JP2012526561A5 - - Google Patents
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- JP2012526561A5 JP2012526561A5 JP2012511059A JP2012511059A JP2012526561A5 JP 2012526561 A5 JP2012526561 A5 JP 2012526561A5 JP 2012511059 A JP2012511059 A JP 2012511059A JP 2012511059 A JP2012511059 A JP 2012511059A JP 2012526561 A5 JP2012526561 A5 JP 2012526561A5
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- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 claims 62
- 244000005700 microbiome Species 0.000 claims 46
- 108090000623 proteins and genes Proteins 0.000 claims 46
- 230000037361 pathway Effects 0.000 claims 31
- 102000004190 Enzymes Human genes 0.000 claims 19
- 108090000790 Enzymes Proteins 0.000 claims 19
- 108090000604 Hydrolases Proteins 0.000 claims 17
- 102000004157 Hydrolases Human genes 0.000 claims 17
- 101100297400 Rhizobium meliloti (strain 1021) phaAB gene Proteins 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 14
- 150000007523 nucleic acids Chemical class 0.000 claims 14
- 102000039446 nucleic acids Human genes 0.000 claims 14
- 101150110984 phaB gene Proteins 0.000 claims 14
- 108090000489 Carboxy-Lyases Proteins 0.000 claims 11
- 102000003960 Ligases Human genes 0.000 claims 11
- 108090000364 Ligases Proteins 0.000 claims 11
- 108090000472 Phosphoenolpyruvate carboxykinase (ATP) Proteins 0.000 claims 11
- 102000004357 Transferases Human genes 0.000 claims 11
- 108090000992 Transferases Proteins 0.000 claims 11
- 150000007970 thio esters Chemical class 0.000 claims 11
- 101100280476 Streptococcus pneumoniae (strain ATCC BAA-255 / R6) fabM gene Proteins 0.000 claims 9
- 101150069125 fadB gene Proteins 0.000 claims 9
- 101150090310 pimF gene Proteins 0.000 claims 9
- 101100350708 Escherichia coli (strain K12) paaF gene Proteins 0.000 claims 8
- 101100350716 Pseudomonas putida paaK gene Proteins 0.000 claims 8
- 101150088738 pckA gene Proteins 0.000 claims 8
- 101150067708 pckG gene Proteins 0.000 claims 8
- 101100463818 Pseudomonas oleovorans phaC1 gene Proteins 0.000 claims 7
- 101150046540 phaA gene Proteins 0.000 claims 7
- 108030005660 3-hydroxybutyryl-CoA dehydratases Proteins 0.000 claims 6
- QNVIXZIHJGSYSU-UHFFFAOYSA-N 6-oxocyclohexene-1-carboxylic acid Chemical compound OC(=O)C1=CCCCC1=O QNVIXZIHJGSYSU-UHFFFAOYSA-N 0.000 claims 6
- 108700016155 Acyl transferases Proteins 0.000 claims 6
- 102000057234 Acyl transferases Human genes 0.000 claims 6
- 108010015451 Glutaryl-CoA Dehydrogenase Proteins 0.000 claims 6
- 102100028603 Glutaryl-CoA dehydrogenase, mitochondrial Human genes 0.000 claims 6
- 108090001042 Hydro-Lyases Proteins 0.000 claims 6
- 102000004867 Hydro-Lyases Human genes 0.000 claims 6
- 102000004316 Oxidoreductases Human genes 0.000 claims 6
- 108090000854 Oxidoreductases Proteins 0.000 claims 6
- SYKWLIJQEHRDNH-CKRMAKSASA-N glutaryl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCCC(O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 SYKWLIJQEHRDNH-CKRMAKSASA-N 0.000 claims 6
- -1 syn_02642 Proteins 0.000 claims 6
- POROIMOHDIEBBO-UHFFFAOYSA-N 2-oxocyclohexanecarboxylic acid Chemical compound OC(=O)C1CCCCC1=O POROIMOHDIEBBO-UHFFFAOYSA-N 0.000 claims 5
- VGEBXBQECGWCRH-JXUSAFQPSA-N 3-hydroxypimeloyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)CCCC(O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 VGEBXBQECGWCRH-JXUSAFQPSA-N 0.000 claims 5
- 108030004902 Cyclohexanone dehydrogenases Proteins 0.000 claims 5
- 101100243777 Dictyostelium discoideum phbB gene Proteins 0.000 claims 5
- 101150019065 HBD gene Proteins 0.000 claims 5
- 108091000039 acetoacetyl-CoA reductase Proteins 0.000 claims 5
- LYCRXMTYUZDUGA-UYRKPTJQSA-N pimeloyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCCCCC(O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 LYCRXMTYUZDUGA-UYRKPTJQSA-N 0.000 claims 5
