JP2011529571A5 - - Google Patents
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- JP2011529571A5 JP2011529571A5 JP2011520526A JP2011520526A JP2011529571A5 JP 2011529571 A5 JP2011529571 A5 JP 2011529571A5 JP 2011520526 A JP2011520526 A JP 2011520526A JP 2011520526 A JP2011520526 A JP 2011520526A JP 2011529571 A5 JP2011529571 A5 JP 2011529571A5
- Authority
- JP
- Japan
- Prior art keywords
- amount
- biological sample
- nds
- mci
- normal control
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8515408P | 2008-07-31 | 2008-07-31 | |
| US61/085,154 | 2008-07-31 | ||
| PCT/EP2009/059951 WO2010012828A2 (en) | 2008-07-31 | 2009-07-31 | Glutaminyl cyclase as a diagnostic / prognostic indicator for neurodegenerative diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011529571A JP2011529571A (ja) | 2011-12-08 |
| JP2011529571A5 true JP2011529571A5 (OSRAM) | 2012-09-20 |
| JP5677297B2 JP5677297B2 (ja) | 2015-02-25 |
Family
ID=41256108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011520526A Active JP5677297B2 (ja) | 2008-07-31 | 2009-07-31 | 神経変性疾患の診断／予後判定の指標としてのグルタミニルシクラーゼ |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20100028918A1 (OSRAM) |
| EP (1) | EP2329274B1 (OSRAM) |
| JP (1) | JP5677297B2 (OSRAM) |
| KR (1) | KR101682728B1 (OSRAM) |
| CN (2) | CN103983787A (OSRAM) |
| AU (1) | AU2009275869B2 (OSRAM) |
| BR (1) | BRPI0916601B1 (OSRAM) |
| CA (1) | CA2731933A1 (OSRAM) |
| EA (1) | EA025107B1 (OSRAM) |
| IL (1) | IL210266A (OSRAM) |
| MX (1) | MX2011001093A (OSRAM) |
| NZ (1) | NZ590658A (OSRAM) |
| SG (1) | SG193148A1 (OSRAM) |
| WO (1) | WO2010012828A2 (OSRAM) |
| ZA (1) | ZA201100177B (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013519891A (ja) * | 2010-02-18 | 2013-05-30 | プロビオドルグ エージー | ピログルタミン酸修飾ｍｃｐ−１を決定することにより炎症性疾患を診断する方法及びグルタミニルシクラーゼの阻害剤のスクリーニング方法 |
| JP2014515364A (ja) | 2011-05-27 | 2014-06-30 | プロビオドルグ エージー | 放射能標識グルタミニルシクラーゼ阻害剤 |
| US20170363645A1 (en) | 2014-12-19 | 2017-12-21 | Probiodrug Ag | Novel Method for the Detection of pGlu-Abeta Peptides |
| CN104946680A (zh) * | 2015-06-11 | 2015-09-30 | 深圳大学 | 用于表达qc的重组载体及其制备方法、引物、基因工程菌 |
| KR102362919B1 (ko) * | 2016-07-08 | 2022-02-16 | 아지노모토 가부시키가이샤 | 경도 인지 장해 또는 알츠하이머형 인지증의 평가 방법 |
| KR102858457B1 (ko) * | 2023-06-07 | 2025-09-11 | 계명대학교 산학협력단 | Ccl8 단백질 또는 이를 코딩하는 유전자를 유효성분으로 포함하는 퇴행성 뇌질환 진단용 바이오마커 조성물 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4374316B2 (ja) * | 1993-01-25 | 2009-12-02 | 武田薬品工業株式会社 | β−アミロイドまたはその誘導体に対する抗体およびその用途 |
| JP3590468B2 (ja) * | 1996-01-22 | 2004-11-17 | 財団法人 東京都医学研究機構 | アルツハイマー病診断薬 |
| EP1523499A2 (en) * | 2002-07-24 | 2005-04-20 | Innogenetics N.V. | Fragments of beta-amyloid as targets for vaccination against alzheimer disease |
| US7732162B2 (en) * | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
| MXPA05011861A (es) * | 2003-05-05 | 2006-02-17 | Probiodrug Ag | Uso de efectores de ciclasas de glutamato y glutaminil. |
| CA2542419C (en) * | 2003-10-15 | 2013-06-04 | Probiodrug Ag | Use of glutamyl cyclase inhibitors in the treatment of familial british dementia and familial danish dementia |
| US20060094064A1 (en) * | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
| KR101099206B1 (ko) * | 2004-02-05 | 2011-12-27 | 프로비오드룩 아게 | 신규한 글루타미닐 시클라제 저해제 |
| WO2006120104A1 (en) * | 2005-04-11 | 2006-11-16 | Probiodrug Ag | Inhibitors of prolyl endopeptidase |
| ATE523788T1 (de) * | 2006-06-08 | 2011-09-15 | Fu Berlin | ASSAY ZUR DIAGNOSE VON ALZHEIMER BASIEREND AUF DER BESTIMMUNG DES VERHÄLTNISSES VON SEKRETASE-Aß-SPALTPRODUKTEN |
| JP2010504088A (ja) * | 2006-09-21 | 2010-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼに関連した新規遺伝子 |
| WO2008087197A1 (en) * | 2007-01-19 | 2008-07-24 | Probiodrug Ag | In vivo screening models for treatment of alzheimer's disease and other qpct-related disorders |
-
2009
- 2009-07-31 JP JP2011520526A patent/JP5677297B2/ja active Active
- 2009-07-31 KR KR1020117002132A patent/KR101682728B1/ko active Active
- 2009-07-31 CN CN201410221835.XA patent/CN103983787A/zh active Pending
- 2009-07-31 CN CN200980130500.4A patent/CN102112880B/zh active Active
- 2009-07-31 BR BRPI0916601-7A patent/BRPI0916601B1/pt active IP Right Grant
- 2009-07-31 AU AU2009275869A patent/AU2009275869B2/en active Active
- 2009-07-31 WO PCT/EP2009/059951 patent/WO2010012828A2/en not_active Ceased
- 2009-07-31 MX MX2011001093A patent/MX2011001093A/es active IP Right Grant
- 2009-07-31 NZ NZ590658A patent/NZ590658A/en unknown
- 2009-07-31 EA EA201100253A patent/EA025107B1/ru not_active IP Right Cessation
- 2009-07-31 US US12/533,099 patent/US20100028918A1/en not_active Abandoned
- 2009-07-31 CA CA2731933A patent/CA2731933A1/en not_active Abandoned
- 2009-07-31 EP EP09781358.8A patent/EP2329274B1/en active Active
- 2009-07-31 SG SG2013056478A patent/SG193148A1/en unknown
-
2010
- 2010-12-26 IL IL210266A patent/IL210266A/en active IP Right Grant
-
2011
- 2011-01-06 ZA ZA2011/00177A patent/ZA201100177B/en unknown
-
2015
- 2015-03-12 US US14/645,821 patent/US20150247180A1/en not_active Abandoned
-
2016
- 2016-12-14 US US15/378,328 patent/US20170097365A1/en not_active Abandoned
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