JP2013505223A5 - - Google Patents

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Publication number
JP2013505223A5
JP2013505223A5 JP2012529298A JP2012529298A JP2013505223A5 JP 2013505223 A5 JP2013505223 A5 JP 2013505223A5 JP 2012529298 A JP2012529298 A JP 2012529298A JP 2012529298 A JP2012529298 A JP 2012529298A JP 2013505223 A5 JP2013505223 A5 JP 2013505223A5
Authority
JP
Japan
Prior art keywords
bispecific antibody
dose
epcamxcd3 bispecific
period
epcamxcd3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012529298A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013505223A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2010/063795 external-priority patent/WO2011033105A1/en
Publication of JP2013505223A publication Critical patent/JP2013505223A/ja
Publication of JP2013505223A5 publication Critical patent/JP2013505223A5/ja
Pending legal-status Critical Current

Links

JP2012529298A 2009-09-18 2010-09-20 EpCAMxCD3二重特異性抗体を投与するための投与計画 Pending JP2013505223A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US24365109P 2009-09-18 2009-09-18
EP09170715.8 2009-09-18
EP09170715 2009-09-18
US61/243,651 2009-09-18
US34414710P 2010-06-01 2010-06-01
EP10164596.8 2010-06-01
US61/344,147 2010-06-01
EP10164596 2010-06-01
PCT/EP2010/063795 WO2011033105A1 (en) 2009-09-18 2010-09-20 Dosage regimen for administering an epcamxcd3 bispecific antibody

Publications (2)

Publication Number Publication Date
JP2013505223A JP2013505223A (ja) 2013-02-14
JP2013505223A5 true JP2013505223A5 (https=) 2013-11-28

Family

ID=43127167

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012529298A Pending JP2013505223A (ja) 2009-09-18 2010-09-20 EpCAMxCD3二重特異性抗体を投与するための投与計画

Country Status (15)

Country Link
US (1) US20120244161A1 (https=)
EP (1) EP2477653A1 (https=)
JP (1) JP2013505223A (https=)
KR (1) KR20120083359A (https=)
CN (1) CN102711825A (https=)
AU (1) AU2010297258A1 (https=)
BR (1) BR112012008345A2 (https=)
CA (1) CA2774732A1 (https=)
IL (1) IL218637A0 (https=)
IN (1) IN2012DN03172A (https=)
MX (1) MX2012003175A (https=)
NZ (1) NZ598601A (https=)
RU (1) RU2012115480A (https=)
SG (2) SG10201405434VA (https=)
WO (1) WO2011033105A1 (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
KR102293537B1 (ko) * 2016-03-30 2021-08-25 린톤 퍼시픽 아게 요로의 신생물을 치료하는데 사용하기 위한 다중특이적 항체

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WO2012158818A2 (en) * 2011-05-16 2012-11-22 Fabion Pharmaceuticals, Inc. Multi-specific fab fusion proteins and methods of use
UY34504A (es) 2011-12-09 2013-06-28 Amgen Res Munich Gmbh Prevención de los efectos adversos causados por los anticuerpos biespecíficos EpCAMxCD3
GB201302447D0 (en) 2013-02-12 2013-03-27 Oxford Biotherapeutics Ltd Therapeutic and diagnostic target
WO2014127215A1 (en) 2013-02-15 2014-08-21 Biogen Idec Ma Inc. Optimized factor viii gene
EP2961773B1 (en) * 2013-02-26 2019-03-20 Roche Glycart AG Bispecific t cell activating antigen binding molecules
CN106456748A (zh) * 2014-01-08 2017-02-22 小利兰·斯坦福大学托管委员会 小细胞肺癌的靶向疗法
US11008561B2 (en) 2014-06-30 2021-05-18 Bioverativ Therapeutics Inc. Optimized factor IX gene
IL319047A (en) * 2015-08-28 2025-04-01 Amunix Operating Inc Chimeric polypeptide composition and methods for its preparation and use
FI3377103T4 (fi) * 2015-11-19 2025-04-16 Revitope Limited Funktionaalinen vasta-ainefragmenttikomplementointi kaksikomponenttiselle järjestelmälle epätoivottujen solujen uudelleenohjattua tappamista varten
CA3012695A1 (en) 2016-02-01 2017-08-10 Bioverativ Therapeutics Inc. Optimized factor viii genes
US12128102B2 (en) 2016-03-08 2024-10-29 Takeda Pharmaceutical Company Limited Constrained conditionally activated binding proteins
EP3430058A4 (en) 2016-03-15 2019-10-23 Generon (Shanghai) Corporation Ltd. MULTISPECIFIC FAB FUSION PROTEINS AND USES THEREOF
EP3409322A1 (en) * 2017-06-01 2018-12-05 F. Hoffmann-La Roche AG Treatment method
CN111356700A (zh) 2017-09-08 2020-06-30 马弗里克治疗公司 受约束的条件性活化的结合蛋白
EP3847196A4 (en) 2018-09-07 2023-01-04 ITabMed (HK) Limited BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF
WO2020132810A1 (en) 2018-12-24 2020-07-02 Generon (Shanghai) Corporation Ltd. Multispecific antigen binding proteins capable of binding cd19 and cd3, and use thereof
EP4592313A3 (en) 2019-03-05 2025-11-19 Takeda Pharmaceutical Company Limited Constrained conditionally activated binding proteins
KR20220097891A (ko) 2019-09-30 2022-07-08 바이오버라티브 테라퓨틱스 인크. 렌티바이러스 벡터 제형
MX2023000156A (es) 2020-06-24 2023-02-16 Bioverativ Therapeutics Inc Metodos para la eliminacion de factor viii libre de preparaciones de vectores lentivirales modificados para expresar dicha proteina.
MX2024006079A (es) * 2021-11-19 2024-07-29 Wuhan Yzy Biopharma Co Ltd Anticuerpo biespecifico y uso del mismo.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE243754T1 (de) 1987-05-21 2003-07-15 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung
MXPA06004035A (es) 2003-10-16 2006-08-31 Micromet Ag Aglutinantes cd3 de-inmunizados multi-especificos.
PL1874821T3 (pl) * 2005-04-26 2013-09-30 Trion Pharma Gmbh Kombinacja przeciwciał i glikokortykoidów do leczenia raka

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102293537B1 (ko) * 2016-03-30 2021-08-25 린톤 퍼시픽 아게 요로의 신생물을 치료하는데 사용하기 위한 다중특이적 항체
KR102435747B1 (ko) * 2016-03-30 2022-08-23 린톤 퍼시픽 아게 요로의 신생물을 치료하는데 사용하기 위한 다중특이적 항체

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