JP2012514007A5 - - Google Patents

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Publication number
JP2012514007A5
JP2012514007A5 JP2011543721A JP2011543721A JP2012514007A5 JP 2012514007 A5 JP2012514007 A5 JP 2012514007A5 JP 2011543721 A JP2011543721 A JP 2011543721A JP 2011543721 A JP2011543721 A JP 2011543721A JP 2012514007 A5 JP2012514007 A5 JP 2012514007A5
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JP
Japan
Prior art keywords
ethoxy
pyridin
radiopharmaceutical composition
procedure
vinyl
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JP2011543721A
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English (en)
Japanese (ja)
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JP2012514007A (ja
JP5717650B2 (ja
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Priority claimed from PCT/US2009/069741 external-priority patent/WO2010078370A1/en
Publication of JP2012514007A publication Critical patent/JP2012514007A/ja
Publication of JP2012514007A5 publication Critical patent/JP2012514007A5/ja
Application granted granted Critical
Publication of JP5717650B2 publication Critical patent/JP5717650B2/ja
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JP2011543721A 2008-12-31 2009-12-29 トシラート前駆体からの１８ｆ−放射性標識スチリルピリジンおよびその安定性医薬組成物の合成 Active JP5717650B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14188508P 2008-12-31 2008-12-31
US61/141,885 2008-12-31
PCT/US2009/069741 WO2010078370A1 (en) 2008-12-31 2009-12-29 Synthesis of 18f-radiolabeled styrylpyridines from tosylate precursors and stable pharmaceutical compositions thereof

Publications (3)

Publication Number Publication Date
JP2012514007A JP2012514007A (ja) 2012-06-21
JP2012514007A5 true JP2012514007A5 (OSRAM) 2013-06-06
JP5717650B2 JP5717650B2 (ja) 2015-05-13

Family

ID=42310197

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011543721A Active JP5717650B2 (ja) 2008-12-31 2009-12-29 トシラート前駆体からの１８ｆ−放射性標識スチリルピリジンおよびその安定性医薬組成物の合成

Country Status (35)

