JP2012514007A5 - - Google Patents
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- Publication number
- JP2012514007A5 JP2012514007A5 JP2011543721A JP2011543721A JP2012514007A5 JP 2012514007 A5 JP2012514007 A5 JP 2012514007A5 JP 2011543721 A JP2011543721 A JP 2011543721A JP 2011543721 A JP2011543721 A JP 2011543721A JP 2012514007 A5 JP2012514007 A5 JP 2012514007A5
- Authority
- JP
- Japan
- Prior art keywords
- ethoxy
- pyridin
- radiopharmaceutical composition
- procedure
- vinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14188508P | 2008-12-31 | 2008-12-31 | |
| US61/141,885 | 2008-12-31 | ||
| PCT/US2009/069741 WO2010078370A1 (en) | 2008-12-31 | 2009-12-29 | Synthesis of 18f-radiolabeled styrylpyridines from tosylate precursors and stable pharmaceutical compositions thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012514007A JP2012514007A (ja) | 2012-06-21 |
| JP2012514007A5 true JP2012514007A5 (enExample) | 2013-06-06 |
| JP5717650B2 JP5717650B2 (ja) | 2015-05-13 |
Family
ID=42310197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543721A Active JP5717650B2 (ja) | 2008-12-31 | 2009-12-29 | トシラート前駆体からの１８ｆ−放射性標識スチリルピリジンおよびその安定性医薬組成物の合成 |
Country Status (35)
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2344877A4 (en) * | 2008-09-30 | 2014-09-10 | Univ Case Western Reserve | MOLECULAR SOLIDS FOR IMAGING MYELIN |
| MX2012014115A (es) * | 2010-06-04 | 2013-07-03 | Piramal Imaging Sa | Metodo para la produccion de ligandos beta amiloide marcados con 18f. |
| US20130209363A1 (en) | 2010-06-04 | 2013-08-15 | Piramal Imaging Sa | Method for production of f-18 labeled amyloid beta ligands |
| TWI504414B (zh) | 2010-06-04 | 2015-10-21 | Bayer Schering Pharma Ag | 生產Ｆ－１８標記之Ａβ配位體之方法 |
| WO2012145169A2 (en) * | 2011-04-21 | 2012-10-26 | The Regents Of The University Of California | Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles |
| MX344954B (es) * | 2011-06-21 | 2017-01-12 | Piramal Imaging Sa | Formulaciones de estilbeno fluorado adecuado para la formacion de imagenes pet. |
| JP2015501305A (ja) | 2011-10-19 | 2015-01-15 | ピラマル イメージング ソシエテ アノニム | Ｆ‐１８標識Ａβリガンドの改良された製造方法 |
| CN102432529B (zh) * | 2011-11-14 | 2014-03-26 | 江苏省原子医学研究所 | 一种苯乙烯基吡啶二硫二氮衍生物的制备方法 |
| JP2015507617A (ja) * | 2011-12-15 | 2015-03-12 | ジーイー・ヘルスケア・リミテッド | タウ病理のイメージングプローブとしての複素環式化合物 |
| CN102526765B (zh) * | 2011-12-31 | 2014-07-30 | 郑州泰基鸿诺药物科技有限公司 | 一种Aβ斑块显像剂及其制备方法 |
| CN103965105A (zh) * | 2013-01-29 | 2014-08-06 | 中山大学 | 苯乙烯基喹啉衍生物及其在治疗阿尔茨海默病症中的应用 |
| CN103645254B (zh) * | 2013-11-28 | 2015-01-07 | 江苏省原子医学研究所 | 一种Aβ斑块显像剂前体AV45的含量分析方法 |
| WO2017014599A1 (ko) * | 2015-07-22 | 2017-01-26 | 주식회사 씨코헬스케어 | [18f]플루오로-도파의 방사화학적 순도를 안정화시키는 조성물 및 이의 제조방법 |
| JP2018531978A (ja) * | 2015-11-13 | 2018-11-01 | イーライ リリー アンド カンパニー | タウイメージングのための新規化合物 |
| US10765763B2 (en) | 2016-03-09 | 2020-09-08 | Case Western Reserve University | Radioligands for myelin |
| CN107198780A (zh) * | 2016-03-18 | 2017-09-26 | 南京江原安迪科正电子研究发展有限公司 | 放射性药物组合物及其制备方法、应用 |
| CN106018575B (zh) * | 2016-05-05 | 2018-10-19 | 江苏省原子医学研究所 | 一种PET显像剂前体TsOP-(+)-DTBZ及其光学异构体的分离测定方法 |
| US10695450B2 (en) * | 2016-07-26 | 2020-06-30 | Laboratoires Cyclopharma | Synthesis of a radioactive agent composition |
| AU2017356943B2 (en) * | 2016-11-08 | 2024-10-31 | The Regents Of The University Of California | Methods for multi-dose synthesis of [F-18]FDDNP for clinical settings |
| TW201906818A (zh) * | 2017-05-31 | 2019-02-16 | 美商５１１製藥公司 | 新穎氘取代之正子發射斷層掃描（ｐｅｔ）顯影劑及其藥理應用 |
| CA3088232A1 (en) * | 2018-01-24 | 2019-08-01 | Ac Immune Sa | Diagnostic compositions for pet imaging, a method for manufacturing the diagnostic composition and its use in diagnostics |
