JP2013515057A5 - - Google Patents
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- Publication number
- JP2013515057A5 JP2013515057A5 JP2012546035A JP2012546035A JP2013515057A5 JP 2013515057 A5 JP2013515057 A5 JP 2013515057A5 JP 2012546035 A JP2012546035 A JP 2012546035A JP 2012546035 A JP2012546035 A JP 2012546035A JP 2013515057 A5 JP2013515057 A5 JP 2013515057A5
- Authority
- JP
- Japan
- Prior art keywords
- cys
- asn
- oxyntomodulin peptide
- gln
- leu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101800001388 Oxyntomodulin Proteins 0.000 claims 13
- 239000003814 drug Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 208000008589 Obesity Diseases 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 235000020824 obesity Nutrition 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 1
- 150000003573 thiols Chemical class 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28888809P | 2009-12-22 | 2009-12-22 | |
| US61/288,888 | 2009-12-22 | ||
| US35257610P | 2010-06-08 | 2010-06-08 | |
| US61/352,576 | 2010-06-08 | ||
| PCT/US2010/060390 WO2011087672A1 (en) | 2009-12-22 | 2010-12-15 | Oxyntomodulin peptide analogue |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013515057A JP2013515057A (ja) | 2013-05-02 |
| JP2013515057A5 true JP2013515057A5 (https=) | 2014-02-06 |
| JP5717759B2 JP5717759B2 (ja) | 2015-05-13 |
Family
ID=43587001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012546035A Active JP5717759B2 (ja) | 2009-12-22 | 2010-12-15 | オキシントモジュリンペプチドアナログ |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US8367607B2 (https=) |
| EP (1) | EP2515928B1 (https=) |
| JP (1) | JP5717759B2 (https=) |
| KR (1) | KR101399671B1 (https=) |
| CN (1) | CN102740873B (https=) |
| AR (1) | AR079345A1 (https=) |
| AU (1) | AU2010341651B2 (https=) |
| BR (1) | BR112012017348B1 (https=) |
| CA (1) | CA2784671C (https=) |
| CL (1) | CL2012001686A1 (https=) |
| CO (1) | CO6551738A2 (https=) |
| CR (1) | CR20120338A (https=) |
| DK (1) | DK2515928T3 (https=) |
| DO (1) | DOP2012000176A (https=) |
| EA (1) | EA022820B1 (https=) |
| ES (1) | ES2486675T3 (https=) |
| HN (1) | HN2012001321A (https=) |
| HR (1) | HRP20140616T1 (https=) |
| IL (1) | IL220161B (https=) |
| JO (1) | JO2976B1 (https=) |
| MA (1) | MA33825B1 (https=) |
| MX (1) | MX2012007438A (https=) |
| MY (1) | MY160773A (https=) |
| NZ (1) | NZ600731A (https=) |
| PE (1) | PE20121393A1 (https=) |
| PH (1) | PH12012501263B1 (https=) |
| PL (1) | PL2515928T3 (https=) |
| PT (1) | PT2515928E (https=) |
| RS (1) | RS53505B1 (https=) |
| SG (1) | SG181430A1 (https=) |
| SI (1) | SI2515928T1 (https=) |
| TN (1) | TN2012000302A1 (https=) |
| TW (1) | TWI423812B (https=) |
| WO (1) | WO2011087672A1 (https=) |
Families Citing this family (82)
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| US8048849B2 (en) | 2006-02-03 | 2011-11-01 | Modigene, Inc. | Long-acting polypeptides and methods of producing same |
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| EP2158214B1 (en) | 2007-06-15 | 2011-08-17 | Zealand Pharma A/S | Glucagon analogues |
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