JP2013511272A - 哺乳類様複合ｎ−グリカンを生成する酵母株 - Google Patents

哺乳類様複合ｎ−グリカンを生成する酵母株 Download PDF

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JP2013511272A
JP2013511272A JP2012539436A JP2012539436A JP2013511272A JP 2013511272 A JP2013511272 A JP 2013511272A JP 2012539436 A JP2012539436 A JP 2012539436A JP 2012539436 A JP2012539436 A JP 2012539436A JP 2013511272 A JP2013511272 A JP 2013511272A
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glcnac
nucleic acid
protein
cell
man
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JP2013511272A5 (OSRAM
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スティーブン クリスチャン ヨゼフ ヘイセンス，
ヴァウテル フェルフェケン，
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オキシレイン ユーケー リミテッド
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    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01084—Glucan 1,3-alpha-glucosidase (3.2.1.84), i.e. mutanase
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    • C12Y302/01114—Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (3.2.1.114)

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JP2012539436A 2009-11-19 2010-11-19 哺乳類様複合ｎ−グリカンを生成する酵母株 Pending JP2013511272A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26282809P 2009-11-19 2009-11-19
US61/262,828 2009-11-19
PCT/IB2010/003154 WO2011061629A2 (en) 2009-11-19 2010-11-19 Yeast strains producing mammalian-like complex n-glycans

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JP2013511272A true JP2013511272A (ja) 2013-04-04
JP2013511272A5 JP2013511272A5 (OSRAM) 2014-01-09

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US (3) US20130053550A1 (OSRAM)
EP (1) EP2501805B1 (OSRAM)
JP (1) JP2013511272A (OSRAM)
KR (1) KR20130055555A (OSRAM)
CN (1) CN102834509A (OSRAM)
BR (1) BR112012011980A2 (OSRAM)
CA (1) CA2781240A1 (OSRAM)
DK (1) DK2501805T3 (OSRAM)
WO (1) WO2011061629A2 (OSRAM)

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BR112012011980A2 (pt) 2009-11-19 2021-09-08 Oxyrane Uk Limited Métodos de produzir células transformadas de yarrowia lipolytica e proteínas-alvocompreendendo n-glicanos, células transformadas de yarrowia lipolytica e suas culturas, bem como composição compreendendo glicoproteínas
EP2622089B1 (en) 2010-09-29 2023-11-01 Oxyrane UK Limited De-mannosylation of phosphorylated n-glycans
JP6151183B2 (ja) 2010-09-29 2017-06-21 オキシレイン ユーケー リミテッド マンノース−１−ホスホ−６−マンノース結合からキャップを外すことおよびリン酸化ｎ−グリカンを脱マンノシル化することができるマンノシダーゼならびに哺乳動物細胞による糖タンパク質の取り込みを促進する方法
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PL2991683T3 (pl) 2013-05-02 2020-03-31 Glykos Finland Oy Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiem
US9987373B2 (en) 2013-10-14 2018-06-05 Synaffix B.V. Modified glycoprotein, protein-conjugate and process for the preparation thereof
CN113151319A (zh) 2014-02-24 2021-07-23 银杏生物制品公司 二酰基甘油酰基转移酶(dga1)多核苷酸，和通过异源dga1的超量表达增加酵母细胞脂质生产的方法
CN108064266A (zh) 2014-07-21 2018-05-22 格利科斯芬兰公司 在丝状真菌中具有哺乳动物样n-聚糖的糖蛋白的制备
JP6912781B2 (ja) * 2016-05-03 2021-08-04 ブイアイビー ブイゼットダブリュＶｉｂ Ｖｚｗ 操作された真菌宿主に由来する複合グリカンを産生するための手段および方法
EP3784701A4 (en) 2018-04-24 2022-06-08 National Research Council of Canada THERAPEUTIC COMPOUNDS CROSSING THE BLOOD-BRAIN BARRIER AND THEIR USES
WO2020060948A1 (en) 2018-09-17 2020-03-26 Levadura Biotechnology, Inc. Production of cannabinoids in yeast using a fatty acid feedstock
KR102167388B1 (ko) * 2020-01-15 2020-10-19 코스맥스 주식회사 신규 로도스포리디움 토룰로이데스 균주 및 그 균주 배양액을 포함하는 화장료 조성물
CN116042562B (zh) * 2022-03-11 2023-10-20 山东恒鲁生物科技有限公司 重组酵母菌及其应用

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