|
US4666828A
(en)
|
1984-08-15 |
1987-05-19 |
The General Hospital Corporation |
Test for Huntington's disease
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4801531A
(en)
|
1985-04-17 |
1989-01-31 |
Biotechnology Research Partners, Ltd. |
Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
|
|
US5272057A
(en)
|
1988-10-14 |
1993-12-21 |
Georgetown University |
Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
|
|
US5192659A
(en)
|
1989-08-25 |
1993-03-09 |
Genetype Ag |
Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
|
|
US5554630A
(en)
|
1993-03-24 |
1996-09-10 |
Neurosearch A/S |
Benzimidazole compounds
|
|
CA2191979A1
(en)
|
1994-06-20 |
1995-12-28 |
Muneo Takatani |
Condensed imidazole compounds, their production and use
|
|
WO1996034866A1
(en)
|
1995-05-01 |
1996-11-07 |
Fujisawa Pharmaceutical Co., Ltd. |
Imidazo 1,2-a pyridine and imidazo 1,2-a pyridezine derivatives and their use as bone resorption inhibitors
|
|
US6218529B1
(en)
|
1995-07-31 |
2001-04-17 |
Urocor, Inc. |
Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer
|
|
AU6966696A
(en)
|
1995-10-05 |
1997-04-28 |
Warner-Lambert Company |
Method for treating and preventing inflammation and atherosclerosis
|
|
AU747708B2
(en)
|
1996-07-24 |
2002-05-23 |
Du Pont Pharmaceuticals Company |
Azolo triazines and pyrimidines
|
|
CA2744096C
(en)
|
1996-07-31 |
2013-07-30 |
Laboratory Corporation Of America Holdings |
Biomarkers and targets for diagnosis, prognosis and management of prostate disease
|
|
CA2291709A1
(en)
|
1997-05-30 |
1998-12-03 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
US5990146A
(en)
|
1997-08-20 |
1999-11-23 |
Warner-Lambert Company |
Benzimidazoles for inhibiting protein tyrosine kinase mediated cellular proliferation
|
|
WO2000012089A1
(en)
|
1998-08-31 |
2000-03-09 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
US6465484B1
(en)
|
1997-09-26 |
2002-10-15 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
|
EP1344779B1
(en)
|
1998-01-28 |
2005-08-10 |
Bristol-Myers Squibb Pharma Company |
Azolo-pyrimidines
|
|
US6245759B1
(en)
|
1999-03-11 |
2001-06-12 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
CA2376957A1
(en)
|
1999-06-30 |
2001-01-04 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
|
WO2001000214A1
(en)
|
1999-06-30 |
2001-01-04 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
|
AU5636900A
(en)
|
1999-06-30 |
2001-01-31 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
|
JP2001057292A
(ja)
|
1999-08-20 |
2001-02-27 |
Toray Ind Inc |
発光素子
|
|
GB9919778D0
(en)
|
1999-08-21 |
1999-10-27 |
Zeneca Ltd |
Chemical compounds
|
|
GB9921150D0
(en)
|
1999-09-07 |
1999-11-10 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO2001021634A1
(en)
|
1999-09-21 |
2001-03-29 |
Lion Bioscience Ag |
Benzimidazole derivatives and combinatorial libraries thereof
|
|
GB9927687D0
(en)
|
1999-11-23 |
2000-01-19 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
AU2001237401B2
(en)
|
2000-03-01 |
2006-11-09 |
Janssen Pharmaceutica N.V. |
2,4-disubstituted thiazolyl derivatives
|
|
IL151517A0
(en)
|
2000-03-09 |
2003-04-10 |
Aventis Pharma Gmbh |
Therapeutic uses of ppar mediators
|
|
US20020041880A1
(en)
|
2000-07-05 |
2002-04-11 |
Defeo-Jones Deborah |
Method of treating cancer
|
|
AP1333A
(en)
|
2000-08-04 |
2004-11-28 |
Warner Lambert Co |
2-(4-pyridyl) amino-6-dialkoxyphenyl-pyrido [2,3-d] pyrimidin-7-ones.
