JP2013511975A5 - - Google Patents
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- Publication number
- JP2013511975A5 JP2013511975A5 JP2012540503A JP2012540503A JP2013511975A5 JP 2013511975 A5 JP2013511975 A5 JP 2013511975A5 JP 2012540503 A JP2012540503 A JP 2012540503A JP 2012540503 A JP2012540503 A JP 2012540503A JP 2013511975 A5 JP2013511975 A5 JP 2013511975A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- disease virus
- newcastle disease
- virus clone
- clone according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 241000711404 Avian avulavirus 1 Species 0.000 claims 13
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 201000011510 cancer Diseases 0.000 claims 10
- 239000003814 drug Substances 0.000 claims 9
- 238000004519 manufacturing process Methods 0.000 claims 7
- 229940124597 therapeutic agent Drugs 0.000 claims 7
- 238000001959 radiotherapy Methods 0.000 claims 5
- 102000014150 Interferons Human genes 0.000 claims 2
- 108010050904 Interferons Proteins 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 238000002512 chemotherapy Methods 0.000 claims 2
- 229940127089 cytotoxic agent Drugs 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 229940079322 interferon Drugs 0.000 claims 2
- 208000032839 leukemia Diseases 0.000 claims 2
- 230000001613 neoplastic effect Effects 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 claims 1
- 208000009137 Behcet syndrome Diseases 0.000 claims 1
- 206010004593 Bile duct cancer Diseases 0.000 claims 1
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010007275 Carcinoid tumour Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 claims 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 claims 1
- 208000007766 Kaposi sarcoma Diseases 0.000 claims 1
- 208000019693 Lung disease Diseases 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- 208000034578 Multiple myelomas Diseases 0.000 claims 1
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 claims 1
- 208000001132 Osteoporosis Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 206010067362 Radiation necrosis Diseases 0.000 claims 1
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 1
- 208000007660 Residual Neoplasm Diseases 0.000 claims 1
- 201000003176 Severe Acute Respiratory Syndrome Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 208000002399 aphthous stomatitis Diseases 0.000 claims 1
- 230000001363 autoimmune Effects 0.000 claims 1
- 208000026900 bile duct neoplasm Diseases 0.000 claims 1
- 208000002458 carcinoid tumor Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 230000030833 cell death Effects 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 208000006990 cholangiocarcinoma Diseases 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 210000002768 hair cell Anatomy 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000003211 malignant effect Effects 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 208000015347 renal cell adenocarcinoma Diseases 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 229940126585 therapeutic drug Drugs 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28315409P | 2009-11-30 | 2009-11-30 | |
| EP09075536.4 | 2009-11-30 | ||
| EP09075536A EP2327764B1 (en) | 2009-11-30 | 2009-11-30 | New clone of Newcastle disease virus, its manufacture and its application in the medical treatment of cancer |
| US61/283,154 | 2009-11-30 | ||
| PCT/IB2010/002227 WO2011064630A1 (en) | 2009-11-30 | 2010-08-13 | New clone of newcastle disease virus, its manufacture and its application in the medical treatment of cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013511975A JP2013511975A (ja) | 2013-04-11 |
| JP2013511975A5 true JP2013511975A5 (enExample) | 2013-10-03 |
| JP5807788B2 JP5807788B2 (ja) | 2015-11-10 |
Family
ID=41581942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540503A Expired - Fee Related JP5807788B2 (ja) | 2009-11-30 | 2010-08-13 | ニューカッスル病ウイルスの新規クローン、その作製及び癌治療への応用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8377450B2 (enExample) |
| EP (2) | EP2327764B1 (enExample) |
| JP (1) | JP5807788B2 (enExample) |
| KR (1) | KR20120106741A (enExample) |
| CN (1) | CN102803477B (enExample) |
