JP4991205B2 - 乳酸生成に効果的な材料および方法 - Google Patents

乳酸生成に効果的な材料および方法 Download PDF

Info

Publication number
JP4991205B2
JP4991205B2 JP2006217580A JP2006217580A JP4991205B2 JP 4991205 B2 JP4991205 B2 JP 4991205B2 JP 2006217580 A JP2006217580 A JP 2006217580A JP 2006217580 A JP2006217580 A JP 2006217580A JP 4991205 B2 JP4991205 B2 JP 4991205B2
Authority
JP
Japan
Prior art keywords
lactate
strain
lactic acid
genetically modified
nrrl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2006217580A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007049993A (ja
Inventor
シェンド チョウ
ロニー オニール イングラム
キールナサム ティー． シャンムガム
ロレイン ピー． ヨマノ
タミー ビー． グラバー
ジョナサン シー． ムーア
Original Assignee
ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド filed Critical ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド
Publication of JP2007049993A publication Critical patent/JP2007049993A/ja
Application granted granted Critical
Publication of JP4991205B2 publication Critical patent/JP4991205B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2006217580A 2005-08-10 2006-08-09 乳酸生成に効果的な材料および方法 Expired - Fee Related JP4991205B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US70688705P 2005-08-10 2005-08-10
US60/706,887 2005-08-10
US76157606P 2006-01-24 2006-01-24
US60/761,576 2006-01-24
US79961906P 2006-05-11 2006-05-11
US60/799,619 2006-05-11

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011230342A Division JP5798441B2 (ja) 2005-08-10 2011-10-20 乳酸生成に効果的な材料および方法

Publications (2)

Publication Number Publication Date
JP2007049993A JP2007049993A (ja) 2007-03-01
JP4991205B2 true JP4991205B2 (ja) 2012-08-01

Family

ID=37488414

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006217580A Expired - Fee Related JP4991205B2 (ja) 2005-08-10 2006-08-09 乳酸生成に効果的な材料および方法
JP2011230342A Expired - Fee Related JP5798441B2 (ja) 2005-08-10 2011-10-20 乳酸生成に効果的な材料および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011230342A Expired - Fee Related JP5798441B2 (ja) 2005-08-10 2011-10-20 乳酸生成に効果的な材料および方法

Country Status (8)