- 101150007867 rbfox2 gene Proteins 0.000 claims 5
- 102100039358 3-hydroxyacyl-CoA dehydrogenase type-2 Human genes 0.000 claims 4
- 108030006717 3-hydroxypimeloyl-CoA dehydrogenases Proteins 0.000 claims 4
- KJXFOFKTZDJLMQ-UYRKPTJQSA-N 3-oxopimeloyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(=O)CCCC(O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 KJXFOFKTZDJLMQ-UYRKPTJQSA-N 0.000 claims 4
- 101100228725 Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) gctA gene Proteins 0.000 claims 4
- 101100228726 Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) gctB gene Proteins 0.000 claims 4
- 101150097247 CRT1 gene Proteins 0.000 claims 4
- 101100385314 Clostridioides difficile crt gene Proteins 0.000 claims 4
- 101100385572 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) ctfA gene Proteins 0.000 claims 4
- 101100385573 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) ctfB gene Proteins 0.000 claims 4
- 101100322572 Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) adc gene Proteins 0.000 claims 4
- 101100322573 Clostridium botulinum (strain Eklund 17B / Type B) adc gene Proteins 0.000 claims 4
- 101000636215 Crotalus durissus terrificus Crotamine Proteins 0.000 claims 4
- 102100023044 Cytosolic acyl coenzyme A thioester hydrolase Human genes 0.000 claims 4
- 101710152190 Cytosolic acyl coenzyme A thioester hydrolase Proteins 0.000 claims 4
- 101100342473 Drosophila melanogaster Raf gene Proteins 0.000 claims 4
- 101100447155 Escherichia coli (strain K12) fre gene Proteins 0.000 claims 4
- 101100350700 Escherichia coli (strain K12) paaB gene Proteins 0.000 claims 4
- 101100350709 Escherichia coli (strain K12) paaG gene Proteins 0.000 claims 4
- 101100082074 Escherichia coli (strain K12) paaZ gene Proteins 0.000 claims 4
- 101001035740 Homo sapiens 3-hydroxyacyl-CoA dehydrogenase type-2 Proteins 0.000 claims 4
- 101000734572 Homo sapiens Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Proteins 0.000 claims 4
- 101000716763 Homo sapiens Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial Proteins 0.000 claims 4
- 101000716795 Homo sapiens Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial Proteins 0.000 claims 4
- 101100236497 Klebsiella aerogenes maoC gene Proteins 0.000 claims 4
- 102100034796 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Human genes 0.000 claims 4
- 101100296562 Pseudomonas putida pcaI gene Proteins 0.000 claims 4
- 101100332697 Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) fadB1 gene Proteins 0.000 claims 4
- 101100352050 Serratia liquefaciens phlB gene Proteins 0.000 claims 4
- 101100269618 Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) aliA gene Proteins 0.000 claims 4
- 102100020868 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial Human genes 0.000 claims 4
- 102100020869 Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial Human genes 0.000 claims 4
- 101150006589 adc gene Proteins 0.000 claims 4
- 101150063145 atoA gene Proteins 0.000 claims 4
- 101150008413 atoD gene Proteins 0.000 claims 4
- 101150056596 azin2 gene Proteins 0.000 claims 4
- 101150016301 bioW gene Proteins 0.000 claims 4
- 101150088413 catI gene Proteins 0.000 claims 4
- 101150031590 catJ gene Proteins 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 101150004992 fadA gene Proteins 0.000 claims 4
- 101150027774 fadI gene Proteins 0.000 claims 4
- 101150092019 fadJ gene Proteins 0.000 claims 4
- 101150115959 fadR gene Proteins 0.000 claims 4
- 101150037784 paaA gene Proteins 0.000 claims 4
- 101150004383 pcaJ gene Proteins 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 101150031436 sucD gene Proteins 0.000 claims 4
