JP2013516427A5 - - Google Patents
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- JP2013516427A5 JP2013516427A5 JP2012547309A JP2012547309A JP2013516427A5 JP 2013516427 A5 JP2013516427 A5 JP 2013516427A5 JP 2012547309 A JP2012547309 A JP 2012547309A JP 2012547309 A JP2012547309 A JP 2012547309A JP 2013516427 A5 JP2013516427 A5 JP 2013516427A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- bbi
- protein
- product
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004169 proteins and genes Human genes 0.000 claims description 27
- 108090000623 proteins and genes Proteins 0.000 claims description 27
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 22
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 12
- 230000000694 effects Effects 0.000 claims description 10
- 230000002401 inhibitory effect Effects 0.000 claims description 10
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 claims description 9
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims description 9
- 239000002158 endotoxin Substances 0.000 claims description 8
- 108090000317 Chymotrypsin Proteins 0.000 claims description 5
- 101710137926 Chymotrypsin inhibitor Proteins 0.000 claims description 5
- 108090000631 Trypsin Proteins 0.000 claims description 5
- 102000004142 Trypsin Human genes 0.000 claims description 5
- 229940122618 Trypsin inhibitor Drugs 0.000 claims description 5
- 101710162629 Trypsin inhibitor Proteins 0.000 claims description 5
- 229960002376 chymotrypsin Drugs 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 239000012588 trypsin Substances 0.000 claims description 5
- 239000002753 trypsin inhibitor Substances 0.000 claims description 5
- 229940122644 Chymotrypsin inhibitor Drugs 0.000 claims description 4
- 239000003541 chymotrypsin inhibitor Substances 0.000 claims description 4
- 230000001575 pathological effect Effects 0.000 claims description 3
- 230000001737 promoting effect Effects 0.000 claims description 2
- 230000036559 skin health Effects 0.000 claims description 2
- 108091005804 Peptidases Proteins 0.000 claims 1
- 239000004365 Protease Substances 0.000 claims 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
- 229940121649 protein inhibitor Drugs 0.000 claims 1
- 239000012268 protein inhibitor Substances 0.000 claims 1
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29131209P | 2009-12-30 | 2009-12-30 | |
| US61/291,312 | 2009-12-30 | ||
| PCT/US2010/062553 WO2011082335A2 (en) | 2009-12-30 | 2010-12-30 | Purified bowman-birk protease inhibitor proteins isolated from a soy processing stream |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013516427A JP2013516427A (ja) | 2013-05-13 |
| JP2013516427A5 true JP2013516427A5 (enExample) | 2014-02-13 |
Family
ID=44226820
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547316A Pending JP2013516431A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
| JP2012547317A Pending JP2013516432A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームからＫｕｎｉｔｚトリプシンインヒビタータンパク質を回収する方法 |
| JP2012547309A Pending JP2013516427A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製ボーマン・バークプロテアーゼインヒビタープロテイン |
| JP2012547311A Pending JP2013516429A (ja) | 2009-12-30 | 2010-12-30 | ボーマン・バークインヒビタープロテインを大豆加工ストリームから回収する方法 |
