MX349321B - Terapia combinada. - Google Patents
Terapia combinada.Info
- Publication number
- MX349321B MX349321B MX2014000199A MX2014000199A MX349321B MX 349321 B MX349321 B MX 349321B MX 2014000199 A MX2014000199 A MX 2014000199A MX 2014000199 A MX2014000199 A MX 2014000199A MX 349321 B MX349321 B MX 349321B
- Authority
- MX
- Mexico
- Prior art keywords
- combination therapy
- individuals
- cancer
- minimising
- progression
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 102100037602 P2X purinoceptor 7 Human genes 0.000 abstract 1
- 101710189965 P2X purinoceptor 7 Proteins 0.000 abstract 1
- 230000008348 humoral response Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
Abstract
La presente invención se refiere a un receptor P2X7 o un fragmento del mismo para usarse en un método para minimizar la progresión del cáncer en un individuo, en donde el individuo ha recibido un sitio no propio de unión de antígenos para el tratamiento del cáncer, en donde el fragmento de un receptor P2X7 es capaz de formar una respuesta inmunitaria a un receptor P2X7, y que incluye una secuencia de aminoácidos seleccionada del grupo que consiste en SEQ ID NO: 2, 3 y 4.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2011902623A AU2011902623A0 (en) | 2011-07-01 | Combination therapy | |
PCT/AU2012/000795 WO2013003895A1 (en) | 2011-07-01 | 2012-07-02 | Combination therapy |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014000199A MX2014000199A (es) | 2014-06-11 |
MX349321B true MX349321B (es) | 2017-07-21 |
Family
ID=47436374
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014000199A MX349321B (es) | 2011-07-01 | 2012-07-02 | Terapia combinada. |
Country Status (11)
Country | Link |
---|---|
US (3) | US9566318B2 (es) |
EP (1) | EP2726095B1 (es) |
JP (2) | JP6305920B2 (es) |
CN (1) | CN103702683B (es) |
AU (1) | AU2012278921B2 (es) |
BR (1) | BR112013033974A2 (es) |
CA (1) | CA2840251C (es) |
ES (1) | ES2689272T3 (es) |
MX (1) | MX349321B (es) |
WO (1) | WO2013003895A1 (es) |
ZA (1) | ZA201400120B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60230482D1 (de) | 2001-01-17 | 2009-02-05 | Intreat Pty Ltd | Antikörper gegen nichtfunktionelle p 2 x 7 rezeptoren, diagnose und behandlung von krebs und anderen leiden |
NZ583894A (en) | 2007-09-14 | 2013-01-25 | Biosceptre Int Ltd | Antibodies that bind to a non atp binding p2x7 receptor |
CA2729868C (en) | 2008-07-04 | 2018-07-10 | Biosceptre International Limited | Anti- p2x7 peptides and epitopes |
EP2966090B1 (en) | 2009-08-20 | 2018-10-10 | Biosceptre (Aust) Pty Ltd | Anti p2x7 receptor antibodies and fragments thereof |
ES2667003T3 (es) | 2009-12-24 | 2018-05-09 | Biosceptre (Aust) Pty Ltd | Anticuerpos para receptores P2X7 oligoméricos no funcionales |
EP2613808B1 (en) | 2010-09-10 | 2017-11-08 | Biosceptre (Aust) Pty Ltd | Companion animal cancer treatments with an anti p2x7 antibody |
US8846107B2 (en) | 2010-12-29 | 2014-09-30 | Ecolab Usa Inc. | In situ generation of peroxycarboxylic acids at alkaline pH, and methods of use thereof |
US8889900B2 (en) | 2010-12-29 | 2014-11-18 | Ecolab Usa Inc. | Sugar ester peracid on site generator and formulator |
CA2840251C (en) | 2011-07-01 | 2023-09-12 | Biosceptre International Limited | Combination therapy of diseases that are associated with non-functional p2x7 receptor expression |
US9321664B2 (en) | 2011-12-20 | 2016-04-26 | Ecolab Usa Inc. | Stable percarboxylic acid compositions and uses thereof |
US11040902B2 (en) | 2014-12-18 | 2021-06-22 | Ecolab Usa Inc. | Use of percarboxylic acids for scale prevention in treatment systems |
