JP5677297B2 - 神経変性疾患の診断／予後判定の指標としてのグルタミニルシクラーゼ - Google Patents

神経変性疾患の診断／予後判定の指標としてのグルタミニルシクラーゼ Download PDF

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JP5677297B2
JP5677297B2 JP2011520526A JP2011520526A JP5677297B2 JP 5677297 B2 JP5677297 B2 JP 5677297B2 JP 2011520526 A JP2011520526 A JP 2011520526A JP 2011520526 A JP2011520526 A JP 2011520526A JP 5677297 B2 JP5677297 B2 JP 5677297B2
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デムトフ ハンス−ウルリクフ
デムトフ ハンス−ウルリクフ
スチルリング ステプハン
スチルリング ステプハン
クルエインスクフミドト マルトイン
クルエインスクフミドト マルトイン
ラフフエルド ジェンス−ウルリクフ
ラフフエルド ジェンス−ウルリクフ
ケフルエン アストリド
ケフルエン アストリド
ボルナクク モニクエ
ボルナクク モニクエ
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プロビオドルグ エージー
プロビオドルグ エージー
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JP2011520526A 2008-07-31 2009-07-31 神経変性疾患の診断／予後判定の指標としてのグルタミニルシクラーゼ Active JP5677297B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8515408P 2008-07-31 2008-07-31
US61/085,154 2008-07-31
PCT/EP2009/059951 WO2010012828A2 (en) 2008-07-31 2009-07-31 Glutaminyl cyclase as a diagnostic / prognostic indicator for neurodegenerative diseases

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JP2011529571A JP2011529571A (ja) 2011-12-08
JP2011529571A5 JP2011529571A5 (OSRAM) 2012-09-20
JP5677297B2 true JP5677297B2 (ja) 2015-02-25

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US (3) US20100028918A1 (OSRAM)
EP (1) EP2329274B1 (OSRAM)
JP (1) JP5677297B2 (OSRAM)
KR (1) KR101682728B1 (OSRAM)
CN (2) CN103983787A (OSRAM)
AU (1) AU2009275869B2 (OSRAM)
BR (1) BRPI0916601B1 (OSRAM)
CA (1) CA2731933A1 (OSRAM)
EA (1) EA025107B1 (OSRAM)
IL (1) IL210266A (OSRAM)
MX (1) MX2011001093A (OSRAM)
NZ (1) NZ590658A (OSRAM)
SG (1) SG193148A1 (OSRAM)
WO (1) WO2010012828A2 (OSRAM)
ZA (1) ZA201100177B (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013519891A (ja) * 2010-02-18 2013-05-30 プロビオドルグ エージー ピログルタミン酸修飾ｍｃｐ−１を決定することにより炎症性疾患を診断する方法及びグルタミニルシクラーゼの阻害剤のスクリーニング方法
JP2014515364A (ja) 2011-05-27 2014-06-30 プロビオドルグ エージー 放射能標識グルタミニルシクラーゼ阻害剤
US20170363645A1 (en) 2014-12-19 2017-12-21 Probiodrug Ag Novel Method for the Detection of pGlu-Abeta Peptides
CN104946680A (zh) * 2015-06-11 2015-09-30 深圳大学 用于表达qc的重组载体及其制备方法、引物、基因工程菌
KR102362919B1 (ko) * 2016-07-08 2022-02-16 아지노모토 가부시키가이샤 경도 인지 장해 또는 알츠하이머형 인지증의 평가 방법
KR102858457B1 (ko) * 2023-06-07 2025-09-11 계명대학교 산학협력단 Ccl8 단백질 또는 이를 코딩하는 유전자를 유효성분으로 포함하는 퇴행성 뇌질환 진단용 바이오마커 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4374316B2 (ja) * 1993-01-25 2009-12-02 武田薬品工業株式会社 β−アミロイドまたはその誘導体に対する抗体およびその用途
JP3590468B2 (ja) * 1996-01-22 2004-11-17 財団法人 東京都医学研究機構 アルツハイマー病診断薬
EP1523499A2 (en) * 2002-07-24 2005-04-20 Innogenetics N.V. Fragments of beta-amyloid as targets for vaccination against alzheimer disease
US7732162B2 (en) * 2003-05-05 2010-06-08 Probiodrug Ag Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
MXPA05011861A (es) * 2003-05-05 2006-02-17 Probiodrug Ag Uso de efectores de ciclasas de glutamato y glutaminil.
CA2542419C (en) * 2003-10-15 2013-06-04 Probiodrug Ag Use of glutamyl cyclase inhibitors in the treatment of familial british dementia and familial danish dementia
US20060094064A1 (en) * 2003-11-19 2006-05-04 Sandip Ray Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids
KR101099206B1 (ko) * 2004-02-05 2011-12-27 프로비오드룩 아게 신규한 글루타미닐 시클라제 저해제
WO2006120104A1 (en) * 2005-04-11 2006-11-16 Probiodrug Ag Inhibitors of prolyl endopeptidase
ATE523788T1 (de) * 2006-06-08 2011-09-15 Fu Berlin ASSAY ZUR DIAGNOSE VON ALZHEIMER BASIEREND AUF DER BESTIMMUNG DES VERHÄLTNISSES VON SEKRETASE-Aß-SPALTPRODUKTEN
JP2010504088A (ja) * 2006-09-21 2010-02-12 プロビオドルグ エージー グルタミニルシクラーゼに関連した新規遺伝子
WO2008087197A1 (en) * 2007-01-19 2008-07-24 Probiodrug Ag In vivo screening models for treatment of alzheimer's disease and other qpct-related disorders

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Publication number Publication date
US20150247180A1 (en) 2015-09-03
BRPI0916601B1 (pt) 2021-05-25
SG193148A1 (en) 2013-09-30
JP2011529571A (ja) 2011-12-08
NZ590658A (en) 2012-07-27
HK1155813A1 (en) 2012-05-25
ZA201100177B (en) 2012-02-29
IL210266A0 (en) 2011-03-31
US20170097365A1 (en) 2017-04-06
CN103983787A (zh) 2014-08-13
IL210266A (en) 2016-04-21
EP2329274A2 (en) 2011-06-08
KR20110049781A (ko) 2011-05-12
CA2731933A1 (en) 2010-02-04
US20100028918A1 (en) 2010-02-04
KR101682728B1 (ko) 2016-12-05
EA025107B1 (ru) 2016-11-30
CN102112880A (zh) 2011-06-29
WO2010012828A3 (en) 2010-05-06
MX2011001093A (es) 2011-03-15
WO2010012828A2 (en) 2010-02-04
EA201100253A1 (ru) 2011-10-31
EP2329274B1 (en) 2015-12-02
CN102112880B (zh) 2014-06-25
BRPI0916601A2 (pt) 2015-11-10
AU2009275869A1 (en) 2010-02-04
AU2009275869B2 (en) 2015-05-21

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