JP2012529272A5 - - Google Patents

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Publication number
JP2012529272A5
JP2012529272A5 JP2012514307A JP2012514307A JP2012529272A5 JP 2012529272 A5 JP2012529272 A5 JP 2012529272A5 JP 2012514307 A JP2012514307 A JP 2012514307A JP 2012514307 A JP2012514307 A JP 2012514307A JP 2012529272 A5 JP2012529272 A5 JP 2012529272A5
Authority
JP
Japan
Prior art keywords
seq
angiopep
disease
compound according
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012514307A
Other languages
English (en)
Japanese (ja)
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JP2012529272A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2010/000889 external-priority patent/WO2010142035A1/en
Publication of JP2012529272A publication Critical patent/JP2012529272A/ja
Publication of JP2012529272A5 publication Critical patent/JP2012529272A5/ja
Pending legal-status Critical Current

Links

JP2012514307A 2009-06-11 2010-06-11 Gdnfおよびbdnfを中枢神経系へ送達するための融合タンパク質 Pending JP2012529272A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18624609P 2009-06-11 2009-06-11
US61/186,246 2009-06-11
PCT/CA2010/000889 WO2010142035A1 (en) 2009-06-11 2010-06-11 Fusion proteins for delivery of gdnf and bdnf to the central nervous system

Publications (2)

Publication Number Publication Date
JP2012529272A JP2012529272A (ja) 2012-11-22
JP2012529272A5 true JP2012529272A5 (enExample) 2013-07-25

Family

ID=43308346

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012514307A Pending JP2012529272A (ja) 2009-06-11 2010-06-11 Gdnfおよびbdnfを中枢神経系へ送達するための融合タンパク質

Country Status (9)

Country Link
US (1) US20120196803A1 (enExample)
EP (1) EP2440581A4 (enExample)
JP (1) JP2012529272A (enExample)
CN (2) CN102459348A (enExample)
AU (1) AU2010258052A1 (enExample)
BR (1) BRPI1012971A2 (enExample)
CA (1) CA2764777A1 (enExample)
MX (1) MX2011013258A (enExample)
WO (1) WO2010142035A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1747747B (zh) 2003-01-06 2012-09-05 安吉奥开米公司 作为穿过血脑屏障的载体的抑酶肽及类似物
JP5436856B2 (ja) 2005-07-15 2014-03-05 アンジオケム インコーポレーティッド 薬学的複合体における担体としてのアプロチニンポリペプチドの使用
EP2074142A4 (en) 2006-10-19 2010-10-27 Angiochem Inc COMPOUNDS FOR STIMULATING THE FUNCTION OF P-GLYCOPROTEIN AND APPLICATIONS THEREOF
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
US8921314B2 (en) 2008-10-15 2014-12-30 Angiochem, Inc. Conjugates of GLP-1 agonists and uses thereof
MX2011005963A (es) 2008-12-05 2011-09-01 Angiochem Inc Conjugados de neurotensina o analogos de neurotensina y sus usos.
CN102300987A (zh) 2008-12-17 2011-12-28 安吉奥开米公司 膜型-1基质金属蛋白抑制剂及其用途
AU2010239069B2 (en) 2009-04-20 2015-05-14 Angiochem Inc Treatment of ovarian cancer using an anticancer agent conjugated to an Angiopep-2 analog
MX2012000016A (es) 2009-07-02 2012-03-26 Angiochem Inc Conjugados de peptidos multimericos y sus usos.
WO2011153642A1 (en) * 2010-06-10 2011-12-15 Angiochem Inc. Leptin and leptin analog conjugates and fusion proteins and uses thereof
RU2013103763A (ru) 2010-07-02 2014-08-10 Ангиохем Инк. Короткие и содержащие d-аминокислоты полипептиды для терапевтических конъюгатов и их применения
WO2014026283A1 (en) 2012-08-14 2014-02-20 Angiochem Inc. Peptide-dendrimer conjugates and uses thereof
JP6234331B2 (ja) * 2014-06-13 2017-11-22 森永乳業株式会社 統合失調症治療剤
US10980892B2 (en) 2015-06-15 2021-04-20 Angiochem Inc. Methods for the treatment of leptomeningeal carcinomatosis
AU2017263174A1 (en) 2016-05-13 2018-12-13 Instituto de Medicina Molecular João Lobo Antunes Methods of treating diseases associated with ILC3 cells
US11912750B2 (en) 2016-11-10 2024-02-27 Keros Therapeutics, Inc. GDNF fusion polypeptides and methods of use thereof
CN107141354A (zh) * 2017-05-05 2017-09-08 李斯文 一种融合蛋白及光敏剂复合物及其制备方法和应用
KR20210012966A (ko) * 2019-07-24 2021-02-03 주식회사 에스엘바이젠 불사화된 줄기세포주의 제조 방법 및 이의 용도
JP2024522938A (ja) 2021-06-03 2024-06-21 フンダサン デー.アンナ ジ ソーメル チャンパリマウド エー ドクトル カルロス モンテス チャンパリマウド 脳-脂肪回路を介してilc2および肥満度を制御する神経-間葉単位
CN116270429B (zh) * 2023-02-17 2025-06-10 山东省药学科学院 一种鼻黏膜给药的抗抑郁制剂及其制备方法和应用
CN120077136A (zh) * 2023-09-28 2025-05-30 广州必贝特医药股份有限公司 抑制淀粉样前体蛋白(APP)基因表达的siRNA、药物及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101160403B (zh) * 2005-02-18 2014-08-13 安吉奥开米公司 转运化合物穿过血脑屏障的分子
US20090016959A1 (en) * 2005-02-18 2009-01-15 Richard Beliveau Delivery of antibodies to the central nervous system
US8053569B2 (en) * 2005-10-07 2011-11-08 Armagen Technologies, Inc. Nucleic acids encoding and methods of producing fusion proteins
EP2789628A3 (en) * 2007-05-29 2015-03-04 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
US8802631B2 (en) * 2007-09-17 2014-08-12 Ludwig Institute For Cancer Research Ltd. Peptides and methods for the treatment of gliomas and other cancers
WO2009070597A2 (en) * 2007-11-26 2009-06-04 Armagen Technologies, Inc. Fusion proteins for delivery of gdnf to the cns

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