JP2013502918A - 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド - Google Patents
髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド Download PDFInfo
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- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 description 1
- 229960001661 ursodiol Drugs 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000010698 whale oil Substances 0.000 description 1
- 241000228158 x Triticosecale Species 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US23757609P | 2009-08-27 | 2009-08-27 | |
| US61/237,576 | 2009-08-27 | ||
| PCT/IB2010/002260 WO2011024072A2 (en) | 2009-08-27 | 2010-08-27 | Hybrid polypeptides including meningococcal fhbp sequences |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2015036548A Division JP2015110653A (ja) | 2009-08-27 | 2015-02-26 | 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド |
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| JP2013502918A true JP2013502918A (ja) | 2013-01-31 |
| JP2013502918A5 JP2013502918A5 (https=) | 2013-09-19 |
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| JP2015036548A Pending JP2015110653A (ja) | 2009-08-27 | 2015-02-26 | 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド |
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| US (1) | US20110076300A1 (https=) |
| EP (2) | EP3017828A1 (https=) |
| JP (2) | JP2013502918A (https=) |
| CN (2) | CN102596240B (https=) |
| AU (1) | AU2010288240B2 (https=) |
| BR (1) | BR112012004275A2 (https=) |
| CA (1) | CA2772104A1 (https=) |
| ES (1) | ES2562259T3 (https=) |
| NZ (2) | NZ598458A (https=) |
| WO (1) | WO2011024072A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0819633D0 (en) * | 2008-10-25 | 2008-12-03 | Isis Innovation | Composition |
| WO2011027222A2 (en) | 2009-09-02 | 2011-03-10 | Novartis Ag | Immunogenic compositions including tlr activity modulators |
| BR112012014624A8 (pt) | 2009-12-15 | 2017-12-26 | Novartis Ag | suspensão homogênea de compostos de imunopotenciação e usos dos destes |
| CN107913396B (zh) | 2010-08-23 | 2022-03-08 | 惠氏有限责任公司 | 脑膜炎萘瑟氏菌rLP2086抗原的稳定制剂 |
| AU2011295853A1 (en) | 2010-09-01 | 2013-04-04 | Irm Llc | Adsorption of immunopotentiators to insoluble metal salts |
| AU2011300409B2 (en) | 2010-09-10 | 2015-03-26 | Wyeth Llc | Non-lipidated variants of Neisseria meningitidis ORF2086 antigens |
| WO2012117377A1 (en) | 2011-03-02 | 2012-09-07 | Novartis Ag | Combination vaccines with lower doses of antigen and/or adjuvant |
| SI2822947T1 (sl) | 2012-03-07 | 2016-10-28 | Glaxosmithkline Biologicals S.A. | Argininske soli TLR7 agonista |
| MX372965B (es) | 2012-03-08 | 2020-04-01 | Glaxosmithkline Biologicals Sa | Formulaciones adyuvadas de vacunas de difteria, tetanos y tos ferina (dtp) de refuerzo. |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| MY198910A (en) * | 2012-03-09 | 2023-10-02 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| WO2014016152A1 (en) | 2012-07-27 | 2014-01-30 | Institut National De La Sante Et De La Recherche Medicale | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| JP6324961B2 (ja) | 2012-09-06 | 2018-05-16 | ノバルティス アーゲー | 血清群ｂ髄膜炎菌とｄ／ｔ／ｐとの組み合わせワクチン |
| WO2014136064A2 (en) | 2013-03-08 | 2014-09-12 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| WO2016132294A1 (en) | 2015-02-19 | 2016-08-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| AU2016262823A1 (en) * | 2015-05-18 | 2017-12-07 | Universita' Degli Studi Di Trento | Immunogenic compositions containing bacterial outer membrane vesicles and therapeutic uses thereof |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| BR112019003992A2 (pt) | 2016-09-02 | 2019-05-28 | Sanofi Pasteur Inc | vacina contra neisseria meningitidis |
| AU2018215585B2 (en) | 2017-01-31 | 2022-03-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| CN107151270B (zh) * | 2017-03-22 | 2018-07-31 | 武汉博沃生物科技有限公司 | 重组ΔfHbp-NadA融合蛋白载体及其制备方法和应用 |
| GB201809622D0 (en) * | 2018-06-12 | 2018-07-25 | Evox Therapeutics Ltd | Engineering extracellular vesicles for affinity purification |
| WO2021059181A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| IN202321021121A (https=) * | 2023-03-24 | 2024-04-19 |
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2010
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- 2010-08-27 CA CA2772104A patent/CA2772104A1/en not_active Abandoned
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- 2010-08-27 NZ NZ598458A patent/NZ598458A/en not_active IP Right Cessation
- 2010-08-27 EP EP15193267.0A patent/EP3017828A1/en not_active Withdrawn
- 2010-08-27 EP EP10765842.9A patent/EP2470204B1/en not_active Not-in-force
- 2010-08-27 JP JP2012526142A patent/JP2013502918A/ja not_active Ceased
- 2010-08-27 ES ES10765842.9T patent/ES2562259T3/es active Active
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- 2010-08-27 US US12/870,718 patent/US20110076300A1/en not_active Abandoned
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| JP2006512402A (ja) * | 2002-10-11 | 2006-04-13 | カイロン ソチエタ ア レスポンサビリタ リミタータ | 高毒性髄膜炎菌系統に対する広範な防御のためのポリペプチド−ワクチン |
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Also Published As
| Publication number | Publication date |
|---|---|
| BR112012004275A2 (pt) | 2016-11-16 |
| CN102596240A (zh) | 2012-07-18 |
| ES2562259T3 (es) | 2016-03-03 |
| NZ598458A (en) | 2014-03-28 |
| EP3017828A1 (en) | 2016-05-11 |
| AU2010288240B2 (en) | 2014-03-27 |
| WO2011024072A3 (en) | 2011-06-09 |
| AU2010288240A1 (en) | 2012-03-22 |
| US20110076300A1 (en) | 2011-03-31 |
| CN102596240B (zh) | 2015-02-04 |
| EP2470204A2 (en) | 2012-07-04 |
| CN104650241A (zh) | 2015-05-27 |
| NZ622048A (en) | 2015-10-30 |
| EP2470204B1 (en) | 2015-12-16 |
| CA2772104A1 (en) | 2011-03-03 |
| WO2011024072A2 (en) | 2011-03-03 |
| JP2015110653A (ja) | 2015-06-18 |
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