|
GB1120945A
(en)
|
1964-08-11 |
1968-07-24 |
Fisons Pharmaceuticals Ltd |
Applicator in combination with a pressurised aerosol dispensing container
|
|
EP0397834B1
(en)
|
1988-10-28 |
2000-02-02 |
Genentech, Inc. |
Method for identifying active domains and amino acid residues in polypeptides and hormone variants
|
|
EP0368684B2
(en)
|
1988-11-11 |
2004-09-29 |
Medical Research Council |
Cloning immunoglobulin variable domain sequences.
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
US5399346A
(en)
|
1989-06-14 |
1995-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Gene therapy
|
|
SE509359C2
(sv)
|
1989-08-01 |
1999-01-18 |
Cemu Bioteknik Ab |
Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
CA2079802C
(en)
|
1990-04-05 |
2001-09-18 |
Roberto Crea |
Walk-through mutagenesis
|
|
EP0605522B1
(en)
|
1991-09-23 |
1999-06-23 |
Medical Research Council |
Methods for the production of humanized antibodies
|
|
AU687010B2
(en)
|
1992-07-17 |
1998-02-19 |
Dana-Farber Cancer Institute |
Method of intracellular binding of target molecules
|
|
DK1621554T4
(da)
|
1992-08-21 |
2012-12-17 |
Univ Bruxelles |
Immunoglobuliner blottet for lette kæder
|
|
JP3626187B2
(ja)
|
1993-06-07 |
2005-03-02 |
バイカル インコーポレイテッド |
遺伝子治療に適するプラスミド
|
|
ES2155854T3
(es)
|
1993-06-09 |
2001-06-01 |
Unilever Nv |
Procedimiento de produccion de proteinas de fusion que comprende fragmentos de scfv con la ayuda de un molde transformado.
|
|
US6091639A
(en)
|
1993-08-27 |
2000-07-18 |
Kabushiki Kaisha Toshiba |
Non-volatile semiconductor memory device and data programming method
|
|
EP0759170B1
(en)
|
1993-09-10 |
2008-07-09 |
The Trustees Of Columbia University In The City Of New York |
Uses of green fluorescent protein
|
|
WO1995021191A1
(en)
|
1994-02-04 |
1995-08-10 |
William Ward |
Bioluminescent indicator based upon the expression of a gene for a modified green-fluorescent protein
|
|
EP0745134A1
(en)
|
1994-02-22 |
1996-12-04 |
Danafarber Cancer Institute |
Nucleic acid delivery system, method of synthesis and uses thereof
|
|
US5625048A
(en)
|
1994-11-10 |
1997-04-29 |
The Regents Of The University Of California |
Modified green fluorescent proteins
|
|
EP0739981A1
(en)
|
1995-04-25 |
1996-10-30 |
Vrije Universiteit Brussel |
Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
|
|
US5693492A
(en)
|
1995-05-05 |
1997-12-02 |
Merck & Co., Inc. |
DNA encoding glutamate gated chloride channels
|
|
US5811524A
(en)
*
|
1995-06-07 |
1998-09-22 |
Idec Pharmaceuticals Corporation |
Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
|
|
CA2225460A1
(en)
|
1995-06-23 |
1997-01-09 |
Winston Campbell Patterson |
Transcriptional regulation of genes encoding vascular endothelial growth factor receptors
|
|
ATE184613T1
(de)
|
1995-09-22 |
1999-10-15 |
Novo Nordisk As |
Varianten des grünen fluoreszenzproteins, gfp
|
|
US6027881A
(en)
|
1996-05-08 |
2000-02-22 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Mutant Aequorea victoria fluorescent proteins having increased cellular fluorescence
|
|
US6020182A
(en)
*
|
1996-07-12 |
2000-02-01 |
Connaught Laboratories Limited |
Subunit respiratory syncytial virus vaccine preparation
|
|
US6124128A
(en)
|
1996-08-16 |
2000-09-26 |
The Regents Of The University Of California |
Long wavelength engineered fluorescent proteins
|
|
EP0977590A4
(en)
*
|
1996-11-01 |
2001-03-14 |
Smithkline Beecham Corp |
HUMAN MONOCLONAL ANTIBODIES
|
|
WO1998021355A1
(en)
|
1996-11-15 |
1998-05-22 |
Life Technologies, Inc. |
Mutants of green fluorescent protein
|
|
AU7298398A
(en)
|
1996-11-19 |
