JP2013505008A - 患者が免疫療法に対するレスポンダーかそうでなきかを同定するための方法 - Google Patents

患者が免疫療法に対するレスポンダーかそうでなきかを同定するための方法 Download PDF

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JP2013505008A
JP2013505008A JP2012529295A JP2012529295A JP2013505008A JP 2013505008 A JP2013505008 A JP 2013505008A JP 2012529295 A JP2012529295 A JP 2012529295A JP 2012529295 A JP2012529295 A JP 2012529295A JP 2013505008 A JP2013505008 A JP 2013505008A
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gene
responder
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ブリシャール，ヴァンサン
ディジエ，バンジャマン，ジョルジュ，エリー，レア，ジスラン
グルセル，オリヴィエ
ルアヘド，ジャミラ
ウロア−モントヤ，フェルナンド
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グラクソスミスクライン バイオロジカルズ ソシエテ アノニム
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development

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  • Urology & Nephrology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2012529295A 2009-09-18 2010-09-17 患者が免疫療法に対するレスポンダーかそうでなきかを同定するための方法 Ceased JP2013505008A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US27704609P 2009-09-18 2009-09-18
US61/277,046 2009-09-18
US27838709P 2009-10-06 2009-10-06
US61/278,387 2009-10-06
GB0917457.4 2009-10-06
GBGB0917457.4A GB0917457D0 (en) 2009-10-06 2009-10-06 Method
PCT/EP2010/063751 WO2011033095A1 (en) 2009-09-18 2010-09-17 Method for identifying whether a patient will be responder or not to immunotherapy

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JP2013505008A true JP2013505008A (ja) 2013-02-14
JP2013505008A5 JP2013505008A5 (https=) 2013-11-07

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JP2012529295A Ceased JP2013505008A (ja) 2009-09-18 2010-09-17 患者が免疫療法に対するレスポンダーかそうでなきかを同定するための方法

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US (1) US20110070268A1 (https=)
EP (1) EP2478116A1 (https=)
JP (1) JP2013505008A (https=)
KR (1) KR20130055553A (https=)
CN (1) CN102597269A (https=)
AU (1) AU2010297248A1 (https=)
BR (1) BR112012006088A2 (https=)
CA (1) CA2773666A1 (https=)
EA (1) EA201290107A1 (https=)
GB (1) GB0917457D0 (https=)
IL (1) IL218313A0 (https=)
MX (1) MX2012003329A (https=)
SG (1) SG179129A1 (https=)
WO (1) WO2011033095A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018503373A (ja) * 2014-12-30 2018-02-08 ジェネンテック， インコーポレイテッド がんの予後診断及び治療のための方法及び組成物
JP2024160217A (ja) * 2020-03-17 2024-11-13 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 治療に対するレスポンダを決定するための方法およびシステム

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WO2014151026A1 (en) * 2013-03-15 2014-09-25 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
WO2016003810A1 (en) 2014-07-02 2016-01-07 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
CN109416925A (zh) * 2016-05-05 2019-03-01 南托米克斯有限责任公司 检查点失效和使检查点失效的方法
KR102169901B1 (ko) * 2019-05-17 2020-10-26 연세대학교 산학협력단 Dna 메틸화를 이용한 면역 항암 요법의 치료 반응에 관한 정보 제공 방법 및 이를 이용한 키트
EP4161658A4 (en) * 2020-06-01 2024-10-02 Dana-Farber Cancer Institute, Inc. Methods for modulating mhc-i expression and immunotherapy uses thereof
CN115495026B (zh) * 2022-11-21 2023-03-10 杭州字节方舟科技有限公司 一种优化内存处理方法、装置、设备及存储介质

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Cited By (4)

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Publication number Priority date Publication date Assignee Title
JP2018503373A (ja) * 2014-12-30 2018-02-08 ジェネンテック， インコーポレイテッド がんの予後診断及び治療のための方法及び組成物
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US12385098B2 (en) 2014-12-30 2025-08-12 Genentech, Inc. Methods and compositions for prognosis and treatment of cancers
JP2024160217A (ja) * 2020-03-17 2024-11-13 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 治療に対するレスポンダを決定するための方法およびシステム

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IL218313A0 (en) 2012-04-30
BR112012006088A2 (pt) 2020-08-11
AU2010297248A1 (en) 2012-04-12
EP2478116A1 (en) 2012-07-25
CA2773666A1 (en) 2011-03-24
CN102597269A (zh) 2012-07-18
EA201290107A1 (ru) 2012-10-30
KR20130055553A (ko) 2013-05-28
WO2011033095A1 (en) 2011-03-24
GB0917457D0 (en) 2009-11-18
MX2012003329A (es) 2012-04-20
SG179129A1 (en) 2012-05-30
US20110070268A1 (en) 2011-03-24

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