| AT (1) | ATE539148T1 (enExample) |
| CA (1) | CA2782189C (enExample) |
| DK (1) | DK2327764T3 (enExample) |
| ES (1) | ES2380289T3 (enExample) |
| IL (1) | IL207623A (enExample) |
| WO (1) | WO2011064630A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2327764B1 (en) * | 2009-11-30 | 2011-12-28 | United Cancer Research Institute | New clone of Newcastle disease virus, its manufacture and its application in the medical treatment of cancer |
| KR101636683B1 (ko) * | 2013-08-28 | 2016-07-07 | 주식회사 바이오포아 | 내열성이 향상된 뉴캣슬병 바이러스 ｂｐ ａｃｎｄｍ |
| KR101653401B1 (ko) * | 2013-08-28 | 2016-09-12 | 주식회사 바이오포아 | 내열성이 향상된 뉴캣슬병 바이러스 ｂｐ ａｃｎｄ |
| JP6731405B2 (ja) * | 2014-11-07 | 2020-07-29 | ケース ウエスタン リザーブ ユニバーシティ | ウイルス粒子を用いた癌免疫療法 |
| RU2644676C1 (ru) * | 2016-10-18 | 2018-02-13 | Общество с ограниченной ответственностью "Витагор" (ООО "ВИТАГОР") | Штамм вируса болезни Ньюкасла NDVH-2 для изучения возможности разработки на его основе вирусного онколитического препарата |
| KR101964610B1 (ko) * | 2017-03-13 | 2019-04-03 | 대한민국 | 신규한 종양용해성 바이러스 및 이의 용도 |
| EP3552608A1 (en) * | 2018-04-09 | 2019-10-16 | Rapo Yerape B.H. Ltd | Increased activity of oncoloytic newcastle disease virus |
| EP3844268A1 (en) * | 2018-08-31 | 2021-07-07 | Thaller, Arno | Novel recombinant newcastle disease virus |
| CN113913553B (zh) * | 2021-10-15 | 2024-08-27 | 广西壮族自治区兽医研究所 | 基因ⅻ型新城疫病毒荧光定量rt-pcr检测试剂盒及其引物对 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU197846B (en) | 1984-07-02 | 1989-06-28 | Laszlo Csatary | Process for producing therapeutic composition suitable for treating virus infections |
| HU197517B (en) | 1984-07-30 | 1989-04-28 | Laszlo Csatary | Process for production of terapeutical composition applicable against virus infection |
| DE3806565A1 (de) | 1988-03-01 | 1989-09-14 | Deutsches Krebsforsch | Virusmodifizierte tumorvakzinen fuer die immuntherapie von tumormetastasen |
| US5215745A (en) * | 1988-04-27 | 1993-06-01 | United Cancer Research Institute | Method for treating viral diseases with attenuated virus |
| US5124148A (en) * | 1988-04-27 | 1992-06-23 | United Cancer Research Institute | Method for treating viral diseases with attenuated virus |
| HU203983B (en) | 1988-12-05 | 1991-11-28 | Mta Allatorvostudomanyi Kutato | Process for producing living vaccine against fowlpox |
| WO1993018790A1 (en) | 1992-03-24 | 1993-09-30 | Csatary Laszlo K | Vaccine containing live virus for therapy of viral diseases and malignancies |
| US5602023A (en) * | 1992-03-24 | 1997-02-11 | Csatary; Laszlo K. | Pharmaceutical product containing live, stabilized virus for the therapy of viral and malignant diseases and process for preparing the same |
| FR2701580B1 (fr) | 1993-02-10 | 1995-03-24 | Bull Sa | Procédé d'administration d'applications avec des protocoles standards. |
| PT1486211E (pt) | 1993-04-30 | 2009-02-02 | Wellstat Biologics Corp | Composições para tratamento do cancro utilizando vírus |
| JPH08116976A (ja) | 1994-10-20 | 1996-05-14 | Chemo Sero Therapeut Res Inst | 免疫用核酸調製物およびこれを用いた免疫方法 |
| DE69632235T2 (de) | 1995-10-18 | 2004-08-26 | Akzo Nobel N.V. | Newcastle-Krankheitsvirus-Kombinationsimpfstoff |
| FR2750866B1 (fr) * | 1996-06-27 | 1998-11-27 | Rhone Merieux | Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire |
| NZ518945A (en) | 1997-10-09 | 2007-03-30 | Wellstat Biologics Corp | Treatment of neoplasms with viruses |
| EP0974660A1 (en) | 1998-06-19 | 2000-01-26 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Newcastle disease virus infectious clones, vaccines and diagnostic assays |
| US6146642A (en) | 1998-09-14 | 2000-11-14 | Mount Sinai School Of Medicine, Of The City University Of New York | Recombinant new castle disease virus RNA expression systems and vaccines |
| AU4246900A (en) | 1999-04-15 | 2000-11-02 | Pro-Virus, Inc. | Treatment of neoplasms with viruses |
| AU4971500A (en) | 1999-05-05 | 2000-11-21 | University Of Maryland | Production of novel newcastle disease virus strains from cdnas and improved liveattenuated newcastle disease vaccines |
| WO2000077218A1 (en) | 1999-06-10 | 2000-12-21 | Agricultural Research Council | Vaccine for newcastle disease virus |
