JP2012525156A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012525156A5 JP2012525156A5 JP2012508799A JP2012508799A JP2012525156A5 JP 2012525156 A5 JP2012525156 A5 JP 2012525156A5 JP 2012508799 A JP2012508799 A JP 2012508799A JP 2012508799 A JP2012508799 A JP 2012508799A JP 2012525156 A5 JP2012525156 A5 JP 2012525156A5
- Authority
- JP
- Japan
- Prior art keywords
- coa
- encoded
- group
- reductase
- genes selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000854 Oxidoreductases Proteins 0.000 claims 53
- 108090000623 proteins and genes Proteins 0.000 claims 41
- 244000005700 microbiome Species 0.000 claims 40
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims 32
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims 28
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 23
- -1 adh-A Proteins 0.000 claims 21
- 230000015572 biosynthetic process Effects 0.000 claims 20
- 101100297400 Rhizobium meliloti (strain 1021) phaAB gene Proteins 0.000 claims 16
- 230000037361 pathway Effects 0.000 claims 15
- ZTQSAGDEMFDKMZ-UHFFFAOYSA-N Butyraldehyde Chemical compound CCCC=O ZTQSAGDEMFDKMZ-UHFFFAOYSA-N 0.000 claims 14
- 229920000642 polymer Polymers 0.000 claims 14
- 108010035023 4-hydroxybutyryl-CoA dehydratase Proteins 0.000 claims 13
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 12
- 102000004190 Enzymes Human genes 0.000 claims 12
- 108090000790 Enzymes Proteins 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 12
- KFWWCMJSYSSPSK-PAXLJYGASA-N crotonoyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)/C=C/C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 KFWWCMJSYSSPSK-PAXLJYGASA-N 0.000 claims 12
- 101150110984 phaB gene Proteins 0.000 claims 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 10
- AMIMRNSIRUDHCM-UHFFFAOYSA-N Isopropylaldehyde Chemical compound CC(C)C=O AMIMRNSIRUDHCM-UHFFFAOYSA-N 0.000 claims 10
- ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 claims 10
- 150000001299 aldehydes Chemical class 0.000 claims 10
- CRFNGMNYKDXRTN-CITAKDKDSA-N butyryl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCC)O[C@H]1N1C2=NC=NC(N)=C2N=C1 CRFNGMNYKDXRTN-CITAKDKDSA-N 0.000 claims 10
- AEWHYWSPVRZHCT-NDZSKPAWSA-N isobutyryl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C(C)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 AEWHYWSPVRZHCT-NDZSKPAWSA-N 0.000 claims 10
- 101100280476 Streptococcus pneumoniae (strain ATCC BAA-255 / R6) fabM gene Proteins 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 9
- 150000007523 nucleic acids Chemical class 0.000 claims 9
- 102000039446 nucleic acids Human genes 0.000 claims 9
- 101100338533 Clostridium aminobutyricum abfD gene Proteins 0.000 claims 8
- 101150056881 mcr gene Proteins 0.000 claims 8
- 102100022523 Acetoacetyl-CoA synthetase Human genes 0.000 claims 7
- 101150097247 CRT1 gene Proteins 0.000 claims 7
- 101000636215 Crotalus durissus terrificus Crotamine Proteins 0.000 claims 7
- 101100350700 Escherichia coli (strain K12) paaB gene Proteins 0.000 claims 7
- 101100350708 Escherichia coli (strain K12) paaF gene Proteins 0.000 claims 7
- 101100082074 Escherichia coli (strain K12) paaZ gene Proteins 0.000 claims 7
- 101100236497 Klebsiella aerogenes maoC gene Proteins 0.000 claims 7
- 101100463818 Pseudomonas oleovorans phaC1 gene Proteins 0.000 claims 7
- 101100350716 Pseudomonas putida paaK gene Proteins 0.000 claims 7
- 238000004519 manufacturing process Methods 0.000 claims 7
- 101150037784 paaA gene Proteins 0.000 claims 7
- 101150046540 phaA gene Proteins 0.000 claims 7
- HGBOYTHUEUWSSQ-UHFFFAOYSA-N valeric aldehyde Natural products CCCCC=O HGBOYTHUEUWSSQ-UHFFFAOYSA-N 0.000 claims 7
- 101100235000 Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) lctB gene Proteins 0.000 claims 6
- 101100235003 Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) lctC gene Proteins 0.000 claims 6
- 101100043145 Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1) acd gene Proteins 0.000 claims 6
- 101100099093 Drosophila melanogaster term gene Proteins 0.000 claims 6
- 101150110799 ETFA gene Proteins 0.000 claims 6
- 101150046595 ETFB gene Proteins 0.000 claims 6
- 101100350709 Escherichia coli (strain K12) paaG gene Proteins 0.000 claims 6
- 108090001042 Hydro-Lyases Proteins 0.000 claims 6
- 102000004867 Hydro-Lyases Human genes 0.000 claims 6
- 101100278182 Mus musculus Dnd1 gene Proteins 0.000 claims 6
- 101100332697 Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) fadB1 gene Proteins 0.000 claims 6
- 108091022873 acetoacetate decarboxylase Proteins 0.000 claims 6
- 101150091634 bcd gene Proteins 0.000 claims 6
- 101150031436 sucD gene Proteins 0.000 claims 6
- WWEOGFZEFHPUAM-MIZDRFBCSA-N 3-hydroxy-2-methylpropanoyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C(CO)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 WWEOGFZEFHPUAM-MIZDRFBCSA-N 0.000 claims 5
- BAMBWCGEVIAQBF-CITAKDKDSA-N 4-hydroxybutyryl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCCO)O[C@H]1N1C2=NC=NC(N)=C2N=C1 BAMBWCGEVIAQBF-CITAKDKDSA-N 0.000 claims 5
