JP2013530202A5 - - Google Patents

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Publication number
JP2013530202A5
JP2013530202A5 JP2013517372A JP2013517372A JP2013530202A5 JP 2013530202 A5 JP2013530202 A5 JP 2013530202A5 JP 2013517372 A JP2013517372 A JP 2013517372A JP 2013517372 A JP2013517372 A JP 2013517372A JP 2013530202 A5 JP2013530202 A5 JP 2013530202A5
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JP
Japan
Prior art keywords
formula
compound
hal
mixtures
salt
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JP2013517372A
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English (en)
Japanese (ja)
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JP6014589B2 (ja
JP2013530202A (ja
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Priority claimed from PCT/EP2011/061372 external-priority patent/WO2012004287A1/en
Publication of JP2013530202A publication Critical patent/JP2013530202A/ja
Publication of JP2013530202A5 publication Critical patent/JP2013530202A5/ja
Application granted granted Critical
Publication of JP6014589B2 publication Critical patent/JP6014589B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013517372A 2010-07-08 2011-07-06 スフィンゴシン１−リン酸（ｓ１ｐ）受容体上のリガンドとしての５−（ビフェニル−４−イル）−３−フェニル−１，２，４−オキサジアゾリル誘導体 Expired - Fee Related JP6014589B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP10168833.1 2010-07-08
EP10168833 2010-07-08
US36274610P 2010-07-09 2010-07-09
US61/362,746 2010-07-09
PCT/EP2011/061372 WO2012004287A1 (en) 2010-07-08 2011-07-06 5-(biphenyl-4-yl)-3-phenyl-1,2,4-oxadiazolyl derivatives as ligands on the sphingosine 1-phosphate (s1p) receptors

Publications (3)

Publication Number Publication Date
JP2013530202A JP2013530202A (ja) 2013-07-25
JP2013530202A5 true JP2013530202A5 (enExample) 2015-11-05
JP6014589B2 JP6014589B2 (ja) 2016-10-25

Family

ID=42341535

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013517372A Expired - Fee Related JP6014589B2 (ja) 2010-07-08 2011-07-06 スフィンゴシン１−リン酸（ｓ１ｐ）受容体上のリガンドとしての５−（ビフェニル−４−イル）−３−フェニル−１，２，４−オキサジアゾリル誘導体

Country Status (15)

Country Link
US (1) US9029405B2 (enExample)
EP (1) EP2590956B1 (enExample)
JP (1) JP6014589B2 (enExample)
KR (1) KR20140003379A (enExample)
CN (1) CN103097365B (enExample)
AR (1) AR082132A1 (enExample)
AU (1) AU2011275854B2 (enExample)
CA (1) CA2804473C (enExample)
EA (1) EA201300092A1 (enExample)
ES (1) ES2586145T3 (enExample)
IL (1) IL224071B (enExample)
MX (1) MX2012015021A (enExample)
SG (1) SG186872A1 (enExample)
TW (1) TW201206429A (enExample)
WO (1) WO2012004287A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102250035A (zh) * 2011-06-10 2011-11-23 北京富卡生物技术有限公司 二芳基取代-1，3，4-噁二唑化合物的合成方法和其药物用途
CN107857760A (zh) * 2017-11-21 2018-03-30 南京天翔医药科技有限公司 鞘氨醇‑1‑磷酸受体调节剂及其应用
TWI891696B (zh) * 2019-12-23 2025-08-01 英商喜翠克斯治療有限公司 新穎之化合物
EP4126827B1 (en) * 2020-03-27 2024-11-20 Receptos LLC Sphingosine 1 phosphate receptor modulators
US20240228448A1 (en) * 2021-03-31 2024-07-11 Washington University Compositions for binding sphingosine-1-phosphate receptor 1 (s1p1), imaging of s1p1, and processes for preparation thereof
WO2022220608A1 (ko) * 2021-04-14 2022-10-20 주식회사 엘지화학 스핑고신-1-인산 수용체 효능제 합성을 위한 중간체의 제조방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0711792B1 (de) 1994-11-05 1999-03-10 BASF Aktiengesellschaft Melaminharze
JP4773972B2 (ja) * 2003-12-17 2011-09-14 メルク・シャープ・エンド・ドーム・コーポレイション Ｓ１Ｐ（Ｅｄｇ）受容体作働薬としての（３，４−ジ置換）プロパンカルボン酸
US20060223866A1 (en) * 2004-08-13 2006-10-05 Praecis Pharmaceuticals, Inc. Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity
JP2008545767A (ja) * 2005-06-08 2008-12-18 ノバルティス アクチエンゲゼルシャフト 多環式オキサジアゾールまたはイソキサゾールおよびｓｉｐ受容体リガンドとしてのそれらの使用
GB0511684D0 (en) * 2005-06-08 2005-07-13 Novartis Ag Organic compounds
TWI404706B (zh) * 2006-01-11 2013-08-11 Actelion Pharmaceuticals Ltd 新穎噻吩衍生物
GB0601744D0 (en) * 2006-01-27 2006-03-08 Novartis Ag Organic compounds
JP2009269819A (ja) * 2006-08-25 2009-11-19 Asahi Kasei Pharma Kk アミン化合物
KR20090057070A (ko) * 2006-09-29 2009-06-03 노파르티스 아게 소염성 및 면역억제성을 갖는 옥사디아졸 유도체
CA2696863C (en) 2007-10-04 2016-10-18 Anna Quattropani Oxadiazole derivatives
TW201000099A (en) * 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof
EP2241558A1 (en) 2009-04-03 2010-10-20 Merck Serono SA Oxadiazole derivatives

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