JP2013502204A5 - - Google Patents
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- Publication number
- JP2013502204A5 JP2013502204A5 JP2012525000A JP2012525000A JP2013502204A5 JP 2013502204 A5 JP2013502204 A5 JP 2013502204A5 JP 2012525000 A JP2012525000 A JP 2012525000A JP 2012525000 A JP2012525000 A JP 2012525000A JP 2013502204 A5 JP2013502204 A5 JP 2013502204A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- cdr3
- cdr1
- cdr2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000427 antigen Substances 0.000 claims 11
- 102000036639 antigens Human genes 0.000 claims 11
- 108091007433 antigens Proteins 0.000 claims 11
- 102000005962 receptors Human genes 0.000 claims 10
- 108020003175 receptors Proteins 0.000 claims 10
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 7
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2009903928 | 2009-08-20 | ||
| AU2009903928A AU2009903928A0 (en) | 2009-08-20 | Anti P2X7 receptor antibodies and fragments thereof | |
| PCT/AU2010/001070 WO2011020155A1 (en) | 2009-08-20 | 2010-08-20 | Anti p2x7 receptor antibodies and fragments thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016019816A Division JP6224141B2 (ja) | 2009-08-20 | 2016-02-04 | 抗ｐ２ｘ７受容体抗体およびその断片 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013502204A JP2013502204A (ja) | 2013-01-24 |
| JP2013502204A5 true JP2013502204A5 (https=) | 2013-10-03 |
| JP5936067B2 JP5936067B2 (ja) | 2016-06-15 |
Family
ID=43606479
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012525000A Active JP5936067B2 (ja) | 2009-08-20 | 2010-08-20 | 抗ｐ２ｘ７受容体抗体およびその断片 |
| JP2016019816A Active JP6224141B2 (ja) | 2009-08-20 | 2016-02-04 | 抗ｐ２ｘ７受容体抗体およびその断片 |
| JP2017193317A Active JP6417016B2 (ja) | 2009-08-20 | 2017-10-03 | 抗ｐ２ｘ７受容体抗体およびその断片 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016019816A Active JP6224141B2 (ja) | 2009-08-20 | 2016-02-04 | 抗ｐ２ｘ７受容体抗体およびその断片 |
| JP2017193317A Active JP6417016B2 (ja) | 2009-08-20 | 2017-10-03 | 抗ｐ２ｘ７受容体抗体およびその断片 |
Country Status (5)
| Country | Link |
|---|---|
| US (6) | US9127059B2 (https=) |
| EP (3) | EP2467404B1 (https=) |
| JP (3) | JP5936067B2 (https=) |
| ES (3) | ES2704711T3 (https=) |
| WO (1) | WO2011020155A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4384852B2 (ja) | 2001-01-17 | 2009-12-16 | イントリート ピーティーワイ リミテッド | 非機能性ｐ２ｘ７レセプター抗体、癌及びその他の容態の診断及び処置 |
| ES2619681T3 (es) | 2007-09-14 | 2017-06-26 | Biosceptre (Aust) Pty Ltd | Novedosos epítopos P2X7 |
| ATE542139T1 (de) | 2007-09-14 | 2012-02-15 | Biosceptre Int Ltd | Purinerge (p2x)-rezeptoren in extrazellulärer körperflüssigkeit |
| CN102143978B (zh) | 2008-07-04 | 2015-02-18 | 生物权威国际有限公司 | 抗p2x7肽和表位 |
| EP2467404B1 (en) | 2009-08-20 | 2015-09-30 | Biosceptre International Limited | Anti p2x7 receptor antibodies and fragments thereof |
| WO2011075789A1 (en) | 2009-12-24 | 2011-06-30 | Biosceptre International Limited | Antibodies to non-functional oligomeric p2x7 receptors |
| EP2613808B1 (en) | 2010-09-10 | 2017-11-08 | Biosceptre (Aust) Pty Ltd | Companion animal cancer treatments with an anti p2x7 antibody |
| MX349321B (es) | 2011-07-01 | 2017-07-21 | Biosceptre (Aust) Pty Ltd | Terapia combinada. |
| US20180037650A1 (en) * | 2015-04-02 | 2018-02-08 | Biosceptre (Uk) Limited | Pain Treatment |
| US12121539B2 (en) * | 2015-09-11 | 2024-10-22 | Biosceptre (Aust) Pty Ltd | Chimeric antigen receptors and uses thereof |
| GB201522541D0 (en) * | 2015-12-21 | 2016-02-03 | Inst Research In Biomedicine | Compositions |
