JP2012523576A - 試料中の分析物の存在を検出するための方法および装置 - Google Patents

試料中の分析物の存在を検出するための方法および装置 Download PDF

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JP2012523576A
JP2012523576A JP2012506135A JP2012506135A JP2012523576A JP 2012523576 A JP2012523576 A JP 2012523576A JP 2012506135 A JP2012506135 A JP 2012506135A JP 2012506135 A JP2012506135 A JP 2012506135A JP 2012523576 A JP2012523576 A JP 2012523576A
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JP2012523576A5 (enExample
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ギャスター,リチャード
ホール,ドリュー
ワン,シャン,エックス.
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Leland Stanford Junior University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering
    • G01N21/658Raman scattering enhancement Raman, e.g. surface plasmons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/02Mechanical
    • G01N2201/022Casings
    • G01N2201/0221Portable; cableless; compact; hand-held
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2012506135A 2009-04-13 2010-04-13 試料中の分析物の存在を検出するための方法および装置 Pending JP2012523576A (ja)

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Application Number Priority Date Filing Date Title
US16892209P 2009-04-13 2009-04-13
US61/168,922 2009-04-13
PCT/US2010/030919 WO2011022093A2 (en) 2009-04-13 2010-04-13 Methods and devices for detecting the presence of an analyte in a sample

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JP2012523576A true JP2012523576A (ja) 2012-10-04
JP2012523576A5 JP2012523576A5 (enExample) 2013-04-11

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US (1) US9506919B2 (enExample)
EP (1) EP2419733A4 (enExample)
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JP2016540537A (ja) * 2013-10-23 2016-12-28 ヴェリリー ライフ サイエンシズ エルエルシー 変調源を有する非侵襲的な分析物検出システム
JP2016540534A (ja) * 2013-10-23 2016-12-28 ヴェリリー ライフ サイエンシズ エルエルシー 分析物と背景信号とを区別するための応答信号の変調
JP2016540539A (ja) * 2013-10-23 2016-12-28 ヴェリリー ライフ サイエンシズ エルエルシー 外部磁界による血管系内の磁性粒子の空間変調
JP2017502266A (ja) * 2013-12-04 2017-01-19 エスピーディー スイス プレシジョン ダイアゴスチックス ゲーエムベーハー アッセイデバイス
JP2017525983A (ja) * 2014-08-29 2017-09-07 マルクメトリックス・インコーポレイテッド ポータブル分析機器
JP2018517154A (ja) * 2015-06-12 2018-06-28 カッポ,アンソニー,ピー. 手持ち式フィールドポータブル表面プラズモン共鳴装置および化学および生物学的薬剤の検出におけるその用途
US10682050B2 (en) 2015-09-24 2020-06-16 Lacrisciences, Llc Optical sensors, systems and methods of using same
US11016025B2 (en) 2015-11-10 2021-05-25 Lacrisciences, Llc Systems and methods for determining sample osmolarity
WO2023079962A1 (ja) * 2021-11-04 2023-05-11 株式会社日立ハイテク 免疫分析方法および免疫分析装置

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JP6023509B2 (ja) 2012-08-10 2016-11-09 浜松ホトニクス株式会社 表面増強ラマン散乱ユニット
CN108827928B (zh) * 2012-08-10 2021-12-24 浜松光子学株式会社 表面增强拉曼散射单元及其使用方法
JP6080648B2 (ja) * 2013-03-29 2017-02-15 浜松ホトニクス株式会社 表面増強ラマン散乱ユニット
JP6055234B2 (ja) 2012-08-10 2016-12-27 浜松ホトニクス株式会社 表面増強ラマン散乱ユニット
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JP6151948B2 (ja) 2013-03-29 2017-06-21 浜松ホトニクス株式会社 表面増強ラマン散乱ユニット及びラマン分光分析方法
EP2884264B1 (en) 2012-08-10 2019-11-20 Hamamatsu Photonics K.K. Surface-enhanced raman scattering element, and method for producing same
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JP2018500539A (ja) * 2014-10-24 2018-01-11 モナシュ ユニバーシティ 血液中の病原体の検出のための方法およびシステム
CN107923877B (zh) 2015-05-12 2021-07-09 马格雷股份有限公司 用于提高磁传感器灵敏度的装置和方法
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JP6282762B2 (ja) * 2017-01-17 2018-02-21 浜松ホトニクス株式会社 表面増強ラマン散乱ユニット
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WO2021006356A1 (ja) * 2019-07-11 2021-01-14 シチズン時計株式会社 被測定物質の検知装置
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