|
|
AU2001295992A1
(en)
|
2000-10-24 |
2002-05-06 |
Sankyo Company Limited |
Imidazopyridine derivatives
|
|
GB0027561D0
(en)
|
2000-11-10 |
2000-12-27 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2004515496A
(ja)
|
2000-12-07 |
2004-05-27 |
アストラゼネカ・アクチエボラーグ |
ベンズイミダゾール治療剤
|
|
US20020107262A1
(en)
|
2000-12-08 |
2002-08-08 |
3M Innovative Properties Company |
Substituted imidazopyridines
|
|
GB0103926D0
(en)
|
2001-02-17 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
|
SE0100567D0
(sv)
|
2001-02-20 |
2001-02-20 |
Astrazeneca Ab |
Compounds
|
|
WO2002066480A2
(en)
|
2001-02-20 |
2002-08-29 |
Astrazeneca Ab |
2-arylamino-pyrimidines for the treatment of gsk3-related disorders
|
|
SE0100568D0
(sv)
|
2001-02-20 |
2001-02-20 |
Astrazeneca Ab |
Compounds
|
|
TWI248936B
(en)
|
2001-03-21 |
2006-02-11 |
Merck Sharp & Dohme |
Imidazo-pyrimidine derivatives as ligands for GABA receptors
|
|
DE10117183A1
(de)
|
2001-04-05 |
2002-10-10 |
Gruenenthal Gmbh |
Verwendung von substituierten Imidazo[1,2-a]-pyridinverbindungen als Arzneimittel
|
|
ATE402164T1
(de)
|
2001-04-26 |
2008-08-15 |
Eisai R&D Man Co Ltd |
Stickstoffhaltige verbindung mit kondensiertem ring und pyrazolylgruppe als substituent und medizinische zusammensetzung davon
|
|
WO2003007955A2
(en)
|
2001-07-20 |
2003-01-30 |
Cancer Research Technology Limited |
Biphenyl apurinic/apyrimidinic site endonuclease inhibitors to treat cancer
|
|
GB0128499D0
(en)
|
2001-11-28 |
2002-01-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US6900208B2
(en)
|
2002-03-28 |
2005-05-31 |
Bristol Myers Squibb Company |
Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders
|
|
JP2003295882A
(ja)
|
2002-04-02 |
2003-10-15 |
Canon Inc |
音声合成用テキスト構造、音声合成方法、音声合成装置及びそのコンピュータ・プログラム
|
|
KR20040097375A
(ko)
|
2002-04-23 |
2004-11-17 |
시오노기 앤드 컴파니, 리미티드 |
피라졸로[1, 5-에이]피리미딘 유도체 및 이를 함유한엔에이디(피)에이취 산화효소 저해제
|
|
JP2004002826A
(ja)
|
2002-04-24 |
2004-01-08 |
Sankyo Co Ltd |
高分子イミダゾピリジン誘導体
|
|
EP1503757B1
(en)
|
2002-05-02 |
2007-12-19 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
GB2398781B
(en)
|
2002-05-23 |
2005-02-02 |
Cytopia Pty Ltd |
Kinase inhibitors
|
|
GB0212049D0
(en)
|
2002-05-24 |
2002-07-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB0212048D0
(en)
|
2002-05-24 |
2002-07-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO2003101993A1
(en)
|
2002-06-04 |
2003-12-11 |
Neogenesis Pharmaceuticals, Inc. |
Pyrazolo` 1,5a! pyrimidine compounds as antiviral agents
|
|
PA8577501A1
(es)
|
2002-07-25 |
2004-02-07 |
Warner Lambert Co |
Inhibidores de quinasas
|
|
TWI351405B
(en)
|
2002-09-19 |
2011-11-01 |
Schering Corp |
Novel imidazopyridines as cyclin dependent kinase
|
|
GB0223349D0
(en)
|
2002-10-08 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
AU2003271185A1
(en)
|
2002-10-15 |
2004-05-04 |
Takeda Pharmaceutical Company Limited |
