JP2013522367A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013522367A5 JP2013522367A5 JP2013501396A JP2013501396A JP2013522367A5 JP 2013522367 A5 JP2013522367 A5 JP 2013522367A5 JP 2013501396 A JP2013501396 A JP 2013501396A JP 2013501396 A JP2013501396 A JP 2013501396A JP 2013522367 A5 JP2013522367 A5 JP 2013522367A5
- Authority
- JP
- Japan
- Prior art keywords
- cem
- diffraction pattern
- powder diffraction
- ray powder
- peaks
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31606310P | 2010-03-22 | 2010-03-22 | |
| US61/316,063 | 2010-03-22 | ||
| PCT/US2011/029424 WO2011119604A1 (en) | 2010-03-22 | 2011-03-22 | Crystalline forms of a macrolide, and uses therefor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014231987A Division JP6121387B2 (ja) | 2010-03-22 | 2014-11-14 | マクロライドの結晶形、およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013522367A JP2013522367A (ja) | 2013-06-13 |
| JP2013522367A5 true JP2013522367A5 (enExample) | 2014-05-15 |
| JP5711352B2 JP5711352B2 (ja) | 2015-04-30 |
Family
ID=44673574
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013501396A Active JP5711352B2 (ja) | 2010-03-22 | 2011-03-22 | マクロライドの結晶形、およびその使用 |
| JP2014231987A Active JP6121387B2 (ja) | 2010-03-22 | 2014-11-14 | マクロライドの結晶形、およびその使用 |
| JP2016244733A Pending JP2017081953A (ja) | 2010-03-22 | 2016-12-16 | マクロライドの結晶形、およびその使用 |
| JP2019163614A Pending JP2020002168A (ja) | 2010-03-22 | 2019-09-09 | マクロライドの結晶形、およびその使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014231987A Active JP6121387B2 (ja) | 2010-03-22 | 2014-11-14 | マクロライドの結晶形、およびその使用 |
| JP2016244733A Pending JP2017081953A (ja) | 2010-03-22 | 2016-12-16 | マクロライドの結晶形、およびその使用 |
| JP2019163614A Pending JP2020002168A (ja) | 2010-03-22 | 2019-09-09 | マクロライドの結晶形、およびその使用 |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US8975386B2 (enExample) |
| EP (2) | EP2550286B1 (enExample) |
| JP (4) | JP5711352B2 (enExample) |
| KR (2) | KR20180101643A (enExample) |
| CN (2) | CN103080122A (enExample) |
| AU (2) | AU2011232627B2 (enExample) |
| BR (1) | BR112012023950A2 (enExample) |
| CA (1) | CA2793884C (enExample) |
| DK (1) | DK2550286T3 (enExample) |
| ES (1) | ES2564097T3 (enExample) |
| HR (1) | HRP20160168T1 (enExample) |
| IL (1) | IL222018B (enExample) |
| MX (1) | MX361413B (enExample) |
| MY (1) | MY162411A (enExample) |
| NZ (1) | NZ602544A (enExample) |
| PL (1) | PL2550286T3 (enExample) |
| RU (1) | RU2650883C2 (enExample) |
| SI (1) | SI2550286T1 (enExample) |
| WO (1) | WO2011119604A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2801100A1 (en) | 2003-03-10 | 2004-09-23 | Optimer Pharmaceuticals, Inc. | Macrolides and processes for their preparation |
| WO2009055557A1 (en) | 2007-10-25 | 2009-04-30 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| EP2365747B1 (en) | 2008-10-24 | 2018-04-11 | Cempra Pharmaceuticals, Inc. | Methods for treating gastrointestinal diseases |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| WO2011032052A1 (en) | 2009-09-10 | 2011-03-17 | Cempra Pharmaceuticals, Inc. | Methods for treating malaria, tuberculosis and mac diseases |
| KR20180101643A (ko) | 2010-03-22 | 2018-09-12 | 셈프라 파마슈티컬스, 인크. | 매크로라이드의 결정 형태들 및 그 용도들 |
| CN105198944B (zh) | 2010-05-20 | 2018-06-01 | 森普拉制药公司 | 制备大环内酯和酮内酯及其中间体的方法 |
