JP2014523398A5 - - Google Patents
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- Publication number
- JP2014523398A5 JP2014523398A5 JP2014501258A JP2014501258A JP2014523398A5 JP 2014523398 A5 JP2014523398 A5 JP 2014523398A5 JP 2014501258 A JP2014501258 A JP 2014501258A JP 2014501258 A JP2014501258 A JP 2014501258A JP 2014523398 A5 JP2014523398 A5 JP 2014523398A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- integrin
- beta
- antibody
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161466791P | 2011-03-23 | 2011-03-23 | |
| US61/466,791 | 2011-03-23 | ||
| PCT/US2012/030204 WO2012129448A1 (en) | 2011-03-23 | 2012-03-22 | Methods and compositions for improving antiangiogenic therapy with anti-integrins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014523398A JP2014523398A (ja) | 2014-09-11 |
| JP2014523398A5 true JP2014523398A5 (https=) | 2015-05-07 |
Family
ID=46879749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014501258A Pending JP2014523398A (ja) | 2011-03-23 | 2012-03-22 | 抗−インテグリンを用いた抗血管新生療法を改良するための方法及び組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20140079637A1 (https=) |
| EP (1) | EP2688585B1 (https=) |
| JP (1) | JP2014523398A (https=) |
| KR (1) | KR20140030153A (https=) |
| CN (1) | CN103561761A (https=) |
| AU (1) | AU2012230809B2 (https=) |
| CA (1) | CA2830908C (https=) |
| ES (1) | ES2699532T3 (https=) |
| WO (1) | WO2012129448A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012230809B2 (en) * | 2011-03-23 | 2017-06-29 | The Regents Of The University Of California | Methods and compositions for improving antiangiogenic therapy with anti-integrins |
| MX2015008534A (es) | 2012-12-26 | 2017-07-04 | Oncosynergy Inc | COMPOSICIONES DE ANTICUERPO ANTI-INTEGRINA ß1 Y METODOS DE USO DE LAS MISMAS. |
| EP3067698A1 (en) | 2015-03-11 | 2016-09-14 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Pd-ecgf as biomarker of cancer |
| EP3067369A1 (en) | 2015-03-11 | 2016-09-14 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Methods and compositions for the treatment of anti-angiogenic resistant cancer |
| IL298067A (en) | 2015-08-25 | 2023-01-01 | Histide Ag | Compounds for inducing tissue formation and their uses |
| KR20180050744A (ko) * | 2015-09-17 | 2018-05-23 | 히스티드 아게 | 신생물성 세포를 비-신생물성 세포로 전환시키기 위한 약제학적 회합물 및 이것의 용도 |
| US20190330290A1 (en) * | 2015-09-17 | 2019-10-31 | Histide Ag | Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof |
| WO2017046229A1 (en) * | 2015-09-17 | 2017-03-23 | Histide Ag | Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof |
| WO2020145669A1 (ko) * | 2019-01-10 | 2020-07-16 | 에스지메디칼 주식회사 | 항 베타 1 인테그린 인간화 항체 및 이를 포함하는 암치료용 약학 조성물 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5272263A (en) * | 1989-04-28 | 1993-12-21 | Biogen, Inc. | DNA sequences encoding vascular cell adhesion molecules (VCAMS) |
| US6033665A (en) | 1989-09-27 | 2000-03-07 | Elan Pharmaceuticals, Inc. | Compositions and methods for modulating leukocyte adhesion to brain endothelial cells |
| US6165467A (en) | 1991-07-20 | 2000-12-26 | Yoshihide Hagiwara | Stabilized human monoclonal antibody preparation |
| US5840300A (en) | 1995-09-11 | 1998-11-24 | Trustees Of The University Of Pennsylvania | Methods and compositions comprising single chain recombinant antibodies |
| US5846536A (en) * | 1996-10-04 | 1998-12-08 | The Regents Of The University Of California | Restoration of normal phenotype in cancer cells |
| US6596276B1 (en) | 1997-09-30 | 2003-07-22 | Beth Israel Deaconess Medical Center | Method for inhibiting tumor angiogenesis in a living subject |
| CA2328414C (en) * | 1998-05-08 | 2014-04-15 | The Regents Of The University Of California | Methods for detecting and inhibiting angiogenesis |
| WO2000042012A1 (en) | 1999-01-13 | 2000-07-20 | Bayer Corporation | φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS |
| US7928239B2 (en) | 1999-01-13 | 2011-04-19 | Bayer Healthcare Llc | Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas |
| ATE538794T1 (de) | 1999-01-13 | 2012-01-15 | Bayer Healthcare Llc | Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer |
