JP2012529272A5 - - Google Patents
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- Publication number
- JP2012529272A5 JP2012529272A5 JP2012514307A JP2012514307A JP2012529272A5 JP 2012529272 A5 JP2012529272 A5 JP 2012529272A5 JP 2012514307 A JP2012514307 A JP 2012514307A JP 2012514307 A JP2012514307 A JP 2012514307A JP 2012529272 A5 JP2012529272 A5 JP 2012529272A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- angiopep
- disease
- compound according
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18624609P | 2009-06-11 | 2009-06-11 | |
| US61/186,246 | 2009-06-11 | ||
| PCT/CA2010/000889 WO2010142035A1 (en) | 2009-06-11 | 2010-06-11 | Fusion proteins for delivery of gdnf and bdnf to the central nervous system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012529272A JP2012529272A (ja) | 2012-11-22 |
| JP2012529272A5 true JP2012529272A5 (enExample) | 2013-07-25 |
Family
ID=43308346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012514307A Pending JP2012529272A (ja) | 2009-06-11 | 2010-06-11 | Gdnfおよびbdnfを中枢神経系へ送達するための融合タンパク質 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20120196803A1 (enExample) |
| EP (1) | EP2440581A4 (enExample) |
| JP (1) | JP2012529272A (enExample) |
| CN (2) | CN102459348A (enExample) |
| AU (1) | AU2010258052A1 (enExample) |
| BR (1) | BRPI1012971A2 (enExample) |
| CA (1) | CA2764777A1 (enExample) |
| MX (1) | MX2011013258A (enExample) |
| WO (1) | WO2010142035A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1747747B (zh) | 2003-01-06 | 2012-09-05 | 安吉奥开米公司 | 作为穿过血脑屏障的载体的抑酶肽及类似物 |
| JP5436856B2 (ja) | 2005-07-15 | 2014-03-05 | アンジオケム インコーポレーティッド | 薬学的複合体における担体としてのアプロチニンポリペプチドの使用 |
| EP2074142A4 (en) | 2006-10-19 | 2010-10-27 | Angiochem Inc | COMPOUNDS FOR STIMULATING THE FUNCTION OF P-GLYCOPROTEIN AND APPLICATIONS THEREOF |
| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| US8921314B2 (en) | 2008-10-15 | 2014-12-30 | Angiochem, Inc. | Conjugates of GLP-1 agonists and uses thereof |
| MX2011005963A (es) | 2008-12-05 | 2011-09-01 | Angiochem Inc | Conjugados de neurotensina o analogos de neurotensina y sus usos. |
| CN102300987A (zh) | 2008-12-17 | 2011-12-28 | 安吉奥开米公司 | 膜型-1基质金属蛋白抑制剂及其用途 |
| AU2010239069B2 (en) | 2009-04-20 | 2015-05-14 | Angiochem Inc | Treatment of ovarian cancer using an anticancer agent conjugated to an Angiopep-2 analog |
| MX2012000016A (es) | 2009-07-02 | 2012-03-26 | Angiochem Inc | Conjugados de peptidos multimericos y sus usos. |
| WO2011153642A1 (en) * | 2010-06-10 | 2011-12-15 | Angiochem Inc. | Leptin and leptin analog conjugates and fusion proteins and uses thereof |
| RU2013103763A (ru) | 2010-07-02 | 2014-08-10 | Ангиохем Инк. | Короткие и содержащие d-аминокислоты полипептиды для терапевтических конъюгатов и их применения |
| WO2014026283A1 (en) | 2012-08-14 | 2014-02-20 | Angiochem Inc. | Peptide-dendrimer conjugates and uses thereof |
| JP6234331B2 (ja) * | 2014-06-13 | 2017-11-22 | 森永乳業株式会社 | 統合失調症治療剤 |
| US10980892B2 (en) | 2015-06-15 | 2021-04-20 | Angiochem Inc. | Methods for the treatment of leptomeningeal carcinomatosis |
| AU2017263174A1 (en) | 2016-05-13 | 2018-12-13 | Instituto de Medicina Molecular João Lobo Antunes | Methods of treating diseases associated with ILC3 cells |
| US11912750B2 (en) | 2016-11-10 | 2024-02-27 | Keros Therapeutics, Inc. | GDNF fusion polypeptides and methods of use thereof |
| CN107141354A (zh) * | 2017-05-05 | 2017-09-08 | 李斯文 | 一种融合蛋白及光敏剂复合物及其制备方法和应用 |
| KR20210012966A (ko) * | 2019-07-24 | 2021-02-03 | 주식회사 에스엘바이젠 | 불사화된 줄기세포주의 제조 방법 및 이의 용도 |
| JP2024522938A (ja) | 2021-06-03 | 2024-06-21 | フンダサン デー.アンナ ジ ソーメル チャンパリマウド エー ドクトル カルロス モンテス チャンパリマウド | 脳-脂肪回路を介してilc2および肥満度を制御する神経-間葉単位 |
| CN116270429B (zh) * | 2023-02-17 | 2025-06-10 | 山东省药学科学院 | 一种鼻黏膜给药的抗抑郁制剂及其制备方法和应用 |
| CN120077136A (zh) * | 2023-09-28 | 2025-05-30 | 广州必贝特医药股份有限公司 | 抑制淀粉样前体蛋白(APP)基因表达的siRNA、药物及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101160403B (zh) * | 2005-02-18 | 2014-08-13 | 安吉奥开米公司 | 转运化合物穿过血脑屏障的分子 |
| US20090016959A1 (en) * | 2005-02-18 | 2009-01-15 | Richard Beliveau | Delivery of antibodies to the central nervous system |
| US8053569B2 (en) * | 2005-10-07 | 2011-11-08 | Armagen Technologies, Inc. | Nucleic acids encoding and methods of producing fusion proteins |
| EP2789628A3 (en) * | 2007-05-29 | 2015-03-04 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| US8802631B2 (en) * | 2007-09-17 | 2014-08-12 | Ludwig Institute For Cancer Research Ltd. | Peptides and methods for the treatment of gliomas and other cancers |
| WO2009070597A2 (en) * | 2007-11-26 | 2009-06-04 | Armagen Technologies, Inc. | Fusion proteins for delivery of gdnf to the cns |
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2010
- 2010-06-11 AU AU2010258052A patent/AU2010258052A1/en not_active Abandoned
- 2010-06-11 MX MX2011013258A patent/MX2011013258A/es not_active Application Discontinuation
- 2010-06-11 WO PCT/CA2010/000889 patent/WO2010142035A1/en not_active Ceased
- 2010-06-11 US US13/377,480 patent/US20120196803A1/en not_active Abandoned
- 2010-06-11 JP JP2012514307A patent/JP2012529272A/ja active Pending
- 2010-06-11 CN CN2010800317596A patent/CN102459348A/zh active Pending
- 2010-06-11 EP EP10785633A patent/EP2440581A4/en not_active Withdrawn
- 2010-06-11 BR BRPI1012971A patent/BRPI1012971A2/pt not_active IP Right Cessation
- 2010-06-11 CA CA2764777A patent/CA2764777A1/en not_active Abandoned
- 2010-06-11 CN CN201410030902.XA patent/CN103819564A/zh active Pending