ES2564097T3 - Formas cristalinas de un macrólido, y usos de las mismas - Google Patents

Formas cristalinas de un macrólido, y usos de las mismas Download PDF

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Publication number
ES2564097T3
ES2564097T3 ES11760068.4T ES11760068T ES2564097T3 ES 2564097 T3 ES2564097 T3 ES 2564097T3 ES 11760068 T ES11760068 T ES 11760068T ES 2564097 T3 ES2564097 T3 ES 2564097T3
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water
solid
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added
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ES11760068.4T
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English (en)
Spanish (es)
Inventor
David E. Pereira
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Cempra Pharmaceuticals Inc
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Cempra Pharmaceuticals Inc
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Application filed by Cempra Pharmaceuticals Inc filed Critical Cempra Pharmaceuticals Inc
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES11760068.4T 2010-03-22 2011-03-22 Formas cristalinas de un macrólido, y usos de las mismas Active ES2564097T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US316063P 2001-08-30
US31606310P 2010-03-22 2010-03-22
PCT/US2011/029424 WO2011119604A1 (en) 2010-03-22 2011-03-22 Crystalline forms of a macrolide, and uses therefor

Publications (1)

Publication Number Publication Date
ES2564097T3 true ES2564097T3 (es) 2016-03-17

Family

ID=44673574

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11760068.4T Active ES2564097T3 (es) 2010-03-22 2011-03-22 Formas cristalinas de un macrólido, y usos de las mismas

Country Status (19)

Country Link
US (4) US8975386B2 (enExample)
EP (2) EP3009442B1 (enExample)
JP (4) JP5711352B2 (enExample)
KR (2) KR20180101643A (enExample)
CN (2) CN108570083A (enExample)
AU (2) AU2011232627B2 (enExample)
BR (1) BR112012023950A2 (enExample)
CA (1) CA2793884C (enExample)
DK (1) DK2550286T3 (enExample)
ES (1) ES2564097T3 (enExample)
HR (1) HRP20160168T1 (enExample)
IL (1) IL222018B (enExample)
MX (1) MX361413B (enExample)
MY (1) MY162411A (enExample)
NZ (1) NZ602544A (enExample)
PL (1) PL2550286T3 (enExample)
RU (1) RU2650883C2 (enExample)
SI (1) SI2550286T1 (enExample)
WO (1) WO2011119604A1 (enExample)

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US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
CN102245195B (zh) 2008-10-24 2016-01-13 森普拉制药公司 使用含三唑的大环内酯的生物防御
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ，インコーポレイテッド マラリア、結核、及びｍａｃ病の治療方法
EP3009442B1 (en) 2010-03-22 2019-06-19 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
CA2799937A1 (en) 2010-05-20 2011-11-24 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
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JP2017523975A (ja) * 2014-08-05 2017-08-24 センプラ ファーマシューティカルズ，インコーポレイテッド 経口抗菌薬粉末懸濁製剤
CN104151382B (zh) * 2014-08-08 2016-09-14 广东东阳光药业有限公司 一种固态大环内酯的晶型
CN104311611B (zh) * 2014-08-13 2017-01-18 广东东阳光药业有限公司 一种制备固态大环内酯的方法
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TW201811811A (zh) * 2016-09-02 2018-04-01 森普拉製藥公司 製備氟酮內酯之方法
JP7693669B2 (ja) * 2019-12-02 2025-06-17 アリクァンタムアールエクス，インコーポレイテッド 疾患の治療のためのセスロマイシンの塩及び多形体 セスロマイシンの塩及び多形体

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Also Published As

Publication number Publication date
KR102006200B1 (ko) 2019-08-01
CA2793884A1 (en) 2011-09-29
RU2012144614A (ru) 2014-04-27
CN108570083A (zh) 2018-09-25
PL2550286T3 (pl) 2016-07-29
AU2011232627B2 (en) 2016-03-17
BR112012023950A2 (pt) 2016-07-05
JP6121387B2 (ja) 2017-04-26
KR20130056226A (ko) 2013-05-29
JP2017081953A (ja) 2017-05-18
JP5711352B2 (ja) 2015-04-30
US8975386B2 (en) 2015-03-10
US20130252915A1 (en) 2013-09-26
JP2020002168A (ja) 2020-01-09
KR20180101643A (ko) 2018-09-12
MX361413B (es) 2018-12-05
US20190040096A1 (en) 2019-02-07
AU2011232627A1 (en) 2012-10-18
HK1177937A1 (en) 2013-08-30
EP2550286A4 (en) 2013-10-02
SI2550286T1 (sl) 2016-04-29
JP2013522367A (ja) 2013-06-13
EP3009442A1 (en) 2016-04-20
EP2550286B1 (en) 2015-12-09
MX2012010895A (es) 2013-02-15
DK2550286T3 (en) 2016-02-29
AU2016203986B2 (en) 2016-10-06
WO2011119604A1 (en) 2011-09-29
HRP20160168T1 (hr) 2016-03-25
JP2015063536A (ja) 2015-04-09
RU2650883C2 (ru) 2018-04-18
MY162411A (en) 2017-06-15
US8759500B2 (en) 2014-06-24
NZ602544A (en) 2014-11-28
EP3009442B1 (en) 2019-06-19
US20130018008A1 (en) 2013-01-17
CN103080122A (zh) 2013-05-01
IL222018B (en) 2019-05-30
EP2550286A1 (en) 2013-01-30
US20160244472A1 (en) 2016-08-25
AU2016203986A1 (en) 2016-06-30
CA2793884C (en) 2019-09-10

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