JP2013539765A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013539765A5 JP2013539765A5 JP2013532985A JP2013532985A JP2013539765A5 JP 2013539765 A5 JP2013539765 A5 JP 2013539765A5 JP 2013532985 A JP2013532985 A JP 2013532985A JP 2013532985 A JP2013532985 A JP 2013532985A JP 2013539765 A5 JP2013539765 A5 JP 2013539765A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- heterocyclyl
- heteroaryl
- mmol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39142310P | 2010-10-08 | 2010-10-08 | |
| US61/391,423 | 2010-10-08 | ||
| PCT/US2011/055428 WO2012048259A2 (en) | 2010-10-08 | 2011-10-07 | Substituted pyridazine carboxamide compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016124463A Division JP6235078B2 (ja) | 2010-10-08 | 2016-06-23 | 置換ピリダジンカルボキサミド化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013539765A JP2013539765A (ja) | 2013-10-28 |
| JP2013539765A5 true JP2013539765A5 (enExample) | 2016-09-01 |
| JP6023062B2 JP6023062B2 (ja) | 2016-11-09 |
Family
ID=45928473
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532985A Active JP6023062B2 (ja) | 2010-10-08 | 2011-10-07 | 置換ピリダジンカルボキサミド化合物 |
| JP2016124463A Active JP6235078B2 (ja) | 2010-10-08 | 2016-06-23 | 置換ピリダジンカルボキサミド化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016124463A Active JP6235078B2 (ja) | 2010-10-08 | 2016-06-23 | 置換ピリダジンカルボキサミド化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9126947B2 (enExample) |
| EP (1) | EP2625176B1 (enExample) |
| JP (2) | JP6023062B2 (enExample) |
| KR (1) | KR101886812B1 (enExample) |
| CN (1) | CN103298806B (enExample) |
| AU (1) | AU2011311814B2 (enExample) |
| BR (1) | BR112013008523B1 (enExample) |
| CA (1) | CA2813607C (enExample) |
| EA (1) | EA024809B1 (enExample) |
| ES (1) | ES2610226T3 (enExample) |
| PL (1) | PL2625176T3 (enExample) |
| WO (1) | WO2012048259A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2589792T3 (es) * | 2010-03-23 | 2016-11-16 | Basf Se | Compuestos de piridazina para el control de plagas de invertebrados |
| US9126947B2 (en) * | 2010-10-08 | 2015-09-08 | Xcovery Holding Company Llc | Substituted pyridazine carboxamide compounds |
| JP6013029B2 (ja) * | 2012-05-25 | 2016-10-25 | 千葉県 | 抗癌剤 |
| RU2550346C2 (ru) * | 2013-09-26 | 2015-05-10 | Общество с ограниченной ответственностью "Отечественные Фармацевтические Технологии" ООО"ФармТех" | Новые химические соединения (варианты) и их применение для лечения онкологических заболеваний |
| CN105085550B (zh) * | 2014-05-21 | 2017-05-24 | 海门慧聚药业有限公司 | 一类alk激酶抑制剂及其制备方法 |
| RU2015110071A (ru) * | 2015-03-23 | 2016-10-10 | Общество с ограниченной ответственностью "Отечественные Фармацевтические Технологии" ООО "ФармТех" | Применение новых химических соединений (варианты) в качестве ингибиторов nuak1 киназы для лечения онкологических заболеваний |
| TWI646094B (zh) | 2016-06-01 | 2019-01-01 | 大陸商貝達藥業股份有限公司 | Crystal form of inhibitory protein kinase active compound and application thereof |
| RU2631430C1 (ru) * | 2016-10-26 | 2017-09-22 | Общество С Ограниченной Ответственностью "Отечественные Фармацевтические Технологии" | НОВЫЙ СПОСОБ СИНТЕЗА ПРОИЗВОДНЫХ ТЕТРАГИДРОПИРАЗИНО[2,3-c]ПИРИДАЗИНА |
| US12226424B2 (en) | 2018-04-09 | 2025-02-18 | Shanghaitech University | Target protein degradation compounds, their anti-tumor use, their intermediates and use of intermediates |
| US12582641B2 (en) | 2019-02-25 | 2026-03-24 | Shanghaitech University | Sulfur-containing compound based on glutarimide skeleton and application thereof |
| CN112321566B (zh) | 2019-08-05 | 2022-06-10 | 上海科技大学 | Egfr蛋白降解剂及其抗肿瘤应用 |
| US20230227413A1 (en) | 2020-08-03 | 2023-07-20 | Teva Pharmaceuticals International Gmbh | Solid state forms of ensartinib and ensartinib salts |
| EP4385510A4 (en) * | 2021-08-10 | 2025-08-20 | Betta Pharmaceuticals Co Ltd | USE OF ENSARTINIB OR A CORRESPONDING SALT IN THE TREATMENT OF A DISEASE CARRYING A MET EXON 14 SKIPPING MUTATION |
