JP2013534140A5 - - Google Patents
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- JP2013534140A5 JP2013534140A5 JP2013523311A JP2013523311A JP2013534140A5 JP 2013534140 A5 JP2013534140 A5 JP 2013534140A5 JP 2013523311 A JP2013523311 A JP 2013523311A JP 2013523311 A JP2013523311 A JP 2013523311A JP 2013534140 A5 JP2013534140 A5 JP 2013534140A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- immortalized
- cell
- reprogramming
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37061510P | 2010-08-04 | 2010-08-04 | |
| US61/370,615 | 2010-08-04 | ||
| US201161441885P | 2011-02-11 | 2011-02-11 | |
| US61/441,885 | 2011-02-11 | ||
| PCT/US2011/046452 WO2012018933A2 (en) | 2010-08-04 | 2011-08-03 | Reprogramming immortalized b cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015248381A Division JP2016039828A (ja) | 2010-08-04 | 2015-12-21 | 不死化b細胞のリプログラミング |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013534140A JP2013534140A (ja) | 2013-09-02 |
| JP2013534140A5 true JP2013534140A5 (cg-RX-API-DMAC7.html) | 2014-08-21 |
| JP5936218B2 JP5936218B2 (ja) | 2016-06-22 |
Family
ID=45560057
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013523311A Active JP5936218B2 (ja) | 2010-08-04 | 2011-08-03 | 不死化b細胞のリプログラミング |
| JP2015248381A Pending JP2016039828A (ja) | 2010-08-04 | 2015-12-21 | 不死化b細胞のリプログラミング |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015248381A Pending JP2016039828A (ja) | 2010-08-04 | 2015-12-21 | 不死化b細胞のリプログラミング |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8765470B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2601289B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5936218B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2806858C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012018933A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2548950T3 (en) | 2009-06-05 | 2017-12-11 | Cellular Dynamics Int Inc | Reprogramming of T cells and hematopoietic cells |
| KR101774206B1 (ko) | 2009-08-07 | 2017-09-04 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
| KR101975688B1 (ko) * | 2010-12-22 | 2019-05-07 | 페이트 세러퓨틱스, 인코포레이티드 | 단세포 분류 및 iPSC의 증강된 재프로그래밍을 위한 세포 배양 플랫폼 |
| CA2841165A1 (en) * | 2011-07-11 | 2013-01-17 | Cellular Dynamics International, Inc. | Methods for cell reprogramming and genome engineering |
| CN102604894B (zh) * | 2012-02-29 | 2014-07-30 | 中国科学院广州生物医药与健康研究院 | 用于制备神经干细胞的培养基及其用途 |
| CA2874259C (en) | 2012-05-23 | 2021-02-09 | Kyoto University | Highly efficient method for establishing induced pluripotent stem cell |
| US10240125B2 (en) | 2013-03-14 | 2019-03-26 | Immusoft Corporation | Methods for in vitro memory B cell differentiation and transduction with VSV-G pseudotyped viral vectors |
| WO2014186766A1 (en) * | 2013-05-17 | 2014-11-20 | The Broad Institute, Inc. | Reprogrammed cells and methods of production and use thereof |
| US10738323B2 (en) | 2013-07-12 | 2020-08-11 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
| KR102670874B1 (ko) | 2014-03-04 | 2024-05-31 | 페이트 세러퓨틱스, 인코포레이티드 | 개선된 재프로그래밍 방법 및 세포 배양 플랫폼 |
| CN105154386B (zh) * | 2014-05-30 | 2018-04-24 | 中国人民解放军第二军医大学东方肝胆外科医院 | 人肝细胞长期维持和增殖传代培养的专用培养基和培养方法 |
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| JP2019507609A (ja) * | 2016-03-02 | 2019-03-22 | フリークエンシー セラピューティクス インコーポレイテッド | WNTおよびTGF−β阻害を用いる、前庭幹細胞の制御された増殖/内耳有毛細胞の発生のための方法 |
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| US10213511B2 (en) | 2016-03-02 | 2019-02-26 | Frequency Therapeutics, Inc. | Thermoreversible compositions for administration of therapeutic agents |
| US11185555B2 (en) | 2016-04-11 | 2021-11-30 | Noah James Harrison | Method to kill pathogenic microbes in a patient |
| KR101957370B1 (ko) * | 2016-06-15 | 2019-03-13 | 한국생명공학연구원 | 자살유전자를 포함한 에피솜 벡터 및 이를 이용한 리프로그래밍 방법 |
| US10221395B2 (en) | 2016-06-16 | 2019-03-05 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| US11572545B2 (en) | 2016-06-16 | 2023-02-07 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| CN108148808B (zh) * | 2016-12-05 | 2020-12-11 | 同济大学 | 有助于诱导生成神经前体细胞的诱导培养基 |
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| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| US20200147146A1 (en) * | 2017-05-02 | 2020-05-14 | Koji Tanabe | Pharmaceutical composition and cosmetic composition |
| WO2018232079A1 (en) | 2017-06-14 | 2018-12-20 | Daley George Q | Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells by episomal plasmid gene transfer |
| US12247226B2 (en) * | 2017-10-11 | 2025-03-11 | Fate Therapeutics, Inc. | Cellular reprogramming using temporal and transient plasmid vector expression system |
| WO2019106163A1 (en) * | 2017-12-01 | 2019-06-06 | Cellectis | Reprogramming of genetically engineered primary immune cells |