JP6802166B2 (ja) | 2014-12-18 | 2020-12-16 | エコラボ ユーエスエー インコーポレイティド | 多価アルコールホルマートによるペルオキシギ酸の生成 |
CA2971416C (en) | 2014-12-18 | 2024-01-23 | Ecolab Usa Inc. | Methods for forming peroxyformic acid and uses thereof |
CN109862883A (zh) * | 2016-10-21 | 2019-06-07 | 生物权威(英国)有限公司 | 细胞毒性颗粒 |
MA55805A (fr) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | Métodes de modulation de l'activité immunitaire |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE920765A1 (en) | 1991-03-12 | 1992-09-23 | Scripps Research Inst | Cell surface receptors homologous to coagulation factors v¹and viii |
US5500161A (en) | 1993-09-21 | 1996-03-19 | Massachusetts Institute Of Technology And Virus Research Institute | Method for making hydrophobic polymeric microparticles |
JPH10501122A (ja) | 1994-05-27 | 1998-02-03 | グラクソ、グループ、リミテッド | P▲下2x▼レセプター(プリノセプターファミリー) |
CA2228999A1 (en) | 1995-08-09 | 1997-02-20 | Institut National De La Sante Et De La Recherche Medicale | Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis |
WO1997041222A1 (en) | 1996-04-30 | 1997-11-06 | Smithkline Beecham P.L.C. | HUMAN P2x4 RECEPTOR SPLICE-VARIANTS |
US6303338B1 (en) | 1996-08-16 | 2001-10-16 | Human Genome Sciences, Inc. | Pancreas-derived plasminogen activator inhibitor |
US6306393B1 (en) | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
JP3885177B2 (ja) | 1997-03-26 | 2007-02-21 | 大塚製薬株式会社 | ヒト遺伝子 |
US6133434A (en) | 1997-04-28 | 2000-10-17 | Glaxo Group Limited | Purinergic receptor |
ES2329851T3 (es) | 1998-06-01 | 2009-12-01 | Agensys, Inc. | Nuevos antigenos transmembranables expresados en canceres humano y utilizacion de los mismos. |
DE19829473C2 (de) | 1998-07-01 | 2000-08-10 | Magnus Von Knebel Doeberitz Ch | Verfahren zur frühen Diagnose von Carcinomen |
EP1157038A4 (en) | 1999-02-26 | 2005-01-19 | Smithkline Beecham Corp | CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17) |
AUPP991199A0 (en) | 1999-04-21 | 1999-05-13 | University Of Sydney, The | Methods for diagnosing pre-cancerous and cancerous conditions |
NL1012452C2 (nl) | 1999-06-28 | 2001-01-02 | Univ Delft Tech | Werkwijze voor de bereiding van eiwit-agglomeraten, eiwit-agglomeraten, een levensmiddel en een farmaceutisch preparaat die deze bevatten alsmede een inrichting voor het bereiden van eiwit-agglomeraten. |
AU1339701A (en) | 1999-10-22 | 2001-05-08 | Lifespan Biosciences, Inc. | Anti-cancer nucleic acid and protein targets |
AUPR201500A0 (en) | 2000-12-11 | 2001-01-11 | Biosceptre Pty Ltd | Methods for identifying pre-neoplastic and neoplastic states in mammals |
DE60230482D1 (de) | 2001-01-17 | 2009-02-05 | Intreat Pty Ltd | Antikörper gegen nichtfunktionelle p 2 x 7 rezeptoren, diagnose und behandlung von krebs und anderen leiden |
NZ565994A (en) * | 2001-09-03 | 2010-02-26 | Intreat Pty Ltd | Antibodies to non-functional P2X7 receptor, diagnosis and treatment of cancers and other conditions |
MXPA05011008A (es) | 2003-04-17 | 2006-03-08 | Affectis Pharmaceuticals Ag | Medios y metodos para diagnosticar y tratar trastornos afectivos. |
LT2163260T (lt) | 2004-01-23 | 2017-06-26 | Msd Italia S.R.L. | Šimpanzės adenoviruso vakcinos nešikliai |
US7858323B2 (en) * | 2004-06-09 | 2010-12-28 | The Regents Of The University Of Michigan | Phage microarray profiling of the humoral response to disease |
GB0419295D0 (en) * | 2004-08-31 | 2004-09-29 | Genomica Sau | Methods and compositions to prevent neuronal degeneration |
EP1885376A1 (en) | 2005-05-05 | 2008-02-13 | Medicure International Inc. | Inhibition of atp-mediated, p2x7 dependent pathways by pyridoxal-5-phosphaste and vitamin b6 related compounds |
