 2011-10-07 CN CN201180057513.0A patent/CN103298806B/zh active Active
- 2011-10-07 AU AU2011311814A patent/AU2011311814B2/en active Active
- 2011-10-07 EP EP11831702.3A patent/EP2625176B1/en active Active
- 2011-10-07 JP JP2013532985A patent/JP6023062B2/ja active Active
- 2011-10-07 US US13/877,783 patent/US9126947B2/en active Active
- 2011-10-07 WO PCT/US2011/055428 patent/WO2012048259A2/en not_active Ceased
- 2011-10-07 BR BR112013008523-1A patent/BR112013008523B1/pt active IP Right Grant
- 2011-10-07 CA CA2813607A patent/CA2813607C/en active Active
- 2011-10-07 ES ES11831702.3T patent/ES2610226T3/es active Active
-
2015
- 2015-09-04 US US14/846,490 patent/US20160068493A1/en not_active Abandoned
-
2016
- 2016-06-23 JP JP2016124463A patent/JP6235078B2/ja active Active
-
2017
- 2017-05-03 US US15/585,961 patent/US20180016240A1/en not_active Abandoned
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