JP2016528176A5 - - Google Patents
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- Publication number
- JP2016528176A5 JP2016528176A5 JP2016517683A JP2016517683A JP2016528176A5 JP 2016528176 A5 JP2016528176 A5 JP 2016528176A5 JP 2016517683 A JP2016517683 A JP 2016517683A JP 2016517683 A JP2016517683 A JP 2016517683A JP 2016528176 A5 JP2016528176 A5 JP 2016528176A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- nucleic acid
- acid molecule
- hbcag
- copies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004169 proteins and genes Human genes 0.000 claims 25
- 108090000623 proteins and genes Proteins 0.000 claims 25
- 102000039446 nucleic acids Human genes 0.000 claims 10
- 108020004707 nucleic acids Proteins 0.000 claims 10
- 150000007523 nucleic acids Chemical class 0.000 claims 10
- 238000000034 method Methods 0.000 claims 9
- 101710132601 Capsid protein Proteins 0.000 claims 8
- 239000002245 particle Substances 0.000 claims 8
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 5
- 108010003723 Single-Domain Antibodies Proteins 0.000 claims 5
- 241001465754 Metazoa Species 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 239000002671 adjuvant Substances 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 102000006830 Luminescent Proteins Human genes 0.000 claims 1
- 108010047357 Luminescent Proteins Proteins 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 102000034287 fluorescent proteins Human genes 0.000 claims 1
- 108091006047 fluorescent proteins Proteins 0.000 claims 1
- 208000002672 hepatitis B Diseases 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361831707P | 2013-06-06 | 2013-06-06 | |
| US61/831,707 | 2013-06-06 | ||
| PCT/GB2014/051739 WO2014195713A1 (en) | 2013-06-06 | 2014-06-05 | Single domain antibody display |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016528176A JP2016528176A (ja) | 2016-09-15 |
| JP2016528176A5 true JP2016528176A5 (https=) | 2017-07-13 |
Family
ID=51022893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016517683A Pending JP2016528176A (ja) | 2013-06-06 | 2014-06-05 | シングルドメイン抗体ディスプレイ |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20160122420A1 (https=) |
| EP (1) | EP3004173B1 (https=) |
| JP (1) | JP2016528176A (https=) |
| CN (1) | CN105431457A (https=) |
| CA (1) | CA2914555A1 (https=) |
| WO (1) | WO2014195713A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201402890D0 (en) | 2014-02-18 | 2014-04-02 | Iqur Ltd | Vaccines based on hepatitis B Core antigens |
| GB201421692D0 (en) * | 2014-12-05 | 2015-01-21 | Iquar Ltd | Vaccines based on hepatitis B core antigens |
| US10544210B2 (en) * | 2015-02-03 | 2020-01-28 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Anti-Rho GTPase conformational single domain antibodies and uses thereof |
| US11078240B2 (en) | 2016-11-11 | 2021-08-03 | Fraunhofer Usa Inc. | Covalently fused viral coat proteins for the display of target molecules |
| CN113138276B (zh) * | 2020-01-19 | 2022-09-16 | 厦门万泰凯瑞生物技术有限公司 | 用于检测HBcAg的方法及抗体 |
| WO2021168575A1 (en) * | 2020-02-27 | 2021-09-02 | Quadrumix Biotechnology Inc. | Polypeptides directed against viral infection and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2489769A1 (en) | 1989-03-21 | 1990-10-04 | Philip L. Felgner | Expression of exogenous polynucleotide sequences in a vertebrate |
| US5279833A (en) | 1990-04-04 | 1994-01-18 | Yale University | Liposomal transfection of nucleic acids into animal cells |
| US5283185A (en) | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
| CA2131620A1 (en) | 1992-03-20 | 1993-09-30 | Louis C. Smith | A dna transporter system and method of use |
| WO1993019768A1 (en) | 1992-04-03 | 1993-10-14 | The Regents Of The University Of California | Self-assembling polynucleotide delivery system |
| US5651981A (en) | 1994-03-29 | 1997-07-29 | Northwestern University | Cationic phospholipids for transfection |
| US5527928A (en) | 1994-09-30 | 1996-06-18 | Nantz; Michael H. | Cationic transport reagents |
| DE60122300T2 (de) * | 2000-04-07 | 2007-08-30 | The University Of Leeds | Hepatitis b kernprotein fusionsproteine |
| JP4791730B2 (ja) | 2002-09-27 | 2011-10-12 | パウダージェクト リサーチ リミテッド | 核酸コーティング粒子 |
| US20120015899A1 (en) * | 2008-10-25 | 2012-01-19 | Plant Bioscience, Limited | Modified plant virus particles and uses therefor |
| GB0918679D0 (en) * | 2009-10-23 | 2009-12-09 | Iqur Ltd | Influenza vaccine |
| US20130017210A1 (en) * | 2010-03-17 | 2013-01-17 | Stc.Unm | Display of antibody fragments on virus-like particles of rna bacteriophages |
-
2014
- 2014-06-05 EP EP14733677.0A patent/EP3004173B1/en not_active Not-in-force
- 2014-06-05 WO PCT/GB2014/051739 patent/WO2014195713A1/en not_active Ceased
- 2014-06-05 JP JP2016517683A patent/JP2016528176A/ja active Pending
- 2014-06-05 CA CA2914555A patent/CA2914555A1/en not_active Abandoned
- 2014-06-05 US US14/896,343 patent/US20160122420A1/en not_active Abandoned
- 2014-06-05 CN CN201480041470.0A patent/CN105431457A/zh active Pending
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