| US6949245B1 (en) | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
| US6716410B1 (en) | 1999-10-26 | 2004-04-06 | The Regents Of The University Of California | Reagents and methods for diagnosing, imaging and treating atherosclerotic disease |
| JP3789066B2 (ja) | 1999-12-08 | 2006-06-21 | 三菱電機株式会社 | 液晶表示装置 |
| US8725620B2 (en) | 2000-07-10 | 2014-05-13 | Nobuyoshi Morimoto | System and method for negotiating improved terms for products and services being purchased through the internet |
| US6878714B2 (en) | 2001-01-12 | 2005-04-12 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| WO2002097038A2 (en) * | 2001-05-25 | 2002-12-05 | Human Genome Sciences, Inc. | Chemokine beta-1 fusion proteins |
| EP1414491A4 (en) | 2001-07-09 | 2005-07-06 | Elan Pharm Inc | METHOD OF INHIBITING THE TOXICITY OF AMYLOID |
| CA2466762A1 (en) | 2001-12-04 | 2003-06-12 | Onyx Pharmaceuticals, Inc. | Raf-mek-erk pathway inhibitors to treat cancer |
| EA010485B1 (ru) | 2003-07-23 | 2008-10-30 | Байер Фамэсьютиклс Копэрейшн | Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты) |
| JP4932495B2 (ja) | 2004-01-23 | 2012-05-16 | アムゲン インコーポレイテッド | 化合物及び使用方法 |
| US7618627B2 (en) * | 2004-06-03 | 2009-11-17 | The Regents Of The University Of California | Method of increasing radiation sensitivity by inhibition of beta one integrin |
| EP1893647A2 (en) | 2005-06-23 | 2008-03-05 | MedImmune, Inc. | Antibody formulations having optimized aggregation and fragmentation profiles |
| AR059066A1 (es) | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
| JP4997432B2 (ja) * | 2006-02-10 | 2012-08-08 | 学校法人慶應義塾 | 神経幹細胞の増殖抑制剤 |
| HRP20150884T1 (hr) * | 2006-03-21 | 2015-09-25 | Genentech, Inc. | Kombinacijska terapija koja ukljuäśuje antagoniste alfa5beta1 |
| ZA200807754B (en) * | 2006-03-21 | 2009-12-30 | Genentech Inc | Combinatorial therapy involving alpha5beta1 antagonists |
| EP2066689A4 (en) * | 2006-09-07 | 2010-04-28 | Univ South Florida | HYD1-PEPTIDE AS ANTICREMENT |
| WO2009009114A2 (en) * | 2007-07-12 | 2009-01-15 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for treating and diagnosing cancer |
| AU2008282331A1 (en) * | 2007-07-27 | 2009-02-05 | Facet Biotech Corporation | Pharmaceutical combinations comprising a tyrosine kinase inhibitor and an antibody against integrin alpha 1 beta 5 (CD49E) |
| EP2060287B1 (de) * | 2007-11-14 | 2011-06-15 | BrainLAB AG | Medikamentenzuführungssystem für CED (Convection Enhanced Delivery)-Katheterinfusionen |
| WO2010022139A1 (en) * | 2008-08-20 | 2010-02-25 | New York Blood Center, Inc. | Regulation of integrin surface expression |
| JP2012513195A (ja) * | 2008-12-23 | 2012-06-14 | アストラゼネカ アクチボラグ | α５β１に向けられた標的化結合剤およびその使用 |
| MY173526A (en) * | 2009-03-25 | 2020-01-31 | Genentech Inc | Novel anti-?5?1 antibodies and uses thereof |
| AU2012230809B2 (en) * | 2011-03-23 | 2017-06-29 | The Regents Of The University Of California | Methods and compositions for improving antiangiogenic therapy with anti-integrins |
| MX2015008534A (es) * | 2012-12-26 | 2017-07-04 | Oncosynergy Inc | COMPOSICIONES DE ANTICUERPO ANTI-INTEGRINA ß1 Y METODOS DE USO DE LAS MISMAS. |
-
2012
- 2012-03-22 AU AU2012230809A patent/AU2012230809B2/en active Active
- 2012-03-22 CA CA2830908A patent/CA2830908C/en active Active
- 2012-03-22 KR KR1020137027236A patent/KR20140030153A/ko not_active Ceased
- 2012-03-22 CN CN201280024596.8A patent/CN103561761A/zh active Pending
- 2012-03-22 EP EP12760157.3A patent/EP2688585B1/en active Active
- 2012-03-22 JP JP2014501258A patent/JP2014523398A/ja active Pending
- 2012-03-22 WO PCT/US2012/030204 patent/WO2012129448A1/en not_active Ceased
- 2012-03-22 ES ES12760157T patent/ES2699532T3/es active Active
- 2012-03-22 US US14/006,669 patent/US20140079637A1/en not_active Abandoned
-
2018
- 2018-01-12 US US15/869,970 patent/US11185585B2/en active Active
-
2021
- 2021-10-27 US US17/512,500 patent/US20220111045A1/en not_active Abandoned
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