JP2013508282A - ウイルス感染のための併用療法処置 - Google Patents

ウイルス感染のための併用療法処置 Download PDF

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Publication number
JP2013508282A
JP2013508282A JP2012534324A JP2012534324A JP2013508282A JP 2013508282 A JP2013508282 A JP 2013508282A JP 2012534324 A JP2012534324 A JP 2012534324A JP 2012534324 A JP2012534324 A JP 2012534324A JP 2013508282 A JP2013508282 A JP 2013508282A
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antiviral agent
receptor agonist
hydroxy
administered
hydroxyl
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Japanese (ja)
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JP2013508282A5 (enExample
Inventor
ジェイ.ギルフォード ウィリアム
エイチ.フォールズ ダリル
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ジェンムス ファーマ インコーポレイティド
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Publication of JP2013508282A5 publication Critical patent/JP2013508282A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41661,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012534324A 2009-10-14 2010-10-13 ウイルス感染のための併用療法処置 Pending JP2013508282A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25156109P 2009-10-14 2009-10-14
US61/251,561 2009-10-14
PCT/US2010/052506 WO2011047048A1 (en) 2009-10-14 2010-10-13 Combination therapy treatment for viral infections

Publications (2)

Publication Number Publication Date
JP2013508282A true JP2013508282A (ja) 2013-03-07
JP2013508282A5 JP2013508282A5 (enExample) 2013-12-05

Family

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JP2012534324A Pending JP2013508282A (ja) 2009-10-14 2010-10-13 ウイルス感染のための併用療法処置

Country Status (9)

Country Link
US (2) US20120190637A1 (enExample)
EP (1) EP2488168A1 (enExample)
JP (1) JP2013508282A (enExample)
KR (1) KR20120093955A (enExample)
CN (1) CN102655859A (enExample)
BR (1) BR112012008959A2 (enExample)
CA (1) CA2777384A1 (enExample)
NZ (1) NZ599128A (enExample)
WO (1) WO2011047048A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020516634A (ja) * 2017-04-12 2020-06-11 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated インフルエンザウイルス感染の処置方法および併用療法
JP2021116296A (ja) * 2020-01-21 2021-08-10 アカデミー オブ ミリタリー メディカル サイエンシズ コロナウイルス感染の治療におけるファビピラビルの使用
WO2021221111A1 (ja) * 2020-04-30 2021-11-04 国立大学法人京都大学 Rnaウイルス関連疾患の予防又は治療剤
JP2023525981A (ja) * 2020-04-30 2023-06-20 ミノリックス セラピューティクス エセ.エレ. 肺炎症および間質性肺疾患を処置するためのレリグリタゾン

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CA2669763C (en) 2006-11-16 2015-02-17 Bayer Schering Pharma Aktiengesellschaft Ep2 and ep4 agonists as agents for the treatment of influenza a viral infection
CN105555276A (zh) * 2013-03-15 2016-05-04 格穆斯药业股份有限公司 作为治疗病毒性感染的药剂的贝前列素异构体
WO2015109112A1 (en) * 2014-01-16 2015-07-23 Gemmus Pharma Inc. Combination treatment of antibiotic and gpcr agonist for viral/bacterial co-infections
WO2021163400A1 (en) 2020-02-12 2021-08-19 Cytoagents, Inc. Compositions and methods for treating coronavirus infections
CN111184707B (zh) * 2020-02-20 2021-04-27 中山大学 托芬那酸或其药学上可接受的盐在制备预防和/或治疗新型冠状病毒炎症药物中的应用
US20210386725A1 (en) * 2020-06-11 2021-12-16 Chang Gung University Method for inhibiting coronavirus infection and replication
US20240009214A1 (en) 2020-12-02 2024-01-11 Cipla Limited Method of Treating Viral Infection

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WO2008058766A1 (en) * 2006-11-16 2008-05-22 Bayer Schering Pharma Aktiengesellschaft Ep2 and ep4 agonists as agents for the treatment of influenza a viral infection

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020516634A (ja) * 2017-04-12 2020-06-11 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated インフルエンザウイルス感染の処置方法および併用療法
JP2021116296A (ja) * 2020-01-21 2021-08-10 アカデミー オブ ミリタリー メディカル サイエンシズ コロナウイルス感染の治療におけるファビピラビルの使用
JP7716189B2 (ja) 2020-01-21 2025-07-31 アカデミー オブ ミリタリー メディカル サイエンシズ コロナウイルス感染の治療におけるファビピラビルの使用
WO2021221111A1 (ja) * 2020-04-30 2021-11-04 国立大学法人京都大学 Rnaウイルス関連疾患の予防又は治療剤
JPWO2021221111A1 (enExample) * 2020-04-30 2021-11-04
JP2023525981A (ja) * 2020-04-30 2023-06-20 ミノリックス セラピューティクス エセ.エレ. 肺炎症および間質性肺疾患を処置するためのレリグリタゾン
JP7715353B2 (ja) 2020-04-30 2025-07-30 国立大学法人京都大学 Rnaウイルス関連疾患の予防又は治療剤

Also Published As

Publication number Publication date
CN102655859A (zh) 2012-09-05
CA2777384A1 (en) 2011-04-21
EP2488168A1 (en) 2012-08-22
KR20120093955A (ko) 2012-08-23
US20150196578A1 (en) 2015-07-16
AU2010306914A1 (en) 2012-04-19
BR112012008959A2 (pt) 2019-09-24
US20120190637A1 (en) 2012-07-26
NZ599128A (en) 2014-02-28
WO2011047048A1 (en) 2011-04-21

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