| JP2015118467A Abandoned JP2015157873A (ja) | 2009-12-30 | 2015-06-11 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547316A Pending JP2013516431A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
| JP2012547317A Pending JP2013516432A (ja) | 2009-12-30 | 2010-12-30 | 大豆加工ストリームからＫｕｎｉｔｚトリプシンインヒビタータンパク質を回収する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012547311A Pending JP2013516429A (ja) | 2009-12-30 | 2010-12-30 | ボーマン・バークインヒビタープロテインを大豆加工ストリームから回収する方法 |
| JP2015118467A Abandoned JP2015157873A (ja) | 2009-12-30 | 2015-06-11 | 大豆加工ストリームから単離される精製Ｋｕｎｉｔｚトリプシンインヒビタータンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US20130023649A1 (enExample) |
| EP (5) | EP2519245A4 (enExample) |
| JP (5) | JP2013516431A (enExample) |
| CN (6) | CN102770147A (enExample) |
| BR (2) | BR112012016232A2 (enExample) |
| CA (2) | CA2785736A1 (enExample) |
| WO (5) | WO2011082359A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2504373C2 (ru) | 2008-03-26 | 2014-01-20 | ОРАМЕД Лтд. | Способы и композиции для перорального введения протеинов |
| WO2013002786A1 (en) * | 2011-06-29 | 2013-01-03 | Solae | Baked food compositions comprising soy whey proteins that have been isolated from processing streams |
| CN112755002A (zh) * | 2012-02-01 | 2021-05-07 | 奥拉姆德有限公司 | 含有蛋白酶抑制物的组合物、包含前者的组合物和用于产生和使用前者的方法 |
| BR112015001578A2 (pt) * | 2012-07-26 | 2017-07-04 | Solae Llc | agentes de formação de espuma, produto para os cuidados pessoais, produto industrial, produtos, equipamento e método para a fabricação de um produto |
| US20150272170A1 (en) * | 2012-07-26 | 2015-10-01 | Solae, Llc | Foaming agent for use in food compositions |
| JP2015532612A (ja) * | 2012-07-26 | 2015-11-12 | ソレイ リミテッド ライアビリティ カンパニー | 食品組成物で使用するための乳化剤 |
| CN104902960A (zh) * | 2012-07-26 | 2015-09-09 | 索莱有限责任公司 | 用于个人护理产品和工业产品中的乳化剂 |
| BR112015008661A2 (pt) | 2012-10-23 | 2017-07-04 | Upfront Chromatography As | processos de separação para proteína de soja |
| EP2941267B1 (en) | 2013-01-03 | 2022-11-16 | Oramed Ltd. | Compositions for use in treating nafld |
| FR3001362B1 (fr) | 2013-01-31 | 2015-07-10 | Roquette Freres | Procede de fractionnement des solubles de pois, fractions obtenues et leur valorisation |
| CN103392907B (zh) * | 2013-06-08 | 2014-12-17 | 东北农业大学 | 酶法修饰改善乳清蛋白纳米纤维聚合量的方法 |
| WO2015101435A1 (en) * | 2013-12-30 | 2015-07-09 | Koninklijke Philips N.V. | A method of making soymilk |
| EP3099187B1 (en) | 2014-01-29 | 2018-06-06 | Upfront Chromatography A/S | Novel separation processes for pea protein |
| CN103933548A (zh) * | 2014-04-17 | 2014-07-23 | 中国药科大学 | 露那辛多肽在防治白内障药物中的应用 |
| US11291221B2 (en) | 2015-10-30 | 2022-04-05 | Beth Israel Deaconess Medical Center, Inc. | Methods for determination of bioactivity, quantity, removal, or inactivation of cereal amylase trypsin inhibitors in cereals, flours, plants, and complex foods |
| US10858390B2 (en) * | 2016-09-02 | 2020-12-08 | Cem Corporation | Use of excess carbodiimide for peptide synthesis at elevated temperatures |
| US12376607B2 (en) | 2017-03-31 | 2025-08-05 | J.R. Simplot Company | Potato protein powders |
| CN107488226A (zh) * | 2017-09-06 | 2017-12-19 | 成都晟博源生物工程有限公司 | 一种大豆胰蛋白酶抑制剂的提取方法 |
| CN110872140B (zh) * | 2018-09-03 | 2022-06-21 | 中国石油化工股份有限公司 | 危化品分离回收系统 |
| CN110104754B (zh) * | 2019-04-03 | 2022-03-29 | 江苏农林职业技术学院 | 一种豆制品废水废渣处理甲基橙染料废水的方法 |