- 101100162204 Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) aflH gene Proteins 0.000 claims 5
- 101100174521 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) fumC2 gene Proteins 0.000 claims 5
- 101100335628 Dictyostelium discoideum fumH gene Proteins 0.000 claims 5
- 101100174518 Escherichia coli (strain K12) fumB gene Proteins 0.000 claims 5
- 108030005217 Isobutyryl-CoA mutases Proteins 0.000 claims 5
- 101100120826 Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) fumC gene Proteins 0.000 claims 5
- 101100443340 Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) dmdB gene Proteins 0.000 claims 5
- 108090000992 Transferases Proteins 0.000 claims 5
- 102000004357 Transferases Human genes 0.000 claims 5
- 108010022074 acetoacetyl-CoA hydrolase Proteins 0.000 claims 5
- 108010012842 acetoacetyl-CoA synthetase Proteins 0.000 claims 5
- 101150024743 adhA gene Proteins 0.000 claims 5
- 101150012368 dmdA gene Proteins 0.000 claims 5
- 101150004244 fumA gene Proteins 0.000 claims 5
- 101150028420 fumC gene Proteins 0.000 claims 5
- 239000002609 medium Substances 0.000 claims 5
- 108010055682 3-hydroxybutyryl-CoA dehydrogenase Proteins 0.000 claims 4
- 102100034044 All-trans-retinol dehydrogenase [NAD(+)] ADH1B Human genes 0.000 claims 4
- 101710193111 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Proteins 0.000 claims 4
- 101100098786 Bacillus subtilis (strain 168) tapA gene Proteins 0.000 claims 4
- 101100335626 Caenorhabditis elegans fum-1 gene Proteins 0.000 claims 4
- 101100108227 Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) adhI gene Proteins 0.000 claims 4
- 101100269671 Dictyostelium discoideum alrA gene Proteins 0.000 claims 4
- 101100072012 Dictyostelium discoideum icmt-2 gene Proteins 0.000 claims 4
- 108010023922 Enoyl-CoA hydratase Proteins 0.000 claims 4
- 102000011426 Enoyl-CoA hydratase Human genes 0.000 claims 4
- 101100108562 Escherichia coli (strain K12) aldA gene Proteins 0.000 claims 4
- 101100321116 Escherichia coli (strain K12) yqhD gene Proteins 0.000 claims 4
- 102100039894 Hemoglobin subunit delta Human genes 0.000 claims 4
- 101100456321 Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) Msed_0709 gene Proteins 0.000 claims 4
- 101100054327 Mus musculus Abcd1 gene Proteins 0.000 claims 4
- 101100269700 Mycolicibacterium smegmatis alr gene Proteins 0.000 claims 4
- 101150014383 adhE gene Proteins 0.000 claims 4
- 101150049512 ald gene Proteins 0.000 claims 4
- 101150008745 bphG gene Proteins 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 3
- 238000006243 chemical reaction Methods 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 101150069125 fadB gene Proteins 0.000 claims 3
- 101150092019 fadJ gene Proteins 0.000 claims 3
- 239000004922 lacquer Substances 0.000 claims 3
- NPALUEYCDZWBOV-NDZSKPAWSA-N methacrylyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C(=C)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 NPALUEYCDZWBOV-NDZSKPAWSA-N 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 239000002904 solvent Substances 0.000 claims 3
- 241000894007 species Species 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 102100039358 3-hydroxyacyl-CoA dehydrogenase type-2 Human genes 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 2
- SOGAXMICEFXMKE-UHFFFAOYSA-N Butylmethacrylate Chemical compound CCCCOC(=O)C(C)=C SOGAXMICEFXMKE-UHFFFAOYSA-N 0.000 claims 2
- 101100110009 Caenorhabditis elegans asd-2 gene Proteins 0.000 claims 2
- 101100183207 Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) mcm gene Proteins 0.000 claims 2
- 101100385572 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) ctfA gene Proteins 0.000 claims 2
- 101100385573 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) ctfB gene Proteins 0.000 claims 2
- 101100243777 Dictyostelium discoideum phbB gene Proteins 0.000 claims 2
- 241000233866 Fungi Species 0.000 claims 2
- 101150019065 HBD gene Proteins 0.000 claims 2
- 101100155953 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) uvrD gene Proteins 0.000 claims 2
- 101001035740 Homo sapiens 3-hydroxyacyl-CoA dehydrogenase type-2 Proteins 0.000 claims 2
- 101000678027 Homo sapiens Acetoacetyl-CoA synthetase Proteins 0.000 claims 2
- 101100078860 Porphyromonas gingivalis (strain ATCC BAA-308 / W83) mutA gene Proteins 0.000 claims 2
- 101100078866 Porphyromonas gingivalis (strain ATCC BAA-308 / W83) mutB gene Proteins 0.000 claims 2
- 101150088541 SCPA gene Proteins 0.000 claims 2
- 101100132330 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) mutY gene Proteins 0.000 claims 2
- 101100398785 Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R) ldhD gene Proteins 0.000 claims 2
- 101100510642 Streptococcus mutans lanA gene Proteins 0.000 claims 2
- 101100386830 Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) ddh gene Proteins 0.000 claims 2
- 101150023527 actA gene Proteins 0.000 claims 2
- 101150092394 argK gene Proteins 0.000 claims 2