Imidazopyridine derivative, process for producing the same, and use
|
|
AU2003298942A1
(en)
|
2002-12-11 |
2004-06-30 |
Merck And Co., Inc. |
Tyrosine kinase inhibitors
|
|
AU2003299651A1
(en)
|
2002-12-11 |
2004-06-30 |
Merck And Co., Inc. |
Tyrosine kinase inhibitors
|
|
US7826979B2
(en)
|
2003-02-14 |
2010-11-02 |
Vertex Pharmaceuticals Incorporated |
Method of modeling complex formation between a query ligan and a target molecule
|
|
US7476670B2
(en)
|
2003-02-18 |
2009-01-13 |
Aventis Pharma S.A. |
Purine derivatives, method for preparing, pharmaceutical compositions and novel use
|
|
US7157460B2
(en)
|
2003-02-20 |
2007-01-02 |
Sugen Inc. |
Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
|
|
ES2423800T3
(es)
|
2003-03-28 |
2013-09-24 |
Novartis Vaccines And Diagnostics, Inc. |
Uso de compuestos orgánicos para la inmunopotenciación
|
|
EP1664021A1
(en)
|
2003-08-21 |
2006-06-07 |
OSI Pharmaceuticals, Inc. |
N-substituted benzimidazolyl c-kit inhibitors
|
|
US7442709B2
(en)
|
2003-08-21 |
2008-10-28 |
Osi Pharmaceuticals, Inc. |
N3-substituted imidazopyridine c-Kit inhibitors
|
|
KR20060119871A
(ko)
|
2003-08-21 |
2006-11-24 |
오에스아이 파마슈티컬스, 인코포레이티드 |
Ｎ３―치환된 이미다조피리딘 ｃ―ｋｉｔ 억제제
|
|
EP1689739B1
(en)
|
2003-12-03 |
2016-03-30 |
YM BioSciences Australia Pty Ltd |
Azole-based kinase inhibitors
|
|
EP1711496A4
(en)
|
2004-01-28 |
2009-02-11 |
Smithkline Beecham Corp |
THIAZOLE COMPOUNDS
|
|
TW200530236A
(en)
|
2004-02-23 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Heteroaryl phenylurea
|
|
US7566781B2
(en)
|
2004-05-10 |
2009-07-28 |
Banyu Pharmaceutical Co., Ltd. |
Imidazopyridine compound
|
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
|
CN101048406B
(zh)
|
2004-08-31 |
2010-12-22 |
万有制药株式会社 |
新型取代的咪唑衍生物
|
|
KR20070057965A
(ko)
|
2004-09-21 |
2007-06-07 |
신타 파마슈티칼스 코프. |
염증 및 면역 관련 용도를 위한 화합물
|
|
WO2006038001A1
(en)
|
2004-10-06 |
2006-04-13 |
Celltech R & D Limited |
Aminopyrimidine derivatives as jnk inhibitors
|
|
JP2008521903A
(ja)
|
2004-12-01 |
2008-06-26 |
オーエスアイ・ファーマスーティカルズ・インコーポレーテッド |
Ｎ置換されたベンズイミダゾリルＣ−ｋｉｔ阻害剤及びコンビナトリアルベンゾイミダゾールライブラリー
|
|
US20080167314A1
(en)
|
2004-12-28 |
2008-07-10 |
Osamu Uchikawa |
Condensed Imidazole Compound And Use Thereof
|
|
WO2006070198A1
(en)
|
2004-12-30 |
2006-07-06 |
Astex Therapeutics Limited |
Pyrazole derivatives as that modulate the activity of cdk, gsk and aurora kinases
|
|
DOP2006000051A
(es)
|
2005-02-24 |
2006-08-31 |
Lilly Co Eli |
Inhibidores de vegf-r2 y métodos
|
|
EP1853590A1
(en)
|
2005-03-03 |
2007-11-14 |
Sirtris Pharmaceuticals, Inc. |
Fused heterocyclic compounds and their use as sirtuin modulators
|
|
EP1874772A1
(en)
|
2005-04-05 |
2008-01-09 |
Pharmacopeia, Inc. |
Purine and imidazopyridine derivatives for immunosuppression
|
|
FR2884821B1
(fr)
|
2005-04-26 |
2007-07-06 |
Aventis Pharma Sa |
Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
|
|
US7572807B2
(en)
