JP2013519636A5 - - Google Patents

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Publication number
JP2013519636A5
JP2013519636A5 JP2012552352A JP2012552352A JP2013519636A5 JP 2013519636 A5 JP2013519636 A5 JP 2013519636A5 JP 2012552352 A JP2012552352 A JP 2012552352A JP 2012552352 A JP2012552352 A JP 2012552352A JP 2013519636 A5 JP2013519636 A5 JP 2013519636A5
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JP
Japan
Prior art keywords
fviii
domain
linked
psa
fviii variant
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JP2012552352A
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English (en)
Japanese (ja)
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JP2013519636A (ja
JP5933457B2 (ja
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Priority claimed from PCT/EP2011/051723 external-priority patent/WO2011101267A1/en
Publication of JP2013519636A publication Critical patent/JP2013519636A/ja
Publication of JP2013519636A5 publication Critical patent/JP2013519636A5/ja
Application granted granted Critical
Publication of JP5933457B2 publication Critical patent/JP5933457B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2012552352A 2010-02-16 2011-02-07 コンジュゲートfviiiバリアント Expired - Fee Related JP5933457B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP10153718 2010-02-16
EP10153718.1 2010-02-16
US30560810P 2010-02-18 2010-02-18
US61/305,608 2010-02-18
PCT/EP2011/051723 WO2011101267A1 (en) 2010-02-16 2011-02-07 Conjugated fviii variants

Publications (3)

Publication Number Publication Date
JP2013519636A JP2013519636A (ja) 2013-05-30
JP2013519636A5 true JP2013519636A5 (enExample) 2014-03-27
JP5933457B2 JP5933457B2 (ja) 2016-06-08

Family

ID=42173354

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012553254A Expired - Fee Related JP5914363B2 (ja) 2010-02-16 2011-02-02 低減されたvwf結合を有する因子viii分子
JP2012552352A Expired - Fee Related JP5933457B2 (ja) 2010-02-16 2011-02-07 コンジュゲートfviiiバリアント

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2012553254A Expired - Fee Related JP5914363B2 (ja) 2010-02-16 2011-02-02 低減されたvwf結合を有する因子viii分子

Country Status (5)

Country Link
US (4) US20130040888A1 (enExample)
EP (2) EP2536753B1 (enExample)
JP (2) JP5914363B2 (enExample)
CN (3) CN105524164A (enExample)
WO (2) WO2011101242A1 (enExample)

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KR20170125941A (ko) 2015-03-06 2017-11-15 체에스엘 베링 리컴비넌트 퍼실리티 아게 개선된 반감기를 갖는 변형된 폰 빌레브란트 인자
AU2016301303B2 (en) 2015-08-03 2021-10-07 Bioverativ Therapeutics Inc. Factor IX fusion proteins and methods of making and using same
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EP3476860A4 (en) * 2016-06-24 2020-01-22 Mogam Institute for Biomedical Research Recombinant single-chain fviii and chemical conjugate thereof
EP3476937A4 (en) 2016-06-24 2019-12-04 Mogam Institute for Biomedical Research CHIMERIC PROTEIN WITH FVIII AND VWF FACTORS AND USE THEREOF
WO2018102743A1 (en) 2016-12-02 2018-06-07 Bioverativ Therapeutics Inc. Methods of treating hemophilic arthropathy using chimeric clotting factors
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US11299533B2 (en) * 2017-06-23 2022-04-12 Takeda Pharmaceutical Company Limited Purification of factor VIII subspecies
EP3441471A1 (en) 2017-08-08 2019-02-13 CEVEC Pharmaceuticals GmbH Use of constitutively active variants of growth factor receptors as selection makers for the generation of stable producer cell lines
SG11202008242XA (en) 2018-03-02 2020-09-29 Kodiak Sciences Inc Il-6 antibodies and fusion constructs and conjugates thereof
CN113039200B (zh) 2018-05-18 2023-07-25 郑州晟斯生物科技有限公司 改进的fviii融合蛋白及其应用
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