JP2013126996A5 - - Google Patents

Download PDF

Info

Publication number
JP2013126996A5
JP2013126996A5 JP2013027633A JP2013027633A JP2013126996A5 JP 2013126996 A5 JP2013126996 A5 JP 2013126996A5 JP 2013027633 A JP2013027633 A JP 2013027633A JP 2013027633 A JP2013027633 A JP 2013027633A JP 2013126996 A5 JP2013126996 A5 JP 2013126996A5
Authority
JP
Japan
Prior art keywords
mir
usa
cells
dilution
differentiation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013027633A
Other languages
English (en)
Japanese (ja)
Other versions
JP5796027B2 (ja
JP2013126996A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2013126996A publication Critical patent/JP2013126996A/ja
Publication of JP2013126996A5 publication Critical patent/JP2013126996A5/ja
Application granted granted Critical
Publication of JP5796027B2 publication Critical patent/JP5796027B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013027633A 2005-12-12 2013-02-15 筋細胞増殖及び分化を調節するマイクロｒｎａ Expired - Fee Related JP5796027B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74954405P 2005-12-12 2005-12-12
US60/749,544 2005-12-12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2008545718A Division JP2009519339A (ja) 2005-12-12 2006-12-12 筋細胞増殖及び分化を調節するマイクロｒｎａ

Publications (3)

Publication Number Publication Date
JP2013126996A JP2013126996A (ja) 2013-06-27
JP2013126996A5 true JP2013126996A5 (https=) 2014-01-30
JP5796027B2 JP5796027B2 (ja) 2015-10-21

Family

ID=38163464

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2008545718A Pending JP2009519339A (ja) 2005-12-12 2006-12-12 筋細胞増殖及び分化を調節するマイクロｒｎａ
JP2013027633A Expired - Fee Related JP5796027B2 (ja) 2005-12-12 2013-02-15 筋細胞増殖及び分化を調節するマイクロｒｎａ
JP2013253829A Expired - Fee Related JP5740460B2 (ja) 2005-12-12 2013-12-09 筋細胞増殖及び分化を調節するマイクロｒｎａ

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2008545718A Pending JP2009519339A (ja) 2005-12-12 2006-12-12 筋細胞増殖及び分化を調節するマイクロｒｎａ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013253829A Expired - Fee Related JP5740460B2 (ja) 2005-12-12 2013-12-09 筋細胞増殖及び分化を調節するマイクロｒｎａ

Country Status (14)

Country Link
US (3) US8431542B2 (https=)
EP (3) EP2671949A1 (https=)
JP (3) JP2009519339A (https=)
KR (2) KR20140130562A (https=)
CN (2) CN104027818A (https=)
AU (1) AU2006326517B2 (https=)
BR (1) BRPI0619755A2 (https=)
CA (2) CA2634046A1 (https=)
DK (1) DK1969125T3 (https=)
ES (1) ES2387250T3 (https=)
NZ (3) NZ593688A (https=)
PL (1) PL1969125T3 (https=)
PT (1) PT1969125E (https=)
WO (1) WO2007070483A2 (https=)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006107826A2 (en) * 2005-04-04 2006-10-12 The Board Of Regents Of The University Of Texas System Micro-rna's that regulate muscle cells
PL1969125T3 (pl) 2005-12-12 2012-11-30 Univ North Carolina Chapel Hill Mikrorna, które regulują proliferację i różnicowanie komórek mięśniowych
KR101485495B1 (ko) 2006-08-01 2015-01-22 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 베타-마이오신 중사슬의 발현을 활성화하는 마이크로-ｒｎａ의 동정
GB2440782A (en) * 2006-08-04 2008-02-13 Cesare Peschle Uses and compositions comprising miRNAs
EP3342415B1 (en) 2006-08-08 2022-01-26 Rheinische Friedrich-Wilhelms-Universität Bonn Structure and use of 5' phosphate oligonucleotides
CN102149826A (zh) 2007-06-29 2011-08-10 波士顿生物医药公司 通过微小rna装置进行细菌介导的基因调节
AU2008283795B2 (en) * 2007-07-31 2013-11-21 Board Of Regents, The University Of Texas System A micro-RNA family that modulates fibrosis and uses thereof
WO2009018492A2 (en) 2007-07-31 2009-02-05 The Board Of Regents Of The University Of Texas System Micro-rnas that control myosin expression and myofiber identity
WO2009105759A2 (en) * 2008-02-21 2009-08-27 The Board Of Regents Of The University Of Texas System Micro-rnas that modulate smooth muscle proliferation and differentiation and uses thereof
CA2718520C (en) * 2008-03-17 2020-01-07 The Board Of Regents Of The University Of Texas System Identification of micro-rnas involved in neuromuscular synapse maintenance and regeneration
EP2297323A1 (en) 2008-05-21 2011-03-23 Hartmann, Gunther 5' triphosphate oligonucleotide with blunt end and uses thereof
AU2009257663B2 (en) 2008-06-09 2014-06-26 New York Medical College Compositions comprising cardiac stem cells overexpressing specific microRNA and methods of their use in repairing damaged myocardium
GB0811715D0 (en) * 2008-06-26 2008-07-30 Angeletti P Ist Richerche Bio Therapeutic agents
CN102356162A (zh) 2009-02-04 2012-02-15 得克萨斯系统大学董事会 Mir-208和mir-499在治疗心脏病症中的双重靶向
JP5883381B2 (ja) 2009-05-05 2016-03-15 ミラゲン セラピューティクス，インコーポレイテッド 親油性ポリヌクレオチド接合体
US20120059159A1 (en) * 2009-05-25 2012-03-08 Carola Ponzetto Differentiation therapy for sarcomas
EP2540829B1 (en) * 2010-02-26 2015-11-25 Lsip, Llc Marker for detection of myogenic diseases, and method for detection of the diseases using same
US8975021B2 (en) * 2010-04-08 2015-03-10 Kyoto Prefectural Public University Corporation Method for detecting rhabdomyosarcoma using sample derived from body fluid
CA2804791C (en) 2010-07-08 2019-07-30 Duke University Direct reprogramming of cells to cardiac myocyte fate
KR101235256B1 (ko) * 2010-09-13 2013-02-21 서울대학교산학협력단 ｍｉＲＮＡ를 타겟으로 한 신경퇴행성 질환 치료
WO2012061810A1 (en) * 2010-11-05 2012-05-10 Miragen Therapeutics Base modified oligonucleotides
EP2638158A4 (en) * 2010-11-11 2015-07-15 Univ Miami COMPOSITIONS, CELLS, KITS AND METHODS FOR AUTOLOGOUS STEM CELL THERAPY
EA201370139A1 (ru) 2010-12-15 2013-10-30 Мираген Терапеутикс Ингибиторы микро-рнк, содержащие закрытые нуклеотиды
EP2508530A1 (en) 2011-03-28 2012-10-10 Rheinische Friedrich-Wilhelms-Universität Bonn Purification of triphosphorylated oligonucleotides using capture tags
EP2707485B1 (en) * 2011-05-09 2016-12-14 The University Court of The University Of Glasgow Methods of modulating micrornas in the treatment of pulmonary arterial hypertension
US20140221464A1 (en) * 2011-07-01 2014-08-07 Board Of Regents, The University Of Texas System Compositions and Methods for Treating Skeletal Myopathy
US20140259192A1 (en) * 2011-07-12 2014-09-11 Sanofi Transgenic animal comprising a deletion or functional deletion of the 3'utr of an endogenous gene
EP2755663A4 (en) 2011-09-13 2015-10-07 Ottawa Hospital Res Inst MicroRNA Inhibitors
WO2013052965A2 (en) 2011-10-06 2013-04-11 Miragen Therapeutics Control of whole body energy homeostasis by microrna regulation
US9388408B2 (en) 2012-06-21 2016-07-12 MiRagen Therapeutics, Inc. Oligonucleotide-based inhibitors comprising locked nucleic acid motif
EP2712870A1 (en) 2012-09-27 2014-04-02 Rheinische Friedrich-Wilhelms-Universität Bonn Novel RIG-I ligands and methods for producing them
CN105188715B (zh) 2013-03-15 2018-12-25 米拉根医疗股份有限公司 Mir-145的锁定核酸抑制剂及其用途
CA2902571A1 (en) 2013-03-15 2014-09-18 MiRagen Therapeutics, Inc. Bridged bicyclic nucleosides
WO2014201254A1 (en) * 2013-06-12 2014-12-18 University Of Washington Through Its Center For Commercialization Methods for maturing cardiomyocytes and uses thereof
CN103710387B (zh) * 2013-12-25 2015-10-14 天津农学院 一种促进牛骨骼肌卫星细胞体外增殖的方法
JP6566536B2 (ja) * 2014-06-16 2019-08-28 国立大学法人山口大学 フォワードプライマー
CN104498497A (zh) * 2014-12-10 2015-04-08 山东农业大学 一种与奶山羊乳腺上皮细胞凋亡相关的miRNA及其在奶山羊育种中的应用
EP3246398B1 (en) * 2015-01-14 2021-06-16 Kyoto University Method for selecting skeletal muscle progenitor cell
US9885042B2 (en) 2015-01-20 2018-02-06 MiRagen Therapeutics, Inc. miR-92 inhibitors and uses thereof
CN104877960B (zh) * 2015-06-01 2017-09-19 东北农业大学 miR‑2400显著促进牛骨骼肌卫星细胞增殖的生物功能
DK3426781T3 (da) * 2016-03-07 2024-09-30 Us Health Mikro-rna'er og fremgangsmåder til anvendelse deraf
CN105713972A (zh) * 2016-03-16 2016-06-29 上海中医药大学 miRNA在制备药物性心脏病生物标志物中的用途
CN106399473B (zh) * 2016-08-23 2019-12-06 南京大学 检测和评价力量训练效果的miRNA标志物或其组合及其应用
US10934543B2 (en) 2016-10-13 2021-03-02 National Center Of Neurology And Psychiatry Inducer of muscle differentiation
WO2018080658A1 (en) 2016-10-27 2018-05-03 Aalborg University Therapeutic targeting of a microrna to treat duchenne muscular dystrophy
CN108324946B (zh) * 2017-01-20 2022-02-18 上海市东方医院 miRNA708、和/或301簇的微小RNA在改善心脏功能方面的应用
CN107096030A (zh) * 2017-03-20 2017-08-29 天津农学院 一种利用miR‑143抑制剂延缓小鼠失神经后肌肉萎缩的方法
US11365412B2 (en) 2017-04-05 2022-06-21 University Of Cincinnati Promotion of cardiomyocyte proliferation and regenerative treatment of the heart by inhibition of microRNA-128
KR102177130B1 (ko) 2017-08-18 2020-11-10 (주)큐라미스 근육 질환 및 신경근육 질환 예방, 치료 또는 진단을 위한 miR-18b의 용도
WO2019035690A1 (ko) * 2017-08-18 2019-02-21 서울대학교병원 근육 질환 및 신경근육 질환 예방, 치료 또는 진단을 위한 miR-18b의 용도
KR20200096610A (ko) * 2017-12-08 2020-08-12 유니버시티 오브 워싱톤 카르디올리핀 리모델링 및 심근세포 성숙을 검출 및 촉진하기 위한 방법 및 조성물 및 미토콘드리아 기능장애를 치료하는 관련 방법
BR112020018705A2 (pt) * 2018-03-14 2021-01-05 Beth Israel Deaconess Medical Center Inibidores de microrna 22
CN108690846A (zh) * 2018-04-17 2018-10-23 上海大学 抑制MiR-29b基因表达的应用
CN108823209B (zh) * 2018-07-18 2021-04-09 华中农业大学 骨骼肌特异性启动子及应用
CA3111076A1 (en) 2018-08-30 2020-03-05 Tenaya Therapeutics, Inc. Cardiac cell reprogramming with myocardin and ascl1
CN111041052B (zh) * 2019-12-30 2021-05-28 嘉兴学院 mir-206在抑制猪脂肪细胞内的甘油三酯生成以及瘦肉猪育种中的应用
US20230103731A1 (en) * 2020-03-02 2023-04-06 Tenaya Therapeutics, Inc. Gene vector control by cardiomyocyte-expressed micrornas
CA3174286A1 (en) 2020-04-02 2021-10-07 Robert PLACE Targeted inhibition using engineered oligonucleotides
CN112266912A (zh) * 2020-10-22 2021-01-26 上海大学 靶向miR-29b的gRNA、AAV8-CRISPR/Cas9系统及其应用
WO2023034966A1 (en) * 2021-09-03 2023-03-09 The University Of North Carolina At Chapel Hill Compositions and methods of using the same for treating disorders associated with thymosin βeta 4
CN114480672B (zh) * 2022-02-22 2023-08-15 青岛农业大学 一种通过miR-145筛选高产肉率碱地黑牛的方法
CN114748497B (zh) * 2022-04-27 2024-10-18 广州市妇女儿童医疗中心 一种调控子宫肌收缩的miRNA分子miR-206及其应用
CN115181722B (zh) * 2022-08-30 2024-06-11 江苏农牧科技职业学院 一种鹅骨骼肌卫星细胞的体外分离和培养方法
CN117511884B (zh) * 2023-12-06 2024-06-11 中国农业科学院兰州畜牧与兽药研究所 Rtl1在抑制牦牛成肌细胞分化中的应用
KR20250173053A (ko) * 2024-05-31 2025-12-10 충남대학교산학협력단 전구체 miRNA를 포함하는 근육 감소 또는 근육 위축 예방, 개선 또는 치료용 조성물
KR20250173054A (ko) * 2024-05-31 2025-12-10 충남대학교산학협력단 전구체 miRNA를 포함하는 근육 감소 또는 근육 위축 진단용 바이오마커 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7803782B2 (en) * 2003-05-28 2010-09-28 Roche Madison Inc. Intravenous delivery of polynucleotides to cells in mammalian limb
US20050124566A1 (en) * 2001-05-18 2005-06-09 Sirna Therapeutics, Inc. RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
EP2390331B1 (en) * 2001-09-28 2018-04-25 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. MicroRNA molecules
US7781415B2 (en) * 2003-02-07 2010-08-24 Roche Madison Inc. Process for delivering sirna to cardiac muscle tissue
JP2006519008A (ja) * 2003-02-10 2006-08-24 独立行政法人産業技術総合研究所 哺乳動物細胞の調節
SE0300500L (sv) * 2003-02-26 2003-11-18 Scania Cv Publ Kraftöverföring med från en huvudväxel skild rangeväxel
CA2857881A1 (en) * 2004-11-12 2006-12-28 Asuragen, Inc. Methods and compositions involving mirna and mirna inhibitor molecules
WO2006107826A2 (en) * 2005-04-04 2006-10-12 The Board Of Regents Of The University Of Texas System Micro-rna's that regulate muscle cells
US7338670B2 (en) 2005-04-14 2008-03-04 Duke University Use of an agent that restores tissue perfusion and oxygenation
PL1969125T3 (pl) 2005-12-12 2012-11-30 Univ North Carolina Chapel Hill Mikrorna, które regulują proliferację i różnicowanie komórek mięśniowych