| MX2019004410A (es) * | 2016-10-21 | 2019-09-26 | Biosceptre Uk Ltd | Particulas citotoxicas. |
| CN112166193A (zh) | 2018-05-21 | 2021-01-01 | 生物权威（英国）有限公司 | 具有经修饰的接头结构域的嵌合抗原受体及其用途 |
| FR3084365B1 (fr) * | 2018-07-27 | 2020-10-23 | Cisbio Bioassays | Anticorps a domaine unique qui se lient a la proteine g alpha |
| US12410225B2 (en) | 2018-11-08 | 2025-09-09 | Orionis Biosciences, Inc | Modulation of dendritic cell lineages |
| CN110054691B (zh) * | 2019-05-09 | 2021-09-07 | 潍坊医学院 | 一种抗人p2rx7单克隆抗体的杂交瘤细胞系 |
| CN114173811A (zh) * | 2019-07-26 | 2022-03-11 | 生物权威(澳大利亚)有限责任公司 | P2x7受体靶向治疗 |
| CN111171149B (zh) * | 2020-02-23 | 2021-09-07 | 北京康普美特创新医药科技有限责任公司 | 一种抗补体c5分子的人源化单链抗体及其应用 |
| CN111234016B (zh) * | 2020-02-23 | 2021-09-07 | 北京康普美特创新医药科技有限责任公司 | 一种抗补体c5分子的全人源单克隆抗体及应用 |
| EP4304610A4 (en) * | 2021-03-11 | 2025-03-05 | Biosceptre (Aust) Pty Ltd | Novel cell therapy system |
| US20240368282A1 (en) * | 2021-09-01 | 2024-11-07 | Biosceptre (Aust) Pty Ltd | Methods and compositions for stimulating immune activity |
| WO2025042968A1 (en) * | 2023-08-22 | 2025-02-27 | Integral Molecular, Inc. | Compositions and methods related to chicken recombinant heavy-chain only antibodies |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3443119B2 (ja) * | 1989-08-07 | 2003-09-02 | ペプテック リミテッド | 腫瘍壊死因子結合リガンド |
| IE920765A1 (en) | 1991-03-12 | 1992-09-23 | Scripps Research Inst | Cell surface receptors homologous to coagulation factors v¹and viii |
| AU2566595A (en) | 1994-05-27 | 1995-12-21 | Glaxo Group Limited | P-2x receptors (purinoceptor family) |
| WO1997006256A2 (en) | 1995-08-09 | 1997-02-20 | Institut National De La Sante Et De La Recherche Medicale | Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis |
| JP2001521372A (ja) | 1996-04-30 | 2001-11-06 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ヒトＰ２ｘ４レセプタースプライス−変異体 |
| US6303338B1 (en) | 1996-08-16 | 2001-10-16 | Human Genome Sciences, Inc. | Pancreas-derived plasminogen activator inhibitor |
| US6306393B1 (en) | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| JP3885177B2 (ja) | 1997-03-26 | 2007-02-21 | 大塚製薬株式会社 | ヒト遺伝子 |
| US6133434A (en) | 1997-04-28 | 2000-10-17 | Glaxo Group Limited | Purinergic receptor |
| EP1086223B1 (en) | 1998-06-01 | 2009-07-29 | Agensys, Inc. | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof |
| DE19829473C2 (de) | 1998-07-01 | 2000-08-10 | Magnus Von Knebel Doeberitz Ch | Verfahren zur frühen Diagnose von Carcinomen |
| EP1157038A4 (en) | 1999-02-26 | 2005-01-19 | Smithkline Beecham Corp | CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17) |
| AUPP991199A0 (en) | 1999-04-21 | 1999-05-13 | University Of Sydney, The | Methods for diagnosing pre-cancerous and cancerous conditions |
| AU1339701A (en) | 1999-10-22 | 2001-05-08 | Lifespan Biosciences, Inc. | Anti-cancer nucleic acid and protein targets |
| AUPR201500A0 (en) | 2000-12-11 | 2001-01-11 | Biosceptre Pty Ltd | Methods for identifying pre-neoplastic and neoplastic states in mammals |
| JP4384852B2 (ja) | 2001-01-17 | 2009-12-16 | イントリート ピーティーワイ リミテッド | 非機能性ｐ２ｘ７レセプター抗体、癌及びその他の容態の診断及び処置 |
| CA2450793A1 (en) * | 2001-06-20 | 2002-12-27 | Prochon Biotech Ltd. | Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof |
| CN100497386C (zh) | 2001-09-03 | 2009-06-10 | 因特里特有限公司 | 非功能性p2x7受体的抗体及其应用 |
| EP1469072B1 (en) | 2003-04-17 | 2007-08-29 | Affectis Pharmaceuticals AG | Means and methods for diagnosing and treating affective disorders |
| CA2572289A1 (en) * | 2004-06-30 | 2006-08-17 | Centocor, Inc. | Anti-mcp-1 antibodies, compositions, methods and uses |
| CA2575791A1 (en) * | 2004-08-03 | 2006-02-16 | Dyax Corp. | Hk1-binding proteins |
| CA2607541A1 (en) | 2005-05-05 | 2006-12-28 | Medicure International Inc. | Inhibition of atp-mediated, p2x7 dependent pathways by pyridoxal-5-phosphaste and vitamin b6 related compounds |
| US7767789B2 (en) | 2005-06-02 | 2010-08-03 | University Hopitals of Cleveland | Truncated proteins as cancer markers |
| EP1904630A4 (en) | 2005-06-16 | 2009-10-21 | Bionomics Ltd | METHODS OF TREATING AND DIAGNOSING EPILEPSY BY DETECTING MUTATIONS OF THE SCN1A GENE |
| EP1929305A2 (en) | 2005-08-31 | 2008-06-11 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in leukemia signaling pathways |
| JP5364378B2 (ja) * | 2005-11-09 | 2013-12-11 | アボット・ラボラトリーズ | ヒトｂｎｐ免疫特異的抗体 |
| JP2010505426A (ja) | 2006-10-10 | 2010-02-25 | バイオスセプター インターナショナル リミテッド | 非機能性ｐ２ｘ７受容体に対する抗体を産生するハイブリドーマ |
| WO2008043146A1 (en) | 2006-10-10 | 2008-04-17 | Biosceptre International Limited | Antibodies against non functional p2x7 receptor |
| ATE542139T1 (de) | 2007-09-14 | 2012-02-15 | Biosceptre Int Ltd | Purinerge (p2x)-rezeptoren in extrazellulärer körperflüssigkeit |
| ES2619681T3 (es) * | 2007-09-14 | 2017-06-26 | Biosceptre (Aust) Pty Ltd | Novedosos epítopos P2X7 |
| CN102143978B (zh) | 2008-07-04 | 2015-02-18 | 生物权威国际有限公司 | 抗p2x7肽和表位 |
| EP2467404B1 (en) | 2009-08-20 | 2015-09-30 | Biosceptre International Limited | Anti p2x7 receptor antibodies and fragments thereof |
| WO2011075789A1 (en) | 2009-12-24 | 2011-06-30 | Biosceptre International Limited | Antibodies to non-functional oligomeric p2x7 receptors |
| US8828944B2 (en) | 2010-04-22 | 2014-09-09 | Institut Gustave Roussy | Compounds and uses thereof to induce an immunogenic cancer cell death in a subject |
| EP2613808B1 (en) | 2010-09-10 | 2017-11-08 | Biosceptre (Aust) Pty Ltd | Companion animal cancer treatments with an anti p2x7 antibody |
| MX349321B (es) | 2011-07-01 | 2017-07-21 | Biosceptre (Aust) Pty Ltd | Terapia combinada. |
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2010
- 2010-08-20 EP EP10809371.7A patent/EP2467404B1/en active Active
- 2010-08-20 JP JP2012525000A patent/JP5936067B2/ja active Active
- 2010-08-20 WO PCT/AU2010/001070 patent/WO2011020155A1/en not_active Ceased
- 2010-08-20 ES ES15178381T patent/ES2704711T3/es active Active
- 2010-08-20 ES ES18175591T patent/ES2904911T3/es active Active
- 2010-08-20 EP EP15178381.8A patent/EP2966090B1/en active Active
- 2010-08-20 EP EP18175591.9A patent/EP3395832B1/en active Active
- 2010-08-20 ES ES10809371.7T patent/ES2557456T3/es active Active
- 2010-08-20 US US13/391,619 patent/US9127059B2/en active Active
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2015
- 2015-03-27 US US14/671,254 patent/US9688771B2/en active Active
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2016
- 2016-02-04 JP JP2016019816A patent/JP6224141B2/ja active Active
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2017
- 2017-05-18 US US15/599,396 patent/US10053508B2/en active Active
- 2017-10-03 JP JP2017193317A patent/JP6417016B2/ja active Active
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2018
- 2018-07-11 US US16/032,973 patent/US10988532B2/en active Active
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2021
- 2021-03-10 US US17/198,179 patent/US12129295B2/en active Active
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2024
- 2024-09-24 US US18/895,282 patent/US20250084161A1/en active Pending