JP2012010715A5 - - Google Patents
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- Publication number
- JP2012010715A5 JP2012010715A5 JP2011230342A JP2011230342A JP2012010715A5 JP 2012010715 A5 JP2012010715 A5 JP 2012010715A5 JP 2011230342 A JP2011230342 A JP 2011230342A JP 2011230342 A JP2011230342 A JP 2011230342A JP 2012010715 A5 JP2012010715 A5 JP 2012010715A5
- Authority
- JP
- Japan
- Prior art keywords
- inactivation
- deletion
- gene
- genetically modified
- coli strain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012217 deletion Methods 0.000 claims 5
- 230000037430 deletion Effects 0.000 claims 5
- 230000002779 inactivation Effects 0.000 claims 5
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 4
- 241000588724 Escherichia coli Species 0.000 claims 3
- 235000014655 lactic acid Nutrition 0.000 claims 2
- 239000004310 lactic acid Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 108010092060 Acetate kinase Proteins 0.000 claims 1
- 108010021809 Alcohol dehydrogenase Proteins 0.000 claims 1
- 108010012901 Succinate Dehydrogenase Proteins 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 108010008221 formate C-acetyltransferase Proteins 0.000 claims 1
- 108010083856 methylglyoxal synthase Proteins 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70688705P | 2005-08-10 | 2005-08-10 | |
| US60/706,887 | 2005-08-10 | ||
| US76157606P | 2006-01-24 | 2006-01-24 | |
| US60/761,576 | 2006-01-24 | ||
| US79961906P | 2006-05-11 | 2006-05-11 | |
| US60/799,619 | 2006-05-11 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006217580A Division JP4991205B2 (ja) | 2005-08-10 | 2006-08-09 | 乳酸生成に効果的な材料および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012010715A JP2012010715A (ja) | 2012-01-19 |
| JP2012010715A5 true JP2012010715A5 (enExample) | 2013-01-17 |
| JP5798441B2 JP5798441B2 (ja) | 2015-10-21 |
Family
ID=37488414
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006217580A Expired - Fee Related JP4991205B2 (ja) | 2005-08-10 | 2006-08-09 | 乳酸生成に効果的な材料および方法 |
| JP2011230342A Expired - Fee Related JP5798441B2 (ja) | 2005-08-10 | 2011-10-20 | 乳酸生成に効果的な材料および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006217580A Expired - Fee Related JP4991205B2 (ja) | 2005-08-10 | 2006-08-09 | 乳酸生成に効果的な材料および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7629162B2 (enExample) |
| EP (2) | EP2305826B1 (enExample) |
| JP (2) | JP4991205B2 (enExample) |
| CN (2) | CN1912107B (enExample) |
| BR (1) | BRPI0603072A (enExample) |
| DK (2) | DK1760156T3 (enExample) |
| ES (2) | ES2401339T3 (enExample) |
| PL (2) | PL1760156T3 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004044210A2 (en) * | 2002-11-06 | 2004-05-27 | University Of Florida | Materials and methods for the efficient production of acetate and other products |
| ES2619176T3 (es) * | 2003-09-30 | 2017-06-23 | Mitsui Chemicals, Inc. | Biocatalizador para producir ácido D-láctico |
| EP2305826B1 (en) * | 2005-08-10 | 2016-03-30 | University of Florida Research Foundation, Inc. | Materials and methods for efficient lactic acid production |