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 4
- 101100282377 Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) gcdA gene Proteins 0.000 claims 3
- 101100282378 Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) gcdB gene Proteins 0.000 claims 3
- 101100282379 Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) gcdC gene Proteins 0.000 claims 3
- 101100282380 Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) gcdD gene Proteins 0.000 claims 3
- 101100273316 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) catF gene Proteins 0.000 claims 3
- 101001041037 Arabidopsis thaliana Lariat debranching enzyme Proteins 0.000 claims 3
- 102100021973 Carbonyl reductase [NADPH] 1 Human genes 0.000 claims 3
- 101100326160 Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) bktB gene Proteins 0.000 claims 3
- 101150051269 ERG10 gene Proteins 0.000 claims 3
- 101000896985 Homo sapiens Carbonyl reductase [NADPH] 1 Proteins 0.000 claims 3
- 101100445407 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) erg10B gene Proteins 0.000 claims 3
- 101100296558 Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13) pcaF gene Proteins 0.000 claims 3
- 101100494806 Pseudomonas syringae pv. syringae katB gene Proteins 0.000 claims 3
- 101100058745 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) IRC24 gene Proteins 0.000 claims 3
- 101100160336 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) YML131W gene Proteins 0.000 claims 3
- 101150006429 atoB gene Proteins 0.000 claims 3
- FWFSEYBSWVRWGL-UHFFFAOYSA-N cyclohex-2-enone Chemical compound O=C1CCCC=C1 FWFSEYBSWVRWGL-UHFFFAOYSA-N 0.000 claims 3
- 101150082586 fadH gene Proteins 0.000 claims 3
- 101150033034 gcvA gene Proteins 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 101150091724 mgtA gene Proteins 0.000 claims 3
- 101150023648 pcaF gene Proteins 0.000 claims 3
- 101150100761 pimB gene Proteins 0.000 claims 3
- 101150096860 thlA gene Proteins 0.000 claims 3
- 108030005094 3-hydroxycyclohexanone dehydrogenases Proteins 0.000 claims 2
- IYNRULSFFKEOLT-UHFFFAOYSA-N 3-oxopimelic acid Chemical compound OC(=O)CCCC(=O)CC(O)=O IYNRULSFFKEOLT-UHFFFAOYSA-N 0.000 claims 2
- 101100235000 Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) lctB gene Proteins 0.000 claims 2
- 101100235003 Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) lctC gene Proteins 0.000 claims 2
- 101100043145 Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1) acd gene Proteins 0.000 claims 2
- 108030006973 Cyclohexane-1,2-diol dehydrogenases Proteins 0.000 claims 2
- 102100022768 D-beta-hydroxybutyrate dehydrogenase, mitochondrial Human genes 0.000 claims 2
- 101150110799 ETFA gene Proteins 0.000 claims 2
- 101150046595 ETFB gene Proteins 0.000 claims 2
- 101710198510 Enoyl-[acyl-carrier-protein] reductase [NADH] Proteins 0.000 claims 2
- 101000903373 Homo sapiens D-beta-hydroxybutyrate dehydrogenase, mitochondrial Proteins 0.000 claims 2
- 101000836268 Homo sapiens U4/U6.U5 tri-snRNP-associated protein 1 Proteins 0.000 claims 2
- 101100533888 Hypocrea jecorina (strain QM6a) sor4 gene Proteins 0.000 claims 2
- 108030000285 Pimeloyl-CoA dehydrogenases Proteins 0.000 claims 2
- 101100121588 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GCY1 gene Proteins 0.000 claims 2
- 101100069420 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GRE3 gene Proteins 0.000 claims 2
- 101100053441 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) YPR1 gene Proteins 0.000 claims 2
- 101710177013 Trans-2-enoyl-CoA reductase [NADH] Proteins 0.000 claims 2
- 102100027244 U4/U6.U5 tri-snRNP-associated protein 1 Human genes 0.000 claims 2
- 101710185376 Very-long-chain enoyl-CoA reductase Proteins 0.000 claims 2