Similar Documents

Publication Publication Date Title
JP2013126996A5 (https=)
Javanmardi et al. miR-21, an oncogenic target miRNA for cancer therapy: molecular mechanisms and recent advancements in chemo and radio-resistance
Zhou et al. Linc-RNA-RoR acts as a “sponge” against mediation of the differentiation of endometrial cancer stem cells by microRNA-145
Deng et al. MicroRNA-195 and microRNA-378 mediate tumor growth suppression by epigenetical regulation in gastric cancer
Esau Inhibition of microRNA with antisense oligonucleotides
Charrier et al. Connective tissue growth factor (CCN2) and microRNA-21 are components of a positive feedback loop in pancreatic stellate cells (PSC) during chronic pancreatitis and are exported in PSC-derived exosomes
Huang et al. MicroRNA-21: a central regulator of fibrotic diseases via various targets
JP5898843B2 (ja) 血管新生、血管形成、若しくは血管修復を促進するか、又は腫瘍血管新生を阻害する方法
Yan et al. Inhibition of miR-222-3p activity promoted osteogenic differentiation of hBMSCs by regulating Smad5-RUNX2 signal axis
Brock et al. The hypoxia-induced microRNA-130a controls pulmonary smooth muscle cell proliferation by directly targeting CDKN1A
Wei et al. microRNA‐151–3p Regulates Slow Muscle Gene Expression by Targeting ATP2a2 in Skeletal Muscle Cells
Cai et al. Gold nano-particles (AuNPs) carrying anti-EBV-miR-BART7-3p inhibit growth of EBV-positive nasopharyngeal carcinoma
Wu et al. MicroRNA-214 regulates smooth muscle cell differentiation from stem cells by targeting RNA-binding protein QKI
McKenna et al. miR-24 and miR-205 expression is dependent on HPV onco-protein expression in keratinocytes
Jin et al. MiR-1269a acts as an onco-miRNA in non-small cell lung cancer via down-regulating SOX6.
US20140356459A1 (en) Micrornas and uses thereof
Li et al. miR-339-5p inhibits metastasis of non-small cell lung cancer by regulating the epithelial-to-mesenchymal transition
López et al. Differential effects of miR-34c-3p and miR-34c-5p on SiHa cells proliferation apoptosis, migration and invasion
Wang et al. Double-stranded Let-7 mimics, potential candidates for cancer gene therapy
Yu et al. miR-208-3p promotes hepatocellular carcinoma cell proliferation and invasion through regulating ARID2 expression
Liu et al. DICER-dependent biogenesis of let-7 miRNAs affects human cell response to DNA damage via targeting p21/p27
Guifan et al. miR-1246 shuttling from fibroblasts promotes colorectal cancer cell migration.
CN104726500A (zh) MicroRNA26b-3p抑制剂在制备人脐带来源间充质干细胞中的应用
Lou et al. miR-21 down-regulation promotes apoptosis and inhibits invasion and migration abilities of OVCAR3 cells
Kang et al. Macro and small over micro: macromolecules and small molecules that regulate microRNAs