| EP2570481B1 (en) * | 2007-03-20 | 2014-11-26 | University of Florida Research Foundation, Inc. | Materials and methods for efficient succinate and malate production |
| US20090082600A1 (en) * | 2007-06-06 | 2009-03-26 | Shengde Zhou | Native homoethanol Pathway for ethanol production in E. coli |
| US8129154B2 (en) * | 2008-06-17 | 2012-03-06 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
| EP2336295B1 (en) | 2008-09-16 | 2018-01-24 | Mitsui Chemicals, Inc. | Method for producing lactic acid from plant-derived raw material, and lactic-acid-producing bacterium |
| WO2010059616A2 (en) * | 2008-11-18 | 2010-05-27 | University Of Florida Research Foundation, Inc. | Biocatalysts and methods for conversion of hemicellulose hydrolsates to biobased products |
| US8715972B2 (en) * | 2009-02-18 | 2014-05-06 | Bio-Energy Corporation | Homolactic fermentation from pentose |
| KR20120025450A (ko) | 2009-04-02 | 2012-03-15 | 유니버시티 오브 플로리다 리서치 파운데이션, 인크. | 석시네이트 생성을 위한 경로의 엔지니어링 |
| EP2446019B1 (en) * | 2009-06-23 | 2015-03-25 | BP Corporation North America, Inc. | Recombinant ethanologenic bacteria |
| JP5913099B2 (ja) | 2009-07-30 | 2016-04-27 | メタボリック エクスプローラー | 発酵による生化学物質生産のための変異型メチルグリオキサールシンターゼ（ｍｇｓ） |
| KR20120103645A (ko) | 2009-11-18 | 2012-09-19 | 미리안트 코포레이션 | 유기산들을 생산하는 대장균의 대사적 진화 |
| US10017793B2 (en) | 2009-11-18 | 2018-07-10 | Myriant Corporation | Metabolic evolution of Escherichia coli strains that produce organic acids |
| WO2011063055A2 (en) | 2009-11-18 | 2011-05-26 | Myriant Technologies Llc | Engineering microbes for efficient production of chemicals |
| WO2011063157A2 (en) | 2009-11-18 | 2011-05-26 | Myriant Technologies Llc | Organic acid production in microorganisms by combined reductive and oxidative tricarboxylic acid cycle pathways |
| MX2013005654A (es) | 2010-11-22 | 2013-07-17 | Novozymes Inc | Composiciones y metodos para la produccion de acido 3-hidroxipropionico. |
| US9347077B2 (en) | 2011-07-08 | 2016-05-24 | University Of Florida Research Foundation, Incorporated | Over-expression of a putative oxidoreductase (UcpA) for increasing furfural or 5-hydroxymethylfurfural tolerance |
| BR112014001371B1 (pt) | 2011-07-22 | 2021-06-01 | Myriant Corporation | Bactéria escherichia coli geneticamente modificada e método para produção de ácido succínico |
| JPWO2014017469A1 (ja) * | 2012-07-23 | 2016-07-11 | 三井化学株式会社 | Ｄ−乳酸の生産方法およびポリマーの生産方法 |
| JP2015536669A (ja) | 2012-11-30 | 2015-12-24 | ノボザイムス，インコーポレイティド | 組換え酵母による３−ヒドロキシプロピオン酸の生産 |
| KR20140075044A (ko) | 2012-12-07 | 2014-06-19 | 삼성전자주식회사 | 불포화 카르복실산의 제조방법 |
| CN104278003B (zh) * | 2013-07-12 | 2018-12-18 | 中国科学院天津工业生物技术研究所 | 生产d-乳酸的重组大肠杆菌及其应用 |
| DK3027733T3 (en) | 2013-07-31 | 2018-12-10 | Novozymes As | Preparation of 3-Hydroxypropionic Acid in Recombinant Yeast Expressing an Insect Aspartate-1 Decarboxylase |
| EP2977471A1 (en) * | 2014-07-23 | 2016-01-27 | PURAC Biochem BV | Genetic modification of (S)-lactic acid producing thermophilic bacteria |
| AU2015294136C9 (en) * | 2014-07-23 | 2019-05-02 | Purac Biochem Bv | Genetically modified (R)-lactic acid producing thermophilic bacteria |
| KR102581464B1 (ko) | 2015-05-28 | 2023-09-21 | 삼성전자주식회사 | 락테이트 데히드로게나제 변이체를 스크리닝하는 방법, 락테이트 데히드로게나제 변이체, 상기 변이체를 포함하는 폴리뉴클레오티드, 벡터, 미생물, 및 상기 미생물을 이용하여 락테이트를 생산하는 방법 |
| JP2017121184A (ja) * | 2016-01-04 | 2017-07-13 | 花王株式会社 | 変異リゾプス属菌 |
| US11447802B2 (en) | 2018-02-16 | 2022-09-20 | Ptt Global Chemical Public Company Limited | Microorganisms and processes for lactic acid production |
| CN109280652A (zh) * | 2018-09-13 | 2019-01-29 | 四川自豪时代药业有限公司 | 一种外源高表达乳酸脱氢酶突变体的高密度发酵方法 |
| CN109321590B (zh) * | 2018-10-19 | 2022-06-21 | 北京化工大学 | 利用乙酸生产l-乳酸的基因工程菌及其构建方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5821093A (en) * | 1988-08-31 | 1998-10-13 | University Of Florida Research Foundation, Inc. | Recombinant cells that highly express chromosomally-integrated heterologous genes |
| US4963486A (en) | 1989-04-21 | 1990-10-16 | Cornell Research Foundation, Inc. | Direct fermentation of corn to L(+)-lactic acid by Rhizopus oryzae |
| CN1156180A (zh) * | 1995-09-05 | 1997-08-06 | 底古萨股份公司 | 用大肠杆菌生产色氨酸 |
| IT1294728B1 (it) | 1997-09-12 | 1999-04-12 | Biopolo S C A R L | Ceppi di lievito per la riproduzione di acido lattico |
| US6849444B2 (en) | 2001-04-26 | 2005-02-01 | Archer Daniels Midland Company | Strains of Rhizopus oryzae and uses thereof |
| US7232664B2 (en) | 2002-05-30 | 2007-06-19 | Natureworks Llc | Fermentation process using specific oxygen uptake rates as a process control |
| US7300787B2 (en) | 2002-07-05 | 2007-11-27 | Archer-Daniels-Midland Company | Lactobacillus strains and use thereof in fermentation for L-lactic acid production |
| WO2004044210A2 (en) * | 2002-11-06 | 2004-05-27 | University Of Florida | Materials and methods for the efficient production of acetate and other products |
| US20050112737A1 (en) | 2003-11-20 | 2005-05-26 | A. E. Staley Manufacturing Co. | Lactic acid producing yeast |
| EP2305826B1 (en) * | 2005-08-10 | 2016-03-30 | University of Florida Research Foundation, Inc. | Materials and methods for efficient lactic acid production |
-
2006
- 2006-08-02 EP EP10186896.6A patent/EP2305826B1/en not_active Not-in-force
- 2006-08-02 EP EP06118331A patent/EP1760156B1/en not_active Not-in-force
- 2006-08-02 PL PL06118331T patent/PL1760156T3/pl unknown
- 2006-08-02 PL PL10186896.6T patent/PL2305826T3/pl unknown
- 2006-08-02 DK DK06118331.5T patent/DK1760156T3/da active
- 2006-08-02 DK DK10186896.6T patent/DK2305826T3/en active
- 2006-08-02 ES ES06118331T patent/ES2401339T3/es active Active
- 2006-08-02 ES ES10186896.6T patent/ES2573980T3/es active Active
- 2006-08-08 US US11/501,137 patent/US7629162B2/en not_active Expired - Fee Related
- 2006-08-09 BR BRPI0603072-6A patent/BRPI0603072A/pt not_active Application Discontinuation
- 2006-08-09 JP JP2006217580A patent/JP4991205B2/ja not_active Expired - Fee Related
- 2006-08-10 CN CN2006101093329A patent/CN1912107B/zh not_active Expired - Fee Related
- 2006-08-10 CN CN201310012065.3A patent/CN103396974B/zh not_active Expired - Fee Related
-
2009
- 2009-12-07 US US12/632,041 patent/US8426191B2/en not_active Expired - Fee Related
-
2011
- 2011-10-20 JP JP2011230342A patent/JP5798441B2/ja not_active Expired - Fee Related
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