JP2012529272A5 - - Google Patents
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- Publication number
- JP2012529272A5 JP2012529272A5 JP2012514307A JP2012514307A JP2012529272A5 JP 2012529272 A5 JP2012529272 A5 JP 2012529272A5 JP 2012514307 A JP2012514307 A JP 2012514307A JP 2012514307 A JP2012514307 A JP 2012514307A JP 2012529272 A5 JP2012529272 A5 JP 2012529272A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- angiopep
- disease
- compound according
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18624609P | 2009-06-11 | 2009-06-11 | |
| US61/186,246 | 2009-06-11 | ||
| PCT/CA2010/000889 WO2010142035A1 (en) | 2009-06-11 | 2010-06-11 | Fusion proteins for delivery of gdnf and bdnf to the central nervous system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012529272A JP2012529272A (ja) | 2012-11-22 |
| JP2012529272A5 true JP2012529272A5 (enExample) | 2013-07-25 |
Family
ID=43308346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012514307A Pending JP2012529272A (ja) | 2009-06-11 | 2010-06-11 | Ｇｄｎｆおよびｂｄｎｆを中枢神経系へ送達するための融合タンパク質 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20120196803A1 (enExample) |
| EP (1) | EP2440581A4 (enExample) |
| JP (1) | JP2012529272A (enExample) |
| CN (2) | CN103819564A (enExample) |
| AU (1) | AU2010258052A1 (enExample) |
| BR (1) | BRPI1012971A2 (enExample) |
| CA (1) | CA2764777A1 (enExample) |
| MX (1) | MX2011013258A (enExample) |
| WO (1) | WO2010142035A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4903036B2 (ja) | 2003-01-06 | 2012-03-21 | アンジオケム・インコーポレーテッド | 血液脳関門を通過する担体としてのアプロチニンおよび類似体 |
| WO2007009229A1 (en) | 2005-07-15 | 2007-01-25 | Angiochem Inc. | Use of aprotinin polypeptides as carriers in pharmaceutical conjugates |
| EP2074142A4 (en) | 2006-10-19 | 2010-10-27 | Angiochem Inc | COMPOUNDS FOR STIMULATING THE FUNCTION OF P-GLYCOPROTEIN AND APPLICATIONS THEREOF |
| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| WO2010043047A1 (en) | 2008-10-15 | 2010-04-22 | Angiochem Inc. | Conjugates of glp-1 agonists and uses thereof |
| US9914754B2 (en) | 2008-12-05 | 2018-03-13 | Angiochem Inc. | Conjugates of neurotensin or neurotensin analogs and uses thereof |
| AU2009327267A1 (en) | 2008-12-17 | 2011-07-14 | Angiochem, Inc. | Membrane type-1 matrix metalloprotein inhibitors and uses thereof |
| ES2729261T3 (es) | 2009-04-20 | 2019-10-31 | Angiochem Inc | Tratamiento del cáncer de ovario utilizando un agente anticancerígeno conjugado con un análogo de Angiopep-2 |
| WO2011000095A1 (en) | 2009-07-02 | 2011-01-06 | Angiochem Inc. | Multimeric peptide conjugates and uses thereof |
| WO2011153642A1 (en) * | 2010-06-10 | 2011-12-15 | Angiochem Inc. | Leptin and leptin analog conjugates and fusion proteins and uses thereof |
| MX2013000250A (es) * | 2010-07-02 | 2013-10-28 | Angiochem Inc | Polipeptidos cortos y que contienen d-aminoacido para conjugados terapeuticos y usos de los mismos. |
| JP2015526434A (ja) | 2012-08-14 | 2015-09-10 | アンジオケム インコーポレーテッド | ペプチド−デンドリマーコンジュゲート及びその使用 |
| JP6234331B2 (ja) * | 2014-06-13 | 2017-11-22 | 森永乳業株式会社 | 統合失調症治療剤 |
| EP3307326B9 (en) | 2015-06-15 | 2021-02-24 | Angiochem Inc. | Methods for the treatment of leptomeningeal carcinomatosis |
| JP7000349B2 (ja) | 2016-05-13 | 2022-02-04 | インスティテュート デ メディシナ モレキュラー ジョアオ ロボ アントゥネス | Ｉｌｃ３細胞に関連する疾患を処置する方法 |
| AU2017357931B2 (en) | 2016-11-10 | 2024-12-05 | Keros Therapeutics, Inc. | GDNF fusion polypeptides and methods of use thereof |
| CN107141354A (zh) * | 2017-05-05 | 2017-09-08 | 李斯文 | 一种融合蛋白及光敏剂复合物及其制备方法和应用 |
| WO2021015584A1 (ko) * | 2019-07-24 | 2021-01-28 | 주식회사 에스엘바이젠 | 불사화된 줄기세포주의 제조 방법 및 이의 용도 |
| JP2024522938A (ja) | 2021-06-03 | 2024-06-21 | フンダサン デー．アンナ ジ ソーメル チャンパリマウド エー ドクトル カルロス モンテス チャンパリマウド | 脳－脂肪回路を介してｉｌｃ２および肥満度を制御する神経－間葉単位 |
| CN116270429B (zh) * | 2023-02-17 | 2025-06-10 | 山东省药学科学院 | 一种鼻黏膜给药的抗抑郁制剂及其制备方法和应用 |
| CN120077136A (zh) * | 2023-09-28 | 2025-05-30 | 广州必贝特医药股份有限公司 | 抑制淀粉样前体蛋白（APP）基因表达的siRNA、药物及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0520032A2 (pt) * | 2005-02-18 | 2009-04-14 | Angiochem Inc | moléculas para transportar um composto através da barreira hematoencefálica |
| US20090016959A1 (en) * | 2005-02-18 | 2009-01-15 | Richard Beliveau | Delivery of antibodies to the central nervous system |
| US8142781B2 (en) * | 2005-10-07 | 2012-03-27 | Armagen Technologies, Inc. | Fusion proteins for blood-brain barrier delivery |
| AU2008255556B2 (en) * | 2007-05-29 | 2014-08-07 | Angiochem, Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| US8802631B2 (en) * | 2007-09-17 | 2014-08-12 | Ludwig Institute For Cancer Research Ltd. | Peptides and methods for the treatment of gliomas and other cancers |
| WO2009070597A2 (en) * | 2007-11-26 | 2009-06-04 | Armagen Technologies, Inc. | Fusion proteins for delivery of gdnf to the cns |
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2010
- 2010-06-11 CA CA2764777A patent/CA2764777A1/en not_active Abandoned
- 2010-06-11 MX MX2011013258A patent/MX2011013258A/es not_active Application Discontinuation
- 2010-06-11 WO PCT/CA2010/000889 patent/WO2010142035A1/en not_active Ceased
- 2010-06-11 BR BRPI1012971A patent/BRPI1012971A2/pt not_active IP Right Cessation
- 2010-06-11 JP JP2012514307A patent/JP2012529272A/ja active Pending
- 2010-06-11 US US13/377,480 patent/US20120196803A1/en not_active Abandoned
- 2010-06-11 EP EP10785633A patent/EP2440581A4/en not_active Withdrawn
- 2010-06-11 CN CN201410030902.XA patent/CN103819564A/zh active Pending
- 2010-06-11 CN CN2010800317596A patent/CN102459348A/zh active Pending
- 2010-06-11 AU AU2010258052A patent/AU2010258052A1/en not_active Abandoned