JP2012518669A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012518669A5 JP2012518669A5 JP2011551471A JP2011551471A JP2012518669A5 JP 2012518669 A5 JP2012518669 A5 JP 2012518669A5 JP 2011551471 A JP2011551471 A JP 2011551471A JP 2011551471 A JP2011551471 A JP 2011551471A JP 2012518669 A5 JP2012518669 A5 JP 2012518669A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- amino acids
- surface active
- natural
- active protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000018102 proteins Nutrition 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 235000001014 amino acid Nutrition 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- XUJNEKJLAYXESH-REOHCLBHSA-N L-cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N L-serine Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims 2
- 235000018417 cysteine Nutrition 0.000 claims 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- 239000004471 Glycine Substances 0.000 claims 1
- -1 His Chemical compound 0.000 claims 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 1
- 125000000393 L-methionino group Chemical group [H]OC(=O)[C@@]([H])(N([H])[*])C([H])([H])C(SC([H])([H])[H])([H])[H] 0.000 claims 1
- 125000000174 L-prolyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(*)=O 0.000 claims 1
- 125000000510 L-tryptophano group Chemical group [H]C1=C([H])C([H])=C2N([H])C([H])=C(C([H])([H])[C@@]([H])(C(O[H])=O)N([H])[*])C2=C1[H] 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- 239000004473 Threonine Substances 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 150000001945 cysteines Chemical class 0.000 claims 1
- 125000000267 glycino group Chemical group [H]N([*])C([H])([H])C(=O)O[H] 0.000 claims 1
- 235000004400 serine Nutrition 0.000 claims 1
Claims (2)
- 前記表面活性タンパク質が、未改質又はグリコシル化、アシル化又は架橋されていてよい、天然又は組換えハイドロフォビンから選択される1つ以上のタンパク質である、請求項1又は2に記載の使用。
- 前記表面活性タンパク質が、一般構造式(I)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09153770.4 | 2009-02-26 | ||
EP09153770 | 2009-02-26 | ||
PCT/EP2010/052125 WO2010097344A1 (en) | 2009-02-26 | 2010-02-19 | Compositions, use and method for the use of surface active proteins in topical drug delivery across keratin |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2012518669A JP2012518669A (ja) | 2012-08-16 |
JP2012518669A5 true JP2012518669A5 (ja) | 2014-07-31 |
JP5832302B2 JP5832302B2 (ja) | 2015-12-16 |
Family
ID=40834317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011551471A Expired - Fee Related JP5832302B2 (ja) | 2009-02-26 | 2010-02-19 | ケラチンへの局所薬剤デリバリーにおける表面活性タンパク質の組成物、使用及び使用方法 |
Country Status (8)
Country | Link |
---|---|
US (1) | US8758730B2 (ja) |
EP (1) | EP2400988B1 (ja) |
JP (1) | JP5832302B2 (ja) |
KR (1) | KR20110130440A (ja) |
CN (1) | CN102333546B (ja) |
CA (1) | CA2784516C (ja) |
WO (1) | WO2010097344A1 (ja) |
ZA (1) | ZA201203028B (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013113451A2 (en) * | 2012-01-31 | 2013-08-08 | Unilever Plc | Personal care composition |
EP2884975B1 (en) | 2012-08-16 | 2019-07-31 | Dusa Pharmaceuticals, Inc. | Phototherapeutic agent for use in a method of treating onychomycosis |
CN103980353A (zh) * | 2014-05-21 | 2014-08-13 | 乔明强 | 一种疏水蛋白及其组成的药物制剂 |
RU2759134C2 (ru) * | 2015-10-26 | 2021-11-09 | Басф Се | Продукты и способы для ухода за полостью рта, содержащие hlp |
CN112198315B (zh) * | 2020-09-11 | 2023-10-27 | 杭州奥泰生物技术股份有限公司 | 一种采集及检测指甲或趾甲样本中滥用药物的方法 |
CN112791048B (zh) * | 2020-12-31 | 2023-01-17 | 海南海神同洲制药有限公司 | 一种硝酸舍他康唑栓及其制备方法 |
CN115701464B (zh) * | 2021-08-02 | 2024-06-11 | 江苏金太阳纺织科技股份有限公司 | 超疏水整理剂及其制备方法与应用 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3807915A1 (de) * | 1988-03-10 | 1989-09-21 | Wella Ag | Mittel zur festigung der frisur und pflege des haares |
FR2673537B1 (fr) | 1991-03-08 | 1993-06-11 | Oreal | Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes. |
WO1996041882A1 (en) | 1995-06-12 | 1996-12-27 | Proefstation Voor De Champignoncultuur | Hydrophobins from edible fungi, genes, nucleotide sequences and dna-fragments encoding for said hydrophobins, and expression thereof |
WO1997009960A1 (en) * | 1995-09-14 | 1997-03-20 | Sorenson Pharmaceutical, Inc. | Composition and method for treating diseased nails |
JP4227677B2 (ja) * | 1996-12-10 | 2009-02-18 | 杏林製薬株式会社 | 被膜形成性抗真菌剤組成物 |