|
2005-06-09 |
2009-08-11 |
Bristol-Myers Squibb Company |
Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
|
|
BRPI0616722A2
(pt)
|
2005-09-30 |
2012-12-25 |
Astrazeneca Ab |
composto ou um sal farmaceuticamente aceitÁvel ou um Éster hidrolisÁvel in vivo do mesmo, processo para preparar o mesmo, composiÇço farmacÊutica, uso de um composto ou um sal farmaceuticamente aceitÁvel ou um Éster hidrolisÁvel in vivo do mesmo, e, mÉtodos para produzir um efeito anti-proliferaÇço celular e um efeito inibidor cdk2, para tratar cÂncer, e para tratar doenÇas
|
|
EP2001476A4
(en)
|
2006-03-20 |
2010-12-22 |
Synta Pharmaceuticals Corp |
BENZOIMIDAZOLYL-PARAZINE-BASED COMPOUNDS FOR INFLAMMATION USES AND IMMUNE DISORDERS
|
|
AU2007230911A1
(en)
|
2006-03-23 |
2007-10-04 |
Synta Pharmaceuticals Corp. |
Benzimidazolyl-pyridine compounds for inflammation and immune-related uses
|
|
ITVA20060041A1
(it)
|
2006-07-05 |
2008-01-06 |
Dialectica Srl |
Uso di composti derivati amminotiazolici, di loro composizioni farmaceutiche, nel trattamento di malattie caratterizzate dalla anormale repressione della trascrizione genica, particolarmente il morbo di huntington
|
|
TW200811134A
(en)
|
2006-07-12 |
2008-03-01 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
EP1882475A1
(en)
|
2006-07-26 |
2008-01-30 |
Novartis AG |
Method of treating disorders mediated by the fibroblast growth factor receptor
|
|
US7737149B2
(en)
|
2006-12-21 |
2010-06-15 |
Astrazeneca Ab |
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide and salts thereof
|
|
US8131527B1
(en)
|
2006-12-22 |
2012-03-06 |
Astex Therapeutics Ltd. |
FGFR pharmacophore compounds
|
|
US8895745B2
(en)
*
|
2006-12-22 |
2014-11-25 |
Astex Therapeutics Limited |
Bicyclic heterocyclic compounds as FGFR inhibitors
|
|
CN101679409B
(zh)
|
2006-12-22 |
2014-11-26 |
Astex治疗学有限公司 |
双环杂环衍生化合物、其医药组合物和其用途
|
|
US7977336B2
(en)
|
2006-12-28 |
2011-07-12 |
Banyu Pharmaceutical Co. Ltd |
Aminopyrimidine derivatives as PLK1 inhibitors
|
|
BRPI0809998B8
(pt)
|
2007-04-03 |
2021-05-25 |
Array Biopharma Inc |
composto de imidazo[1,2-a] piridina como inibidores do receptor tirosina quinase, seus usos, seus processos de preparação e composições farmacêuticas
|
|
CN107021895A
(zh)
|
2007-06-12 |
2017-08-08 |
尔察祯有限公司 |
抗菌剂
|
|
US20090005374A1
(en)
|
2007-06-26 |
2009-01-01 |
Melvin Jr Lawrence S |
Imidazopyridinyl thiazolyl histone deacetylase inhibitors
|
|
GB0720038D0
(en)
|
2007-10-12 |
2007-11-21 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0720041D0
(en)
|
2007-10-12 |
2007-11-21 |
Astex Therapeutics Ltd |
New Compounds
|
|
GB0810902D0
(en)
*
|
2008-06-13 |
2008-07-23 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0906470D0
(en)
|
2009-04-15 |
2009-05-20 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0906472D0
(en)
|
2009-04-15 |
2009-05-20 |
Astex Therapeutics Ltd |
New compounds
|