| US9815863B2 (en) | 2010-09-10 | 2017-11-14 | Cempra Pharmaceuticals, Inc. | Hydrogen bond forming fluoro ketolides for treating diseases |
| JP6208742B2 (ja) | 2012-03-27 | 2017-10-04 | センプラ ファーマシューティカルズ，インコーポレイテッド | マクロライド抗生物質を投与するための非経口製剤 |
| AU2014239959A1 (en) | 2013-03-14 | 2015-10-01 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| KR20160020403A (ko) | 2013-03-15 | 2016-02-23 | 셈프라 파마슈티컬스, 인크. | 매크로라이드 항세균제들을 제조하기 위한 수렴 프로세스들 |
| KR102528984B1 (ko) | 2013-04-04 | 2023-05-08 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 매크롤라이드 그리고 그의 제조방법 및 용도 |
| SG11201700827RA (en) * | 2014-08-05 | 2017-03-30 | Cempra Pharmaceuticals Inc | Powder oral suspension formulations of antibacterial agents |
| CN104151382B (zh) * | 2014-08-08 | 2016-09-14 | 广东东阳光药业有限公司 | 一种固态大环内酯的晶型 |
| CN104311611B (zh) * | 2014-08-13 | 2017-01-18 | 广东东阳光药业有限公司 | 一种制备固态大环内酯的方法 |
| JP2017531663A (ja) | 2014-10-08 | 2017-10-26 | プレジデント アンド フェローズ オブ ハーバード カレッジ | １４員ケトライドならびにそれらの調製および使用の方法 |
| HK1250371A1 (zh) | 2015-03-25 | 2018-12-14 | President And Fellows Of Harvard College | 具有修饰的脱氧糖胺糖的大环内酯及其用途 |
| JP6112696B1 (ja) * | 2015-10-05 | 2017-04-12 | 富山化学工業株式会社 | ソリスロマイシンを含む錠剤 |
| EP3190122A1 (en) * | 2016-01-08 | 2017-07-12 | LEK Pharmaceuticals d.d. | A novel synthetic pathway towards solithromycin and purification thereof |
| TW201811811A (zh) * | 2016-09-02 | 2018-04-01 | 森普拉製藥公司 | 製備氟酮內酯之方法 |
| CN115003309B (zh) * | 2019-12-02 | 2024-05-24 | 阿里量子解决方法公司 | 一种具有结构式i的化合物的晶型 |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4331803A (en) | 1980-06-04 | 1982-05-25 | Taisho Pharmaceutical Co., Ltd. | Novel erythromycin compounds |
| US4474768A (en) | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
| US4742049A (en) | 1986-06-04 | 1988-05-03 | Abbott Laboratories | Semisynthetic erythromycin antibiotics |
| IL99995A (en) | 1990-11-21 | 1997-11-20 | Roussel Uclaf | Erythromycin derivatives, their preparation and pharmaceutical compositions containing them |
| US5985844A (en) | 1992-03-26 | 1999-11-16 | Merck & Co., Inc. | Homoerythromycin A derivatives modified at the 4"-and 8A-positions |
| US5527780A (en) | 1992-11-05 | 1996-06-18 | Roussel Uclaf | Erythromycin derivatives |
| FR2697524B1 (fr) | 1992-11-05 | 1994-12-23 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| FR2718450B1 (fr) | 1994-04-08 | 1997-01-10 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| FR2719587B1 (fr) | 1994-05-03 | 1996-07-12 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| US5834428A (en) | 1995-04-14 | 1998-11-10 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
| FR2739620B1 (fr) | 1995-10-09 | 1997-12-19 | Roussel Uclaf | Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs |
| US6274715B1 (en) | 1995-11-08 | 2001-08-14 | Abbott Laboratories | Tricyclic erythromycin derivatives |
| FR2742757B1 (fr) | 1995-12-22 | 1998-01-30 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| FR2745290B1 (fr) | 1996-02-28 | 1998-04-03 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| PT1291350E (pt) | 1996-09-04 | 2005-09-30 | Abbott Lab | Cetolidos 6-o-substituidos que possuem actividade antibacteriana |
| HN1998000086A (es) | 1997-06-11 | 1999-03-08 | Pfizer Prod Inc | Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos. |
| JP2000513026A (ja) | 1997-06-11 | 2000-10-03 | ファイザー・プロダクツ・インク | ９−オキシム エリスロマイシン誘導体 |
