ATE523788T1 - ASSAY ZUR DIAGNOSE VON ALZHEIMER BASIEREND AUF DER BESTIMMUNG DES VERHÄLTNISSES VON SEKRETASE-Aß-SPALTPRODUKTEN - Google Patents
ASSAY ZUR DIAGNOSE VON ALZHEIMER BASIEREND AUF DER BESTIMMUNG DES VERHÄLTNISSES VON SEKRETASE-Aß-SPALTPRODUKTENInfo
- Publication number
- ATE523788T1 ATE523788T1 AT06011829T AT06011829T ATE523788T1 AT E523788 T1 ATE523788 T1 AT E523788T1 AT 06011829 T AT06011829 T AT 06011829T AT 06011829 T AT06011829 T AT 06011829T AT E523788 T1 ATE523788 T1 AT E523788T1
- Authority
- AT
- Austria
- Prior art keywords
- ratio
- alzheimer
- diagnosis
- determination
- secretase
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medical Treatment And Welfare Office Work (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06011829A EP1865326B1 (de) | 2006-06-08 | 2006-06-08 | Assay zur Diagnose von Alzheimer basierend auf der Bestimmung des Verhältnisses von Sekretase-Aß-Spaltprodukten |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE523788T1 true ATE523788T1 (de) | 2011-09-15 |
Family
ID=36922150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06011829T ATE523788T1 (de) | 2006-06-08 | 2006-06-08 | ASSAY ZUR DIAGNOSE VON ALZHEIMER BASIEREND AUF DER BESTIMMUNG DES VERHÄLTNISSES VON SEKRETASE-Aß-SPALTPRODUKTEN |
Country Status (6)
Country | Link |
---|---|
US (1) | US20100221759A1 (de) |
EP (2) | EP1865326B1 (de) |
CN (1) | CN101460853A (de) |
AT (1) | ATE523788T1 (de) |
ES (1) | ES2373048T3 (de) |
WO (1) | WO2007140843A2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003063693A2 (en) * | 2002-01-31 | 2003-08-07 | Expressive Constructs, Inc. | Method for detecting microorganisms |
CA2669848A1 (en) * | 2006-11-17 | 2008-05-22 | Friedrich-Alexander-Universitaet Erlangen-Nuernberg | Method of differentially diagnosing dementias |
WO2008148098A2 (en) * | 2007-05-24 | 2008-12-04 | University Of Rochester | Detection of fragments of nectin-1 for the diagnosis of alzheimer's disease |
US20100028918A1 (en) * | 2008-07-31 | 2010-02-04 | Probiodrug Ag | Glutaminyl cyclase as a diagnostic/prognostic indicator for neurodegenerative diseases |
AU2009295357A1 (en) * | 2008-09-26 | 2010-04-01 | The University Of Melbourne | Alzheimer's disease biomarkers |
DE102009054057A1 (de) * | 2009-11-20 | 2011-05-26 | Charité - Universitätsmedizin Berlin (Charité) | Screening-Verfahren für Wirkstoffe für die Prophylaxe und Therapie neurodegenerativer Erkrankungen |
EP2511296A1 (de) | 2011-04-12 | 2012-10-17 | Araclón Biotech, S. L. | Antikörper, Kit und Verfahren zur Bestimmung von Amyloidpeptiden |
US9678086B2 (en) | 2012-09-10 | 2017-06-13 | The Johns Hopkins University | Diagnostic assay for Alzheimer's disease |
ES2498465B1 (es) * | 2013-02-20 | 2015-09-17 | Universidad Miguel Hernández De Elche | Método de diagnóstico y/o pronóstico de la enfermedad de alzheimer |
US20170336395A1 (en) * | 2013-11-20 | 2017-11-23 | University Of Iowa Research Foundation | Methods and compositions for treating amyloid deposits |
EP3783364A3 (de) | 2014-05-22 | 2021-05-19 | Shimadzu Corporation | Surrogatbiomarker zur beurteilung der intrazerebralen amyloid-beta-peptid-akkumulation und verfahren zur analyse davon |
CN105002172B (zh) * | 2015-07-31 | 2017-07-11 | 北京泱深生物信息技术有限公司 | 检测eapp基因表达的试剂在诊治阿尔茨海默病中的应用 |
EP4252243A2 (de) | 2020-11-30 | 2023-10-04 | Enigma Biointelligence, Inc. | Nichtinvasive beurteilung von morbus alzheimer |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998021589A1 (en) * | 1996-11-15 | 1998-05-22 | The Trustees Of The University Of Pennsylvania | Screening for modulators of amyloid processing |
KR100768381B1 (ko) * | 1998-09-24 | 2007-10-18 | 파마시아 앤드 업존 캄파니 엘엘씨 | 알츠하이머병 세크레타제 |
AU2001269127A1 (en) * | 2000-07-06 | 2002-01-14 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | A novel app mutation associated with an unusual alzheimer's disease pathology |
EP1421198A4 (de) * | 2001-06-26 | 2006-08-30 | New York State Office Of Menta | Screeningmethoden mit hohem durchsatz auf zellbasis |
WO2003040183A2 (en) * | 2001-11-09 | 2003-05-15 | The Genetics Company, Inc | Compounds for the diagnosis/prevention/treatment of alzheimer's disease |
WO2003103593A2 (en) * | 2002-06-05 | 2003-12-18 | Buck Institute | Secretases related to alzheimer's dementia |
ATE410696T1 (de) * | 2004-05-24 | 2008-10-15 | Univ Muenchen L Maximilians | Identizifierung von antiprionwirkstoffen mittels screening mit hohem durchsatz auf sift-basis |
-
2006
- 2006-06-08 ES ES06011829T patent/ES2373048T3/es active Active
- 2006-06-08 AT AT06011829T patent/ATE523788T1/de not_active IP Right Cessation
- 2006-06-08 EP EP06011829A patent/EP1865326B1/de not_active Not-in-force
-
2007
- 2007-04-20 EP EP07724441A patent/EP2032990A2/de not_active Withdrawn
- 2007-04-20 CN CNA2007800207984A patent/CN101460853A/zh active Pending
- 2007-04-20 US US12/303,898 patent/US20100221759A1/en not_active Abandoned
- 2007-04-20 WO PCT/EP2007/003505 patent/WO2007140843A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
EP1865326B1 (de) | 2011-09-07 |
WO2007140843A2 (en) | 2007-12-13 |
CN101460853A (zh) | 2009-06-17 |
EP1865326A1 (de) | 2007-12-12 |
US20100221759A1 (en) | 2010-09-02 |
WO2007140843A3 (en) | 2008-04-24 |
ES2373048T3 (es) | 2012-01-30 |
EP2032990A2 (de) | 2009-03-11 |
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Legal Events
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