JP2012525156A5 - - Google Patents

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JP2012525156A5
JP2012525156A5 JP2012508799A JP2012508799A JP2012525156A5 JP 2012525156 A5 JP2012525156 A5 JP 2012525156A5 JP 2012508799 A JP2012508799 A JP 2012508799A JP 2012508799 A JP2012508799 A JP 2012508799A JP 2012525156 A5 JP2012525156 A5 JP 2012525156A5
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Japan
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coa
encoded
group
reductase
genes selected
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JP2012508799A
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JP2012525156A (ja
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Priority claimed from PCT/US2010/033271 external-priority patent/WO2010127303A1/en
Publication of JP2012525156A publication Critical patent/JP2012525156A/ja
Publication of JP2012525156A5 publication Critical patent/JP2012525156A5/ja
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JP2012508799A 2009-04-30 2010-04-30 イソプロパノール、n−ブタノール、及びイソブタノールの産生のための微生物 Pending JP2012525156A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17448209P 2009-04-30 2009-04-30
US61/174,482 2009-04-30
PCT/US2010/033271 WO2010127303A1 (en) 2009-04-30 2010-04-30 Organisms for the production of isopropanol, n-butanol, and isobutanol

Publications (2)

Publication Number Publication Date
JP2012525156A JP2012525156A (ja) 2012-10-22
JP2012525156A5 true JP2012525156A5 (https=) 2013-06-20

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JP2012508799A Pending JP2012525156A (ja) 2009-04-30 2010-04-30 イソプロパノール、n−ブタノール、及びイソブタノールの産生のための微生物

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US (1) US8993285B2 (https=)
EP (1) EP2425006A4 (https=)
JP (1) JP2012525156A (https=)
KR (1) KR20120068763A (https=)
AU (1) AU2010242849A1 (https=)
BR (1) BRPI1013505A2 (https=)
WO (1) WO2010127303A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0913901A2 (pt) 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
WO2010057022A1 (en) * 2008-11-14 2010-05-20 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
EP2373781A4 (en) * 2008-12-16 2012-10-10 Genomatica Inc MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS
EP2440669A4 (en) 2009-06-10 2013-08-28 Genomatica Inc MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL
DE102009046623A1 (de) * 2009-11-11 2011-05-12 Evonik Röhm Gmbh Verwendung eines zu einem MeaB-Protein homologen Proteins zur Erhöhung der enzymatischen Aktivität einer 3-Hydroxycarbonsäure-CoA-Mutase
KR20120120493A (ko) 2009-12-10 2012-11-01 게노마티카 인코포레이티드 합성 가스 또는 기타 가스상 탄소원 및 메탄올을 1,3-부탄디올로 변환하는 방법 및 변환용 유기체
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
CN103282376A (zh) 2010-10-29 2013-09-04 诺维信公司 具有琥珀酰CoA:乙酰乙酸转移酶活性的多肽及其编码多核苷酸
EP2678420A4 (en) * 2011-02-25 2014-10-29 Ohio State Innovation Foundation AUTOTROPHE HYDROGEN BACTERIA AND USES THEREOF
WO2012177599A2 (en) * 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for producing n-propanol 1, 3-propanediol, 1,2-propanediol or glycerol and methods related thereto
WO2012177601A2 (en) * 2011-06-22 2012-12-27 Genomatica, Inc. Microorganisms for producing isobutanol and methods related thereto
US9914947B2 (en) * 2011-07-27 2018-03-13 Alliance For Sustainable Energy, Llc Biological production of organic compounds
CN114395496A (zh) * 2012-03-06 2022-04-26 利戈斯股份有限公司 用于产生丙二酸的重组宿主细胞
KR102025458B1 (ko) 2012-10-08 2019-09-25 칼리스타, 인코포레이티드 가스 공급 발효 시스템
WO2014071286A1 (en) 2012-11-05 2014-05-08 Genomatica, Inc. Microorganisms for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,2-propanediol
US9469860B2 (en) * 2013-01-18 2016-10-18 Synata Bio, Inc. Method for production of n-butanol from syngas using syntrophic co-cultures of anaerobic microorganisms
US20140206066A1 (en) * 2013-01-18 2014-07-24 Coskata, Inc. Syntrophic co-culture of anaerobic microorganism for production of n-butanol from syngas
BR112015020904A2 (pt) 2013-03-15 2017-10-10 Genomatica Inc microrganismos e métodos para produção de butadieno e compostos relacionados por assimilação de formiato
WO2015084633A1 (en) 2013-12-03 2015-06-11 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
WO2015100338A2 (en) 2013-12-27 2015-07-02 Genomatica, Inc. Methods and organisms with increased carbon flux efficiencies
WO2016044713A1 (en) 2014-09-18 2016-03-24 Genomatica, Inc. Non-natural microbial organisms with improved energetic efficiency
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance

Family Cites Families (144)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3513209A (en) 1968-08-19 1970-05-19 Du Pont Method of making 1,4-cyclohexadiene
US4076948A (en) 1968-10-10 1978-02-28 El Paso Products Company Process for treatment of adipic acid mother liquor
GB1230276A (https=) 1968-12-09 1971-04-28
US3965182A (en) 1969-10-02 1976-06-22 Ethyl Corporation Preparation of aniline from phenol and ammonia
JPS506776Y1 (https=) 1969-12-27 1975-02-26
JPS4831084B1 (https=) 1970-09-04 1973-09-26
GB1344557A (en) 1972-06-23 1974-01-23 Mitsubishi Petrochemical Co Process for preparing 1,4-butanediol
JPS5543759B2 (https=) 1972-06-28 1980-11-07
DE2455617C3 (de) 1974-11-23 1982-03-18 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Butandiol und/oder Tetrahydrofuran über die Zwischenstufe des γ-Butyrolactons
DE2501499A1 (de) 1975-01-16 1976-07-22 Hoechst Ag Verfahren zur herstellung von butandiol-(1.4)
US4190495A (en) 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
US4301077A (en) 1980-12-22 1981-11-17 Standard Oil Company Process for the manufacture of 1-4-butanediol and tetrahydrofuran
IT1190783B (it) 1981-04-29 1988-02-24 Davy Mckee Oil & Chem Processo per l'idrogenolisi di esteri di acidi carbossilici
JPS6070088A (ja) * 1983-09-26 1985-04-20 Agency Of Ind Science & Technol イソプロパノ−ルの製造方法
JPS60114197A (ja) 1983-11-25 1985-06-20 Agency Of Ind Science & Technol 微生物によるジカルボン酸の製造法
US4871667A (en) 1984-11-26 1989-10-03 Agency Of Industrial Science & Technology Process for preparing muconic acid
US4652685A (en) 1985-11-15 1987-03-24 General Electric Company Hydrogenation of lactones to glycols
DE3783081T2 (de) 1986-06-11 1993-04-15 Michigan Biotech Inst Verfahren zur herstellung von bernsteinsaeure durch anaerobe fermentation.
US5143834A (en) 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5168055A (en) 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
US5182199A (en) 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
EP0633319B1 (en) 1988-04-27 1999-03-17 Daicel Chemical Industries, Ltd. Process for producing optically active 1,3-butanediol
EP0470172B1 (en) 1989-04-27 1995-06-28 BioControl Systems, Incorporated Precipitate test for microorganisms
JPH05506983A (ja) 1990-03-09 1993-10-14 バスフ ケイ アンド エフ コーポレイション 天然長鎖アルコールの製造方法
US5192673A (en) 1990-04-30 1993-03-09 Michigan Biotechnology Institute Mutant strain of C. acetobutylicum and process for making butanol
US5079143A (en) 1990-05-02 1992-01-07 The Upjohn Company Method of indentifying compounds useful as antiparasitic drugs
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
IL100572A (en) 1991-01-03 1997-01-10 Lepetit Spa Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them
US5416020A (en) 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
US6136577A (en) 1992-10-30 2000-10-24 Bioengineering Resources, Inc. Biological production of ethanol from waste gases with Clostridium ljungdahlii
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
FR2702492B1 (fr) 1993-03-12 1995-05-24 Rhone Poulenc Chimie Procédé de production par fermentation d'acide itaconique.