- 101150108612 aroQ gene Proteins 0.000 claims 2
- 101150091634 bcd gene Proteins 0.000 claims 2
- 101150019823 chnA gene Proteins 0.000 claims 2
- PFURGBBHAOXLIO-WDSKDSINSA-N cyclohexane-1,2-diol Chemical compound O[C@H]1CCCC[C@@H]1O PFURGBBHAOXLIO-WDSKDSINSA-N 0.000 claims 2
- 101150043763 pimC gene Proteins 0.000 claims 2
- 108010092687 2-ketocyclohexanecarboxyl-coenzyme A hydrolase Proteins 0.000 claims 1
- BGLNPJARTQOCKR-OXXAVVHVSA-N 2-oxocyclohexane-1-carbonyl-CoA Chemical compound O=C([C@H](O)C(C)(COP(O)(=O)OP(O)(=O)OC[C@@H]1[C@H]([C@@H](O)[C@@H](O1)N1C2=NC=NC(N)=C2N=C1)OP(O)(O)=O)C)NCCC(=O)NCCSC(=O)C1CCCCC1=O BGLNPJARTQOCKR-OXXAVVHVSA-N 0.000 claims 1
- 102000052553 3-Hydroxyacyl CoA Dehydrogenase Human genes 0.000 claims 1
- 108700020831 3-Hydroxyacyl-CoA Dehydrogenase Proteins 0.000 claims 1
- MGTZCLMLSSAXLD-UHFFFAOYSA-N 5-oxohexanoic acid Chemical compound CC(=O)CCCC(O)=O MGTZCLMLSSAXLD-UHFFFAOYSA-N 0.000 claims 1
- PNPPVRALIYXJBW-UHFFFAOYSA-N 6-oxohexanoic acid Chemical compound OC(=O)CCCCC=O PNPPVRALIYXJBW-UHFFFAOYSA-N 0.000 claims 1
- 101100277683 Citrobacter freundii dhaB gene Proteins 0.000 claims 1
- 101100135918 Citrobacter freundii pduG gene Proteins 0.000 claims 1
- 101100506756 Glycine max HIDH gene Proteins 0.000 claims 1
- 101100506757 Glycyrrhiza echinata HIDM gene Proteins 0.000 claims 1
- 241000155250 Iole Species 0.000 claims 1
- 101100498822 Klebsiella oxytoca (strain ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686) ddrA gene Proteins 0.000 claims 1
- 101100498826 Klebsiella oxytoca (strain ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686) ddrB gene Proteins 0.000 claims 1
- 229920002292 Nylon 6 Polymers 0.000 claims 1
- 229920002302 Nylon 6,6 Polymers 0.000 claims 1
- 102000001253 Protein Kinase Human genes 0.000 claims 1
- 101100109922 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) aroQ1 gene Proteins 0.000 claims 1
- 101100505872 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) xcpT gene Proteins 0.000 claims 1
- 101100016013 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) xcpU gene Proteins 0.000 claims 1
- 101100016023 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) xcpV gene Proteins 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 101100135913 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) pduC gene Proteins 0.000 claims 1
- 101100135914 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) pduD gene Proteins 0.000 claims 1
- 101100135915 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) pduE gene Proteins 0.000 claims 1
- OJFDKHTZOUZBOS-CITAKDKDSA-N acetoacetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 OJFDKHTZOUZBOS-CITAKDKDSA-N 0.000 claims 1
- 101150102858 aroD gene Proteins 0.000 claims 1
- 101150040872 aroE gene Proteins 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 101150106256 bamA gene Proteins 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 101150011756 ddrA gene Proteins 0.000 claims 1
- 101150073964 ddrB gene Proteins 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 101150043028 ilvD gene Proteins 0.000 claims 1
- 101150105723 ilvD1 gene Proteins 0.000 claims 1
- 101150069525 iolE gene Proteins 0.000 claims 1
- 101150095079 menB gene Proteins 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- DDAKTXCYCCRJKJ-UHFFFAOYSA-N methyl 4-hydroxy-5-iodo-2,3-dimethoxy-6-methylbenzoate Chemical compound COC(=O)C1=C(C)C(I)=C(O)C(OC)=C1OC DDAKTXCYCCRJKJ-UHFFFAOYSA-N 0.000 claims 1
- 101150097419 pduH gene Proteins 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17879109P | 2009-05-15 | 2009-05-15 | |
| US61/178,791 | 2009-05-15 | ||
| PCT/US2010/035015 WO2010132845A1 (en) | 2009-05-15 | 2010-05-14 | Organisms for the production of cyclohexanone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012526561A JP2012526561A (ja) | 2012-11-01 |