US6517863B1 (en) * | 1999-01-20 | 2003-02-11 | Usbiomaterials Corporation | Compositions and methods for treating nails and adjacent tissues |
GB0019283D0 (en) * | 2000-08-04 | 2000-09-27 | Novartis Ag | Organic compounds |
FR2833490B1 (fr) | 2001-12-14 | 2004-12-10 | Oreal | Utilisition cosmetique d'au moins une hydrophobine pour le traitement des matieres keratiniques et compositions mises en oeuvre |
US6899890B2 (en) * | 2002-03-20 | 2005-05-31 | Kv Pharmaceutical Company | Bioadhesive drug delivery system |
DE60303207T2 (de) | 2002-06-21 | 2006-09-14 | Applied Nanosystems B.V. | Verfahren zur bindung einer verbindung an eine oberfläche |
US7892788B2 (en) | 2005-02-07 | 2011-02-22 | Basf Se | Hydrophobin fusion products, production and use thereof |
WO2006103230A1 (de) | 2005-03-30 | 2006-10-05 | Basf Aktiengesellschaft | Verwendung von hydrophobinen zur oberflächenbehandlung von gehärteten mineralischen baustoffen, naturstein, kunststein und keramiken |
WO2006103638A2 (en) | 2005-03-31 | 2006-10-05 | Ranbaxy Laboratories Limited | Topical pharmaceutical compositions of terbinafine and processes for their preparation |
WO2006103251A1 (de) | 2005-04-01 | 2006-10-05 | Basf Aktiengesellschaft | Verwendung von proteinen als demulgatoren |
DE102005029704A1 (de) * | 2005-06-24 | 2007-01-11 | Basf Ag | Verwendung von Hydrophobin-Polypeptiden sowie Konjugaten aus Hydrophobin-Polypeptiden mit Wirk-oder Effektstoffen und ihre Herstellung sowie deren Einsatz in der Kosmetik |
DE102005033002A1 (de) | 2005-07-14 | 2007-01-18 | Basf Ag | Wässrige Monomeremulsionen enthaltend Hydrophobin |
FR2892023B1 (fr) * | 2005-10-14 | 2009-09-25 | Galderma Sa | Composition pharmaceutique a base d'amorolfine et d'agent filmogene hydrosoluble pour application ungueale et peri-ungueale |
US20100166627A1 (en) | 2007-05-24 | 2010-07-01 | Basf Se | Use of hydrophobins as additives in the crystallization of solids |
RU2491096C9 (ru) * | 2007-09-13 | 2014-02-10 | Басф Се | Применение гидрофобин-полипептидов в качестве усилителя пенетрации |
JP2011527668A (ja) | 2008-07-11 | 2011-11-04 | ビーエーエスエフ ソシエタス・ヨーロピア | 形態改質剤としての両親媒性タンパク質 |
-
2010
- 2010-02-19 WO PCT/EP2010/052125 patent/WO2010097344A1/en active Application Filing
- 2010-02-19 KR KR1020117022071A patent/KR20110130440A/ko not_active Application Discontinuation
- 2010-02-19 US US13/202,112 patent/US8758730B2/en not_active Expired - Fee Related
- 2010-02-19 EP EP10704826.6A patent/EP2400988B1/en not_active Not-in-force
- 2010-02-19 CA CA2784516A patent/CA2784516C/en not_active Expired - Fee Related
- 2010-02-19 CN CN201080009474.2A patent/CN102333546B/zh not_active Expired - Fee Related
- 2010-02-19 JP JP2011551471A patent/JP5832302B2/ja not_active Expired - Fee Related
-
2012
- 2012-04-25 ZA ZA2012/03028A patent/ZA201203028B/en unknown
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2012518669A5 (ja) | ||
HRP20190689T1 (hr) | Muteini suznog lipokalina koji vežu il-4r alfa | |
JP2009268467A5 (ja) | ||
JP2013515057A5 (ja) | ||
JP2008521795A5 (ja) | ||
RU2019119609A (ru) | Пептиды, способные реактивировать мутанты р53 | |
RU2009128979A (ru) | Hla*1101-ограниченный пептид wt1 и содержащая его фармацевтическая композиция | |
JP2018504419A5 (ja) | ||
JP2018510622A5 (ja) | ||
US10647742B2 (en) | Method for synthesizing etelcalcetide | |
EA201170993A1 (ru) | Удлиненные рекомбинантные полипептиды и содержащие их композиции | |
JP2004529067A5 (ja) | ||
RU2016146198A (ru) | Терапевтические dll4-связывающие белки | |
JP2013527765A5 (ja) | ||
RU2017119773A (ru) | Пептидные антагонисты пептидных гормонов из семейства кальцитонина (cgrp) и их применение | |
EP2361930A3 (en) | Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases | |
JP2013543497A5 (ja) | ||
JP2005516072A5 (ja) | ||
JP2014506450A5 (ja) | ||
AR079114A1 (es) | Proteinas de enlace de antigenos anti-orai1 y usos de las mismas | |
ATE517118T1 (de) | Bis-met-histone | |
RU2015103816A (ru) | ПРОНИКАЮЩИЕ В КЛЕТКУ ПЕПТИДЫ, МИШЕНЬЮ КОТОРЫХ ЯВЛЯЕТСЯ eIF4E | |
WO2011038900A3 (en) | Peptide analogues of glucagon for diabetes therapy | |
WO2009024327A3 (en) | New proteins for use in human and animal staphylococcus infections | |
TW201629085A (zh) | 芋螺毒素(conotoxin)肽之修飾及用途 |