1998-06-10 |
Sangstat Medical Corporation |
Enhanced effects for hapten conjugated therapeutics
|
|
US7122636B1
(en)
|
1997-02-21 |
2006-10-17 |
Genentech, Inc. |
Antibody fragment-polymer conjugates and uses of same
|
|
US6329516B1
(en)
|
1997-04-28 |
2001-12-11 |
Fmc Corporation |
Lepidopteran GABA-gated chloride channels
|
|
FR2766826B1
(fr)
|
1997-08-04 |
2001-05-18 |
Pasteur Institut |
Vecteurs derives d'anticorps pour le transfert de substances dans les cellules
|
|
KR20010034512A
(ko)
|
1998-02-19 |
2001-04-25 |
베렌슨, 론 |
림프구 활성화 조절을 위한 조성물 및 그 방법
|
|
GB9824632D0
(en)
|
1998-11-10 |
1999-01-06 |
Celltech Therapeutics Ltd |
Biological compounds
|
|
CA2361678A1
(en)
|
1999-02-05 |
2000-08-10 |
Rijksuniversiteit Leiden |
Method of modulating metabolite biosynthesis in recombinant cells
|
|
CA2370351A1
(en)
|
1999-04-22 |
2000-11-02 |
Unilever Plc |
Inhibition of viral infection using monovalent antigen-binding proteins
|
|
AR030019A1
(es)
|
1999-05-18 |
2003-08-13 |
Smithkline Beecham Corp |
Anticuerpos monoclonales humanos y fragmentos funcionales del mismo, un procedimiento para su produccion, composiciones farmaceuticas que los comprenden, una molecula aislada de acido nucleico, un plasmido recombinante, una celula hospedante y el uso de dichos anticuerpos para la manufactura de un m
|
|
IL147920A0
(en)
|
1999-08-02 |
2002-08-14 |
Keygene Nv |
Method for generating cgmmv resistant plants, genetic constructs, and the obtained cgmmv-resistant plants
|
|
GB9922124D0
(en)
|
1999-09-17 |
1999-11-17 |
Pfizer Ltd |
Phosphodiesterase enzymes
|
|
US6849425B1
(en)
|
1999-10-14 |
2005-02-01 |
Ixsys, Inc. |
Methods of optimizing antibody variable region binding affinity
|
|
DE19955408A1
(de)
|
1999-11-18 |
2001-05-23 |
Bayer Ag |
GABA-B-Rezeptoren
|
|
EP1240337B1
(en)
|
1999-12-24 |
2006-08-23 |
Genentech, Inc. |
Methods and compositions for prolonging elimination half-times of bioactive compounds
|
|
US6741957B1
(en)
|
2000-07-21 |
2004-05-25 |
Daimlerchrysler Corporation |
Analytical tire model for vehicle durability and ride comfort analysis
|
|
US6818216B2
(en)
|
2000-11-28 |
2004-11-16 |
Medimmune, Inc. |
Anti-RSV antibodies
|
|
US7054297B1
(en)
|
2000-12-28 |
2006-05-30 |
Cisco Technology, Inc. |
Distribution of packets to high data rate communications devices using multicast protocols
|
|
US7829084B2
(en)
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
|
RU2420537C2
(ru)
|
2001-01-17 |
2011-06-10 |
Трабьон Фармасьютикалз Инк. |
Слитые белки связывающий домен-иммуноглобулин
|
|
AU2002335930B2
(en)
|
2001-03-09 |
2005-07-28 |
Morphosys Ag |
Serum albumin binding moieties
|
|
DK1399484T3
(da)
|
2001-06-28 |
2010-11-08 |
Domantis Ltd |
Dobbelt-specifik ligand og anvendelse af denne
|
|
US20060073141A1
(en)
|
2001-06-28 |
2006-04-06 |
Domantis Limited |
Compositions and methods for treating inflammatory disorders
|
|
AU2002355477B2
(en)
|
2001-08-03 |
2008-09-25 |
Medical Research Council |
Method of identifying a consensus sequence for intracellular antibodies
|
|
FR2829940A1
(fr)
|
2001-09-27 |
2003-03-28 |
Synt Em |
Compositions pour la vectorisation d'anticorps a travers la barriere hematoencephalique et leur utilisation pour le diagnostic ou le traitement des maladies du systeme nerveux central
|
|
KR100599789B1
(ko)
|
2001-12-03 |
2006-07-12 |
삼성에스디아이 주식회사 |
방열효율이 향상된 플라즈마 디스플레이 장치 및 그 제조방법
|
|
EP1456410A2
(en)
|
2001-12-11 |
2004-09-15 |
AlgoNomics N.V. |
Method for displaying loops from immunoglobulin domains in different contexts
|
|
EP1461080A2
(en)
|
2001-12-18 |
2004-09-29 |