| CA2414396A1 (en) | 2000-06-26 | 2002-01-03 | The United States Of America, As Represented By The Secretary Of Agricul Ture | Production of vaccines using transgenic plants |
| WO2002000233A2 (en) | 2000-06-26 | 2002-01-03 | Wellstat Biologics Corporation | Purging of cells using viruses |
| MXPA03003700A (es) | 2000-11-02 | 2004-05-04 | Akzo Nobel Nv | Mutante de nucleoproteina recombinante de virus de enfermedad de newcastle en la forma de una vacuna marcadora. |
| IL145397A0 (en) | 2001-09-12 | 2002-06-30 | Yissum Res Dev Co | Compositions and methods for treatment of cancer |
| WO2005113013A2 (en) | 2004-05-20 | 2005-12-01 | Theravir Management L.P. | Compositions of ndv and methods of use thereof for treatment of cancer |
| RU2314830C2 (ru) | 2002-06-21 | 2008-01-20 | Веллстат Байолоджикс Корпорейшн | Введение терапевтических вирусов |
| JP2005536538A (ja) * | 2002-08-23 | 2005-12-02 | シェーリング コーポレイション | 薬学的組成物 |
| EP1578451A4 (en) | 2002-11-05 | 2007-01-24 | Wellstat Biologics Corp | TREATMENT OF CARCINOID TUMORS WITH THERAPEUTIC VIRUSES |
| NZ543058A (en) | 2003-03-24 | 2008-04-30 | Wellstat Biologics Corp | Newcastle disease virus administration |
| NZ543056A (en) | 2003-03-24 | 2008-04-30 | Wellstat Biologics Corp | Newcastle disease virus comprising a plurality of doses for treating a mammalian subject having a tumour |
| US20060018836A1 (en) | 2003-11-25 | 2006-01-26 | United Cancer Research Institute | Method for treating human tumor cells with a newcastle disease virus strain having a p53 independent oncolytic effect |
| US20060018884A1 (en) * | 2003-11-25 | 2006-01-26 | United Cancer Research Institute | Method for treating human tumor cells with a newcastle disease virus strain and a chemotherapeutic agent |
| NZ550430A (en) | 2004-04-27 | 2009-06-26 | Wellstat Biologics Corp | Cancer treatment using viruses and camptothecins |
| NZ581958A (en) | 2004-11-12 | 2011-01-28 | Bayer Schering Pharma Ag | Recombinant newcastle disease virus comprising a transgene encoding a prodrug-converting enzyme or protease for use in the treatment of cancer |
| MX2007015407A (es) | 2005-07-14 | 2008-02-19 | Wellstat Biologics Corp | Tratamiento del cancer utilizando virus, fluoropirimidinas y camptotecinas. |
| CN1772886A (zh) | 2005-09-02 | 2006-05-17 | 中国农业科学院哈尔滨兽医研究所 | 表达传染性法氏囊病毒VP2基因的重组新城疫LaSota弱毒疫苗株 |
| PT2529747T (pt) | 2005-12-02 | 2018-05-09 | Icahn School Med Mount Sinai | Vírus da doença de newcastle quiméricos que apresentam proteínas de superfície não nativas e suas utilizações |
| KR100801180B1 (ko) | 2006-09-26 | 2008-02-05 | 주식회사 고려비엔피 | 약독화된 재조합 뉴캐슬병 바이러스 및 이를 함유하는뉴캐슬병 백신 |
| EP2091972B1 (en) | 2006-11-27 | 2016-01-13 | Schirrmacher, Dr., Volker | Multi-modal cancer therapy using viral hitch-hiking |
| WO2008140621A2 (en) * | 2006-12-21 | 2008-11-20 | Mount Sinai School Of Medicine Of New York University | Transgenic oncolytic viruses and uses thereof |
| CN101205544B (zh) * | 2007-08-07 | 2010-12-08 | 中国人民解放军第四军医大学 | 肿瘤靶向性重组新城疫病毒及其构建方法 |
| EP2327764B1 (en) * | 2009-11-30 | 2011-12-28 | United Cancer Research Institute | New clone of Newcastle disease virus, its manufacture and its application in the medical treatment of cancer |
-
2009
- 2009-11-30 EP EP09075536A patent/EP2327764B1/en active Active
- 2009-11-30 AT AT09075536T patent/ATE539148T1/de active
- 2009-11-30 ES ES09075536T patent/ES2380289T3/es active Active
- 2009-11-30 DK DK09075536.4T patent/DK2327764T3/da active
-
2010
- 2010-08-13 KR KR1020127013900A patent/KR20120106741A/ko not_active Ceased
- 2010-08-13 US US12/806,494 patent/US8377450B2/en not_active Expired - Fee Related
- 2010-08-13 JP JP2012540503A patent/JP5807788B2/ja not_active Expired - Fee Related
- 2010-08-13 CA CA2782189A patent/CA2782189C/en active Active
- 2010-08-13 CN CN201080054157.2A patent/CN102803477B/zh not_active Expired - Fee Related
- 2010-08-13 EP EP10768541A patent/EP2507366A1/en not_active Withdrawn
- 2010-08-13 WO PCT/IB2010/002227 patent/WO2011064630A1/en not_active Ceased
- 2010-08-15 IL IL207623A patent/IL207623A/en active IP Right Grant
-
2013
- 2013-01-14 US US13/741,024 patent/US20140030229A1/en not_active Abandoned
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