US5487987A (en) 1993-09-16 1996-01-30 Purdue Research Foundation Synthesis of adipic acid from biomass-derived carbon sources
US5521075A (en) 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
US5700934A (en) 1995-03-01 1997-12-23 Dsm N.V. Process for the preparation of epsilon-caprolactam and epsilon-caprolactam precursors
US5478952A (en) 1995-03-03 1995-12-26 E. I. Du Pont De Nemours And Company Ru,Re/carbon catalyst for hydrogenation in aqueous solution
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
FR2736927B1 (fr) 1995-07-18 1997-10-17 Rhone Poulenc Fibres & Polymer Enzymes a activite amidase, outils genetiques et microorganismes hotes permettant leur obtention et procede d'hydrolyse mettant en oeuvre lesdites enzymes
US5573931A (en) 1995-08-28 1996-11-12 Michigan Biotechnology Institute Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants
US5770435A (en) 1995-11-02 1998-06-23 University Of Chicago Mutant E. coli strain with increased succinic acid production
US5869301A (en) 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
JP2000506012A (ja) 1996-02-27 2000-05-23 ミシガン ステイト ユニヴァーシティー サーモアンエアロバクター・エタノリカス39eの第二級アルコールデヒドロゲナーゼをコードする遺伝子のクローニング及び発現並びに酵素の生化学的特徴付け
US5958745A (en) 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
KR100387301B1 (ko) 1996-07-01 2003-06-12 바이오 엔지니어링 리소스 인코포레이티드 폐가스로부터의 생성물의 생물학적 제조방법
KR100459818B1 (ko) 1996-09-02 2004-12-03 이. 아이. 두퐁 드 느무르 앤드 컴퍼니 ε-카프로락탐의 제조방법
WO1998036078A1 (en) 1997-02-13 1998-08-20 James Madison University Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units
KR100516986B1 (ko) 1997-02-19 2005-09-26 코닌클리즈케 디에스엠 엔.브이. 6-아미노카프론산 유도체를 과열 수증기와 접촉시킴으로써 촉매 없이 카프로락탐을 제조하는 방법
US6274790B1 (en) 1997-04-14 2001-08-14 The University Of British Columbia Nucleic acids encoding a plant enzyme involved in very long chain fatty acid synthesis
KR19990013007A (ko) 1997-07-31 1999-02-25 박원훈 형질전환된 대장균 ss373(kctc 8818p)과 이를 이용한숙신산의 생산방법
JPH11103863A (ja) 1997-10-08 1999-04-20 Nippon Shokubai Co Ltd マレイン酸異性化酵素遺伝子
US6280986B1 (en) 1997-12-01 2001-08-28 The United States Of America As Represented By The Secretary Of Agriculture Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities
US20030087381A1 (en) 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
WO1999053035A1 (en) 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
US6159738A (en) 1998-04-28 2000-12-12 University Of Chicago Method for construction of bacterial strains with increased succinic acid production
US6432686B1 (en) 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
US6444784B1 (en) 1998-05-29 2002-09-03 Exxonmobil Research & Engineering Company Wax crystal modifiers (LAW657)
DE19856136C2 (de) 1998-12-04 2002-10-24 Pasteur Institut Verfahren und Vorrichtung zur Selektion beschleunigter Proliferation lebender Zellen in Suspension
AU3482200A (en) 1999-02-02 2000-08-25 Bernhard Palsson Methods for identifying drug targets based on genomic sequence data
US6686310B1 (en) 1999-02-09 2004-02-03 E. I. Du Pont De Nemours And Company High surface area sol-gel route prepared hydrogenation catalysts
US6365376B1 (en) 1999-02-19 2002-04-02 E. I. Du Pont De Nemours And Company Genes and enzymes for the production of adipic acid intermediates
AU3516100A (en) 1999-03-05 2000-09-21 Monsanto Technology Llc Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
WO2000071738A1 (en) 1999-05-21 2000-11-30 Cargill Dow Llc Methods and materials for the synthesis of organic products
BR0008355A (pt) 1999-08-30 2002-07-16 Wisconsin Alumni Res Found Produção de ácido 3-hidroxipropionico em organismos recombinantes
US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US6660857B2 (en) 2000-02-03 2003-12-09 Dsm N.V. Process for the preparation of ε-caprolactam
US6878861B2 (en) 2000-07-21 2005-04-12 Washington State University Research Foundation Acyl coenzyme A thioesterases
WO2002008438A2 (en) 2000-07-25 2002-01-31 Bioengineering Resources, Inc. Methods for increasing the production of ethanol from microbial fermentation
BR0115877A (pt) 2000-11-20 2003-10-07 Cargill Inc ácido 3-hidroxipropiÈnico e outros compostos orgánicos
BR0115558A (pt) 2000-11-22 2004-08-17 Cargill Dow Polymers Llc ácido nucleico isolado, construção de expressão recombinante, célula de levedura transformada com a construção de expressão recombinante, e, método para produzir ácido lático
CN1358841A (zh) 2000-12-11 2002-07-17 云南省微生物研究所 云南链霉菌
EP1354955A4 (en) 2000-12-28 2005-01-05 Toyota Motor Co Ltd PROCESS FOR PREPARING PRENYL ALCOHOL
JP4776146B2 (ja) 2001-01-10 2011-09-21 ザ・ペン・ステート・リサーチ・ファンデーション 細胞代謝をモデル化する方法及びシステム
US7127379B2 (en) 2001-01-31 2006-10-24 The Regents Of The University Of California Method for the evolutionary design of biochemical reaction networks