Innogenetics N.V. |
Purified hepatitis c virus envelope proteins for diagnostic and therapeutic use
|
|
AU2003210060B2
(en)
|
2002-03-22 |
2010-02-25 |
Aprogen, Inc. |
Humanized antibody and process for preparing same
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
AU2003244817B2
(en)
|
2002-06-28 |
2010-08-26 |
Domantis Limited |
Antigen-binding immunoglobulin single variable domains and dual-specific constructs
|
|
US7004940B2
(en)
|
2002-10-10 |
2006-02-28 |
Ethicon, Inc. |
Devices for performing thermal ablation having movable ultrasound transducers
|
|
BRPI0315666B8
(pt)
|
2002-10-23 |
2021-05-25 |
Ludwig Inst For Cancer Res Ltd |
dna de a34 e a33 do tipo 3, proteínas, seus anticorpos e métodos de tratamento usando os mesmos
|
|
EP1558645B1
(en)
|
2002-11-08 |
2011-07-27 |
Ablynx N.V. |
Stabilized single domain antibodies in pharmaceutical composition adapted for inhalation
|
|
WO2004041863A2
(en)
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Single domain antibodies directed against interferon- gamma and uses therefor
|
|
GB0230203D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
|
MXPA05007151A
(es)
|
2002-12-31 |
2005-09-21 |
Nektar Therapeutics Al Corp |
Polimeros terminados en maleimida hidroliticamente estables.
|
|
JP2006517789A
(ja)
|
2003-01-10 |
2006-08-03 |
アブリンクス エン．ヴェー． |
治療用ポリペプチド、その相同物、その断片、および血小板媒介凝集の調節での使用
|
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
|
US7070786B2
(en)
|
2003-06-06 |
2006-07-04 |
Centocor, Inc. |
RSV proteins, antibodies, compositions, methods and uses
|
|
BRPI0412007A
(pt)
|
2003-06-27 |
2006-08-15 |
Bioren Inc |
mutagênese look-through
|
|
KR101044544B1
(ko)
|
2003-06-30 |
2011-06-27 |
콘티넨탈 오토모티브 게엠베하 |
마이크로컴퓨터의 프로그램 실행 모니터링 방법
|
|
DE602004017726D1
(de)
|
2003-06-30 |
2008-12-24 |
Domantis Ltd |
Pegylierte Single-domain-antikörper (dAb)
|
|
EP1656128A4
(en)
|
2003-08-12 |
2007-02-28 |
William M Yarbrough |
SINGLE ACNE TREATMENT AND METHOD OF USE
|
|
EP1512696A1
(en)
|
2003-08-14 |
2005-03-09 |
Diatos |
Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei
|
|
EP1737971B1
(en)
|
2004-01-20 |
2017-08-16 |
Merus N.V. |
Mixtures of binding proteins
|
|
EP1720908A2
(en)
|
2004-02-17 |
2006-11-15 |
Absalus, Inc. |
Super-humanized antibodies against respiratory syncytial virus
|
|
US7207410B2
(en)
|
2004-04-29 |
2007-04-24 |
Daimlerchrysler Corporation |
Apparatus and method for enhanced impact sensing
|
|
US7632924B2
(en)
|
2004-06-18 |
2009-12-15 |
Ambrx, Inc. |
Antigen-binding polypeptides and their uses
|
|
CA2572917C
(en)
|
2004-07-06 |
2012-04-03 |
Bioren Inc. |
Look-through mutagenesis for developing altered polypeptides with enhanced properties
|
|
US7180370B2
(en)
|
2004-09-01 |
2007-02-20 |
Micron Technology, Inc. |
CMOS amplifiers with frequency compensating capacitors
|
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
|
EP1793850A4
(en)
|
2004-09-21 |
2010-06-30 |
Medimmune Inc |
ANTIBODIES TO THE METHOD AND METHOD FOR THE PRODUCTION OF VACCINES AGAINST THE RESPIRATORY SYNCYTIAL VIRUS
|
|
WO2006040153A2
(en)
|
2004-10-13 |
2006-04-20 |
Ablynx N.V. |
Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease
|
|
TW200636064A
(en)
*
|
2004-10-28 |
2006-10-16 |
Centocor Inc |
Anti-respiratory syncytial virus antibodies, antigens and uses thereof
|
|
WO2006050166A2
(en)
|
2004-10-29 |
2006-05-11 |
Medimmune, Inc. |
Methods of preventing and treating rsv infections and related conditions
|
|
MX2007006593A
(es)
*
|
2004-12-02 |
2008-03-04 |
Domantis Ltd |
Anticuerpos de dominio simple anti-il 1r1 y sus usos terapeuticos.
