JP2012518598A5 - - Google Patents
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- Publication number
- JP2012518598A5 JP2012518598A5 JP2011535742A JP2011535742A JP2012518598A5 JP 2012518598 A5 JP2012518598 A5 JP 2012518598A5 JP 2011535742 A JP2011535742 A JP 2011535742A JP 2011535742 A JP2011535742 A JP 2011535742A JP 2012518598 A5 JP2012518598 A5 JP 2012518598A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- pyrimido
- anticancer
- alkyl group
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011535742A JP2012518598A (ja) | 2009-02-25 | 2010-02-18 | ピリミドピリミドインダゾール誘導体 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009042873 | 2009-02-25 | ||
| JP2009042873 | 2009-02-25 | ||
| PCT/JP2010/052910 WO2010098367A1 (en) | 2009-02-25 | 2010-02-18 | Pyrimidopyrimidoindazole derivative |
| JP2011535742A JP2012518598A (ja) | 2009-02-25 | 2010-02-18 | ピリミドピリミドインダゾール誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012518598A JP2012518598A (ja) | 2012-08-16 |
| JP2012518598A5 true JP2012518598A5 (enExample) | 2013-04-04 |
Family
ID=42665571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011535742A Pending JP2012518598A (ja) | 2009-02-25 | 2010-02-18 | ピリミドピリミドインダゾール誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8288396B2 (enExample) |
| EP (1) | EP2401281A4 (enExample) |
| JP (1) | JP2012518598A (enExample) |
| AU (1) | AU2010218781A1 (enExample) |
| CA (1) | CA2750716A1 (enExample) |
| WO (1) | WO2010098367A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2017127088A (ru) | 2010-11-16 | 2019-02-04 | Эррэй Биофарма Инк. | Комбинация ингибиторов чекпойнт-киназы 1 и ингибиторов киназы wee 1 |
| JP6313312B2 (ja) | 2012-10-02 | 2018-04-18 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 農薬としての複素環化合物 |
| FR3030513B1 (fr) * | 2014-12-19 | 2016-12-23 | Oreal | Derives de benzoxazine cationiques et utilisation en coloration capillaire. |
| DE102015012050A1 (de) * | 2015-09-15 | 2017-03-16 | Merck Patent Gmbh | Verbindungen als ASIC-Inhibitoren und deren Verwendungen |
| AU2018243667A1 (en) | 2017-03-31 | 2019-10-17 | Seagen Inc. | Combinations of Chk1- and Wee1 - inhibitors |
| AR111419A1 (es) | 2017-04-27 | 2019-07-10 | Novartis Ag | Compuestos fusionados de indazol piridona como antivirales |
| US11234977B2 (en) | 2017-12-20 | 2022-02-01 | Novartis Ag | Fused tricyclic pyrazolo-dihydropyrazinyl-pyridone compounds as antivirals |
| CN109912606B (zh) * | 2019-04-16 | 2021-05-04 | 新乡医学院 | 一种嘧啶并吲唑类化合物的合成方法 |
| CA3145344A1 (en) | 2019-06-28 | 2020-12-30 | Shanghai Pharmaceuticals Holding Co., Ltd. | Pyrazolopyrimidine compound, preparation method for same and applications thereof |
| CN112142748B (zh) | 2019-06-28 | 2023-07-04 | 上海医药集团股份有限公司 | 一种吡唑酮并嘧啶类化合物、其制备方法及应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| US5223608A (en) | 1987-08-28 | 1993-06-29 | Eli Lilly And Company | Process for and intermediates of 2',2'-difluoronucleosides |
| ATE186461T1 (de) | 1990-09-28 | 1999-11-15 | Smithkline Beecham Corp | Verfahren zur herstellung wasserlöslicher camptothecinanaloge, sowie die verbindungen 10- hydroxy-11-c(1-6)-alkoxycamptothecin |
| US5162532A (en) | 1990-12-20 | 1992-11-10 | North Carolina State University | Intermediates and method of making camptothecin and camptothecin analogs |
| US5243050A (en) | 1990-12-20 | 1993-09-07 | North Carolina State University | Alkylpyridone DE ring intermediates useful for the manufacture of camptothecin and camptothecin analogs |
| US5200524A (en) | 1990-12-20 | 1993-04-06 | North Carolina State University | Camptothecin intermediates and method of making same |
| US5191082A (en) | 1990-12-20 | 1993-03-02 | North Carolina State University | Camptothecin intermediate and method of making camptothecin intermediates |
| US5247089A (en) | 1990-12-20 | 1993-09-21 | North Carolina State University | Method of making intermediates useful for the manufacture of camptothecin and camptothecin analogs |
| ATE348110T1 (de) | 1992-10-28 | 2007-01-15 | Genentech Inc | Hvegf rezeptor als vegf antagonist |
| JP3025602B2 (ja) | 1993-05-21 | 2000-03-27 | デビオファーム エス．アー． | 光学的に高純度なシス−オキザラート（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ＩＩ）錯体の製造方法 |
| GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| EP0831880A4 (en) | 1995-06-07 | 2004-12-01 | Imclone Systems Inc | ANTIBODIES AND FRAGMENTS OF ANTIBODIES INHIBITING TUMOR GROWTH |
| JP3154399B2 (ja) | 1996-07-04 | 2001-04-09 | デビオファーム エス．アー． | 白金化合物の製造方法 |
| CN1138778C (zh) * | 1998-05-26 | 2004-02-18 | 沃尼尔·朗伯公司 | 用作细胞增殖抑制剂的二环嘧啶及二环3,4-二氢嘧啶化合物及用途 |
| US20040044012A1 (en) | 1998-05-26 | 2004-03-04 | Dobrusin Ellen Myra | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
| CA2483496A1 (en) | 2002-04-26 | 2003-11-06 | Warner-Lambert Company Llc | Inhibitors of checkpoint kinases (wee1 and chk1) |
| US7094798B1 (en) * | 2002-04-26 | 2006-08-22 | Pfizer Inc | Inhibitors of checkpoint kinases (Wee1 and Chk1) |
| US20050250836A1 (en) * | 2004-05-03 | 2005-11-10 | Pfizer Inc | Inhibitors of checkpoint kinases (Wee1 and Chk1) |
| AR060635A1 (es) * | 2006-04-27 | 2008-07-02 | Banyu Pharma Co Ltd | Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer |
| CA2689429C (en) * | 2007-06-15 | 2012-08-21 | Banyu Pharmaceutical Co., Ltd. | Bicycloaniline derivatives |
-
2010
- 2010-02-18 CA CA2750716A patent/CA2750716A1/en not_active Abandoned
- 2010-02-18 US US13/202,773 patent/US8288396B2/en not_active Expired - Fee Related
- 2010-02-18 WO PCT/JP2010/052910 patent/WO2010098367A1/en not_active Ceased
- 2010-02-18 AU AU2010218781A patent/AU2010218781A1/en not_active Abandoned
- 2010-02-18 EP EP10746246A patent/EP2401281A4/en not_active Withdrawn
- 2010-02-18 JP JP2011535742A patent/JP2012518598A/ja active Pending
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