JP2004533037A (ja) 2001-03-01 2004-10-28 ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア 調節された反応ネットワークの全体的特性を決定するためのモデルおよび方法
US6743610B2 (en) 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
ATE393137T1 (de) 2001-05-07 2008-05-15 Cargill Inc Verfahren zur herstellung von carbonsäuren und deren derivaten
EP1409702A1 (en) 2001-07-20 2004-04-21 Youming Zhang Improved rect or recet cloning and subcloning method
CA2356540A1 (en) 2001-08-30 2003-02-28 Emory University Expressed dna sequences involved in mitochondrial functions
CA2466133A1 (en) 2001-11-02 2003-05-15 Rice University Recycling system for manipulation of intracellular nadh availability
DE60327804D1 (de) 2002-01-18 2009-07-09 Novozymes As Alanin-2,3-aminomutase
EP1473368A4 (en) 2002-02-06 2006-01-25 Showa Denko Kk REDUCTASE GENE OF ALPHA SUBSTITUTED ALPHA, BETA-UNSATURATED CARBONYL COMPOUND
US20030224363A1 (en) 2002-03-19 2003-12-04 Park Sung M. Compositions and methods for modeling bacillus subtilis metabolism
AU2003222128A1 (en) 2002-03-29 2003-10-13 Genomatica, Inc. Human metabolic models and methods
EP1510583A1 (en) 2002-05-10 2005-03-02 Kyowa Hakko Kogyo Co., Ltd. Process for producing mevalonic acid
US7856317B2 (en) 2002-06-14 2010-12-21 Genomatica, Inc. Systems and methods for constructing genomic-based phenotypic models
EP1513946B1 (en) 2002-06-14 2007-05-16 DSM IP Assets B.V. Polypeptides having alpha-h-alpha amino acid amide racemase activity and nucleic acids encoding the same
JP4418793B2 (ja) 2002-07-10 2010-02-24 ザ ペン ステート リサーチ ファウンデーション 遺伝子ノックアウト戦略を決定する方法
US7826975B2 (en) 2002-07-10 2010-11-02 The Penn State Research Foundation Method for redesign of microbial production systems
US7413878B2 (en) 2002-07-15 2008-08-19 Kosan Biosciences, Inc. Recombinant host cells expressing atoAD and capable of making a polyketide using a starter unit
WO2004033646A2 (en) 2002-10-04 2004-04-22 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
WO2004035009A2 (en) 2002-10-15 2004-04-29 The Regents Of The University Of California Methods and systems to identify operational reaction pathways
WO2004044210A2 (en) 2002-11-06 2004-05-27 University Of Florida Materials and methods for the efficient production of acetate and other products
JP4275666B2 (ja) 2003-02-24 2009-06-10 財団法人地球環境産業技術研究機構 微生物による高効率水素製造方法
RU2268300C2 (ru) 2003-04-07 2006-01-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA
US7927859B2 (en) 2003-08-22 2011-04-19 Rice University High molar succinate yield bacteria by increasing the intracellular NADH availability
CN1852978A (zh) 2003-09-17 2006-10-25 三菱化学株式会社 制备无-氨基有机酸的方法
EP1664286A1 (en) 2003-09-18 2006-06-07 Ciba SC Holding AG Alcohol dehydrogenases with increased solvent and temperature stability
FR2862068B1 (fr) 2003-11-06 2007-10-12 Metabolic Explorer Sa Souches de microorganismes optimisees pour des voies de biosyntheses consommatrices de nadph
US7244610B2 (en) 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
FR2864967B1 (fr) 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
EP2194139A1 (en) 2004-01-19 2010-06-09 DSM IP Assets B.V. Biochemical synthesis of 6 amino caproic acid
US7608700B2 (en) 2004-03-08 2009-10-27 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor
DE102004031177A1 (de) 2004-06-29 2006-01-19 Henkel Kgaa Neue Geruchsstoffe bildende Genprodukte von Bacillus licheniformis und darauf aufbauende verbesserte biotechnologische Produktionsverfahren
WO2006020663A2 (en) 2004-08-09 2006-02-23 Rice University Aerobic succinate production in bacteria
KR101245428B1 (ko) 2004-08-27 2013-03-19 라이스 유니버시티 숙신산 생산이 증가된 돌연변이 대장균 균주
EP2434015B1 (en) 2004-09-09 2013-11-20 Research Institute Of Innovative Technology For The Earth DNA fragment having promoter function
CN101023178A (zh) 2004-09-17 2007-08-22 莱斯大学 高琥珀酸产出细菌
WO2006069174A2 (en) 2004-12-22 2006-06-29 Rice University Simultaneous anaerobic production of isoamyl acetate and succinic acid
JP2006204255A (ja) 2005-01-31 2006-08-10 Canon Inc アセチル−CoAアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法
EP1874334A4 (en) 2005-04-15 2011-03-30 Vascular Biogenics Ltd COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES
WO2007001982A1 (en) 2005-06-20 2007-01-04 Archer-Daniels-Midland Company Altered glyoxylate shunt for improved production of aspartate-derived amino acids and chemicals
KR100679638B1 (ko) 2005-08-19 2007-02-06 한국과학기술원 포메이트 디하이드로게나제 d 또는 e를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법
KR100676160B1 (ko) 2005-08-19 2007-02-01 한국과학기술원 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
CN101300356A (zh) 2005-09-09 2008-11-05 基因组股份公司 用于琥珀酸盐之生长关联性生产的方法和生物
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
MX359740B (es) 2005-10-26 2018-10-09 Du Pont Produccion fermentativa de alcoholes de cuatro atomos de carbono.