| US6407074B1 (en) | 1997-06-11 | 2002-06-18 | Pfizer Inc | C-4″-substituted macrolide derivatives |
| HN1998000159A (es) | 1997-10-29 | 1999-02-09 | Monsanto Co | Derivados de 9- amino - 3 ceto eritromicina |
| IL135792A0 (en) | 1997-12-01 | 2001-05-20 | Abbott Lab | 6-o-alkyl derivatives of erythronolide b |
| FR2777282B1 (fr) | 1998-04-08 | 2001-04-20 | Hoechst Marion Roussel Inc | Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments |
| US6020521A (en) | 1998-08-26 | 2000-02-01 | Abbott Laboratories | Macrolide LHRH antagonists |
| US6387885B1 (en) | 1998-08-26 | 2002-05-14 | Abbott Laboratories | 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists |
| FR2785612A1 (fr) | 1998-11-10 | 2000-05-12 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| KR100317907B1 (ko) * | 1998-11-24 | 2001-12-24 | 김 완 주 | 신규한 중간체, 이를 이용한 마크로라이드계 항생제의제조방법 |
| FR2786188B1 (fr) | 1998-11-24 | 2002-10-31 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments |
| EP1137654A1 (en) | 1998-12-10 | 2001-10-04 | Pfizer Products Inc. | Carbamate and carbazate ketolide antibiotics |
| EE200100394A (et) | 1999-01-27 | 2002-10-15 | Pfizer Products Inc. | Ketoliidsed antibiootikumid |
| CA2292359C (en) | 1999-01-28 | 2004-09-28 | Pfizer Products Inc. | Novel azalides and methods of making same |
| AU773678B2 (en) | 1999-04-16 | 2004-06-03 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| EP1171447A2 (en) | 1999-04-16 | 2002-01-16 | Ortho-McNeil Pharmaceutical, Inc. | Ketolide antibacterials |
| US6420535B1 (en) | 1999-06-07 | 2002-07-16 | Abbott Laboratories | 6-O-carbamate ketolide derivatives |
| US6437106B1 (en) | 1999-06-24 | 2002-08-20 | Abbott Laboratories | Process for preparing 6-o-substituted erythromycin derivatives |
| AU6183700A (en) | 1999-08-06 | 2001-03-05 | Taisho Pharmaceutical Co., Ltd. | Erythromycin a derivatives |
| KR100336447B1 (ko) | 1999-11-24 | 2002-05-15 | 민경윤 | 클라리스로마이신의 개선된 제조방법 |
| JP2001261694A (ja) | 2000-03-06 | 2001-09-26 | Pfizer Prod Inc | ケトライド抗生物質 |
| MXPA02008861A (es) * | 2000-03-15 | 2003-02-10 | Hanmi Pharm Ind Co Ltd | Metodo para preparar claritromicina de cristales de forma ii. |
| US20020115621A1 (en) | 2000-08-07 | 2002-08-22 | Wei-Gu Su | Macrolide antibiotics |
| GB0031312D0 (en) | 2000-12-21 | 2001-02-07 | Glaxo Group Ltd | Macrolides |
| DE60210402T2 (de) | 2001-05-18 | 2006-12-07 | Chiron Corp., Emeryville | System zur Abgabe einer Tobramycin-Formulierung |
| US6756359B2 (en) | 2001-07-03 | 2004-06-29 | Chiron Corporation | C12 modified erythromycin macrolides and ketolides having antibacterial activity |
| US20030176327A1 (en) | 2001-10-25 | 2003-09-18 | Cassell Gail Houston | Antibiotics for treating biohazardous bacterial agents |
| AR038576A1 (es) | 2002-02-22 | 2005-01-19 | Pharmacia Corp | Formulaciones de drogas antibioticas oftalmicas que contienen un compuesto de ciclodextrina y cloruro de cetil piridinio |
| JP4638225B2 (ja) | 2002-05-30 | 2011-02-23 | ザ スクリプス リサーチ インスティテュート | 銅を触媒とするアジドとアセチレンのライゲーション |
| US7091196B2 (en) | 2002-09-26 | 2006-08-15 | Rib-X Pharmaceuticals, Inc. | Bifunctional heterocyclic compounds and methods of making and using same |
| ITMI20022292A1 (it) | 2002-10-29 | 2004-04-30 | Zambon Spa | 9a-azalidi ad attivita' antiinfiammatoria. |
| CA2801100A1 (en) * | 2003-03-10 | 2004-09-23 | Optimer Pharmaceuticals, Inc. | Macrolides and processes for their preparation |