- 101150063145 atoA gene Proteins 0.000 claims 2
- 101150008413 atoD gene Proteins 0.000 claims 2
- 239000002551 biofuel Substances 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 101150041588 eutE gene Proteins 0.000 claims 2
- 101150003440 hibch gene Proteins 0.000 claims 2
- 101150063051 hom gene Proteins 0.000 claims 2
- 101150026107 ldh1 gene Proteins 0.000 claims 2
- 101150041530 ldha gene Proteins 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 101150030499 lnt gene Proteins 0.000 claims 2
- 101150079289 mutA gene Proteins 0.000 claims 2
- 101150015240 mutB gene Proteins 0.000 claims 2
- 239000003973 paint Substances 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 101150033155 sspP gene Proteins 0.000 claims 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 2
- 101150087812 tesA gene Proteins 0.000 claims 2
- 101150014006 thrA gene Proteins 0.000 claims 2
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 claims 1
- 102100032282 26S proteasome non-ATPase regulatory subunit 14 Human genes 0.000 claims 1
- AXPZIVKEZRHGAS-UHFFFAOYSA-N 3-benzyl-5-[(2-nitrophenoxy)methyl]oxolan-2-one Chemical compound [O-][N+](=O)C1=CC=CC=C1OCC1OC(=O)C(CC=2C=CC=CC=2)C1 AXPZIVKEZRHGAS-UHFFFAOYSA-N 0.000 claims 1
- SJZRECIVHVDYJC-UHFFFAOYSA-M 4-hydroxybutyrate Chemical compound OCCCC([O-])=O SJZRECIVHVDYJC-UHFFFAOYSA-M 0.000 claims 1
- 101100228725 Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) gctA gene Proteins 0.000 claims 1
- 101100228726 Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) gctB gene Proteins 0.000 claims 1
- 101100171005 Amycolatopsis orientalis dpgB gene Proteins 0.000 claims 1
- 101100310362 Bacillus subtilis (strain 168) skfF gene Proteins 0.000 claims 1
- DKPFZGUDAPQIHT-UHFFFAOYSA-N Butyl acetate Natural products CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 claims 1
- 101150116295 CAT2 gene Proteins 0.000 claims 1
- 101100326920 Caenorhabditis elegans ctl-1 gene Proteins 0.000 claims 1
- 101100494773 Caenorhabditis elegans ctl-2 gene Proteins 0.000 claims 1
- 101100322572 Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) adc gene Proteins 0.000 claims 1
- 101100322573 Clostridium botulinum (strain Eklund 17B / Type B) adc gene Proteins 0.000 claims 1
- ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 claims 1
- 101100172445 Escherichia coli (strain K12) entH gene Proteins 0.000 claims 1
- 101100350711 Escherichia coli (strain K12) paaI gene Proteins 0.000 claims 1
- 101100545037 Escherichia coli (strain K12) yuaF gene Proteins 0.000 claims 1
- 101100112369 Fasciola hepatica Cat-1 gene Proteins 0.000 claims 1
- 101100342039 Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) kdpQ gene Proteins 0.000 claims 1
- 101000590281 Homo sapiens 26S proteasome non-ATPase regulatory subunit 14 Proteins 0.000 claims 1
- 101100242684 Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) panD1 gene Proteins 0.000 claims 1
- 101100005271 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) cat-1 gene Proteins 0.000 claims 1
- 101100028920 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) cfp gene Proteins 0.000 claims 1
- 101100126846 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) katG gene Proteins 0.000 claims 1
- 101100063536 Pseudomonas sp. (strain CF600) dmpH gene Proteins 0.000 claims 1
- 101150079502 acr1 gene Proteins 0.000 claims 1
- 101150006589 adc gene Proteins 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 101150056596 azin2 gene Proteins 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical group CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 210000003298 dental enamel Anatomy 0.000 claims 1
- 239000000645 desinfectant Substances 0.000 claims 1
- 239000003599 detergent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229920001971 elastomer Polymers 0.000 claims 1
- 235000011194 food seasoning agent Nutrition 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 claims 1
- 239000000976 ink Substances 0.000 claims 1
- GJRQTCIYDGXPES-UHFFFAOYSA-N iso-butyl acetate Natural products CC(C)COC(C)=O GJRQTCIYDGXPES-UHFFFAOYSA-N 0.000 claims 1
- FGKJLKRYENPLQH-UHFFFAOYSA-M isocaproate Chemical compound CC(C)CCC([O-])=O FGKJLKRYENPLQH-UHFFFAOYSA-M 0.000 claims 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 claims 1
- OQAGVSWESNCJJT-UHFFFAOYSA-N isovaleric acid methyl ester Natural products COC(=O)CC(C)C OQAGVSWESNCJJT-UHFFFAOYSA-N 0.000 claims 1
- 229920000126 latex Polymers 0.000 claims 1
- 239000004816 latex Substances 0.000 claims 1
- 101150033534 lysA gene Proteins 0.000 claims 1
- 101150080950 mdlC gene Proteins 0.000 claims 1
- 239000010705 motor oil Substances 0.000 claims 1
- 101150001292 padC gene Proteins 0.000 claims 1
- 101150076071 panD gene Proteins 0.000 claims 1
- 239000004033 plastic Substances 0.000 claims 1
- 239000005060 rubber Substances 0.000 claims 1
- 101150026728 tesB gene Proteins 0.000 claims 1
- 239000002966 varnish Substances 0.000 claims 1
- 101150102457 ybgC gene Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17448209P | 2009-04-30 | 2009-04-30 | |