US7767789B2 (en) * | 2005-06-02 | 2010-08-03 | University Hopitals of Cleveland | Truncated proteins as cancer markers |
EP1929305A2 (en) | 2005-08-31 | 2008-06-11 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in leukemia signaling pathways |
JP2010505426A (ja) | 2006-10-10 | 2010-02-25 | バイオスセプター インターナショナル リミテッド | 非機能性p2x7受容体に対する抗体を産生するハイブリドーマ |
US20100036101A1 (en) | 2006-10-10 | 2010-02-11 | Angus Gidley-Baird | Antibodies against non functional p2x7 receptor |
NZ583894A (en) * | 2007-09-14 | 2013-01-25 | Biosceptre Int Ltd | Antibodies that bind to a non atp binding p2x7 receptor |
AU2008299594B2 (en) | 2007-09-14 | 2013-10-03 | Biosceptre International Limited | Purinergic (P2X) receptors in extra-cellular body fluid |
CA2729868C (en) | 2008-07-04 | 2018-07-10 | Biosceptre International Limited | Anti- p2x7 peptides and epitopes |
ES2639577T3 (es) * | 2008-12-10 | 2017-10-27 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Vacuna para la prevención de la recurrencia del cáncer de mama |
EP2966090B1 (en) | 2009-08-20 | 2018-10-10 | Biosceptre (Aust) Pty Ltd | Anti p2x7 receptor antibodies and fragments thereof |
ES2667003T3 (es) * | 2009-12-24 | 2018-05-09 | Biosceptre (Aust) Pty Ltd | Anticuerpos para receptores P2X7 oligoméricos no funcionales |
US8828944B2 (en) | 2010-04-22 | 2014-09-09 | Institut Gustave Roussy | Compounds and uses thereof to induce an immunogenic cancer cell death in a subject |
EP2613808B1 (en) | 2010-09-10 | 2017-11-08 | Biosceptre (Aust) Pty Ltd | Companion animal cancer treatments with an anti p2x7 antibody |
CA2840251C (en) | 2011-07-01 | 2023-09-12 | Biosceptre International Limited | Combination therapy of diseases that are associated with non-functional p2x7 receptor expression |
-
2012
- 2012-07-02 CA CA2840251A patent/CA2840251C/en active Active
- 2012-07-02 MX MX2014000199A patent/MX349321B/es active IP Right Grant
- 2012-07-02 ES ES12807960.5T patent/ES2689272T3/es active Active
- 2012-07-02 AU AU2012278921A patent/AU2012278921B2/en active Active
- 2012-07-02 US US14/129,240 patent/US9566318B2/en active Active
- 2012-07-02 EP EP12807960.5A patent/EP2726095B1/en active Active
- 2012-07-02 BR BR112013033974A patent/BR112013033974A2/pt not_active Application Discontinuation
- 2012-07-02 CN CN201280033124.9A patent/CN103702683B/zh active Active
- 2012-07-02 WO PCT/AU2012/000795 patent/WO2013003895A1/en active Application Filing
- 2012-07-02 JP JP2014517338A patent/JP6305920B2/ja active Active
-
2014
- 2014-01-07 ZA ZA2014/00120A patent/ZA201400120B/en unknown
-
2017
- 2017-01-05 US US15/399,337 patent/US10245308B2/en active Active
-
2018
- 2018-03-06 JP JP2018039564A patent/JP6490270B2/ja active Active
-
2019
- 2019-02-05 US US16/268,344 patent/US10543262B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN103702683B (zh) | 2017-07-04 |
JP6490270B2 (ja) | 2019-03-27 |
BR112013033974A2 (pt) | 2017-02-14 |
US9566318B2 (en) | 2017-02-14 |
US10245308B2 (en) | 2019-04-02 |
JP2018087249A (ja) | 2018-06-07 |
AU2012278921A1 (en) | 2014-01-16 |
CA2840251C (en) | 2023-09-12 |
CN103702683A (zh) | 2014-04-02 |
US10543262B2 (en) | 2020-01-28 |
EP2726095A4 (en) | 2015-01-07 |
AU2012278921B2 (en) | 2016-11-10 |
WO2013003895A1 (en) | 2013-01-10 |
US20170157229A1 (en) | 2017-06-08 |
JP6305920B2 (ja) | 2018-04-04 |
ES2689272T3 (es) | 2018-11-13 |
MX2014000199A (es) | 2014-06-11 |
CA2840251A1 (en) | 2013-01-10 |
EP2726095A1 (en) | 2014-05-07 |
US20190224290A1 (en) | 2019-07-25 |
US20150004179A1 (en) | 2015-01-01 |
EP2726095B1 (en) | 2018-06-06 |
ZA201400120B (en) | 2015-09-30 |
JP2014520759A (ja) | 2014-08-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |