JP2013517761A5 - - Google Patents

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Publication number
JP2013517761A5
JP2013517761A5 JP2012549441A JP2012549441A JP2013517761A5 JP 2013517761 A5 JP2013517761 A5 JP 2013517761A5 JP 2012549441 A JP2012549441 A JP 2012549441A JP 2012549441 A JP2012549441 A JP 2012549441A JP 2013517761 A5 JP2013517761 A5 JP 2013517761A5
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JP
Japan
Prior art keywords
cell
antibody
polypeptide
antibody polypeptide
yarrowia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012549441A
Other languages
English (en)
Japanese (ja)
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JP2013517761A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2011/000227 external-priority patent/WO2011089527A1/en
Publication of JP2013517761A publication Critical patent/JP2013517761A/ja
Publication of JP2013517761A5 publication Critical patent/JP2013517761A5/ja
Pending legal-status Critical Current

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JP2012549441A 2010-01-21 2011-01-21 酵母細胞の表面上にポリペプチドをディスプレイするための方法および組成物 Pending JP2013517761A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29709310P 2010-01-21 2010-01-21
US61/297,093 2010-01-21
PCT/IB2011/000227 WO2011089527A1 (en) 2010-01-21 2011-01-21 Methods and compositions for displaying a poypeptide on a yeast cell surface

Publications (2)

Publication Number Publication Date
JP2013517761A JP2013517761A (ja) 2013-05-20
JP2013517761A5 true JP2013517761A5 (https=) 2014-03-13

Family

ID=44022829

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012549441A Pending JP2013517761A (ja) 2010-01-21 2011-01-21 酵母細胞の表面上にポリペプチドをディスプレイするための方法および組成物

Country Status (9)

Country Link
US (1) US20130096281A1 (https=)
EP (1) EP2526193A1 (https=)
JP (1) JP2013517761A (https=)
KR (1) KR20120118045A (https=)
CN (1) CN102803491A (https=)
BR (1) BR112012018163A2 (https=)
CA (1) CA2787677A1 (https=)
SG (1) SG182647A1 (https=)
WO (1) WO2011089527A1 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008120107A2 (en) 2007-04-03 2008-10-09 Oxyrane (Uk) Limited Glycosylation of molecules
US9598682B2 (en) 2009-09-29 2017-03-21 Vib Vzw Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose
US20130053550A1 (en) 2009-11-19 2013-02-28 Oxyrane Uk Limited Yeast strains producing mammalian-like complex n-glycans
WO2012042387A2 (en) 2010-09-29 2012-04-05 Oxyrane Uk Limited De-mannosylation of phosphorylated n-glycans
US9347050B2 (en) 2010-09-29 2016-05-24 Oxyrane Uk Limited Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated N-glycans and methods of facilitating mammalian cellular uptake of glycoproteins
EP2739733B1 (en) * 2011-08-03 2017-11-22 Texas Biomedical Research Insitute Nucleic acid compositions, methods and kits for rapid pairing of affinity agents
EP3628326B1 (en) 2012-03-15 2024-02-28 Oxyrane UK Limited Methods and materials for treatment of pompe's disease
MY191512A (en) * 2013-09-18 2022-06-28 Regeneron Pharma Histidine engineered light chain antibodies and genetically modified non-human animals for generating the same
CN113354744A (zh) * 2013-12-20 2021-09-07 弗雷德哈钦森癌症研究中心 带标签的嵌合效应分子及其受体
FR3028527A1 (fr) 2014-11-13 2016-05-20 Pivert Identification de facteurs de transcription de yarrowia lipolytica
WO2016075314A1 (fr) 2014-11-13 2016-05-19 Institut National De La Recherche Agronomique Identification de facteurs de transcription de yarrowia lipolytica affectant la production de proteines
US20160185633A1 (en) * 2014-12-30 2016-06-30 University Of Florida Research Foundation, Inc. Recovery of nutrients from water and wastewater by precipitation as struvite
EP3288570A4 (en) 2015-04-29 2018-11-21 Fred Hutchinson Cancer Research Center Modified stem cells and uses thereof
CN108779451A (zh) * 2016-01-08 2018-11-09 帝斯曼知识产权资产管理有限公司 解脂耶氏酵母的交配型转换
US10988759B2 (en) 2016-01-15 2021-04-27 University Of Washington High throughput protein-protein interaction screening in yeast liquid culture
CN106701606B (zh) * 2016-12-19 2021-03-26 广东利世康低碳科技有限公司 一种能降解利用餐厨废弃物的基因工程产朊假丝酵母及其构建方法
CN108085332B (zh) * 2017-12-27 2020-11-27 中国科学院青岛生物能源与过程研究所 一种细胞表面展示有豆壳过氧化物酶的重组酵母菌及其构建方法与应用
FR3081169B1 (fr) 2018-05-15 2020-06-19 Messenger Biopharma Substitution de la coiffe des arn messagers par deux sequences d'arn introduites a leur extremite 5'
IL298006B2 (en) * 2020-05-11 2024-10-01 A Alpha Bio Inc High-throughput screening methods to identify small molecule targets
IL298616B2 (en) 2020-06-01 2024-11-01 A Alpha Bio Inc Methods for characterizing and engineering protein-protein interactions
CN111996132A (zh) * 2020-07-21 2020-11-27 郑州大学 一种解脂耶氏酵母表面展示方法
WO2023051972A1 (en) 2021-09-29 2023-04-06 Miltenyi Biotec B.V. & Co. KG Method for the generation and selection of a producer cell
CN114606151B (zh) * 2022-04-27 2023-05-19 南京工业大学 一种表面展示β-半乳糖苷酶的重组毕赤酵母及构建方法和应用
CN115851460A (zh) * 2022-08-10 2023-03-28 丁辰 一种具有激活哺乳动物干细胞分化功能的菌株、组合物及其应用
CN115786387B (zh) * 2022-09-19 2024-02-13 苏州泓迅生物科技股份有限公司 一种通用型酵母细胞表面展示质粒载体及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6042828A (en) 1992-09-07 2000-03-28 Kyowa Hakko Kogyo Co., Ltd. Humanized antibodies to ganglioside GM2
US6300065B1 (en) * 1996-05-31 2001-10-09 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US6699658B1 (en) * 1996-05-31 2004-03-02 Board Of Trustees Of The University Of Illinois Yeast cell surface display of proteins and uses thereof
US7442772B2 (en) 1997-12-03 2008-10-28 Genentech, Inc. Antibodies to PRO361 polypeptide
WO2001042462A2 (en) 1999-12-08 2001-06-14 National University Of Singapore Phospholipase a2 inhibitory peptides from python reticulatus
DK1438400T3 (da) * 2001-10-01 2009-10-05 Dyax Corp Flerkædede eukaryote display-vektorer og anvendelser deraf
ES2327830T3 (es) 2002-03-29 2009-11-04 Schering Corporation Anticuerpos monoclonales humanos anti-interleuquina-5 y metodos y composiciones que los contienen.
CA2501422C (en) 2004-04-29 2014-08-12 University Of Rochester Lymphoid chemokines in the diagnosis, monitoring and treatment of autoimmune disease
US7431927B2 (en) 2005-03-24 2008-10-07 Epitomics, Inc. TNFα-neutralizing antibodies
CA2604917A1 (en) 2005-04-14 2007-01-25 Csir Recombinant yeasts for synthesizing epoxide hydrolases
US20110076752A1 (en) * 2007-02-09 2011-03-31 Medimmune, Llc Antibody library display by yeast cell plasma membrane

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