| WO2004096823A2 (en) | 2003-04-25 | 2004-11-11 | Chiron Corporation | Novel ketolide derivatives |
| US20050014706A1 (en) | 2003-07-14 | 2005-01-20 | Kanakeshwari Falzari | Method of treating tuberculosis |
| US7457520B2 (en) | 2003-07-24 | 2008-11-25 | Time Warner Cable, Inc. | Technique for providing a virtual digital video recorder service through a communications network |
| US20060116336A1 (en) | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
| EP1742957B1 (en) | 2004-04-28 | 2007-09-12 | Alembic Limited | Process for the preparation of telithromycin |
| US20080287376A1 (en) | 2004-07-28 | 2008-11-20 | Mohammad Salman | Ketolide Derivatives as Antibacterial Agents |
| EA011281B1 (ru) * | 2004-12-21 | 2009-02-27 | Пфайзер Продактс Инк. | Макролиды |
| WO2006075256A2 (en) | 2005-01-14 | 2006-07-20 | Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. | 9a-carbamoyl-ϝ-aminopropyl- and 9a-thiocarbamoyl-ϝ-aminopropyl-azalides with antimalarial activity |
| WO2007039914A2 (en) | 2005-10-06 | 2007-04-12 | Alembic Limited | Novel polymorphs of telithromycin |
| WO2007059307A2 (en) * | 2005-11-15 | 2007-05-24 | Teva Pharmaceutical Industries Ltd. | Crystalline and amorphous forms of telithromycin |
| EP1954294A2 (en) | 2005-11-23 | 2008-08-13 | Ranbaxy Laboratories Limited | Use of macrolide derivatives for treating acne |
| DOP2006000268A (es) | 2005-12-22 | 2007-07-31 | Pfizer Prod Inc | Agentes antibacterianos |
| CN101129383B (zh) | 2006-08-25 | 2014-04-02 | 天津和美生物技术有限公司 | 含氨基糖苷类抗生素的抗生素复方 |
| US7742562B2 (en) * | 2007-06-27 | 2010-06-22 | Accuray Incorporated | Lower-torso assembly of a treatment couch useable in an X-ray environment |
| EP2220104A1 (en) | 2007-10-25 | 2010-08-25 | Sandoz AG | Process for the production of telithromycin |
| WO2009055557A1 (en) * | 2007-10-25 | 2009-04-30 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| EP2365747B1 (en) * | 2008-10-24 | 2018-04-11 | Cempra Pharmaceuticals, Inc. | Methods for treating gastrointestinal diseases |
| JP5890785B2 (ja) | 2010-03-10 | 2016-03-22 | センプラ ファーマシューティカルズ，インコーポレイテッド | マクロライド抗生物質の非経口製剤 |
| KR20180101643A (ko) | 2010-03-22 | 2018-09-12 | 셈프라 파마슈티컬스, 인크. | 매크로라이드의 결정 형태들 및 그 용도들 |
-
2011
- 2011-03-22 KR KR1020187025895A patent/KR20180101643A/ko not_active Ceased
- 2011-03-22 BR BR112012023950A patent/BR112012023950A2/pt not_active Application Discontinuation
- 2011-03-22 CN CN2011800174629A patent/CN103080122A/zh active Pending
- 2011-03-22 EP EP11760068.4A patent/EP2550286B1/en not_active Revoked
- 2011-03-22 PL PL11760068T patent/PL2550286T3/pl unknown
- 2011-03-22 US US13/636,510 patent/US8975386B2/en not_active Expired - Fee Related
- 2011-03-22 NZ NZ602544A patent/NZ602544A/en not_active IP Right Cessation
- 2011-03-22 EP EP15194057.4A patent/EP3009442B1/en active Active
- 2011-03-22 AU AU2011232627A patent/AU2011232627B2/en not_active Ceased
- 2011-03-22 MX MX2012010895A patent/MX361413B/es active IP Right Grant
- 2011-03-22 CA CA2793884A patent/CA2793884C/en not_active Expired - Fee Related
- 2011-03-22 DK DK11760068.4T patent/DK2550286T3/en active
- 2011-03-22 JP JP2013501396A patent/JP5711352B2/ja active Active
- 2011-03-22 RU RU2012144614A patent/RU2650883C2/ru not_active IP Right Cessation
- 2011-03-22 WO PCT/US2011/029424 patent/WO2011119604A1/en not_active Ceased