| CN111499544B (zh) * | 2019-01-31 | 2022-12-02 | 中国医学科学院放射医学研究所 | 一种一锅法制备N-Boc-N-甲基-4-氨基苯乙烯的合成方法 |
| CN111499570B (zh) * | 2019-01-31 | 2023-05-16 | 中国医学科学院放射医学研究所 | 一种av-45中间体的合成方法 |
| CN113766952B (zh) * | 2019-03-29 | 2023-09-08 | 国立研究开发法人量子科学技术研究开发机构 | 放射性药品的制造方法及放射性药品 |
| CN115400232A (zh) * | 2021-05-26 | 2022-11-29 | 汉中汉核医疗科技有限公司 | 一种放射性药物合成方法 |
| CN115403434A (zh) * | 2021-05-26 | 2022-11-29 | 汉中汉核医疗科技有限公司 | 一种放射性药物的合成方法 |
| CN113582885B (zh) * | 2021-08-30 | 2023-04-21 | 南京克米斯璀新能源科技有限公司 | 一种烷基磺酸钠的生产方法 |
| CN114805190A (zh) * | 2022-06-08 | 2022-07-29 | 吉林大学第一医院 | 一种甲基苯胺类Aβ蛋白显像剂的双柱合成方法 |
| EP4619384A1 (en) * | 2022-11-14 | 2025-09-24 | Eli Lilly and Company | Polymorphic forms of florbetapir precursor av-105 |
| CN119080714A (zh) * | 2024-09-12 | 2024-12-06 | 四川大学 | 一种偶氮苯磺酸酯化合物及其制备方法和应用、放射性探针的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1711632A4 (en) * | 2004-01-19 | 2009-03-11 | Technion Res & Dev Foundation | DIAGNOSTIC TEST FOR PARKINSON |
| US7807135B2 (en) * | 2004-12-17 | 2010-10-05 | The Trustees Of The University Of Pennsylvania | Stilbene derivatives and their use for binding and imaging amyloid plaques |
| UA97802C2 (uk) * | 2006-03-30 | 2012-03-26 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Стирилпіридинові похідні і їх застосування для зв'язування і візуалізації амілоїдних бляшок |
-
2009
- 2009-12-29 CN CN200980153414.5A patent/CN102271716B/zh active Active
- 2009-12-29 CA CA2748705A patent/CA2748705C/en active Active
- 2009-12-29 JP JP2011543721A patent/JP5717650B2/ja active Active
- 2009-12-29 LT LTEP09837135.4T patent/LT2381967T/lt unknown
- 2009-12-29 UA UAA201109307A patent/UA105914C2/uk unknown
- 2009-12-29 WO PCT/US2009/069741 patent/WO2010078370A1/en not_active Ceased
- 2009-12-29 EP EP09837135.4A patent/EP2381967B1/en active Active
- 2009-12-29 SG SG2011048055A patent/SG172439A1/en unknown
- 2009-12-29 SI SI200931600A patent/SI2381967T1/sl unknown
- 2009-12-29 EA EA201170911A patent/EA023014B1/ru not_active IP Right Cessation
- 2009-12-29 RS RS20170117A patent/RS55674B1/sr unknown
- 2009-12-29 PT PT98371354T patent/PT2381967T/pt unknown
- 2009-12-29 MA MA34065A patent/MA33004B1/fr unknown
- 2009-12-29 MY MYPI2011003056A patent/MY162312A/en unknown
- 2009-12-29 MX MX2011007063A patent/MX2011007063A/es active IP Right Grant
- 2009-12-29 HR HRP20170453TT patent/HRP20170453T1/hr unknown
- 2009-12-29 AU AU2009335049A patent/AU2009335049B2/en active Active
- 2009-12-29 NZ NZ593848A patent/NZ593848A/xx unknown
- 2009-12-29 PL PL09837135T patent/PL2381967T3/pl unknown
- 2009-12-29 DK DK09837135.4T patent/DK2381967T3/en active
- 2009-12-29 ES ES09837135.4T patent/ES2620402T3/es active Active
- 2009-12-29 PE PE2011001294A patent/PE20120007A1/es not_active Application Discontinuation
- 2009-12-29 HU HUE09837135A patent/HUE033649T2/en unknown
- 2009-12-29 BR BRPI0923890-5A patent/BRPI0923890A2/pt active Search and Examination
- 2009-12-29 KR KR1020117017636A patent/KR20110119670A/ko not_active Ceased
- 2009-12-29 US US12/648,869 patent/US20100172836A1/en not_active Abandoned
-
2011
- 2011-06-20 IL IL213674A patent/IL213674A/en active IP Right Grant
- 2011-06-24 TN TN2011000318A patent/TN2011000318A1/fr unknown
- 2011-06-29 HN HN2011001810A patent/HN2011001810A/es unknown
- 2011-06-29 DO DO2011000210A patent/DOP2011000210A/es unknown
- 2011-06-29 ZA ZA2011/04824A patent/ZA201104824B/en unknown
- 2011-07-11 CO CO11086470A patent/CO6341578A2/es active IP Right Grant
- 2011-07-29 EC EC2011011242A patent/ECSP11011242A/es unknown
- 2011-07-29 CR CR20110410A patent/CR20110410A/es unknown
-
2017
- 2017-02-24 CY CY20171100253T patent/CY1118658T1/el unknown
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