| JP7473209B2 (ja) * | 2018-01-29 | 2024-04-23 | 中国科学院動物研究所 | 細胞誘導の方法 |
| US11162071B2 (en) | 2018-08-17 | 2021-11-02 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by upregulating JAG-1 |
| US11617745B2 (en) | 2018-08-17 | 2023-04-04 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by downregulating FOXO |
| CA3115892A1 (en) * | 2018-10-12 | 2020-04-16 | Reneuron Limited | Induced pluripotent cell comprising a controllable transgene for conditional immortalisation |
| GB2617512B (en) * | 2019-04-05 | 2023-12-27 | Earli Inc | Improved methods and compositions for synthetic biomarkers |
| KR20220130158A (ko) | 2020-01-23 | 2022-09-26 | 더 칠드런스 메디칼 센터 코포레이션 | 인간 만능 줄기 세포로부터의 무-간질 t 세포 분화 |
| BR112022018092A2 (pt) | 2020-03-11 | 2022-11-22 | Bit Bio Ltd | Método de gerar células hepáticas |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| EP4255922A1 (en) | 2020-12-03 | 2023-10-11 | Century Therapeutics, Inc. | Genetically engineered cells and uses thereof |
| WO2022216524A1 (en) | 2021-04-07 | 2022-10-13 | Century Therapeutics, Inc. | Combined artificial cell death/reporter system polypeptide for chimeric antigen receptor cell and uses thereof |
| IL307358A (en) | 2021-04-07 | 2023-11-01 | Century Therapeutics Inc | Compositions and methods for generating gamma-delta t cells from induced pluripotent stem cells |
| AU2022253891A1 (en) | 2021-04-07 | 2023-08-24 | Century Therapeutics, Inc. | Gene transfer vectors and methods of engineering cells |
| AU2022255166A1 (en) | 2021-04-07 | 2023-09-28 | Century Therapeutics, Inc. | Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells |
| KR20240100375A (ko) * | 2021-10-20 | 2024-07-01 | 엑시르, 인코포레이티드 | 전-임상 평가를 위한 비-인간 영장류의 개별화된 게놈 어셈블리 및 유도 만능 줄기 세포 라인을 사용하기 위한 조성물 및 방법 |
| US20250064934A1 (en) | 2021-12-29 | 2025-02-27 | Century Therapeutics, Inc. | Genetically engineered cells having anti-cd19 / anti-cd22 chimeric antigen receptors, and uses thereof |
| EP4519319A1 (en) | 2022-05-04 | 2025-03-12 | Century Therapeutics, Inc. | Cells engineered with an hla-e and hla-g transgene |
| CA3257424A1 (en) | 2022-06-08 | 2023-12-14 | Century Therapeutics, Inc. | Genetically modified cells expressing variants of CD16 and NKG2D and their uses |
| WO2023240212A2 (en) | 2022-06-08 | 2023-12-14 | Century Therapeutics, Inc. | Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof |
| CA3257650A1 (en) | 2022-06-08 | 2023-12-14 | Century Therapeutics, Inc. | Immunoeffector cells derived from genetically modified, multipotential stem cells with membrane IL-12 and their uses |
| WO2024102838A1 (en) | 2022-11-09 | 2024-05-16 | Century Therapeutics, Inc. | Engineered interleukin-7 receptors and uses thereof |
| EP4615876A2 (en) | 2022-11-10 | 2025-09-17 | Century Therapeutics, Inc. | Genetically engineered cells having anti-nectin4 chimeric antigen receptors, and uses thereof |
| WO2025101938A2 (en) | 2023-11-10 | 2025-05-15 | Century Therapeutics, Inc. | Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof |
| WO2025106626A1 (en) | 2023-11-15 | 2025-05-22 | Century Therapeutics, Inc. | Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof |
| WO2025207795A1 (en) | 2024-03-26 | 2025-10-02 | Juno Therapeutics, Inc. | Genetically engineered cells having anti-cd33 / anti-cd123 chimeric antigen receptors, and uses thereof |
| WO2025207798A1 (en) | 2024-03-26 | 2025-10-02 | Century Therapeutics, Inc. | Genetically engineered cells having anti-cd123 chimeric antigen receptors, and uses thereof |
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| DK2548950T3 (en) * | 2009-06-05 | 2017-12-11 | Cellular Dynamics Int Inc | Reprogramming of T cells and hematopoietic cells |
| EP4364797A3 (en) | 2009-10-19 | 2024-07-10 | FUJIFILM Cellular Dynamics, Inc. | Cardiomyocyte production |
| JP5898086B2 (ja) | 2009-11-04 | 2016-04-06 | セルラー ダイナミクス インターナショナル, インコーポレイテッド | 化学物質を用いるエピソームリプログラミング |
| CN102597524B (zh) * | 2009-11-06 | 2015-11-25 | 三菱电机株式会社 | 热泵装置、双级压缩机及热泵装置的运转方法 |
| CA2796251C (en) | 2010-04-13 | 2019-05-14 | Cellular Dynamics International, Inc. | Hepatocyte production by forward programming |
| WO2012021632A2 (en) * | 2010-08-10 | 2012-02-16 | The Johns Hopkins University | Generation and use of pluripotent stem cells |
-
2011
- 2011-08-03 US US13/197,529 patent/US8765470B2/en active Active
- 2011-08-03 JP JP2013523311A patent/JP5936218B2/ja active Active
- 2011-08-03 CA CA2806858A patent/CA2806858C/en active Active
- 2011-08-03 EP EP11815273.5A patent/EP2601289B1/en active Active
- 2011-08-03 WO PCT/US2011/046452 patent/WO2012018933A2/en not_active Ceased
-
2014
- 2014-05-21 US US14/284,283 patent/US20140349397A1/en not_active Abandoned
-
2015
- 2015-12-21 JP JP2015248381A patent/JP2016039828A/ja active Pending
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