- 2011-03-22 KR KR1020127027222A patent/KR102006200B1/ko not_active Expired - Fee Related
- 2011-03-22 ES ES11760068.4T patent/ES2564097T3/es active Active
- 2011-03-22 MY MYPI2012004183A patent/MY162411A/en unknown
- 2011-03-22 SI SI201130745T patent/SI2550286T1/sl unknown
- 2011-03-22 CN CN201810569806.0A patent/CN108570083A/zh active Pending
- 2011-03-22 HR HRP20160168T patent/HRP20160168T1/hr unknown
-
2012
- 2012-09-20 IL IL222018A patent/IL222018B/en not_active IP Right Cessation
-
2013
- 2013-05-22 US US13/900,147 patent/US8759500B2/en not_active Expired - Fee Related
-
2014
- 2014-11-14 JP JP2014231987A patent/JP6121387B2/ja active Active
-
2015
- 2015-09-21 US US14/859,736 patent/US20160244472A1/en not_active Abandoned
-
2016
- 2016-06-15 AU AU2016203986A patent/AU2016203986B2/en not_active Ceased
- 2016-12-16 JP JP2016244733A patent/JP2017081953A/ja active Pending
-
2018
- 2018-02-26 US US15/904,826 patent/US20190040096A1/en not_active Abandoned
-
2019
- 2019-09-09 JP JP2019163614A patent/JP2020002168A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013522367A5 (enExample) | ||
| JP2012144574A5 (enExample) | ||
| PH12014500164A1 (en) | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease | |
| JP2013525444A5 (enExample) | ||
| WO2013040286A3 (en) | Pharmaceutical compositions | |
| WO2012021796A3 (en) | Novel cyclosporin derivatives for the treatment and prevention of a viral infection | |
| WO2012018534A3 (en) | Substituted biphenylene compounds and methods of use thereof for the treatment of viral diseases | |
| EA201490228A1 (ru) | Новые производные трифторметилоксадиазола и их применение для лечения заболевания | |
| WO2012142093A3 (en) | 2'-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases | |
| WO2012009715A3 (en) | Novel cyclosporin derivatives for the treatment and prevention of a viral infection | |
| BR112013030045A2 (pt) | composto da fórmula d-m-d ou um sal farmacêuticamente aceitável do mesmo; composto ou sal; composição farmacêutica; e método de tratamento de infecção por hepatite c em um paciente | |
| WO2013066835A3 (en) | Compounds and methods | |
| EA201491060A1 (ru) | Новые производные трифторметилоксадиазола и их применение для лечения заболевания | |
| WO2011127333A3 (en) | Compounds for treating disease, for administering, and for pharmaceutical compositions | |
| JP2011037901A5 (enExample) | ||
| MX2013011589A (es) | Metodos y composiciones para tratar enfermedad de parkinson. | |
| EA201390917A1 (ru) | Дигетероарильные соединения в качестве ингибиторов vps34 | |
| PE20120989A1 (es) | Sales de disacarina, acido difumarico, acido d-1-hidroxi-2-naftoico y monobenzoico del 2-(4-((2-amino-4-metil-6-(pentilamino) pirimidin-5-il) metil) fenil) acetato de 4-(dimetilamino) butilo | |
| HK1215579A1 (zh) | 被取代的2，3-二氫苯並呋喃基化合物和其用途 | |
| UA110983C2 (uk) | Похідна 1,2,3,4-тетрагідрохіноліну, придатна для лікування діабету | |
| MX350746B (es) | Derivados de ciclosporina novedosos para el tratamiento y la prevención de una infección viral. | |
| EA033054B1 (ru) | Производное глутаримидов, его применение, фармацевтическая композиция на его основе, способ его получения | |
| WO2013028818A8 (en) | Pyrimido- pyridazinone compounds and use thereof | |
| WO2010107807A3 (en) | Compounds for treating inflammation and pain | |
| JP2011088926A5 (enExample) |