| CN110551209A (zh) * | 2019-08-27 | 2019-12-10 | 合肥天汇孵化科技有限公司 | 一种基于大豆深加工废液以豆清水为原料粗提sbti蛋白工艺 |
| WO2021099529A1 (en) * | 2019-11-20 | 2021-05-27 | Csl Behring Ag | Method for extracting a protein from a precipitate and method for precipitating impurities |
| AU2021227964A1 (en) * | 2020-02-26 | 2022-09-22 | Eat Just, Inc. | Pulse protein isolation by ultrafiltration |
| JP2023528657A (ja) * | 2020-06-12 | 2023-07-05 | ビーエーエスエフ ソシエタス・ヨーロピア | 発酵ブロスの改善された脱塩及び例えばオリゴ糖のファインケミカルの精製 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4368151A (en) * | 1981-08-10 | 1983-01-11 | A. E. Staley Manufacturing Company | 7S And 11S vegetable protein fractionation and isolation |
| US5288856A (en) * | 1986-11-20 | 1994-02-22 | Pierre Amiguet | Method of isolating acid-stable, biologically active proteins |
| US4808314A (en) * | 1987-09-18 | 1989-02-28 | Scripps Clinic And Research Foundation | Method for reducing bacterial endotoxin contamination in solutions of macromolecules |
| TR24186A (tr) * | 1988-04-11 | 1991-05-30 | Monsanto Co | Hasere zehirlerinin etkinligini arttirmak icin yoentem |
| US5250515A (en) * | 1988-04-11 | 1993-10-05 | Monsanto Company | Method for improving the efficacy of insect toxins |
| JPH06145198A (ja) * | 1992-03-30 | 1994-05-24 | Shokuhin Sangyo High Separeeshiyon Syst Gijutsu Kenkyu Kumiai | 大豆トリプシンインヒビターの製造方法 |
| DK46793D0 (da) * | 1993-04-26 | 1993-04-26 | Novo Nordisk As | Enzym |
| JPH1066572A (ja) * | 1996-08-29 | 1998-03-10 | Showa Sangyo Co Ltd | 高純度の大豆トリプシンインヒビターの製造方法 |
| US6313273B1 (en) * | 1999-08-25 | 2001-11-06 | Abbott Laboratories | Soy proteins and methods for their production |
| US6787173B2 (en) * | 2000-11-30 | 2004-09-07 | Kraft Foods Holdings, Inc. | Method of deflavoring soy-derived materials |
| US7175869B2 (en) * | 2000-11-30 | 2007-02-13 | Kraft Foods Holdings, Inc. | Method of deflavoring soy-derived materials using electrodialysis |
| CN1150831C (zh) * | 2001-01-19 | 2004-05-26 | 北京中联捷思科技发展有限公司 | 超滤提取大豆乳清蛋白的方法 |
| US6927322B2 (en) * | 2001-03-30 | 2005-08-09 | Cornell Research Foundation, Inc. | Cabbage proteinase inhibitor gene confers resistance against plant pests |
| US7214394B2 (en) * | 2002-05-31 | 2007-05-08 | Archer-Daniels-Midland Company | Policosanol compositions, extraction from novel sources, and uses thereof |
| CN100506062C (zh) * | 2002-08-28 | 2009-07-01 | 不二制油株式会社 | 酸性大豆蛋白质凝胶食物及其生产方法 |
| JPWO2004104036A1 (ja) * | 2003-05-21 | 2006-10-26 | 不二製油株式会社 | 大豆ホエー蛋白及び大豆ホエー蛋白分解物の製造法 |
| US20070277269A1 (en) * | 2006-04-17 | 2007-11-29 | Ceres, Inc. | Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics |
| EP1679971A2 (en) * | 2003-11-05 | 2006-07-19 | Kerry Group Services International Limited | Acid-stable soy protein and fortified food or beverage |
| ATE513917T1 (de) * | 2003-11-06 | 2011-07-15 | Genencor Int | Bakterielle expression von proteaseinhibitoren und varianten davon |
| JP4834554B2 (ja) * | 2003-11-06 | 2011-12-14 | ジェネンコー・インターナショナル・インク | 糸状菌におけるプロテアーゼ抑制剤及びその変異体の発現 |
| CN1615722A (zh) * | 2003-11-14 | 2005-05-18 | 哈高科大豆食品有限责任公司 | 超滤膜分离技术制备大豆分离蛋白的方法 |
| EP1738654A4 (en) * | 2004-02-26 | 2009-07-22 | Fuji Oil Co Ltd | SOY PROTEIN (S) SOLUTION AND GEL |
| US20070160697A1 (en) * | 2004-02-27 | 2007-07-12 | Hiroshi Kobayashi | Cancer metastasis inhibitory composition |
