JP2011520911A5 - - Google Patents
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- Publication number
- JP2011520911A5 JP2011520911A5 JP2011509733A JP2011509733A JP2011520911A5 JP 2011520911 A5 JP2011520911 A5 JP 2011520911A5 JP 2011509733 A JP2011509733 A JP 2011509733A JP 2011509733 A JP2011509733 A JP 2011509733A JP 2011520911 A5 JP2011520911 A5 JP 2011520911A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- betaine
- administered
- fluoroquinolone
- tobramycin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12778008P | 2008-05-15 | 2008-05-15 | |
| US61/127,780 | 2008-05-15 | ||
| PCT/US2009/044116 WO2009140587A1 (en) | 2008-05-15 | 2009-05-15 | Pulmonary delivery of a fluoroquinolone |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014251869A Division JP5989750B2 (ja) | 2008-05-15 | 2014-12-12 | フルオロキノロンの肺送達 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011520911A JP2011520911A (ja) | 2011-07-21 |
| JP2011520911A5 true JP2011520911A5 (https=) | 2012-07-05 |
| JP5727927B2 JP5727927B2 (ja) | 2015-06-03 |
Family
ID=41099304
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011509733A Active JP5727927B2 (ja) | 2008-05-15 | 2009-05-15 | フルオロキノロンの肺送達 |
| JP2014251869A Expired - Fee Related JP5989750B2 (ja) | 2008-05-15 | 2014-12-12 | フルオロキノロンの肺送達 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014251869A Expired - Fee Related JP5989750B2 (ja) | 2008-05-15 | 2014-12-12 | フルオロキノロンの肺送達 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8834930B2 (https=) |
| EP (1) | EP2285345A1 (https=) |
| JP (2) | JP5727927B2 (https=) |
| KR (1) | KR101621986B1 (https=) |
| CN (1) | CN102099009B (https=) |
| AU (1) | AU2009246217B2 (https=) |
| BR (1) | BRPI0913021A2 (https=) |
| CA (1) | CA2724009C (https=) |
| MX (1) | MX2010012452A (https=) |
| RU (1) | RU2497524C2 (https=) |
| WO (1) | WO2009140587A1 (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| US8546423B2 (en) | 2005-05-18 | 2013-10-01 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| JP5570996B2 (ja) | 2007-12-14 | 2014-08-13 | エアロデザインズ インコーポレイテッド | エアロゾル化可能な食料品の送達 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| CN101827626B (zh) | 2008-06-13 | 2015-03-18 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
| TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| JP2012505223A (ja) | 2008-10-07 | 2012-03-01 | エムペックス・ファーマシューティカルズ・インコーポレーテッド | 薬物動態の改善のためのエアゾールフルオロキノロン配合物 |
| EP2346509B1 (en) | 2008-10-07 | 2020-05-13 | Horizon Orphan LLC | Inhalation of levofloxacin for reducing lung inflammation |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| DK2405963T3 (da) | 2009-03-11 | 2013-12-16 | Mannkind Corp | Apparat, system og fremgangsmåde til at måle modstand i en inhalator |
| CA2754691C (en) | 2009-03-26 | 2019-07-30 | Pulmatrix, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| PT2421539T (pt) | 2009-04-24 | 2019-11-22 | Horizon Orphan Llc | Métodos de tratamento de uma infecção bacteriana pulmonar usando fluoroquinolonas |
| KR102584844B1 (ko) | 2009-06-12 | 2023-10-04 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| RU2563809C2 (ru) | 2009-09-04 | 2015-09-20 | Мпекс Фармасьютикалс, Инк. | Применение левофлоксацина в форме аэрозоля для лечения муковисцидоза |
| CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
| AU2011296343B2 (en) | 2010-08-30 | 2015-12-10 | Pulmatrix Operating Company, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| RU2017144619A (ru) | 2010-09-29 | 2019-02-20 | Пулмэтрикс, Инк. | Катионы одновалентных металлов сухих порошков для ингаляций |
| EP3470057B1 (en) * | 2010-09-29 | 2021-11-03 | Pulmatrix Operating Company, Inc. | Cationic dry powders comprising magnesium salt |
| SG194034A1 (en) | 2011-04-01 | 2013-11-29 | Mannkind Corp | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| MX2014004983A (es) | 2011-10-24 | 2014-09-22 | Mannkid Corp | Metodos y composiciones para tratar dolor. |
| RU2615076C2 (ru) * | 2011-12-16 | 2017-04-03 | Новартис Аг | Устройство аэрозолизации для независимой от профиля вдоха доставки лекарственного средства |
| CN107596518B (zh) | 2012-02-29 | 2021-04-23 | 普马特里克斯营业公司 | 可吸入干粉剂 |
| KR102264177B1 (ko) | 2012-07-12 | 2021-06-11 | 맨카인드 코포레이션 | 건조 분말 약물 전달 시스템 및 방법 |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| US9757529B2 (en) * | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| US9452139B2 (en) | 2013-03-14 | 2016-09-27 | Novartis Ag | Respirable agglomerates of porous carrier particles and micronized drug |
| EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
| JP6473738B2 (ja) | 2013-04-01 | 2019-02-20 | パルマトリックス,インコーポレイテッド | チオトロピウム乾燥粉末 |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| US10194693B2 (en) * | 2013-09-20 | 2019-02-05 | Fontem Holdings 1 B.V. | Aerosol generating device |
| US9427376B2 (en) * | 2013-10-10 | 2016-08-30 | Chiesi Farmaceutici S.P.A. | Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient |
| RU2016136449A (ru) * | 2014-02-28 | 2018-04-02 | АльгиФарма АС | Применение олигометов альгината в лечении муковисцидоза и других состояний, ассоциированных с нарушенной функцией ионных каналов cftr |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| EP3129004A4 (en) * | 2014-04-08 | 2017-11-15 | Aradigm Corporation | Liposomal ciprofloxacin formulations with activity against non-tuberculous mycobacteria |
| WO2016040575A1 (en) * | 2014-09-10 | 2016-03-17 | Fontem Holdings 1 B.V. | Methods and devices for modulating air flow in delivery devices |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| RU2681342C2 (ru) | 2015-01-22 | 2019-03-06 | Фонтем Холдингс 1 Б.В. | Электронные испарительные устройства |
| US20180303753A1 (en) * | 2015-09-09 | 2018-10-25 | Keith Try Ung | Targeted delivery of spray-dried formulations to the lungs |
| WO2020163416A1 (en) * | 2019-02-05 | 2020-08-13 | Mylan Inc | Devices and methods for tobramycin inhalation treatment |
| WO2024233921A1 (en) * | 2023-05-10 | 2024-11-14 | Cornell University | Compositions for the transtympanic delivery of antibiotics and methods for using the same |
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| IT1016489B (it) * | 1974-03-18 | 1977-05-30 | Isf Spa | Inalatore |
| SE408265B (sv) * | 1975-12-12 | 1979-06-05 | Draco Ab | Anordning for koldioxiddriven endosaerosol, avsedd for inhalering |
| US4247066A (en) * | 1978-02-21 | 1981-01-27 | General Dynamics Corporation | Airfoil variable cambering device and method |
| IT1116047B (it) * | 1979-04-27 | 1986-02-10 | Sigma Tau Ind Farmaceuti | Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma |
| DE3634952A1 (de) * | 1986-10-14 | 1988-04-21 | Bayer Ag | Imidazo-pyrrolo-pyridin-derivate |
| IT1228459B (it) * | 1989-02-23 | 1991-06-19 | Phidea S R L | Inalatore con svuotamento regolare e completo della capsula. |
| WO1993000951A1 (en) * | 1991-07-02 | 1993-01-21 | Inhale, Inc. | Method and device for delivering aerosolized medicaments |
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| US5508269A (en) * | 1994-10-19 | 1996-04-16 | Pathogenesis Corporation | Aminoglycoside formulation for aerosolization |