| CN116082110B (zh) * | 2023-01-09 | 2024-04-12 | 北京肿瘤医院(北京大学肿瘤医院) | 一种11c标记靶向间变性淋巴瘤激酶alk突变分子探针及应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4369172A (en) | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
| ATE66143T1 (de) | 1985-01-11 | 1991-08-15 | Abbott Lab | Feste zubereitung mit langsamer freisetzung. |
| JP2773959B2 (ja) | 1990-07-10 | 1998-07-09 | 信越化学工業株式会社 | 大腸内放出性固形製剤 |
| UA73092C2 (uk) | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
| AU4800999A (en) | 1998-07-28 | 2000-02-21 | Tanabe Seiyaku Co., Ltd. | Preparation capable of releasing drug at target site in intestine |
| US6461631B1 (en) | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US6800663B2 (en) | 2002-10-18 | 2004-10-05 | Alkermes Controlled Therapeutics Inc. Ii, | Crosslinked hydrogel copolymers |
| RS53118B (sr) | 2003-02-26 | 2014-06-30 | Sugen Inc. | Aminoheteroaril jedinjenja kao inhibitori protein kinaze |
| WO2006021886A1 (en) | 2004-08-26 | 2006-03-02 | Pfizer Inc. | Aminoheteroaryl compounds as protein tyrosine kinase inhibitors |
| ATE492544T1 (de) | 2004-08-26 | 2011-01-15 | Pfizer | Pyrazol-substituierte aminoheteroarylverbindungen als proteinkinasehemmer |
| JP2010516680A (ja) * | 2007-01-19 | 2010-05-20 | エックスカバリー，インコーポレイテッド | キナーゼ阻害薬化合物 |
| CA2728408C (en) * | 2008-06-19 | 2017-12-05 | Congxin Liang | Substituted pyridazine carboxamide compounds as kinase inhibitor compounds |
| CN103298803A (zh) * | 2010-10-08 | 2013-09-11 | 艾科睿控股公司 | 作为激酶抑制剂化合物的取代的哒嗪羧酰胺化合物 |
| US9126947B2 (en) * | 2010-10-08 | 2015-09-08 | Xcovery Holding Company Llc | Substituted pyridazine carboxamide compounds |
-
2011
- 2011-10-07 US US13/877,783 patent/US9126947B2/en active Active
- 2011-10-07 WO PCT/US2011/055428 patent/WO2012048259A2/en not_active Ceased
- 2011-10-07 JP JP2013532985A patent/JP6023062B2/ja active Active
- 2011-10-07 PL PL11831702T patent/PL2625176T3/pl unknown
- 2011-10-07 KR KR1020137011872A patent/KR101886812B1/ko active Active
- 2011-10-07 BR BR112013008523-1A patent/BR112013008523B1/pt active IP Right Grant
- 2011-10-07 CN CN201180057513.0A patent/CN103298806B/zh active Active
- 2011-10-07 ES ES11831702.3T patent/ES2610226T3/es active Active
- 2011-10-07 CA CA2813607A patent/CA2813607C/en active Active
- 2011-10-07 AU AU2011311814A patent/AU2011311814B2/en active Active
- 2011-10-07 EA EA201390520A patent/EA024809B1/ru unknown
- 2011-10-07 EP EP11831702.3A patent/EP2625176B1/en active Active
-
2015
- 2015-09-04 US US14/846,490 patent/US20160068493A1/en not_active Abandoned
-
2016
- 2016-06-23 JP JP2016124463A patent/JP6235078B2/ja active Active
-
2017
- 2017-05-03 US US15/585,961 patent/US20180016240A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107771178B (zh) | 杂环化合物的合成 | |
| JP5873554B2 (ja) | キラルジペプチジルペプチダーゼ−ｉｖ阻害剤の調製プロセス | |
| ES2587903T3 (es) | Compuestos de imidazolidinadiona y sus usos | |
| KR101934096B1 (ko) | 이델라리십의 제조방법 | |
| EP3237404A1 (en) | Processes for preparing ask1 inhibitors | |
| CN104507937A (zh) | 吡咯并[2,3-b]吡啶的合成 | |
| JP2013522327A (ja) | ラパチニブの調製プロセス及び中間体 | |
| UA125317C2 (uk) | Удосконалений спосіб отримання похідних амінопіримідину | |
| JP2016531848A (ja) | キナゾリン誘導体およびｄｎａメチルトランスフェラーゼ阻害剤としてのその使用 | |
| JP6901976B2 (ja) | キサンチンをベースとする化合物の調製方法 | |
| CN112585126B (zh) | 四环化合物的制备方法 | |
| KR102477924B1 (ko) | 인돌 카르복스아미드 화합물을 제조하는 방법 | |
| TW201722959A (zh) | 依魯替尼之製備方法及其中間體 | |
| AU2020205355B2 (en) | Chemical process for preparing imidazopyrrolidinone derivatives and intermediates thereof | |
| JP2007522213A (ja) | 置換されたトリアゾール化合物の製造方法 | |
| CN102924454A (zh) | 恩替卡韦的合成方法 | |
| WO2016071382A1 (en) | Synthesis of pi3k inhibitor and salts thereof | |
| Cho et al. | Synthesis and Substitution Reactions of 4 (6)-Chloro-dihydropyrimidines | |
| JP2005112804A (ja) | インドリルメチルアミノピロリジン誘導体およびその製造法 | |
| JP2012521993A (ja) | 縮合三環式スルホンアミドの製造プロセス | |
| HK40037319A (en) | Process for making tricyclic lactam compounds | |
| JP2010540505A (ja) | エピポドフィロトキシンの（ポリ）アミノアルキルアミノアセトアミドの抗腫瘍性誘導体の合成方法 | |
| HK1243069A1 (en) | Process for making tricyclic lactam compounds | |
| WO2016071380A1 (en) | Synthesis of pi3k inhibitor and salts thereof |