JP2013526850A5 - - Google Patents
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- Publication number
- JP2013526850A5 JP2013526850A5 JP2013503215A JP2013503215A JP2013526850A5 JP 2013526850 A5 JP2013526850 A5 JP 2013526850A5 JP 2013503215 A JP2013503215 A JP 2013503215A JP 2013503215 A JP2013503215 A JP 2013503215A JP 2013526850 A5 JP2013526850 A5 JP 2013526850A5
- Authority
- JP
- Japan
- Prior art keywords
- carrier
- gene
- bacteriophage
- component
- protein complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 30
- 108090000623 proteins and genes Proteins 0.000 claims 15
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 241001515965 unidentified phage Species 0.000 claims 7
- 238000004806 packaging method and process Methods 0.000 claims 6
- 239000012634 fragment Substances 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 230000035772 mutation Effects 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- 210000000234 capsid Anatomy 0.000 claims 3
- 108091006112 ATPases Proteins 0.000 claims 2
- 102000057290 Adenosine Triphosphatases Human genes 0.000 claims 2
- 108020004705 Codon Proteins 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 230000002163 immunogen Effects 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 101000870242 Bacillus phage Nf Tail knob protein gp9 Proteins 0.000 claims 1
- 101710104895 DNA replication protein 17 Proteins 0.000 claims 1
- 101710152616 Probable major capsid protein gp17 Proteins 0.000 claims 1
- 102100030350 Prolactin-inducible protein Human genes 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 238000000151 deposition Methods 0.000 claims 1
- 101150035627 hoc gene Proteins 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000000816 peptidomimetic Substances 0.000 claims 1
- 101150044104 soc gene Proteins 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32233410P | 2010-04-09 | 2010-04-09 | |
| US61/322,334 | 2010-04-09 | ||
| US13/082,466 US8802418B2 (en) | 2010-04-09 | 2011-04-08 | Protein and nucleic acid delivery vehicles, components and mechanisms thereof |
| PCT/IB2011/051533 WO2011125054A2 (en) | 2010-04-09 | 2011-04-08 | Protein and nucleic acid delivery vehicles, components and mechanisms thereof |
| US13/082,466 | 2011-04-08 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015250577A Division JP6127124B2 (ja) | 2010-04-09 | 2015-12-22 | タンパク質および核酸送達媒体、その成分および機構 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013526850A JP2013526850A (ja) | 2013-06-27 |
| JP2013526850A5 true JP2013526850A5 (https=) | 2014-04-03 |
| JP5863766B2 JP5863766B2 (ja) | 2016-02-17 |
Family
ID=44761088
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013503215A Active JP5863766B2 (ja) | 2010-04-09 | 2011-04-08 | タンパク質および核酸送達媒体、その成分および機構 |
| JP2015250577A Active JP6127124B2 (ja) | 2010-04-09 | 2015-12-22 | タンパク質および核酸送達媒体、その成分および機構 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015250577A Active JP6127124B2 (ja) | 2010-04-09 | 2015-12-22 | タンパク質および核酸送達媒体、その成分および機構 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8802418B2 (https=) |
| EP (2) | EP2703491B1 (https=) |
| JP (2) | JP5863766B2 (https=) |
| CN (2) | CN103725703B (https=) |
| WO (1) | WO2011125054A2 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2560045A1 (en) * | 2003-12-17 | 2005-06-30 | The Catholic University Of America | Methods and compositions comprising bacteriophage nanoparticles |
| US9163262B2 (en) * | 2003-12-17 | 2015-10-20 | The Catholic University Of America | In vitro and in vivo delivery of genes and proteins using the bacteriophage T4 DNA packaging machine |
| US20120214867A1 (en) * | 2011-02-18 | 2012-08-23 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Bacteriophage T4 Nanoparticles for Eukaryotic Delivery |
| US9765122B2 (en) | 2013-01-18 | 2017-09-19 | University Of Washington Through Its Center For Commercialization | Theragnostic particles |
| US9328149B2 (en) | 2013-07-12 | 2016-05-03 | The Catholic University Of America | Mutated and bacteriophage T4 nanoparticle arrayed F1-V immunogens from Yersinia pestis as next generation plague vaccines |
| SG11201600853UA (en) | 2013-08-05 | 2016-03-30 | Twist Bioscience Corp | De novo synthesized gene libraries |
