JP2012518598A5 - - Google Patents
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- Publication number
- JP2012518598A5 JP2012518598A5 JP2011535742A JP2011535742A JP2012518598A5 JP 2012518598 A5 JP2012518598 A5 JP 2012518598A5 JP 2011535742 A JP2011535742 A JP 2011535742A JP 2011535742 A JP2011535742 A JP 2011535742A JP 2012518598 A5 JP2012518598 A5 JP 2012518598A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- pyrimido
- anticancer
- alkyl group
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011535742A JP2012518598A (ja) | 2009-02-25 | 2010-02-18 | ピリミドピリミドインダゾール誘導体 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009042873 | 2009-02-25 | ||
| JP2009042873 | 2009-02-25 | ||
| JP2011535742A JP2012518598A (ja) | 2009-02-25 | 2010-02-18 | ピリミドピリミドインダゾール誘導体 |
| PCT/JP2010/052910 WO2010098367A1 (en) | 2009-02-25 | 2010-02-18 | Pyrimidopyrimidoindazole derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012518598A JP2012518598A (ja) | 2012-08-16 |
| JP2012518598A5 true JP2012518598A5 (enExample) | 2013-04-04 |
Family
ID=42665571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011535742A Pending JP2012518598A (ja) | 2009-02-25 | 2010-02-18 | ピリミドピリミドインダゾール誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8288396B2 (enExample) |
| EP (1) | EP2401281A4 (enExample) |
| JP (1) | JP2012518598A (enExample) |
| AU (1) | AU2010218781A1 (enExample) |
| CA (1) | CA2750716A1 (enExample) |
| WO (1) | WO2010098367A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108721284A (zh) | 2010-11-16 | 2018-11-02 | 阵列生物制药公司 | 检测点激酶1抑制剂和wee1激酶抑制剂的组合 |
| DK2903440T3 (en) | 2012-10-02 | 2017-12-11 | Bayer Cropscience Ag | THETEROCYCLIC COMPOUNDS AS PESTICIDES |
| FR3030513B1 (fr) * | 2014-12-19 | 2016-12-23 | Oreal | Derives de benzoxazine cationiques et utilisation en coloration capillaire. |
| DE102015012050A1 (de) * | 2015-09-15 | 2017-03-16 | Merck Patent Gmbh | Verbindungen als ASIC-Inhibitoren und deren Verwendungen |
| KR20190130621A (ko) | 2017-03-31 | 2019-11-22 | 시애틀 지네틱스, 인크. | Chk1 저해제와 wee1 저해제의 조합물 |
| AR111419A1 (es) | 2017-04-27 | 2019-07-10 | Novartis Ag | Compuestos fusionados de indazol piridona como antivirales |
| CN111433210A (zh) | 2017-12-20 | 2020-07-17 | 诺华股份有限公司 | 作为抗病毒药的稠合三环吡唑并-二氢吡嗪基-吡啶酮化合物 |
| CN109912606B (zh) * | 2019-04-16 | 2021-05-04 | 新乡医学院 | 一种嘧啶并吲唑类化合物的合成方法 |
| BR112021026618A2 (pt) | 2019-06-28 | 2022-06-07 | Shanghai Pharmaceuticals Holding Co Ltd | Composto de pirazolpirimidina, método de preparação do mesmo e aplicações do mesmo |
| CN112142748B (zh) | 2019-06-28 | 2023-07-04 | 上海医药集团股份有限公司 | 一种吡唑酮并嘧啶类化合物、其制备方法及应用 |
| US12551584B1 (en) | 2020-12-07 | 2026-02-17 | Actinium Pharmaceuticals, Inc. | Lewis Y radioimmunotherapy for the treatment of cancer |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| US5223608A (en) | 1987-08-28 | 1993-06-29 | Eli Lilly And Company | Process for and intermediates of 2',2'-difluoronucleosides |
| DK0547165T3 (da) | 1990-09-28 | 2000-03-27 | Smithkline Beecham Corp | Fremgangsmåde til fremstilling af vandopløselige camptothecinanaloger såvel som forbindelserne 10-hydroxy-11-C(1-6)-alkoxyc |
| US5200524A (en) | 1990-12-20 | 1993-04-06 | North Carolina State University | Camptothecin intermediates and method of making same |
| US5191082A (en) | 1990-12-20 | 1993-03-02 | North Carolina State University | Camptothecin intermediate and method of making camptothecin intermediates |
| US5247089A (en) | 1990-12-20 | 1993-09-21 | North Carolina State University | Method of making intermediates useful for the manufacture of camptothecin and camptothecin analogs |
| US5243050A (en) | 1990-12-20 | 1993-09-07 | North Carolina State University | Alkylpyridone DE ring intermediates useful for the manufacture of camptothecin and camptothecin analogs |
| US5162532A (en) | 1990-12-20 | 1992-11-10 | North Carolina State University | Intermediates and method of making camptothecin and camptothecin analogs |
| KR100335584B1 (ko) | 1992-10-28 | 2002-11-29 | 제넨테크, 인코포레이티드 | 혈관내피세포성장인자에대한길항제 |
| JP3025602B2 (ja) | 1993-05-21 | 2000-03-27 | デビオファーム エス．アー． | 光学的に高純度なシス−オキザラート（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ＩＩ）錯体の製造方法 |
| GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| CA2222231A1 (en) | 1995-06-07 | 1996-12-19 | Imclone Systems Incorporated | Antibody and antibody fragments for inhibiting the growth of tumors |
| JP3154399B2 (ja) | 1996-07-04 | 2001-04-09 | デビオファーム エス．アー． | 白金化合物の製造方法 |
| US20040044012A1 (en) | 1998-05-26 | 2004-03-04 | Dobrusin Ellen Myra | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
| DE69939168D1 (de) * | 1998-05-26 | 2008-09-04 | Warner Lambert Co | Bicyclische pyrimidine und bicyclische 3,4-dihydropyrimidine als inhibitoren der zellvermehrung |
| US7094798B1 (en) | 2002-04-26 | 2006-08-22 | Pfizer Inc | Inhibitors of checkpoint kinases (Wee1 and Chk1) |
| AU2003224341A1 (en) | 2002-04-26 | 2003-11-10 | Warner-Lambert Company Llc | Inhibitors of checkpoint kinases (wee1 and chk1) |
| US20050250836A1 (en) * | 2004-05-03 | 2005-11-10 | Pfizer Inc | Inhibitors of checkpoint kinases (Wee1 and Chk1) |
| PE20080695A1 (es) | 2006-04-27 | 2008-06-28 | Banyu Pharma Co Ltd | Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel |
| PL2168966T3 (pl) | 2007-06-15 | 2017-06-30 | Msd K.K. | Pochodna bicykloaniliny |
-
2010
- 2010-02-18 WO PCT/JP2010/052910 patent/WO2010098367A1/en not_active Ceased
- 2010-02-18 AU AU2010218781A patent/AU2010218781A1/en not_active Abandoned
- 2010-02-18 US US13/202,773 patent/US8288396B2/en not_active Expired - Fee Related
- 2010-02-18 CA CA2750716A patent/CA2750716A1/en not_active Abandoned
- 2010-02-18 EP EP10746246A patent/EP2401281A4/en not_active Withdrawn
- 2010-02-18 JP JP2011535742A patent/JP2012518598A/ja active Pending
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