Country Link
US (2) US7629162B2 (enExample)
EP (2) EP2305826B1 (enExample)
JP (2) JP4991205B2 (enExample)
CN (2) CN103396974B (enExample)
BR (1) BRPI0603072A (enExample)
DK (2) DK1760156T3 (enExample)
ES (2) ES2573980T3 (enExample)
PL (2) PL2305826T3 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003287625A1 (en) 2002-11-06 2004-06-03 University Of Florida Materials and methods for the efficient production of acetate and other products
BRPI0414673B1 (pt) * 2003-09-30 2019-12-17 Mitsui Chemicals Inc escherichia coli recombinante, bem como método para a produção de ácido d-láctico
DK1760156T3 (da) * 2005-08-10 2013-03-18 Univ Florida Materialer og fremgangsmåder til effektiv mælkesyrefremstilling
EP2121915B1 (en) * 2007-03-20 2012-08-08 University of Florida Research Foundation, Inc. Materials and methods for efficient succinate and malate production
US20090082600A1 (en) * 2007-06-06 2009-03-26 Shengde Zhou Native homoethanol Pathway for ethanol production in E. coli
US8129154B2 (en) 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
CN102333859B (zh) 2008-09-16 2015-04-22 三井化学株式会社 由来自植物的原料生产乳酸的方法及生产乳酸的细菌
WO2010059616A2 (en) * 2008-11-18 2010-05-27 University Of Florida Research Foundation, Inc. Biocatalysts and methods for conversion of hemicellulose hydrolsates to biobased products
MY158573A (en) * 2009-02-18 2016-10-14 Kansai Chem Eng Homolactic fermentation from pentose
KR20120025450A (ko) 2009-04-02 2012-03-15 유니버시티 오브 플로리다 리서치 파운데이션, 인크. 석시네이트 생성을 위한 경로의 엔지니어링
US9169485B2 (en) 2009-06-23 2015-10-27 Bp Corporation North America Inc. Recombinant ethanologenic bacteria comprising a urease gene
JP5913099B2 (ja) 2009-07-30 2016-04-27 メタボリック エクスプローラー 発酵による生化学物質生産のための変異型メチルグリオキサールシンターゼ（ｍｇｓ）
US10017793B2 (en) 2009-11-18 2018-07-10 Myriant Corporation Metabolic evolution of Escherichia coli strains that produce organic acids
WO2011063157A2 (en) 2009-11-18 2011-05-26 Myriant Technologies Llc Organic acid production in microorganisms by combined reductive and oxidative tricarboxylic acid cycle pathways
MX2012005751A (es) 2009-11-18 2012-06-19 Myriant Corp Evolucion metabolica de cepas de escherichia coli que producen acidos organicos.
BR112012011990A2 (pt) 2009-11-18 2015-09-29 Myriant Corp microrganismo que não ocorre naturalmente e método para produzir ácido succínico
MX2013005654A (es) 2010-11-22 2013-07-17 Novozymes Inc Composiciones y metodos para la produccion de acido 3-hidroxipropionico.
WO2013009679A2 (en) 2011-07-08 2013-01-17 University Of Florida Research Foundation, Inc. Over-expression of a putative oxidoreductase (ucpa) for increasing furfural or 5-hydroxymethylfurfural tolerance
US10041094B2 (en) 2011-07-22 2018-08-07 Myriant Corporation Fermentation of glycerol to organic acids
JPWO2014017469A1 (ja) * 2012-07-23 2016-07-11 三井化学株式会社 Ｄ−乳酸の生産方法およびポリマーの生産方法
JP2015536669A (ja) 2012-11-30 2015-12-24 ノボザイムス，インコーポレイティド 組換え酵母による３−ヒドロキシプロピオン酸の生産
KR20140075044A (ko) 2012-12-07 2014-06-19 삼성전자주식회사 불포화 카르복실산의 제조방법
CN104278003B (zh) * 2013-07-12 2018-12-18 中国科学院天津工业生物技术研究所 生产d-乳酸的重组大肠杆菌及其应用
US9845484B2 (en) 2013-07-31 2017-12-19 Novozymes A/S 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase
CA2955717C (en) * 2014-07-23 2020-09-22 Purac Biochem Bv Genetically modified (r)-lactic acid producing thermophilic bacteria
EP2977471A1 (en) 2014-07-23 2016-01-27 PURAC Biochem BV Genetic modification of (S)-lactic acid producing thermophilic bacteria
KR102581464B1 (ko) 2015-05-28 2023-09-21 삼성전자주식회사 락테이트 데히드로게나제 변이체를 스크리닝하는 방법, 락테이트 데히드로게나제 변이체, 상기 변이체를 포함하는 폴리뉴클레오티드, 벡터, 미생물, 및 상기 미생물을 이용하여 락테이트를 생산하는 방법
JP2017121184A (ja) * 2016-01-04 2017-07-13 花王株式会社 変異リゾプス属菌
US11447802B2 (en) 2018-02-16 2022-09-20 Ptt Global Chemical Public Company Limited Microorganisms and processes for lactic acid production
CN109280652A (zh) * 2018-09-13 2019-01-29 四川自豪时代药业有限公司 一种外源高表达乳酸脱氢酶突变体的高密度发酵方法
CN109321590B (zh) * 2018-10-19 2022-06-21 北京化工大学 利用乙酸生产l-乳酸的基因工程菌及其构建方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821093A (en) * 1988-08-31 1998-10-13 University Of Florida Research Foundation, Inc. Recombinant cells that highly express chromosomally-integrated heterologous genes
US4963486A (en) 1989-04-21 1990-10-16 Cornell Research Foundation, Inc. Direct fermentation of corn to L(+)-lactic acid by Rhizopus oryzae
CN1156180A (zh) * 1995-09-05 1997-08-06 底古萨股份公司 用大肠杆菌生产色氨酸
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US6849444B2 (en) 2001-04-26 2005-02-01 Archer Daniels Midland Company Strains of Rhizopus oryzae and uses thereof
WO2003102200A2 (en) 2002-05-30 2003-12-11 Cargill Dow Llc Fermentation process using specific oxygen uptake rates as a process control
US7300787B2 (en) 2002-07-05 2007-11-27 Archer-Daniels-Midland Company Lactobacillus strains and use thereof in fermentation for L-lactic acid production
AU2003287625A1 (en) * 2002-11-06 2004-06-03 University Of Florida Materials and methods for the efficient production of acetate and other products
US20050112737A1 (en) 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
DK1760156T3 (da) * 2005-08-10 2013-03-18 Univ Florida Materialer og fremgangsmåder til effektiv mælkesyrefremstilling

Also Published As

Publication number Publication date
US7629162B2 (en) 2009-12-08
JP2012010715A (ja) 2012-01-19
US20070037265A1 (en) 2007-02-15
ES2573980T3 (es) 2016-06-13
CN1912107A (zh) 2007-02-14
EP2305826B1 (en) 2016-03-30
PL1760156T3 (pl) 2013-05-31
EP1760156A2 (en) 2007-03-07
EP1760156A9 (en) 2007-04-25
JP5798441B2 (ja) 2015-10-21
DK1760156T3 (da) 2013-03-18
US8426191B2 (en) 2013-04-23
PL2305826T3 (pl) 2016-10-31
CN103396974B (zh) 2016-12-07
BRPI0603072A (pt) 2007-03-27
ES2401339T3 (es) 2013-04-18
CN1912107B (zh) 2013-03-13
CN103396974A (zh) 2013-11-20
DK2305826T3 (en) 2016-06-27
EP1760156A3 (en) 2007-04-04
US20100203602A1 (en) 2010-08-12
EP2305826A1 (en) 2011-04-06
EP1760156B1 (en) 2012-12-19
JP2007049993A (ja) 2007-03-01

Similar Documents

Publication Publication Date Title
JP5798441B2 (ja) 乳酸生成に効果的な材料および方法
US8691539B2 (en) Materials and methods for efficient succinate and malate production
Jantama et al. Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C that produce succinate and malate
Zhang et al. Production of L-alanine by metabolically engineered Escherichia coli
WO2008119009A2 (en) Materials and methods for efficient alanine production
CN102618478A (zh) 一株产d-乳酸动态调控重组菌及用其制备d-乳酸的方法
HK1137485B (en) Materials and methods for efficient succinate and malate production
HK1211318B (en) Materials and methods for efficient succinate and malate production

Legal Events

Date Code Title Description
A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20061208

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080924

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110425

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110721

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110726

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20111020

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120105

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120404

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20120423

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20120507

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20150511

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees