JP2012118051A5 - - Google Patents
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- Publication number
- JP2012118051A5 JP2012118051A5 JP2011201542A JP2011201542A JP2012118051A5 JP 2012118051 A5 JP2012118051 A5 JP 2012118051A5 JP 2011201542 A JP2011201542 A JP 2011201542A JP 2011201542 A JP2011201542 A JP 2011201542A JP 2012118051 A5 JP2012118051 A5 JP 2012118051A5
- Authority
- JP
- Japan
- Prior art keywords
- sample
- procedure
- detection
- nucleic acid
- copper
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 27
- 238000001514 detection method Methods 0.000 claims description 26
- 150000007523 nucleic acids Chemical class 0.000 claims description 14
- 102000039446 nucleic acids Human genes 0.000 claims description 14
- 108020004707 nucleic acids Proteins 0.000 claims description 14
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 10
- 229910052802 copper Inorganic materials 0.000 claims description 10
- 239000010949 copper Substances 0.000 claims description 10
- 238000001228 spectrum Methods 0.000 claims description 8
- QAOWNCQODCNURD-UHFFFAOYSA-M hydrogensulfate Chemical compound OS([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-M 0.000 claims description 6
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 claims description 4
- 229940104302 cytosine Drugs 0.000 claims description 2
- 230000017858 demethylation Effects 0.000 claims description 2
- 238000010520 demethylation reaction Methods 0.000 claims description 2
- 230000001678 irradiating effect Effects 0.000 claims description 2
- 230000011987 methylation Effects 0.000 claims description 2
- 238000007069 methylation reaction Methods 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 230000003287 optical effect Effects 0.000 claims 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011201542A JP6003033B2 (ja) | 2010-11-11 | 2011-09-15 | 核酸の検出方法及びサンプルの光学観察方法並びに蛍光体 |
| PCT/JP2011/006163 WO2012063441A1 (ja) | 2010-11-11 | 2011-11-04 | 核酸の検出方法及びサンプルの光学観察方法並びに蛍光体 |
| CN2011800532046A CN103189509A (zh) | 2010-11-11 | 2011-11-04 | 核酸的检测方法、样品的光学观察方法及荧光物质 |
| EP17170998.3A EP3269810B1 (en) | 2010-11-11 | 2011-11-04 | Method of detecting nucleic acids, method of optically observing sample and fluorescent substance |
| EP11839814.8A EP2639304B1 (en) | 2010-11-11 | 2011-11-04 | Method for detecting a nucleic acid |
| US13/882,909 US9459213B2 (en) | 2010-11-11 | 2011-11-04 | Method of detecting nucleic acids, method of optically observing sample and fluorescent substance |
| US15/257,690 US10081830B2 (en) | 2010-11-11 | 2016-09-06 | Method of detecting nucleic acids, method of optically observing sample and fluorescent substance |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010252517 | 2010-11-11 | ||
| JP2010252517 | 2010-11-11 | ||
| JP2011201542A JP6003033B2 (ja) | 2010-11-11 | 2011-09-15 | 核酸の検出方法及びサンプルの光学観察方法並びに蛍光体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012118051A JP2012118051A (ja) | 2012-06-21 |
| JP2012118051A5 true JP2012118051A5 (enExample) | 2014-10-16 |
| JP6003033B2 JP6003033B2 (ja) | 2016-10-05 |
Family
ID=46050610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011201542A Active JP6003033B2 (ja) | 2010-11-11 | 2011-09-15 | 核酸の検出方法及びサンプルの光学観察方法並びに蛍光体 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9459213B2 (enExample) |
| EP (2) | EP3269810B1 (enExample) |
| JP (1) | JP6003033B2 (enExample) |
| CN (1) | CN103189509A (enExample) |
| WO (1) | WO2012063441A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6074911B2 (ja) | 2012-05-10 | 2017-02-08 | ソニー株式会社 | 核酸解析用マイクロチップ |
| JP6414238B2 (ja) * | 2017-01-12 | 2018-10-31 | ソニー株式会社 | 核酸解析用マイクロチップ |
| EP3840758A1 (en) * | 2018-08-21 | 2021-06-30 | Deep Genomics Incorporated | Therapeutic splice-switching oligonucleotides |
| CN111323396A (zh) * | 2018-12-14 | 2020-06-23 | 中国林业科学研究院资源昆虫研究所 | 一种测定紫胶色酸a含量的方法 |
| JP7717608B2 (ja) | 2019-05-31 | 2025-08-04 | フリーノム ホールディングス，インク． | メチル化核酸の高深度シーケンシングのための方法とシステム |
| JP2021097648A (ja) * | 2019-12-23 | 2021-07-01 | 横河電機株式会社 | 核酸配列計測装置及び核酸配列計測方法 |
| CN113252620B (zh) * | 2020-02-12 | 2025-09-05 | 青岛科技大学 | 一种可同时检测Hg2+和Ag+的方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8403691A (nl) | 1984-12-05 | 1986-07-01 | Philips Nv | Optische verbindingsinrichting. |
| US4969924A (en) | 1989-05-18 | 1990-11-13 | General Motors Corporation | Electro-optical connector plug |
| ES2089319T3 (es) | 1991-09-04 | 1996-10-01 | Furukawa Electric Co Ltd | Conector optico de nucleos multiples. |
| US20040086917A1 (en) * | 1995-09-27 | 2004-05-06 | Nanogen, Inc. | Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis |
| JP3975042B2 (ja) * | 1999-12-27 | 2007-09-12 | 富士フイルム株式会社 | 固相担体表面へのｄｎａ断片の固定方法及びｄｎａチップ |
| DE10019058A1 (de) | 2000-04-06 | 2001-12-20 | Epigenomics Ag | Detektion von Variationen des DNA-Methylierungsprofils |
| JP2003532898A (ja) * | 2000-05-05 | 2003-11-05 | バイエル アクチェンゲゼルシャフト | 生体標識としてのドープ処理されたナノ粒子 |
| MXPA03007147A (es) * | 2001-02-14 | 2003-11-18 | Univ Maryland | Tecnica para la disminucion de radiaciones. |
| US20030022150A1 (en) * | 2001-07-24 | 2003-01-30 | Sampson Jeffrey R. | Methods for detecting a target molecule |
| WO2003064701A2 (en) * | 2002-01-30 | 2003-08-07 | Epigenomics Ag | Method for the analysis of cytosine methylation patterns |
| DE10314579A1 (de) * | 2003-03-31 | 2004-10-14 | Carl Zeiss Jena Gmbh | Verfahren und Vorrichtung zur Sequenzanalyse von Nukleinsäuren |
| US7820385B2 (en) * | 2006-03-22 | 2010-10-26 | The United States Of America As Represented By The Department Of Health And Human Services, Centers For Disease Control And Prevention | Method for retaining methylation pattern in globally amplified DNA |
| JP2008157932A (ja) * | 2006-12-01 | 2008-07-10 | Ebara Corp | マイクロ流体デバイス、および、マイクロ流体デバイスの温度制御システム |
| CN101168773B (zh) * | 2007-10-16 | 2010-06-02 | 东南大学 | 一种基于荧光淬灭的核酸测序方法 |
| US8380028B2 (en) | 2009-05-18 | 2013-02-19 | Hitachi Cable, Ltd. | Composite cable |
| CN102043204B (zh) | 2009-10-20 | 2012-12-19 | 富士康(昆山)电脑接插件有限公司 | 连接器 |
| US8727637B2 (en) | 2010-03-19 | 2014-05-20 | Corning Incorporated | Fiber optic interface devices for electronic devices |
| US9046671B2 (en) | 2010-05-14 | 2015-06-02 | Sumitomo Electric Industries, Ltd. | Composite optical fiber cable and composite optical fiber cable assembly providing protection by flexure |
-
2011
- 2011-09-15 JP JP2011201542A patent/JP6003033B2/ja active Active
- 2011-11-04 US US13/882,909 patent/US9459213B2/en not_active Expired - Fee Related
- 2011-11-04 CN CN2011800532046A patent/CN103189509A/zh active Pending
- 2011-11-04 EP EP17170998.3A patent/EP3269810B1/en active Active
- 2011-11-04 EP EP11839814.8A patent/EP2639304B1/en not_active Not-in-force
- 2011-11-04 WO PCT/JP2011/006163 patent/WO2012063441A1/ja not_active Ceased
-
2016
- 2016-09-06 US US15/257,690 patent/US10081830B2/en active Active
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