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| ES2237767T3 (es) * | 1995-04-14 | 2005-08-01 | Nektar Therapeutics | Composiciones farmaceuticas en polvo que tienen una dispersabilidad mejorada. |
| US5855913A (en) * | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
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| US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
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| TR200502522T2 (tr) | 2002-12-31 | 2005-09-21 | Nektar Therapeutics | Çözünmez bir aktif madde içeren farmasötik formülasyon |
| DE10305318A1 (de) | 2003-02-10 | 2004-08-19 | Bayer Healthcare Ag | Behandlung bakteriell verursachter Lungenkrankheiten |
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| JP4828405B2 (ja) | 2003-02-10 | 2011-11-30 | バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト | 呼吸器官の細菌性疾患の処置 |
| US7559325B2 (en) * | 2003-04-09 | 2009-07-14 | Novartis Pharma Ag | Aerosolization apparatus with air inlet shield |
| HUE026950T2 (en) * | 2003-04-09 | 2016-08-29 | Novartis Ag | Nozzle with guide wire for puncturing the capsule |
| WO2005044226A2 (en) * | 2003-11-04 | 2005-05-19 | Nectar Therapeutics | Lipid formulations for spontaneous drug encapsulation |
| MXPA06014567A (es) | 2004-06-18 | 2007-07-24 | Novartis Vaccines & Diagnostic | Metodo para el tratamiento de infecciones endobronquiales. |
| MXPA06015220A (es) * | 2004-06-21 | 2007-12-13 | Nektar Therapeutics | Composiciones comprendiendo anfotericina b, metodos y sistemas. |
| WO2006033713A2 (en) * | 2004-08-09 | 2006-03-30 | Chiron Corporation | Methods for ciprofloxacin inhalation |
| TWI254288B (en) * | 2004-09-30 | 2006-05-01 | Benq Corp | Optical disk drive with mechanism of protecting pick-up head |
| EP1901749B1 (en) | 2005-05-18 | 2016-08-03 | Raptor Pharmaceuticals Inc. | Aerosolized fluoroquinolones and uses thereof |
| US20060280691A1 (en) * | 2005-06-13 | 2006-12-14 | University Of Alberta | Spray freeze dried liposomal ciprofloxacin powder aerosol drug delivery |
| US7947308B2 (en) * | 2005-07-20 | 2011-05-24 | Raimar Loebenberg | Effervescent powders for inhalation |
| US7256576B2 (en) * | 2005-07-29 | 2007-08-14 | General Electric Company | ID-OD discrimination sensor |
| DE102005036921A1 (de) | 2005-08-05 | 2007-02-08 | Bayerische Motoren Werke Ag | Pulsationsminderer für hydraulische Systeme |
-
2009
- 2009-05-15 WO PCT/US2009/044116 patent/WO2009140587A1/en not_active Ceased
- 2009-05-15 BR BRPI0913021A patent/BRPI0913021A2/pt not_active Application Discontinuation
- 2009-05-15 EP EP09747668A patent/EP2285345A1/en not_active Withdrawn
- 2009-05-15 CN CN200980127383.6A patent/CN102099009B/zh not_active Expired - Fee Related
- 2009-05-15 US US12/992,371 patent/US8834930B2/en not_active Expired - Fee Related
- 2009-05-15 CA CA2724009A patent/CA2724009C/en not_active Expired - Fee Related
- 2009-05-15 KR KR1020107028079A patent/KR101621986B1/ko not_active Expired - Fee Related
- 2009-05-15 AU AU2009246217A patent/AU2009246217B2/en not_active Ceased
- 2009-05-15 RU RU2010150839/15A patent/RU2497524C2/ru not_active IP Right Cessation
- 2009-05-15 JP JP2011509733A patent/JP5727927B2/ja active Active
- 2009-05-15 MX MX2010012452A patent/MX2010012452A/es active IP Right Grant
-
2014
- 2014-08-12 US US14/457,162 patent/US9155732B2/en not_active Expired - Fee Related
- 2014-12-12 JP JP2014251869A patent/JP5989750B2/ja not_active Expired - Fee Related
-
2015
- 2015-09-03 US US14/844,373 patent/US20150374685A1/en not_active Abandoned
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