| US61/174,482 | 2009-04-30 | ||
| PCT/US2010/033271 WO2010127303A1 (en) | 2009-04-30 | 2010-04-30 | Organisms for the production of isopropanol, n-butanol, and isobutanol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012525156A JP2012525156A (ja) | 2012-10-22 |
| JP2012525156A5 true JP2012525156A5 (enExample) | 2013-06-20 |
Family
ID=43032589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012508799A Pending JP2012525156A (ja) | 2009-04-30 | 2010-04-30 | イソプロパノール、ｎ−ブタノール、及びイソブタノールの産生のための微生物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8993285B2 (enExample) |
| EP (1) | EP2425006A4 (enExample) |
| JP (1) | JP2012525156A (enExample) |
| KR (1) | KR20120068763A (enExample) |
| AU (1) | AU2010242849A1 (enExample) |
| BR (1) | BRPI1013505A2 (enExample) |
| WO (1) | WO2010127303A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009155382A1 (en) | 2008-06-17 | 2009-12-23 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
| US20100184173A1 (en) * | 2008-11-14 | 2010-07-22 | Genomatica, Inc. | Microorganisms for the production of methyl ethyl ketone and 2-butanol |
| CA2746952A1 (en) | 2008-12-16 | 2010-06-24 | Genomatica, Inc. | Microorganisms and methods for conversion of syngas and other carbon sources to useful products |
| WO2010144746A2 (en) | 2009-06-10 | 2010-12-16 | Genomatica, Inc. | Microorganisms and methods for carbon-efficient biosynthesis of mek and 2-butanol |
| DE102009046623A1 (de) * | 2009-11-11 | 2011-05-12 | Evonik Röhm Gmbh | Verwendung eines zu einem MeaB-Protein homologen Proteins zur Erhöhung der enzymatischen Aktivität einer 3-Hydroxycarbonsäure-CoA-Mutase |
| CN102753698A (zh) | 2009-12-10 | 2012-10-24 | 基因组股份公司 | 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体 |
| US8637286B2 (en) | 2010-02-23 | 2014-01-28 | Genomatica, Inc. | Methods for increasing product yields |
| WO2012058566A1 (en) | 2010-10-29 | 2012-05-03 | Novozymes A/S | Polypeptides having succinyl-coa:aceto acetate transferase activity and polynucleotides encoding same |
| EP2678420A4 (en) * | 2011-02-25 | 2014-10-29 | Ohio State Innovation Foundation | AUTOTROPHE HYDROGEN BACTERIA AND USES THEREOF |
| WO2012177599A2 (en) * | 2011-06-22 | 2012-12-27 | Genomatica, Inc. | Microorganisms for producing n-propanol 1, 3-propanediol, 1,2-propanediol or glycerol and methods related thereto |
| WO2012177601A2 (en) * | 2011-06-22 | 2012-12-27 | Genomatica, Inc. | Microorganisms for producing isobutanol and methods related thereto |
| US9914947B2 (en) * | 2011-07-27 | 2018-03-13 | Alliance For Sustainable Energy, Llc | Biological production of organic compounds |
| AU2013230930B2 (en) * | 2012-03-06 | 2018-10-11 | Lygos, Inc. | Recombinant host cells for the production of malonate |
| KR102025458B1 (ko) | 2012-10-08 | 2019-09-25 | 칼리스타, 인코포레이티드 | 가스 공급 발효 시스템 |
| US9909150B2 (en) | 2012-11-05 | 2018-03-06 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,2-propanediol, n-propanol, 1,3-propanediol, or glycerol related thereto |
| US9469860B2 (en) * | 2013-01-18 | 2016-10-18 | Synata Bio, Inc. | Method for production of n-butanol from syngas using syntrophic co-cultures of anaerobic microorganisms |
| US20140206066A1 (en) * | 2013-01-18 | 2014-07-24 | Coskata, Inc. | Syntrophic co-culture of anaerobic microorganism for production of n-butanol from syngas |
| WO2014152434A2 (en) | 2013-03-15 | 2014-09-25 | Genomatica, Inc. | Microorganisms and methods for producing butadiene and related compounds by formate assimilation |
| PL3077501T3 (pl) | 2013-12-03 | 2022-01-31 | Genomatica, Inc. | Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa |
| ES2800606T3 (es) | 2013-12-27 | 2021-01-04 | Genomatica Inc | Métodos y organismos con mayores eficiencias del flujo de carbono |
| US20170298363A1 (en) | 2014-09-18 | 2017-10-19 | Genomatica, Inc | Non-natural microbial organisms with improved energetic efficiency |
| US20210079334A1 (en) | 2018-01-30 | 2021-03-18 | Genomatica, Inc. | Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
Family Cites Families (144)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3513209A (en) | 1968-08-19 | 1970-05-19 | Du Pont | Method of making 1,4-cyclohexadiene |
| US4076948A (en) | 1968-10-10 | 1978-02-28 | El Paso Products Company | Process for treatment of adipic acid mother liquor |
| GB1230276A (enExample) | 1968-12-09 | 1971-04-28 | ||
| US3965182A (en) | 1969-10-02 | 1976-06-22 | Ethyl Corporation | Preparation of aniline from phenol and ammonia |
| JPS506776Y1 (enExample) | 1969-12-27 | 1975-02-26 | ||
| JPS4831084B1 (enExample) | 1970-09-04 | 1973-09-26 | ||
| GB1344557A (en) | 1972-06-23 | 1974-01-23 | Mitsubishi Petrochemical Co | Process for preparing 1,4-butanediol |
| JPS5543759B2 (enExample) | 1972-06-28 | 1980-11-07 | ||
| DE2455617C3 (de) | 1974-11-23 | 1982-03-18 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von Butandiol und/oder Tetrahydrofuran über die Zwischenstufe des γ-Butyrolactons |