| WO2016115522A2 (en) * | 2015-01-16 | 2016-07-21 | University Of Kentucky Research Foundation | Lipid bilayer-integrated spp1 connector protein nanopore and spp1 connector protein variants for use as lipid bilayer-integrated nanopore |
| US10669304B2 (en) | 2015-02-04 | 2020-06-02 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| EP3350314A4 (en) | 2015-09-18 | 2019-02-06 | Twist Bioscience Corporation | OLIGONUCLEIC ACID VARIANT LIBRARIES VARIANT AND SYNTHESIS THEREOF |
| KR102794025B1 (ko) | 2015-09-22 | 2025-04-09 | 트위스트 바이오사이언스 코포레이션 | 핵산 합성을 위한 가요성 기판 |
| US20180112234A9 (en) | 2016-03-14 | 2018-04-26 | Intellia Therapeutics, Inc. | Methods and compositions for gene editing |
| WO2017165859A1 (en) * | 2016-03-24 | 2017-09-28 | Research Institute At Nationwide Children's Hospital | Modified viral capsid proteins |
| US10417457B2 (en) | 2016-09-21 | 2019-09-17 | Twist Bioscience Corporation | Nucleic acid based data storage |
| EP4556433A3 (en) | 2017-02-22 | 2025-08-06 | Twist Bioscience Corporation | Nucleic acid based data storage |
| CN106939355A (zh) * | 2017-03-01 | 2017-07-11 | 苏州系统医学研究所 | 一种流感病毒弱毒活疫苗毒株的筛选和鉴定方法 |
| CN108949701A (zh) * | 2017-05-26 | 2018-12-07 | 中国科学院深圳先进技术研究院 | 一种猴类脑区的病毒注射方法及应用 |
| CA3065946A1 (en) | 2017-06-05 | 2018-12-13 | Research Institute At Nationwide Children's Hospital | Enhanced modified viral capsid proteins |
| CN111565834B (zh) | 2017-10-20 | 2022-08-26 | 特韦斯特生物科学公司 | 用于多核苷酸合成的加热的纳米孔 |
| CA3100739A1 (en) | 2018-05-18 | 2019-11-21 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
| AU2019293286A1 (en) | 2018-06-28 | 2021-01-07 | Crispr Therapeutics Ag | Compositions and methods for genomic editing by insertion of donor polynucleotides |
| WO2020139871A1 (en) | 2018-12-26 | 2020-07-02 | Twist Bioscience Corporation | Highly accurate de novo polynucleotide synthesis |
| JP2022522668A (ja) | 2019-02-26 | 2022-04-20 | ツイスト バイオサイエンス コーポレーション | 抗体を最適化するための変異体核酸ライブラリ |
| CN113766930B (zh) | 2019-02-26 | 2025-07-22 | 特韦斯特生物科学公司 | Glp1受体的变异核酸文库 |
| US20210047649A1 (en) | 2019-05-08 | 2021-02-18 | Vertex Pharmaceuticals Incorporated | Crispr/cas all-in-two vector systems for treatment of dmd |
| EP3983542A2 (en) | 2019-06-17 | 2022-04-20 | CRISPR Therapeutics AG | Methods and compositions for improved homology directed repair |
| US11155835B2 (en) * | 2019-08-19 | 2021-10-26 | The Catholic University Of America | Prokaryotic-eukaryotic hybrid viral vector for delivery of large cargos of genes and proteins into human cells |
| EP4034566A4 (en) | 2019-09-23 | 2024-01-24 | Twist Bioscience Corporation | VARIANT NUCLEIC ACID BANKS FOR CRTH2 |
| JP2022548783A (ja) | 2019-09-23 | 2022-11-21 | ツイスト バイオサイエンス コーポレーション | 単一ドメイン抗体のバリアント核酸ライブラリー |
| WO2021140615A1 (ja) * | 2020-01-09 | 2021-07-15 | 哲朗 近藤 | 新規組換えバクテリオファージ |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5736388A (en) | 1994-12-30 | 1998-04-07 | Chada; Sunil | Bacteriophage-mediated gene transfer systems capable of transfecting eukaryotic cells |
| CA2560045A1 (en) * | 2003-12-17 | 2005-06-30 | The Catholic University Of America | Methods and compositions comprising bacteriophage nanoparticles |
| CA2585267A1 (en) * | 2004-10-29 | 2007-02-08 | University Of Rochester | Modified bacteriophage vectors and uses thereof |
| MX2009009213A (es) | 2007-03-01 | 2010-03-15 | Univ America Catholic | Bacteriofago t4 unido a un substrato. |
| US9217145B2 (en) * | 2007-05-15 | 2015-12-22 | Wisconsin Alumni Research Foundation | T7 phage peptide display system and uses thereof |
| JP2010529862A (ja) * | 2007-06-16 | 2010-09-02 | スカラブ ゲノミクス， エルエルシー | 核酸パッケージングシステム |
-
2011
- 2011-04-08 EP EP13194914.1A patent/EP2703491B1/en active Active
- 2011-04-08 US US13/082,466 patent/US8802418B2/en active Active
- 2011-04-08 CN CN201410005350.7A patent/CN103725703B/zh active Active
- 2011-04-08 EP EP11765160.4A patent/EP2542681B1/en active Active
- 2011-04-08 JP JP2013503215A patent/JP5863766B2/ja active Active
- 2011-04-08 CN CN201180030396.9A patent/CN103003431B/zh active Active
- 2011-04-08 WO PCT/IB2011/051533 patent/WO2011125054A2/en not_active Ceased
-
2013
- 2013-03-12 US US13/796,263 patent/US9365867B2/en active Active
-
2014
- 2014-07-02 US US14/322,097 patent/US9523101B2/en active Active
-
2015
- 2015-12-22 JP JP2015250577A patent/JP6127124B2/ja active Active
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