| US20060057275A1 (en) * | 2004-09-16 | 2006-03-16 | Shaowen Wu | Process for the preparation of glycinin-rich and beta-conglycinin-rich protein fractions |
| CN101278051B (zh) * | 2005-05-05 | 2011-10-05 | 金克克国际有限公司 | 个人护理组合物及其使用方法 |
| US20070054031A1 (en) * | 2005-09-02 | 2007-03-08 | Keshun Liu | Methods of extracting, concentrating and fractionating proteins and other chemical components |
| TWI257723B (en) * | 2005-09-15 | 2006-07-01 | Epitech Technology Corp | Vertical light-emitting diode and method for manufacturing the same |
| US20080182002A1 (en) * | 2007-01-26 | 2008-07-31 | Solae, Llc | Processes for Removing Bitter Components from Soy Protein Isolates |
| BRPI0811788A2 (pt) * | 2007-07-03 | 2014-10-07 | Solae Llc | Composição de proteína vegetal, processo para a fabricação de uma composição de proteína vegetal e produto alimentício |
| CN101367018A (zh) * | 2007-09-13 | 2009-02-18 | 中国海洋大学 | 壳聚糖树脂固定化酶纯化大豆乳清废水中胰蛋白酶抑制剂的工艺 |
| RU2509776C2 (ru) * | 2008-10-15 | 2014-03-20 | ДАНИСКО ЮЭс ИНК. | МОДИФИЦИРОВАННЫЕ ВАРИАНТЫ ИНГИБИТОРОВ ПРОТЕАЗ Bowman Birk |
-
2010
- 2010-12-30 US US13/519,842 patent/US20130023649A1/en not_active Abandoned
- 2010-12-30 US US13/519,840 patent/US20120302736A1/en not_active Abandoned
- 2010-12-30 WO PCT/US2010/062592 patent/WO2011082359A1/en not_active Ceased
- 2010-12-30 CA CA2785736A patent/CA2785736A1/en not_active Abandoned
- 2010-12-30 EP EP10841759.3A patent/EP2519245A4/en not_active Withdrawn
- 2010-12-30 JP JP2012547316A patent/JP2013516431A/ja active Pending
- 2010-12-30 WO PCT/US2010/062591 patent/WO2011082358A1/en not_active Ceased
- 2010-12-30 JP JP2012547317A patent/JP2013516432A/ja active Pending
- 2010-12-30 US US13/519,829 patent/US20120329993A1/en not_active Abandoned
- 2010-12-30 WO PCT/US2010/062594 patent/WO2011082360A1/en not_active Ceased
- 2010-12-30 WO PCT/US2010/062556 patent/WO2011082338A1/en not_active Ceased
- 2010-12-30 EP EP10841760.1A patent/EP2785730A1/en not_active Withdrawn
- 2010-12-30 BR BR112012016232A patent/BR112012016232A2/pt not_active IP Right Cessation
- 2010-12-30 JP JP2012547309A patent/JP2013516427A/ja active Pending
- 2010-12-30 EP EP10841758.5A patent/EP2519117A4/en not_active Withdrawn
- 2010-12-30 CN CN2010800642291A patent/CN102770147A/zh active Pending
- 2010-12-30 BR BR112012016225A patent/BR112012016225A2/pt active Search and Examination
- 2010-12-30 CN CN201080064855.0A patent/CN102781255B/zh not_active Expired - Fee Related
- 2010-12-30 EP EP10841743.7A patent/EP2519535A4/en not_active Withdrawn
- 2010-12-30 CN CN201080064208XA patent/CN102762584A/zh active Pending
- 2010-12-30 US US13/519,848 patent/US20120289683A1/en not_active Abandoned
- 2010-12-30 CA CA2785599A patent/CA2785599A1/en not_active Abandoned
- 2010-12-30 WO PCT/US2010/062553 patent/WO2011082335A2/en not_active Ceased
- 2010-12-30 US US13/519,832 patent/US20130023480A1/en not_active Abandoned
- 2010-12-30 CN CN2010800648423A patent/CN102781459A/zh active Pending
- 2010-12-30 CN CN201410168443.1A patent/CN103988973A/zh active Pending
- 2010-12-30 EP EP10841740.3A patent/EP2519251A4/en not_active Withdrawn
- 2010-12-30 JP JP2012547311A patent/JP2013516429A/ja active Pending
- 2010-12-30 CN CN2010800648368A patent/CN102770439A/zh active Pending
-
2015
- 2015-06-11 JP JP2015118467A patent/JP2015157873A/ja not_active Abandoned
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