| DE2501499A1 (de) | 1975-01-16 | 1976-07-22 | Hoechst Ag | Verfahren zur herstellung von butandiol-(1.4) |
| US4190495A (en) | 1976-09-27 | 1980-02-26 | Research Corporation | Modified microorganisms and method of preparing and using same |
| US4301077A (en) | 1980-12-22 | 1981-11-17 | Standard Oil Company | Process for the manufacture of 1-4-butanediol and tetrahydrofuran |
| IT1190783B (it) | 1981-04-29 | 1988-02-24 | Davy Mckee Oil & Chem | Processo per l'idrogenolisi di esteri di acidi carbossilici |
| JPS6070088A (ja) * | 1983-09-26 | 1985-04-20 | Agency Of Ind Science & Technol | イソプロパノ−ルの製造方法 |
| JPS60114197A (ja) | 1983-11-25 | 1985-06-20 | Agency Of Ind Science & Technol | 微生物によるジカルボン酸の製造法 |
| US4871667A (en) | 1984-11-26 | 1989-10-03 | Agency Of Industrial Science & Technology | Process for preparing muconic acid |
| US4652685A (en) | 1985-11-15 | 1987-03-24 | General Electric Company | Hydrogenation of lactones to glycols |
| ES2036188T3 (es) | 1986-06-11 | 1993-05-16 | Michigan Biotechnology Institute | Un procedimiento para la produccion de acido succinico por fermentacion anaerobia. |
| US5168055A (en) | 1986-06-11 | 1992-12-01 | Rathin Datta | Fermentation and purification process for succinic acid |
| US5143834A (en) | 1986-06-11 | 1992-09-01 | Glassner David A | Process for the production and purification of succinic acid |
| US5182199A (en) | 1987-05-27 | 1993-01-26 | Hartley Brian S | Thermophilic ethanol production in a two-stage closed system |
| US5219757A (en) | 1988-04-27 | 1993-06-15 | Daicel Chemical Industries, Ltd. | Production of optically active 1,3-butanediol by asymmetric assimilation or reduction of 4-hydroxy-2-butanone |
| CA2062753C (en) | 1989-04-27 | 2005-04-26 | N. Robert Ward, Jr. | Precipitate test for microorganisms |
| JPH05506983A (ja) | 1990-03-09 | 1993-10-14 | バスフ ケイ アンド エフ コーポレイション | 天然長鎖アルコールの製造方法 |
| US5192673A (en) | 1990-04-30 | 1993-03-09 | Michigan Biotechnology Institute | Mutant strain of C. acetobutylicum and process for making butanol |
| US5079143A (en) | 1990-05-02 | 1992-01-07 | The Upjohn Company | Method of indentifying compounds useful as antiparasitic drugs |
| US5173429A (en) | 1990-11-09 | 1992-12-22 | The Board Of Trustees Of The University Of Arkansas | Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism |
| IL100572A (en) | 1991-01-03 | 1997-01-10 | Lepetit Spa | Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them |
| US5416020A (en) | 1992-09-29 | 1995-05-16 | Bio-Technical Resources | Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid |
| US6136577A (en) | 1992-10-30 | 2000-10-24 | Bioengineering Resources, Inc. | Biological production of ethanol from waste gases with Clostridium ljungdahlii |
| US5807722A (en) | 1992-10-30 | 1998-09-15 | Bioengineering Resources, Inc. | Biological production of acetic acid from waste gases with Clostridium ljungdahlii |
| FR2702492B1 (fr) | 1993-03-12 | 1995-05-24 | Rhone Poulenc Chimie | Procédé de production par fermentation d'acide itaconique. |
| US5487987A (en) | 1993-09-16 | 1996-01-30 | Purdue Research Foundation | Synthesis of adipic acid from biomass-derived carbon sources |
| US5521075A (en) | 1994-12-19 | 1996-05-28 | Michigan Biotechnology Institute | Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants |
| US5504004A (en) | 1994-12-20 | 1996-04-02 | Michigan Biotechnology Institute | Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms |
| US5700934A (en) | 1995-03-01 | 1997-12-23 | Dsm N.V. | Process for the preparation of epsilon-caprolactam and epsilon-caprolactam precursors |
| US5478952A (en) | 1995-03-03 | 1995-12-26 | E. I. Du Pont De Nemours And Company | Ru,Re/carbon catalyst for hydrogenation in aqueous solution |
| US5863782A (en) | 1995-04-19 | 1999-01-26 | Women's And Children's Hospital | Synthetic mammalian sulphamidase and genetic sequences encoding same |
| US5686276A (en) | 1995-05-12 | 1997-11-11 | E. I. Du Pont De Nemours And Company | Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism |
| FR2736927B1 (fr) | 1995-07-18 | 1997-10-17 | Rhone Poulenc Fibres & Polymer | Enzymes a activite amidase, outils genetiques et microorganismes hotes permettant leur obtention et procede d'hydrolyse mettant en oeuvre lesdites enzymes |
| US5573931A (en) | 1995-08-28 | 1996-11-12 | Michigan Biotechnology Institute | Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants |
| US5770435A (en) | 1995-11-02 | 1998-06-23 | University Of Chicago | Mutant E. coli strain with increased succinic acid production |
| US5869301A (en) | 1995-11-02 | 1999-02-09 | Lockhead Martin Energy Research Corporation | Method for the production of dicarboxylic acids |
| US5908924A (en) | 1996-02-27 | 1999-06-01 | Michigan State University | Cloning and expression of the gene encoding thermoanaerobacter ethanolicus 39E secondary-alcohol dehydrogenase and enzyme biochemical characterization |
| US5958745A (en) | 1996-03-13 | 1999-09-28 | Monsanto Company | Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants |
| KR100387301B1 (ko) | 1996-07-01 | 2003-06-12 | 바이오 엔지니어링 리소스 인코포레이티드 | 폐가스로부터의 생성물의 생물학적 제조방법 |
| KR100459818B1 (ko) | 1996-09-02 | 2004-12-03 | 이. 아이. 두퐁 드 느무르 앤드 컴퍼니 | ε-카프로락탐의 제조방법 |
| EP0977865A1 (en) | 1997-02-13 | 2000-02-09 | James Madison University | Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units |
| KR100516986B1 (ko) | 1997-02-19 | 2005-09-26 | 코닌클리즈케 디에스엠 엔.브이. | 6-아미노카프론산 유도체를 과열 수증기와 접촉시킴으로써 촉매 없이 카프로락탐을 제조하는 방법 |
| US6274790B1 (en) | 1997-04-14 | 2001-08-14 | The University Of British Columbia | Nucleic acids encoding a plant enzyme involved in very long chain fatty acid synthesis |
| KR19990013007A (ko) | 1997-07-31 | 1999-02-25 | 박원훈 | 형질전환된 대장균 ｓｓ373(ｋｃｔｃ 8818ｐ)과 이를 이용한숙신산의 생산방법 |
| JPH11103863A (ja) | 1997-10-08 | 1999-04-20 | Nippon Shokubai Co Ltd | マレイン酸異性化酵素遺伝子 |
| US6280986B1 (en) | 1997-12-01 | 2001-08-28 | The United States Of America As Represented By The Secretary Of Agriculture | Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities |
| MY121380A (en) | 1998-04-13 | 2006-01-28 | Univ Georgia | Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells |
| US20030087381A1 (en) | 1998-04-13 | 2003-05-08 | University Of Georgia Research Foundation, Inc. | Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals |
| US6159738A (en) | 1998-04-28 | 2000-12-12 | University Of Chicago | Method for construction of bacterial strains with increased succinic acid production |
| US6432686B1 (en) | 1998-05-12 | 2002-08-13 | E. I. Du Pont De Nemours And Company | Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport |
| US6444784B1 (en) | 1998-05-29 | 2002-09-03 | Exxonmobil Research & Engineering Company | Wax crystal modifiers (LAW657) |
| DE19856136C2 (de) | 1998-12-04 | 2002-10-24 | Pasteur Institut | Verfahren und Vorrichtung zur Selektion beschleunigter Proliferation lebender Zellen in Suspension |
| AU3482200A (en) | 1999-02-02 | 2000-08-25 | Bernhard Palsson | Methods for identifying drug targets based on genomic sequence data |
| US6686310B1 (en) | 1999-02-09 | 2004-02-03 | E. I. Du Pont De Nemours And Company | High surface area sol-gel route prepared hydrogenation catalysts |
| US6365376B1 (en) | 1999-02-19 | 2002-04-02 | E. I. Du Pont De Nemours And Company | Genes and enzymes for the production of adipic acid intermediates |
| AU3516100A (en) | 1999-03-05 | 2000-09-21 | Monsanto Technology Llc | Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways |
| DE60029440T2 (de) | 1999-05-21 | 2007-02-08 | Cargill Dow LLC, Minnetonka | Methoden und materialien zur synthese von organischen produkten |
| AU7093600A (en) | 1999-08-30 | 2001-03-26 | Wisconsin Alumni Research Foundation | Production of 3-hydroxypropionic acid in recombinant organisms |
| US6852517B1 (en) | 1999-08-30 | 2005-02-08 | Wisconsin Alumni Research Foundation | Production of 3-hydroxypropionic acid in recombinant organisms |
| US6660857B2 (en) | 2000-02-03 | 2003-12-09 | Dsm N.V. | Process for the preparation of ε-caprolactam |
| US6878861B2 (en) | 2000-07-21 | 2005-04-12 | Washington State University Research Foundation | Acyl coenzyme A thioesterases |
| ATE332390T1 (de) | 2000-07-25 | 2006-07-15 | Emmaus Foundation Inc | Verfahren zur produktionssteigerung von die fermentativen erzeugnung von ethanol |
| US7186541B2 (en) | 2000-11-20 | 2007-03-06 | Cargill, Incorporated | 3-hydroxypropionic acid and other organic compounds |
| CA2430270A1 (en) | 2000-11-22 | 2002-05-30 | Cargill Dow Polymers, Llc | Methods and materials for the synthesis of organic products |
| CN1358841A (zh) | 2000-12-11 | 2002-07-17 | 云南省微生物研究所 | 云南链霉菌 |
| EP1354955A4 (en) | 2000-12-28 | 2005-01-05 | Toyota Motor Co Ltd | PROCESS FOR PREPARING PRENYL ALCOHOL |
| JP4776146B2 (ja) | 2001-01-10 | 2011-09-21 | ザ・ペン・ステート・リサーチ・ファンデーション | 細胞代謝をモデル化する方法及びシステム |
| US7127379B2 (en) | 2001-01-31 | 2006-10-24 | The Regents Of The University Of California | Method for the evolutionary design of biochemical reaction networks |
| CA2439260C (en) | 2001-03-01 | 2012-10-23 | The Regents Of The University Of California | Models and methods for determining systemic properties of regulated reaction networks |
| US6743610B2 (en) | 2001-03-30 | 2004-06-01 | The University Of Chicago | Method to produce succinic acid from raw hydrolysates |
| BR0209491A (pt) | 2001-05-07 | 2004-10-13 | Cargil Inc | Processo para preparar ácidos carboxìlicos e derivados destes |
| WO2003010322A1 (en) | 2001-07-20 | 2003-02-06 | Youming Zhang | Improved rect or recet cloning and subcloning method |
| CA2356540A1 (en) | 2001-08-30 | 2003-02-28 | Emory University | Expressed dna sequences involved in mitochondrial functions |
| MXPA04004194A (es) | 2001-11-02 | 2005-03-31 | Rice University | Sistema de recirculacion para la manipulacion de disponibilidad de nadh intracelular. |
| EP1575881B1 (en) | 2002-01-18 | 2009-05-27 | Novozymes A/S | Alanine 2,3- aminomutase |
| US20070117191A1 (en) | 2002-02-06 | 2007-05-24 | Harumi Kamachi | Reductase gene for alpha-substituted-alpha, beta-unsaturated carbonyl compound |