NZ600540A (en) 2006-05-01 2013-12-20 Univ Florida Ethanol production in non-recombinant hosts
US8206970B2 (en) 2006-05-02 2012-06-26 Butamax(Tm) Advanced Biofuels Llc Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase
DE102006025821A1 (de) 2006-06-02 2007-12-06 Degussa Gmbh Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd
RU2311231C1 (ru) 2006-08-15 2007-11-27 ООО "Объединенный центр исследований и разработок" Катализатор для получения эфиров акриловой кислоты по реакции метатезиса диалкилмалеатов (варианты) и каталитическая композиция на его основе
US8030045B2 (en) 2006-08-30 2011-10-04 Cargill, Incorporated Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production
US8017364B2 (en) 2006-12-12 2011-09-13 Butamax(Tm) Advanced Biofuels Llc Solvent tolerant microorganisms
BRPI0720566A2 (pt) 2006-12-21 2014-02-04 Gevo Inc Produção de butanol através de levedura metabolicamente projetada
BRPI0823327A2 (pt) 2007-03-16 2013-10-22 Genomatica Inc Biocatalisadores microbianos que não ocorrem naturalmente e métodos para a biosíntese de ácido 4-hidroxibutanóico e 1,4-butanodiol
US20080293125A1 (en) * 2007-04-18 2008-11-27 Gevo, Inc. Engineered microorganisms for producing isopropanol
US8426174B2 (en) 2007-05-02 2013-04-23 Butamax(Tm) Advanced Biofuels Llc Method for the production of 2-butanol
US20080274522A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of 2-butanone
WO2008144060A2 (en) * 2007-05-17 2008-11-27 Tetravitae Bioscience, Inc. Methods and compositions for producing solvents
CN101849017A (zh) 2007-06-15 2010-09-29 赢创德固赛有限责任公司 具有下调的维生素b12系统的微生物
EP2017344A1 (en) 2007-07-20 2009-01-21 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Production of itaconic acid
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
EP2182051A4 (en) * 2007-08-29 2010-12-29 Res Inst Innovative Tech Earth FOR THE MANUFACTURE OF ISOPROPANOL SUITABLE TRANSFORMERS
KR101042242B1 (ko) 2007-09-07 2011-06-17 한국과학기술원 1,4-부탄디올 생성능을 가지는 변이체 및 이를 이용한1,4-부탄디올의 제조방법
BRPI0817545A2 (pt) 2007-10-12 2014-11-25 Univ California Microorganismo recombinante, métodos para produzir um microorganismo recombinante e para produzir isopropanol, vetor recombinante, e, célula hospedeira recombinante.
CA2712779C (en) 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
WO2009103026A1 (en) 2008-02-15 2009-08-20 Gevo, Inc. Engineered microorganisms for producing isopropanol
TW202306945A (zh) 2008-03-11 2023-02-16 美商吉諾瑪蒂卡股份有限公司 由α-酮庚二酸製備6-胺己酸之技術
AU2009224087B2 (en) 2008-03-11 2015-04-16 Genomatica, Inc. Adipate ester or thioester synthesis
ES2656790T3 (es) 2008-03-27 2018-02-28 Genomatica, Inc. Microorganismos para la producción de ácido adípico y otros compuestos
JP5395063B2 (ja) 2008-04-25 2014-01-22 公益財団法人地球環境産業技術研究機構 イソプロパノール生産能を有するコリネ型細菌の形質転換体
BRPI0913901A2 (pt) 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
US8344188B2 (en) 2008-10-16 2013-01-01 Maverick Biofuels, Inc. Methods and apparatus for synthesis of alcohols from syngas

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