| JP2012526561A5 true JP2012526561A5 (enExample) | 2013-06-27 |
Family
ID=43085363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012511059A Pending JP2012526561A (ja) | 2009-05-15 | 2010-05-14 | シクロヘキサノンの産生のための生物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8663957B2 (enExample) |
| EP (1) | EP2429587A4 (enExample) |
| JP (1) | JP2012526561A (enExample) |
| KR (1) | KR20120036851A (enExample) |
| AU (1) | AU2010248831A1 (enExample) |
| BR (1) | BRPI1012877A2 (enExample) |
| WO (1) | WO2010132845A1 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8129154B2 (en) | 2008-06-17 | 2012-03-06 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
| US20100184173A1 (en) * | 2008-11-14 | 2010-07-22 | Genomatica, Inc. | Microorganisms for the production of methyl ethyl ketone and 2-butanol |
| KR20110097951A (ko) | 2008-12-16 | 2011-08-31 | 게노마티카 인코포레이티드 | 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법 |
| EP2429587A4 (en) * | 2009-05-15 | 2014-10-08 | Genomatica Inc | ORGANISMS FOR THE PREPARATION OF CYCLOHEXANONE |
| JP2012529889A (ja) * | 2009-06-10 | 2012-11-29 | ゲノマチカ， インク． | Ｍｅｋ及び２−ブタノールの炭素効率のよい生合成のための微生物及び方法 |
| CN109136161A (zh) | 2009-12-10 | 2019-01-04 | 基因组股份公司 | 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体 |
| CA2787314A1 (en) * | 2010-01-29 | 2011-08-04 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of p-toluate and terephthalate |
| RU2012138943A (ru) * | 2010-02-12 | 2014-03-20 | Джево, Инк. | Дрожжевые микроорганизмы с пониженным накоплением побочных продуктов для улучшенного производства топлив, химикатов и аминокислот |
| US8637286B2 (en) * | 2010-02-23 | 2014-01-28 | Genomatica, Inc. | Methods for increasing product yields |
| US9334508B2 (en) | 2011-06-17 | 2016-05-10 | Invista North America S.A.R.L. | Methods of producing carboxylic acids |
| WO2013003432A1 (en) * | 2011-06-29 | 2013-01-03 | Genomatica, Inc. | Microorganisms for producing succinate and methods related thereto |
| BR112013033672A2 (pt) | 2011-06-30 | 2017-03-14 | Invista Tech Sarl | método para converter um composto, cultura substancialmente pura de células hospedeiras e cèlula isolada |
| CN103998600A (zh) * | 2011-09-07 | 2014-08-20 | 威廉马什莱斯大学 | 通过反向脂肪酸氧化的官能化羧酸和醇 |
| US8940509B2 (en) | 2011-11-02 | 2015-01-27 | Genomatica, Inc. | Microorganisms and methods for the production of caprolactone |
| US9102960B2 (en) | 2011-12-16 | 2015-08-11 | Invista North America S.á.r.l. | Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage |
| US9102958B2 (en) | 2011-12-16 | 2015-08-11 | Invista North America S.á.r.l. | Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage |
| EP2794891A2 (en) | 2011-12-20 | 2014-10-29 | Scientist of Fortune S.A. | Production of 1,3-dienes by enzymatic conversion of 3-hydroxyalk-4-enoates and/or 3-phosphonoxyalk-4-enoates |
| WO2014093847A2 (en) | 2012-12-14 | 2014-06-19 | Invista North America S.A.R.L. | METHODS OF PRODUCING 7-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE |
| EP2938732A1 (en) | 2012-12-31 | 2015-11-04 | Invista Technologies S.à.r.l. | Methods of producing 7-carbon chemicals from long chain fatty acids via oxidative cleavage |
| EP2938736A2 (en) | 2012-12-31 | 2015-11-04 | Invista Technologies S.A R.L. | Methods of producing 7-carbon chemicals via c1 carbon chain elongation associated with coenzyme b synthesis |
| US9738911B2 (en) | 2012-12-31 | 2017-08-22 | Invista North America S.A.R.L. | Methods of producing 7-carbon chemicals via pyruvate and succinate semialdehyde aldol condensation |
| CN105189770A (zh) | 2012-12-31 | 2015-12-23 | 英威达技术有限责任公司 | 通过与环己烷羧酸合成相关的碳链延伸生产7碳化学物的方法 |
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