| US20030224363A1 (en) | 2002-03-19 | 2003-12-04 | Park Sung M. | Compositions and methods for modeling bacillus subtilis metabolism |
| CA2480216A1 (en) | 2002-03-29 | 2003-10-09 | Genomatica, Inc. | Human metabolic models and methods |
| JPWO2003095651A1 (ja) | 2002-05-10 | 2005-09-15 | 協和醗酵工業株式会社 | メバロン酸の製造方法 |
| EP1513946B1 (en) | 2002-06-14 | 2007-05-16 | DSM IP Assets B.V. | Polypeptides having alpha-h-alpha amino acid amide racemase activity and nucleic acids encoding the same |
| US7856317B2 (en) | 2002-06-14 | 2010-12-21 | Genomatica, Inc. | Systems and methods for constructing genomic-based phenotypic models |
| JP4418793B2 (ja) | 2002-07-10 | 2010-02-24 | ザ ペン ステート リサーチ ファウンデーション | 遺伝子ノックアウト戦略を決定する方法 |
| US7826975B2 (en) | 2002-07-10 | 2010-11-02 | The Penn State Research Foundation | Method for redesign of microbial production systems |
| AU2003253949A1 (en) | 2002-07-15 | 2004-02-02 | Kosan Biosciences, Inc. | Metabolic pathways for starter units in polyketide biosynthesis |
| US7371558B2 (en) | 2002-10-04 | 2008-05-13 | E.I. Du Pont De Nemours And Company | Process for the biological production of 1,3-propanediol with high yield |
| CA2500761C (en) | 2002-10-15 | 2012-11-20 | Bernhard O. Palsson | Methods and systems to identify operational reaction pathways |
| WO2004044210A2 (en) | 2002-11-06 | 2004-05-27 | University Of Florida | Materials and methods for the efficient production of acetate and other products |
| WO2004074495A1 (ja) | 2003-02-24 | 2004-09-02 | Research Institute Of Innovative Technology For The Earth | 微生物による高効率水素製造方法 |
| RU2268300C2 (ru) | 2003-04-07 | 2006-01-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA |
| US7927859B2 (en) | 2003-08-22 | 2011-04-19 | Rice University | High molar succinate yield bacteria by increasing the intracellular NADH availability |
| JP4619291B2 (ja) | 2003-09-17 | 2011-01-26 | 三菱化学株式会社 | 非アミノ有機酸の製造方法 |
| EP1664286A1 (en) | 2003-09-18 | 2006-06-07 | Ciba SC Holding AG | Alcohol dehydrogenases with increased solvent and temperature stability |
| FR2862068B1 (fr) | 2003-11-06 | 2007-10-12 | Metabolic Explorer Sa | Souches de microorganismes optimisees pour des voies de biosyntheses consommatrices de nadph |
| US7244610B2 (en) | 2003-11-14 | 2007-07-17 | Rice University | Aerobic succinate production in bacteria |
| FR2864967B1 (fr) | 2004-01-12 | 2006-05-19 | Metabolic Explorer Sa | Microorganisme evolue pour la production de 1,2-propanediol |
| AU2005205188B2 (en) | 2004-01-19 | 2010-11-11 | Genomatica, Inc. | Biochemical synthesis of 6-amino caproic acid |
| US7608700B2 (en) | 2004-03-08 | 2009-10-27 | North Carolina State University | Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor |
| DE102004031177A1 (de) | 2004-06-29 | 2006-01-19 | Henkel Kgaa | Neue Geruchsstoffe bildende Genprodukte von Bacillus licheniformis und darauf aufbauende verbesserte biotechnologische Produktionsverfahren |
| US7262046B2 (en) | 2004-08-09 | 2007-08-28 | Rice University | Aerobic succinate production in bacteria |
| JP4771437B2 (ja) | 2004-08-27 | 2011-09-14 | ライス ユニバーシティー | 増加したコハク酸産生を有する変異Ｅ．ｃｏｌｉ株 |
| US8604180B2 (en) | 2004-09-09 | 2013-12-10 | Research Institute Of Innovative Technology For The Earth | DNA fragment having promoter function |
| CN101023178A (zh) | 2004-09-17 | 2007-08-22 | 莱斯大学 | 高琥珀酸产出细菌 |
| US7569380B2 (en) | 2004-12-22 | 2009-08-04 | Rice University | Simultaneous anaerobic production of isoamyl acetate and succinic acid |
| JP2006204255A (ja) | 2005-01-31 | 2006-08-10 | Canon Inc | アセチル−ＣｏＡアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法 |
| WO2006109312A2 (en) | 2005-04-15 | 2006-10-19 | Vascular Biogenics Ltd. | Compositions containing beta 2-glycoprotein i-derived peptides for the prevention and/or treatment of vascular disease |
| US8187842B2 (en) | 2005-06-20 | 2012-05-29 | Archer Daniels Midland Company | Altered glyoxylate shunt for improved production of aspartate-derived amino acids and chemicals |
| KR100676160B1 (ko) | 2005-08-19 | 2007-02-01 | 한국과학기술원 | 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법 |
| KR100679638B1 (ko) | 2005-08-19 | 2007-02-06 | 한국과학기술원 | 포메이트 디하이드로게나제 ｄ 또는 ｅ를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법 |
| AU2006287257A1 (en) | 2005-09-09 | 2007-03-15 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of succinate |
| US9297028B2 (en) | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| EP3301182B1 (en) | 2005-10-26 | 2020-03-18 | Butamax (TM) Advanced Biofuels LLC | Fermentative production of four carbon alcohols |
| NZ572363A (en) | 2006-05-01 | 2012-12-21 | Univ Florida | Ethanol production in non-recombinant bacterium comprising a mutation that affects nadh production |
| US8962298B2 (en) | 2006-05-02 | 2015-02-24 | Butamax Advanced Biofuels Llc | Recombinant host cell comprising a diol dehydratase |
| DE102006025821A1 (de) | 2006-06-02 | 2007-12-06 | Degussa Gmbh | Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd |
| RU2311231C1 (ru) | 2006-08-15 | 2007-11-27 | ООО "Объединенный центр исследований и разработок" | Катализатор для получения эфиров акриловой кислоты по реакции метатезиса диалкилмалеатов (варианты) и каталитическая композиция на его основе |
| EP2064321B1 (en) | 2006-08-30 | 2016-03-09 | Cargill, Incorporated | Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production |
| US8017364B2 (en) | 2006-12-12 | 2011-09-13 | Butamax(Tm) Advanced Biofuels Llc | Solvent tolerant microorganisms |
| EP2121949B1 (en) | 2006-12-21 | 2013-05-08 | GEVO, Inc. | Butanol production by metabolically engineered yeast |
| TWI568847B (zh) * | 2007-03-16 | 2017-02-01 | 奇諾麥提卡公司 | 用於１，４-丁二醇及其前驅物之生物合成的組合物及方法 |
| EP2147111A4 (en) * | 2007-04-18 | 2010-06-23 | Gevo Inc | MANIPULATED MICROORGANISMS FOR THE MANUFACTURE OF ISOPROPANOL |
| US20080274522A1 (en) | 2007-05-02 | 2008-11-06 | Bramucci Michael G | Method for the production of 2-butanone |
| US8426174B2 (en) | 2007-05-02 | 2013-04-23 | Butamax(Tm) Advanced Biofuels Llc | Method for the production of 2-butanol |
| EP2152852A2 (en) * | 2007-05-17 | 2010-02-17 | Tetravitae Bioscience, Inc. | Methods and compositions for producing solvents |
| BRPI0812515A2 (pt) | 2007-06-15 | 2014-12-30 | Evonik Degussa Gmbh | Micro-organismo com sistema de vitamina b12 desregulado |
| EP2017344A1 (en) | 2007-07-20 | 2009-01-21 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | Production of itaconic acid |
| US7947483B2 (en) | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
| EP2182051A4 (en) * | 2007-08-29 | 2010-12-29 | Res Inst Innovative Tech Earth | FOR THE MANUFACTURE OF ISOPROPANOL SUITABLE TRANSFORMERS |
| KR101042242B1 (ko) | 2007-09-07 | 2011-06-17 | 한국과학기술원 | 1,4-부탄디올 생성능을 가지는 변이체 및 이를 이용한1,4-부탄디올의 제조방법 |
| CN101903530A (zh) * | 2007-10-12 | 2010-12-01 | 加利福尼亚大学董事会 | 被改造以产生异丙醇的微生物 |
| CN107090424A (zh) | 2008-01-22 | 2017-08-25 | 基因组股份公司 | 利用合成气或其它气态碳源和甲醇的方法和有机体 |
| WO2009103026A1 (en) | 2008-02-15 | 2009-08-20 | Gevo, Inc. | Engineered microorganisms for producing isopropanol |
| CN102026960B (zh) | 2008-03-11 | 2014-07-16 | 帝斯曼知识产权资产管理有限公司 | 从5-甲酰缬草酸制备6-氨基己酸 |
| CN109468348B (zh) | 2008-03-11 | 2023-05-16 | 基因组股份公司 | 己二酸酯或硫代酯合成 |
| PL2265709T3 (pl) | 2008-03-27 | 2018-05-30 | Genomatica, Inc. | Mikroorganizmy do produkcji kwasu adypinowego i innych związków |
| WO2009131040A1 (ja) | 2008-04-25 | 2009-10-29 | 財団法人地球環境産業技術研究機構 | イソプロパノール生産能を有するコリネ型細菌の形質転換体 |
| WO2009155382A1 (en) | 2008-06-17 | 2009-12-23 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
| US8357826B2 (en) | 2008-10-16 | 2013-01-22 | Karl Kharas | Methods and apparatus for synthesis of alcohols from syngas |
-
2010
- 2010-04-30 BR BRPI1013505A patent/BRPI1013505A2/pt not_active IP Right Cessation
- 2010-04-30 KR KR1020117028541A patent/KR20120068763A/ko not_active Withdrawn
- 2010-04-30 AU AU2010242849A patent/AU2010242849A1/en not_active Abandoned
- 2010-04-30 US US12/772,094 patent/US8993285B2/en not_active Expired - Fee Related
- 2010-04-30 JP JP2012508799A patent/JP2012525156A/ja active Pending
- 2010-04-30 EP EP10770455A patent/EP2425006A4/en not_active Withdrawn
- 2010-04-30 WO PCT/US2010/033271 patent/WO2010127303A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012525158A5 (enExample) | ||
| US12529078B2 (en) | Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis | |
| JP2016063823A5 (enExample) | ||
| JP2012526561A5 (enExample) | ||
| Jang et al. | Bio‐based production of C2–C6 platform chemicals | |
| US12398396B2 (en) | Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol | |
| US20220056488A1 (en) | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene | |
| Lehmann et al. | Modifying the product pattern of Clostridium acetobutylicum: physiological effects of disrupting the acetate and acetone formation pathways | |
| KR102043381B1 (ko) | 2,4-펜타디에노에이트, 부타디엔, 프로필렌, 1,3-부탄디올 및 관련 알코올을 생합성하기 위한 미생물과 방법 | |
| Hou et al. | Engineering Clostridium acetobutylicum for alcohol production | |
| JP2021166530A (ja) | エネルギー発生発酵経路を含む遺伝子操作細菌 | |
| JP2012501678A5 (enExample) | ||
| CA2723877A1 (en) | A method for producing butanol using two-phase extractive fermentation | |
| JP2012525156A (ja) | イソプロパノール、ｎ−ブタノール、及びイソブタノールの産生のための微生物 | |
| US20250075235A1 (en) | Production of ethanol with one or more co-products in yeast | |
| CN110438056A (zh) | 一株产正丁酸的大肠杆菌工程菌的构建及应用 | |
| Wang et al. | Fermentative biobutanol production: an old topic with remarkable recent advances | |
| CA2892129C (en) | Recombinant clostridium with increased butanol productivity and method for producing butanol by using same | |
| Panchasara et al. | Biosynthetic pathway for production of renewable biofuels | |
| 박경혜 | Enhancement of isobutanol production in engineered Saccharomyces cerevisiae by optimizing cytosolic valine biosynthesis | |
| Zou et al. | Microbial conversion of bio-based chemicals: present and future prospects | |
| 김민지 | Production of isobutanol by pyruvate decarboxylase-deficient Saccharomyces cerevisiae | |
| Valada et al. | Butanol tolerance in Saccharomyces cerevisiae |