Country Link
US (1) US20100172836A1 (OSRAM)
EP (1) EP2381967B1 (OSRAM)
JP (1) JP5717650B2 (OSRAM)
KR (1) KR20110119670A (OSRAM)
CN (1) CN102271716B (OSRAM)
AU (1) AU2009335049B2 (OSRAM)
BR (1) BRPI0923890A2 (OSRAM)
CA (1) CA2748705C (OSRAM)
CO (1) CO6341578A2 (OSRAM)
CR (1) CR20110410A (OSRAM)
CY (1) CY1118658T1 (OSRAM)
DK (1) DK2381967T3 (OSRAM)
DO (1) DOP2011000210A (OSRAM)
EA (1) EA023014B1 (OSRAM)
EC (1) ECSP11011242A (OSRAM)
ES (1) ES2620402T3 (OSRAM)
HN (1) HN2011001810A (OSRAM)
HR (1) HRP20170453T1 (OSRAM)
HU (1) HUE033649T2 (OSRAM)
IL (1) IL213674A (OSRAM)
LT (1) LT2381967T (OSRAM)
MA (1) MA33004B1 (OSRAM)
MX (1) MX2011007063A (OSRAM)
MY (1) MY162312A (OSRAM)
NZ (1) NZ593848A (OSRAM)
PE (1) PE20120007A1 (OSRAM)
PL (1) PL2381967T3 (OSRAM)
PT (1) PT2381967T (OSRAM)
RS (1) RS55674B1 (OSRAM)
SG (1) SG172439A1 (OSRAM)
SI (1) SI2381967T1 (OSRAM)
TN (1) TN2011000318A1 (OSRAM)
UA (1) UA105914C2 (OSRAM)
WO (1) WO2010078370A1 (OSRAM)
ZA (1) ZA201104824B (OSRAM)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2344877A4 (en) * 2008-09-30 2014-09-10 Univ Case Western Reserve MOLECULAR SOLIDS FOR IMAGING MYELIN
SG185785A1 (en) 2010-06-04 2013-01-30 Piramal Imaging Sa Method for production of f-18 labeled amyloid beta ligand
TWI504414B (zh) * 2010-06-04 2015-10-21 Bayer Schering Pharma Ag 生產Ｆ－１８標記之Ａβ配位體之方法
DK2579902T4 (da) 2010-06-04 2019-10-21 Life Molecular Imaging Sa Fremgangsmåde til fremstilling af f-18-mærkede amyloid-beta-ligander
KR20140012732A (ko) * 2011-04-21 2014-02-03 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 작용화된 자성 나노입자, 그리고 아밀로이드 침착물 및 신경섬유매듭의 영상화에서의 용도
CA2839961C (en) * 2011-06-21 2019-08-13 Piramal Imaging Sa Formulations of fluorinated stilbene suitable for pet imaging
WO2013057199A1 (en) 2011-10-19 2013-04-25 Piramal Imaging Sa IMPROVED METHOD FOR PRODUCTION OF F-18 LABELED Aß LIGANDS
CN102432529B (zh) * 2011-11-14 2014-03-26 江苏省原子医学研究所 一种苯乙烯基吡啶二硫二氮衍生物的制备方法
CN104136420A (zh) * 2011-12-15 2014-11-05 通用电气健康护理有限公司 作为tau病理学的成像探针的杂环化合物
CN102526765B (zh) * 2011-12-31 2014-07-30 郑州泰基鸿诺药物科技有限公司 一种Aβ斑块显像剂及其制备方法
CN103965105A (zh) * 2013-01-29 2014-08-06 中山大学 苯乙烯基喹啉衍生物及其在治疗阿尔茨海默病症中的应用
CN103645254B (zh) * 2013-11-28 2015-01-07 江苏省原子医学研究所 一种Aβ斑块显像剂前体AV45的含量分析方法
WO2017014599A1 (ko) * 2015-07-22 2017-01-26 주식회사 씨코헬스케어 [18f]플루오로-도파의 방사화학적 순도를 안정화시키는 조성물 및 이의 제조방법
US10301308B2 (en) * 2015-11-13 2019-05-28 Eli Lilly And Company Azetidine derivatives for tau imaging
US10765763B2 (en) 2016-03-09 2020-09-08 Case Western Reserve University Radioligands for myelin
CN107198780A (zh) * 2016-03-18 2017-09-26 南京江原安迪科正电子研究发展有限公司 放射性药物组合物及其制备方法、应用
CN106018575B (zh) * 2016-05-05 2018-10-19 江苏省原子医学研究所 一种PET显像剂前体TsOP-(+)-DTBZ及其光学异构体的分离测定方法
US10695450B2 (en) * 2016-07-26 2020-06-30 Laboratoires Cyclopharma Synthesis of a radioactive agent composition
WO2018089491A1 (en) * 2016-11-08 2018-05-17 The Regents Of The University Of California Methods for multi-dose synthesis of [f-18]fddnp for clinical settings
TW201906818A (zh) * 2017-05-31 2019-02-16 美商５１１製藥公司 新穎氘取代之正子發射斷層掃描（ｐｅｔ）顯影劑及其藥理應用
EP3743115A1 (en) * 2018-01-24 2020-12-02 AC Immune SA Diagnostic compositions for pet imaging, a method for manufacturing the diagnostic composition and its use in diagnostics
CN111499544B (zh) * 2019-01-31 2022-12-02 中国医学科学院放射医学研究所 一种一锅法制备N-Boc-N-甲基-4-氨基苯乙烯的合成方法
CN111499570B (zh) * 2019-01-31 2023-05-16 中国医学科学院放射医学研究所 一种av-45中间体的合成方法
JP7576334B2 (ja) * 2019-03-29 2024-10-31 国立研究開発法人量子科学技術研究開発機構 放射性医薬の製造方法及び放射性医薬
CN115400232A (zh) * 2021-05-26 2022-11-29 汉中汉核医疗科技有限公司 一种放射性药物合成方法
CN115403434A (zh) * 2021-05-26 2022-11-29 汉中汉核医疗科技有限公司 一种放射性药物的合成方法
CN113582885B (zh) * 2021-08-30 2023-04-21 南京克米斯璀新能源科技有限公司 一种烷基磺酸钠的生产方法
CN114805190A (zh) * 2022-06-08 2022-07-29 吉林大学第一医院 一种甲基苯胺类Aβ蛋白显像剂的双柱合成方法
JP2025535620A (ja) * 2022-11-14 2025-10-24 イーライ リリー アンド カンパニー フロルベタピル前駆体ａｖ－１０５の多形体
CN119080714A (zh) * 2024-09-12 2024-12-06 四川大学 一种偶氮苯磺酸酯化合物及其制备方法和应用、放射性探针的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005067391A2 (en) * 2004-01-19 2005-07-28 Technion Research & Development Foundation Ltd. Diagnostic test for parkinson's disease
SG194363A1 (en) * 2004-12-17 2013-11-29 Univ Pennsylvania Stilbene derivatives and their use for binding and imaging amyloid plaques
RS56171B1 (sr) * 2006-03-30 2017-11-30 Univ Pennsylvania Derivati stirilpiridina i njihova upotreba za vezivanje i imidžing amiloidnih plakova

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