|
|
CA2604032C
(en)
|
2005-04-06 |
2017-08-22 |
Ibc Pharmaceuticals, Inc. |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
|
|
JP4976376B2
(ja)
|
2005-04-08 |
2012-07-18 |
メディミューン，エルエルシー |
哺乳動物メタニューモウイルスに対する抗体
|
|
US8188223B2
(en)
|
2005-05-18 |
2012-05-29 |
Ablynx N.V. |
Serum albumin binding proteins
|
|
WO2008020079A1
(en)
|
2006-08-18 |
2008-02-21 |
Ablynx N.V. |
Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling
|
|
AU2007293614A1
(en)
|
2006-09-08 |
2008-03-13 |
Ablynx N.V. |
Serum albumin binding proteins with long half-lives
|
|
ATE536369T1
(de)
|
2006-10-11 |
2011-12-15 |
Ablynx Nv |
Im wesentlichen ph-wert-unabhängigerweise an serumproteine bindende aminosäuresequenzen, verbindungen, die diese enthalten, und deren verwendung
|
|
US20100034194A1
(en)
|
2006-10-11 |
2010-02-11 |
Siemens Communications Inc. |
Eliminating unreachable subscribers in voice-over-ip networks
|
|
CA2667466A1
(en)
|
2006-10-27 |
2008-05-02 |
Ablynx N.V. |
Intranasal delivery of polypeptides and proteins
|
|
US20080267949A1
(en)
|
2006-12-05 |
2008-10-30 |
Ablynx N.V. |
Peptides capable of binding to serum proteins
|
|
WO2008077945A2
(en)
|
2006-12-22 |
2008-07-03 |
Ablynx N.V. |
Anti-chemokine (ccl2, ccl3, ccl5, cxcl11, cxcl12) single-domain antibodies
|
|
AU2008270274B2
(en)
|
2007-07-03 |
2012-06-28 |
Ablynx N.V. |
Providing improved immunoglobulin sequences by mutating CDR and/or FR positions
|
|
EP2650311A3
(en)
|
2007-11-27 |
2014-06-04 |
Ablynx N.V. |
Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same
|
|
EP2096121A1
(en)
|
2008-02-29 |
2009-09-02 |
Institut Pasteur Of Shanghai |
Antiviral peptides comprising lipid attachment signals and methods of use
|
|
LT2285408T
(lt)
|
2008-06-05 |
2019-01-25 |
Ablynx N.V. |
Aminorūgščių sekos, nukreiptos prieš viruso apvalkalo baltymus, ir tokias sekas turintys polipeptidai, skirti virusinių ligų gydymui
|
|
PT2387583T
(pt)
|
2009-01-14 |
2018-12-24 |
Ablynx Nv |
Administração pulmonar de domínios de variável única de imunoglobulina e construtos dos mesmos
|
|
AU2010243551B2
(en)
|
2009-04-30 |
2015-03-26 |
Ablynx Nv |
Method for the production of domain antibodies
|
|
PT2438087T
(pt)
|
2009-06-05 |
2017-08-04 |
Ablynx Nv |
Construções de nanobody trivalentes de vírus sincicial respiratório humano (hrsv) para a prevenção e/ou tratamento de infeções do trato respiratório
|
|
WO2011064382A1
(en)
|
2009-11-30 |
2011-06-03 |
Ablynx N.V. |
Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
|